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Items where Author is "Pollitt, Dr Alice"

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Dunster, J. L., Unsworth, A. J., Bye, A. P., Haining, E. J.,, Sowa, M. A., Di, Y., Sage, T., Pallini, C., Pike, J. A., Hardy, A. T., Nieswandt, B., García, Á., Watson, S. P., Poulter, N. S., Gibbins, J. M. and Pollitt, A. Y. (2019) Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation. Journal of Thrombosis and Haemostasis. ISSN 1538-7933 doi: https://doi.org/10.1111/jth.14673

Nicolson, P. L. R., Hughes, C. E., Watson, S., Nock, S. H., Hardy, A. T., Watson, C. N., Montague, S. J., Malcor, J.-D., Thomas, M. R., Pollitt, A. Y., Tomlinson, M. G., Pratt, G. and Watson, S. P. (2018) Inhibition of Btk by Btk-specific concentrations of ibrutinib and acalabrutinib delays but does not block platelet aggregation to GPVI. Haematologica, 103 (12). pp. 2097-2108. ISSN 1592-8721 doi: https://doi.org/10.3324/haematol.2018.193391

Lombard, S. E., Pollitt, A. Y., Hughes, C. E., Di, Y., Mckinnon, T., O'Callaghan, C. A. and Watson, S. P. (2018) Mouse podoplanin supports adhesion and aggregation of platelets under arterial shear: a novel mechanism of haemostasis. Platelets, 29 (7). pp. 716-722. ISSN 0953-7104 doi: https://doi.org/10.1080/09537104.2017.1356919

Poulter, N. S., Pollitt, A. Y., Owen, D. M., Gardiner, E. E., Andrews, R. K., Shimizu, H., Ishikawa, D., Bihan, D., Farndale, R. W., Moroi, M., Watson, S. P. and Jung, S. M. (2017) Clustering of GPVI dimers upon adhesion to collagen as a mechanism to regulate GPVI signalling in platelets. Journal of Thrombosis and Haemostasis, 15 (3). pp. 549-564. ISSN 1538-7933 doi: https://doi.org/10.1111/jth.13613

Alshehri, O. M., Montague, S., Watson, S., Carter, P., Sarker, N., Manne, B. K., Miller, J. L. C., Herr, A. B., Pollitt, A. Y., O'Callaghan, C. A., Kunapuli, S., Arman, M., Hughes, C. E. and Watson, S. P. (2015) Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands. Biochemical Journal, 468 (3). pp. 459-473. ISSN 0264-6021 doi: https://doi.org/10.1042/BJ20150192

Poulter, N. S., Pollitt, A. Y., Davies, A., Malinova, D., Nash, G. B., Hannon, M. J., Pikramenou, Z., Rappoport, J. Z., Hartwig, J. H., Owen, D. M., Thrasher, A. J., Watson, S. P. and Thomas, S. G. (2015) Platelet actin nodules are podosome-like structures dependent on Wiskott-Aldrich syndrome protein and ARP2/3 complex. Nature Communications, 6. 7254. ISSN 2041-1723 doi: https://doi.org/10.1038/ncomms8254

Navarro-Núñez, L., Pollitt, A. Y., Lowe, K., Latif, A., Nash, G. B. and Watson, S. P. (2015) Platelet adhesion to podoplanin under flow is mediated by the receptor CLEC-2 and stabilised by Src/Syk-dependent platelet signalling. Thrombosis and haemostasis, 113 (5). pp. 1109-1120. ISSN 0340-6245 doi: https://doi.org/10.1160/TH14-09-0762

Flierl, U., Nero, T. L., Lim, B., Arthur, J. F., Yao, Y., Jung, S. M., Gitz, E., Pollitt, A. Y., Zaldivia, M. T. K., Jandrot-Perrus, M., Schäfer, A., Nieswandt, B., Andrews, R. K., Parker, M. W., Gardiner, E. E. and Peter, K. (2015) Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators. The Journal of Experimental Medicine, 212 (2). pp. 129-137. ISSN 1540-9538 doi: https://doi.org/10.1084/jem.20140391

Pollitt, A. Y., Poulter, N. S., Gitz, E., Navarro-Nuñez, L., Wang, Y.-J., Hughes, C. E., Thomas, S. G., Nieswandt, B., Douglas, M. R., Owen, D. M., Jackson, D. G., Dustin, M. L. and Watson, S. P. (2014) Syk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells. The Journal of Biological Chemistry, 289 (52). pp. 35695-35710. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M114.584284

Gitz, E., Pollitt, A. Y., Gitz-Francois, J. J., Alshehri, O., Mori, J., Montague, S., Nash, G. B., Douglas, M. R., Gardiner, E. E., Andrews, R. K., Buckley, C. D., Harrison, P. and Watson, S. P. (2014) CLEC-2 expression is maintained on activated platelets and on platelet microparticles. Blood, 124 (14). pp. 2262-2270. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2014-05-572818

Borgognone, A., Navarro-Núñez, L., Correia, J. N., Pollitt, A. Y., Thomas, S. G., Eble, J. A., Pulcinelli, F. M., Madhani, M. and Watson, S. P. (2014) CLEC-2-dependent activation of mouse platelets is weakly inhibited by cAMP but not by cGMP. Journal of Thrombosis and Haemostasis, 12 (4). pp. 550-559. ISSN 1538-7933 doi: https://doi.org/10.1111/jth.12514

Ura, S., Pollitt, A. Y., Veltman, D. M., Morrice, N. A., Machesky, L. M. and Insall, R. H. (2012) Pseudopod growth and evolution during cell movement is controlled through SCAR/WAVE dephosphorylation. Current Biology, 22 (7). pp. 553-561. ISSN 0960-9822 doi: https://doi.org/10.1016/j.cub.2012.02.020

