Adipose tissue metabolism in pregnancy: the lipolytic effect of human placental lactogenColtart, T. M. and Williams, C. M. (1978) Adipose tissue metabolism in pregnancy: the lipolytic effect of human placental lactogen. British Journal of Obstetrics and Gynaecology, 85 (1). pp. 43-46. ISSN 0306-5456 Full text not archived in this repository. It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing. To link to this item DOI: 10.1111/j.1471-0528.1978.tb15824.x Abstract/SummaryIn vitro adipose tissue lipolysis was investigated in pregnant and non-pregnant women. Basal and hormone-stimulated rates of lipolysis were significantly higher in the pregnant group. Human placental lactogen (HPL) was shown to be lipolytic on adipose tissue from both pregnant and non-pregnant women; the response being more marked in the pregnant group. We postulate that HPL is responsible for this increased lipolytic sensitivity in pregnancy, the result of which is the elevation in levels of plasma free fatty acids in the third trimester.
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