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Ojo, O. O. and Leake, D. (2022) Effects of lysosomal low density lipoprotein oxidation by ferritin on macrophage function. Free Radical Research. GFRR-OM-2022-0211. ISSN 1071-5762 doi: https://doi.org/10.1080/10715762.2022.2133703

Ahmad, F., Mitchell, R., Houben, T., Palo, A., Yasdati, T., Parnell, A., Patel, K., Shiri-Sverdlov, R. and Leake, D. (2021) Cysteamine decreases low density lipoprotein oxidation, causes regression of atherosclerosis and improves liver and muscle function in LDL receptor deficient mice. JAHA: Journal of the American Heart Association, 10 (18). ISSN 2047-9980 doi: https://doi.org/10.1161/JAHA.120.017524

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Ojo, O. O. and Leake, D. S. (2021) Vitamins E and C do not effectively inhibit low density lipoprotein oxidation by ferritin at lysosomal pH. Free Radical Research, 55 (5). pp. 525-534. ISSN 1071-5762 doi: https://doi.org/10.1080/10715762.2021.1964494

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Bhatti, S. N., Leidi, A., Leake, D. and Li, J.-m. ORCID: https://orcid.org/0000-0002-3294-3818 (2020) Studying biological science does not lead to adoption of a healthy lifestyle. Perspectives in Public Health, 140 (4). pp. 232-239. ISSN 1757-9139 doi: https://doi.org/10.1177/1757913919890889

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Ahmad, F. and Leake, D. S. (2019) Lysosomal oxidation of LDL alters lysosomal pH, induces senescence and increases secretion of pro-inflammatory cytokines in human macrophages. Journal of Lipid Research, 60. pp. 98-110. ISSN 1539-7262 doi: https://doi.org/10.1194/jlr.M088245

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Palmer, C., Peri, F., Neumann, F., Ahmad, F., Leake, D. S. and Pirianov, G. (2018) The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates in vitro and in vivo haematopoietic and non-haematopoietic vascular TLR4 signalling. Innate Immunity, 24 (7). pp. 411-421. ISSN 1753-4267 doi: https://doi.org/10.1177/1753425918798904

Ahmad, F. and Leake, D. (2018) Antioxidants inhibit low density lipoprotein oxidation less at lysosomal pH: a possible explanation as to why the clinical trials of antioxidants might have failed. Chemistry and Physics of Lipids, 213. pp. 13-24. ISSN 0009-3084 doi: https://doi.org/10.1016/j.chemphyslip.2018.03.001

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Gerry, A. B. and Leake, D. S. (2014) Effect of low extracellular pH on NF-κB activation in macrophages. Atherosclerosis, 233 (2). pp. 537-544. ISSN 0021-9150 doi: https://doi.org/10.1016/j.atherosclerosis.2014.01.014

Wraith, K. S., Magwenzi, S., Aburima, A., Wen, Y., Leake, D. and Naseem, K. M. (2013) Oxidised low-density lipoproteins induce rapid platelet activation and shape change through tyrosine kinase and Rho kinase-signaling pathways. Blood, 122 (4). pp. 580-589. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2013-04-491688

Satchell, L. and Leake, D. (2012) Oxidation of low density lipoprotein by iron at lysosomal pH: implications for atherosclerosis. Biochemistry, 51 (18). pp. 3767-3775. ISSN 0006-2960 doi: https://doi.org/10.1021/bi2017975

Gieseg, S. P., Leake, D. S., Flavall, E. M., Amit, Z., Reid, L. and Yang, Y. T. (2009) Macrophage antioxidant protection within atherosclerotic plaques. Frontiers in Bioscience, 1 (14). pp. 1230-1246. ISSN 1093-9946 doi: https://doi.org/10.2741/3305

Gomez-Ruiz, J. A., Ames, J. M. and Leake, D. S. (2008) Antioxidant activity and protective effects of green and dark coffee components against human low density lipoprotein oxidation. European Food Research and Technology, 227 (4). pp. 1017-1024. ISSN 1438-2377 doi: https://doi.org/10.1007/s00217-007-0815-5

Gerry, A. B. and Leake, D. S. (2008) A moderate reduction in extracellular pH protects macrophages against apoptosis induced by oxidised low density lipoprotein. Journal of Lipid Research, 49 (4). pp. 782-789. ISSN 1539-7262 doi: https://doi.org/10.1194/jlr.M700349-JLR200

Gerry, A. B., Satchell, L. and Leake, D. S. (2008) A novel method for production of lipid hydroperoxide- or oxysterol-rich low-density lipoprotein. Atherosclerosis, 197 (2). pp. 579-587. ISSN 0021-9150 doi: https://doi.org/10.1016/j.atherosclerosis.2007.08.026

Kappler, M., Gerry, A. B., Brown, E., Reid, L., Leake, D. S. and Gieseg, S. P. (2007) Aqueous peroxyl radical exposure to THP-1 cells causes glutathione loss followed by protein oxidation and cell death without increased caspase-3 activity. Biochimica Et Biophysica Acta-Molecular Cell Research, 1773 (6). pp. 945-953. ISSN 0167-4889 doi: https://doi.org/10.1016/j.bbamcr.2007.04.001

Wong, W. M. R., Gerry, A. B., Putt, W., Roberts, J. L., Weinberg, R. B., Humphries, S. E., Leake, D. S. and Talmud, P. J. (2007) Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation. Atherosclerosis, 192 (2). pp. 266-274. ISSN 0021-9150 doi: https://doi.org/10.1016/j.atherosclerosis.2006.07.017

Gomez-Ruiz, J. A., Leake, D. S. and Ames, J. M. (2007) In vitro antioxidant activity of coffee compounds and their metabolites. Journal of Agricultural and Food Chemistry, 55 (17). pp. 6962-6969. ISSN 0021-8561 doi: https://doi.org/10.1021/jf0710985