Finney, B. A., Schweighoffer, E., Navarro-Núñez, L., Bénézech, C., Barone, F., Hughes, C. E., Langan, S. A., Lowe, K. L., Pollitt, A. Y., Mourao-Sa, D., Sheardown, S., Nash, G. B., Smithers, N., Reis e Sousa, C., Tybulewicz, V. L. J. and Watson, S. P. (2012) CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development. Blood, 119 (7). pp. 1747-1756. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2011-09-380709

Séverin, S., Pollitt, A. Y., Navarro-Nuñez, L., Nash, C. A., Mourão-Sá, D., Eble, J. A., Senis, Y. A. and Watson, S. P. (2011) Syk-dependent phosphorylation of CLEC-2: a novel mechanism of hem-immunoreceptor tyrosine-based activation motif signalling. The Journal of Biological Chemistry, 286 (6). pp. 4107-4116. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M110.167502

Hughes, C. E., Navarro-Núñez, L., Finney, B. A., Mourão-Sá, D., Pollitt, A. Y. and Watson, S. P. (2010) CLEC-2 is not required for platelet aggregation at arteriolar shear. Journal of Thrombosis and Haemostasis, 8 (10). pp. 2328-2332. ISSN 1538-7933 doi: https://doi.org/10.1111/j.1538-7836.2010.04006.x

Falet, H., Pollitt, A. Y., Begonja, A. J., Weber, S. E., Duerschmied, D., Wagner, D. D., Watson, S. P. and Hartwig, J. H. (2010) A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function. The Journal of Experimental Medicine, 207 (9). pp. 1967-1979. ISSN 1540-9538 doi: https://doi.org/10.1084/jem.20100222

Watson, S. P., Herbert, J. M. J. and Pollitt, A. Y. (2010) GPVI and CLEC-2 in hemostasis and vascular integrity. Journal of Thrombosis and Haemostasis, 8 (7). pp. 1456-1467. ISSN 1538-7933 doi: https://doi.org/10.1111/j.1538-7836.2010.03875.x

Hughes, C. E., Pollitt, A. Y., Mori, J., Eble, J. A., Tomlinson, M. G., Hartwig, J. H., O'Callaghan, C. A., Fütterer, K. and Watson, S. P. (2010) CLEC-2 activates Syk through dimerization. Blood, 115 (14). pp. 2947-2955. ISSN 1528-0020 doi: https://doi.org/10.1182/blood-2009-08-237834

Pollitt, A. Y., Grygielska, B., Leblond, B., Désiré, L., Eble, J. A. and Watson, S. P. (2010) Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization, secondary mediators, and Rac. Blood, 115 (14). pp. 2938-2946. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2009-12-257212

Pollitt, A. Y. and Insall, R. H. (2009) WASP and SCAR/WAVE proteins: the drivers of actin assembly. Journal of cell science, 122 (Pt 15). pp. 2575-8. ISSN 0021-9533

Spalton, J. C., Mori, J., Pollitt, A. Y., Hughes, C. E., Eble, J. A. and Watson, S. P. (2009) The novel Syk inhibitor R406 reveals mechanistic differences in the initiation of GPVI and CLEC-2 signaling in platelets. Journal of thrombosis and haemostasis : JTH, 7 (7). pp. 1192-9. ISSN 1538-7836

Pollitt, A. Y. and Insall, R. H. (2009) Loss of Dictyostelium HSPC300 causes a scar-like phenotype and loss of SCAR protein. BMC cell biology, 10. p. 13. ISSN 1471-2121

Christou, C. M., Pearce, A. C., Watson, A. A., Mistry, A. R., Pollitt, A. Y., Fenton-May, A. E., Johnson, L. A., Jackson, D. G., Watson, S. P. and O'Callaghan, C. A. (2008) Renal cells activate the platelet receptor CLEC-2 through podoplanin. The Biochemical journal, 411 (1). pp. 133-40. ISSN 1470-8728

Pollitt, A. Y. and Insall, R. H. (2008) Abi mutants in Dictyostelium reveal specific roles for the SCAR/WAVE complex in cytokinesis. Current biology : CB, 18 (3). pp. 203-10. ISSN 0960-9822

Pollitt, A. Y., Blagg, S. L., Ibarra, N. and Insall, R. H. (2006) Cell motility and SCAR localisation in axenically growing Dictyostelium cells. European journal of cell biology, 85 (9-10). pp. 1091-8. ISSN 0171-9335

Ibarra, N., Pollitt, A. Y. and Insall, R. H. (2005) Regulation of actin assembly by SCAR/WAVE proteins. Biochemical Society transactions, 33 (Pt 6). pp. 1243-6. ISSN 0300-5127

Book or Report Section

Dustin, M. L. and Pollitt, A. Y. (2018) The study of platelet receptors using artificial lipid bilayers. In: Gibbins, J. M. and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Methods in Molecular Biology, 1812. Humana Press, New York, pp. 127-137. ISBN 9781493985845 doi: https://doi.org/10.1007/978-1-4939-8585-2_8

Pollitt, A. Y., Hughes, C. E. and Watson, S. P. (2013) GPVI and CLEC-2. In: Michelson, A. D. (ed.) Platelets. 3rd edition. Academic Press, Amsterdam, pp. 215-231. ISBN 9780123878373 doi: https://doi.org/10.1016/B978-0-12-387837-3.00011-0

This list was generated on Fri Dec 13 23:37:38 2019 UTC.

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