Wen, Y. and Leake, D. S. (2007) Low density lipoprotein undergoes oxidation within lysosomes in cells. Circulation Research, 100. pp. 1337-1343. ISSN 0009-7330 doi: https://doi.org/10.1161/CIRCRESAHA.107.151704

Wen, Y. C. and Leake, D. S. (2007) Low density lipoprotein undergoes oxidation within lysosomes in cells. Circulation Research, 100 (9). pp. 1337-1343. ISSN 0009-7330 doi: https://doi.org/10.1161/circresaha.107.151704

Horsley, E. T. M., Burkitt, M. J., Jones, C. M. ORCID: https://orcid.org/0000-0001-7537-1509, Patterson, R. A., Harris, L. K., Moss, N. J., del Rio, J. D. and Leake, D. S. (2007) Mechanism of the antioxidant to pro-oxidant switch in the behavior of dehydroascorbate during LDL oxidation by copper(II) ions. Archives of Biochemistry and Biophysics, 465 (2). pp. 303-314. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2007.07.005

Harris, L. K., Mann, G. E., Ruiz, E., Mushtaq, S. and Leake, D. S. (2006) Ascorbate does not protect macrophages against apoptosis induced by oxidised low density lipoprotein. Archives of Biochemistry and Biophysics, 455 (1). pp. 68-76. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2006.07.019

Tricon, S., Burdge, G.C., Jones, E.L., Russell, J.J., El-Khazen, S., Moretti, E., Hall, W.L., Gerry, A.B., Leake, D.S., Grimble, R.F., Williams, C.M., Calder, P.C. and Yaqoob, P. (2006) Effects of dairy products naturally enriched with cis-9,trans-11 conjugated linoleic acid on the blood lipid profile in healthy middle-aged men. American Journal of Clinical Nutrition, 83 (4). pp. 744-753. ISSN 0002-9165

Jackson, K.G. ORCID: https://orcid.org/0000-0002-0070-3203, Maitin, V., Leake, D.S., Yaqoob, P. and Williams, C.M. (2006) Saturated fat-induced changes in S-f 60-400 particle composition reduces uptake of LDL by HepG2 cells. Journal of Lipid Research, 47 (2). pp. 393-403. ISSN 0022-2275 doi: https://doi.org/10.1194/jlr.M500382-JLR200

Anwar, A. A., Li, F. Y. L., Leake, D. S., Ishii, T., Mann, G. E. and Siow, R. C. M. (2005) Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: role of mitogen-activated protein kinases and Nrf2. Free Radical Biology and Medicine, 39 (2). pp. 227-236. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2005.03.012

Anwar, A. A., Leake, D. S. and Siow, R. C. M. (2004) MAPK pathways mediate induction of heme oxygenase-1 and glutathione by moderately oxidized low density lipoproteins in vascular smooth muscle cells. Free Radical Biology and Medicine, 36. S44-S44. ISSN 0891-5849

Ishii, T., Itoh, K., Ruiz, E., Leake, D. S., Unoki, H., Yamamoto, M. and Mann, G. E. (2004) Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages - Activation by oxidatively modified LDL and 4-hydroxynonenal. Circulation Research, 94 (5). pp. 609-616. ISSN 0009-7330 doi: https://doi.org/10.1161/01.res.0000119171.44657.45

Kavanagh, I.C., Symes, C.E., Renaudin, P., Nova, E., Mesa, M.D., Boukouvalas, G., Leake, D.S. and Yaqoob, P. (2003) Degree of oxidation of low density lipoprotein affects expression of CD36 and PPAR gamma, but not cytokine production, by human monocyte-macrophages. Atherosclerosis, 168 (2). pp. 271-282. ISSN 0021-9150 doi: https://doi.org/10.1016/s0021-9150(03)00148-5

Patterson, R. A., Lamb, D. J. and Leake, D. S. (2003) Mechanisms by which cysteine can inhibit or promote the oxidation of low density lipoprotein by copper. Atherosclerosis, 169 (1). pp. 87-94. ISSN 0021-9150 doi: https://doi.org/10.1016/s0021-9150(03)00154-0

Talbot, R. M., del Rio, J. D., Leake, D. S. and Weinberg, P. D. (2003) Oxidation affects the flow-induced aggregation of low density lipoprotein and its inhibition by albumin. Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids, 1634 (1-2). pp. 24-29. ISSN 1388-1981 doi: https://doi.org/10.1016/j.bbalip.2003.08.002

Patterson, R. A., Horsley, E. T. M. and Leake, D. S. (2003) Prooxidant and antioxidant properties of human serum ultrafiltrates toward LDL: important role of uric acid. Journal of Lipid Research, 44 (3). pp. 512-521. ISSN 0022-2275 doi: https://doi.org/10.1194/jlr.M200407-JLR200

Alderman, C. J. J., Bunyard, P. R., Chain, B. M., Foreman, J. C., Leake, D. and Katz, D. R. (2002) Effects of oxidised low density lipoprotein on dendritic cells: a possible immunoregulatory component of the atherogenic micro-environment? Cardiovascular Research, 55 (4). pp. 806-819. ISSN 0008-6363 doi: https://doi.org/10.1016/S0008-6363(02)00447-9

Leigh-Firbank, E. C., Minihane, A. M., Leake, D. S., Wright, J. W., Murphy, M. C., Griffin, B. A. and Williams, C. M. (2002) Eicosapentaenoic acid and docosahexaenoic acid from fish oils: differential associations with lipid responses. British Journal of Nutrition, 87. pp. 435-445. ISSN 0007-1145 doi: https://doi.org/10.1079/BJN2002556