Article

Vauzour, D., Corsini, S., Müller, M. and Spencer, J. P. E. (2018) Inhibition of PP2A by hesperetin may contribute to Akt and ERK1/2 activation status in cortical neurons. Archives of Biochemistry and Biophysics, 650. pp. 14-21. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2018.04.020

Vauzour, D., Camprubi-Robles, M., Miquel-Kergoat, S., Andres-Lacueva, C., Bánáti, D., Barberger-Gateau, P., Bowman, G. L., Caberlotto, L., Clarke, R., Hogervorst, E., Kiliaan, A. J., Lucca, U., Manach, C., Minihane, A.-M., Mitchell, E. S., Perneczky, R., Perry, H., Roussel, A.-M., Schuermans, J., Sijben, J., Spencer, J. P. E., Thuret, S., van de Rest, O., Vandewoude, M., Wesnes, K., Williams, R. J., Williams, R. S. B. and Ramirez, M. (2017) Nutrition for the ageing brain: towards evidence for an optimal diet. Ageing research reviews, 35. pp. 222-240. ISSN 1568-1637 doi: https://doi.org/10.1016/j.arr.2016.09.010

Neshatdoust, S., Saunders, C., Castle, S. M., Vauzour, D., Williams, C., Butler, L., Lovegrove, J. A. and Spencer, J. P. E. (2016) High-flavonoid intake induces cognitive improvement linked to changes in serum brain-derived neurotrophic factor: two randomised,controlled trials. Nutrition and Healthy Ageing, 4 (1). pp. 81-93. ISSN 2451-9502 doi: https://doi.org/10.3233/NHA-1615

Rendeiro, C., Foley, A., Lau, V. C., Ring, R., Rodriguez-Mateos, A., Vauzour, D., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X, Regan, C. and Spencer, J. P. E. (2014) A role for hippocampal PSA-NCAM and NMDA-NR2B receptor function in flavonoid-induced spatial memory improvements in young rats. Neuropharmacology, 79. pp. 335-344. ISSN 0028-3908 doi: https://doi.org/10.1016/j.neuropharm.2013.12.003

Rendeiro, C., Vauzour, D., Rattray, M., Waffo-Téguo, P., Mérillon, J. M., Butler, L. T., Williams, C. M. and Spencer, J. P. E. (2013) Dietary levels of pure flavonoids improve spatial memory performance and increase hippocampal brain-derived neurotrophic factor. PLoS ONE, 8 (5). e63535. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0063535

Corona, G., Vauzour, D., Hercelin, J., Williams, C. M. and Spencer, J. P. E. (2013) Phenolic acid intake, delivered via moderate champagne wine consumption, improves spatial working memory via the modulation of hippocampal and cortical protein expression/activation. Antioxidants & Redox Signaling, 19 (4). pp. 1676-1689. ISSN 1523-0864 doi: https://doi.org/10.1089/ars.2012.5142

Eid, N. M. S., Al-Awadi, B., Vauzour, D., Oruna-Concha, M. J. and Spencer, J. P. E. (2013) Effect of cultivar type and ripening on the polyphenol content of date palm fruit. Journal of Agricultural and Food Chemistry, 61 (10). pp. 2453-2460. ISSN 0021-8561 doi: https://doi.org/10.1021/jf303951e

Rendeiro, C., Vauzour, D., Kean, R. J., Butler, L. T., Rattray, M., Spencer, J. P. E. and Williams, C. M. (2012) Blueberry supplementation induces spatial memory improvements and region-specific regulation of hippocampal BDNF mRNA expression in young rats. Psychopharmacology, 223 (3). pp. 319-330. ISSN 0033-3158 doi: https://doi.org/10.1007/s00213-012-2719-8

Spilsbury, A., Vauzour, D., Spencer, J. P. and Rattray, M. (2012) Regulation of NF-κB activity in astrocytes: effects of flavonoids at dietary-relevant concentrations. Biochemical and Biophysical Research Communications, 418. pp. 578-583. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2012.01.081

Vauzour, D., Corona, G., Hercelin, J., Garnotel, R., Gillery, P., Lovegrove, J. A., Williams, C. M. and Spencer, J. P. E. (2011) Potential health effects of Champagne wine consumption. Journal of Wine Research, 22 (2). pp. 175-180. ISSN 1469-9672 doi: https://doi.org/10.1080/09571264.2011.603251

Vauzour, D., Houseman, E.J., George, T.W., Corona, G., Garnotel, R., Jackson, K.G., Sellier, C., Gillery, P., Kennedy, O.B., Lovegrove, J.A. and Spencer, J.P.E. (2010) Moderate Champagne consumption promotes an acute improvement in acute endothelial-independent vascular function in healthy human volunteers. British Journal of Nutrition, 103 (8). pp. 1168-1178. ISSN 0007-1145 doi: https://doi.org/10.1017/S0007114509992959

Vauzour, D., Corona, G. and Spencer, J. P. (2010) Caffeic acid, tyrosol and p-coumaric acid are potent inhibitors of 5-S-cysteinyl-dopamine induced neurotoxicity. Archives of Biochemistry and Biophysics, 501 (1). pp. 106-111. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2010.03.016

Incani, A., Deiana, M., Corona, G., Vafeiadou, K., Vauzour, D., Dessi, M. A. and Spencer, J. (2010) Involvement of ERK, Akt and JNK signalling in H2O2-induced cell injury and protection by hydroxytyrosol and its metabolite homovanillic alcohol. Molecular Nutrition & Food Research, 54 (6). pp. 788-796. ISSN 1613-4125 doi: https://doi.org/10.1002/mnfr.200900098

Vauzour, D., Buonfiglio, M., Corona, G., Chirafisi, J., Vafeiadou, K., Angeloni, C., Hrelia, S., Hrelia, P. and Spencer, J. P. E. (2010) Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes. Molecular Nutrition & Food Research, 54 (4). pp. 532-542. ISSN 1613-4125 doi: https://doi.org/10.1002/mnfr.200900197

Spencer, J. P. E., Vauzour, D. and Rendeiro, C. (2009) Flavonoids and cognition: The molecular mechanisms underlying their behavioural effects. Archives of Biochemistry and Biophysics, 492 (1-2). pp. 1-9. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2009.10.003

Corona, G., Deiana, M., Incani, A., Vauzour, D., Dessi, M. A. and Spencer, J. P. E. (2009) Hydroxytyrosol inhibits the proliferation of human colon adenocarcinoma cells through inhibition of ERK1/2 and cyclin D1. Molecular Nutrition & Food Research, 53 (7). pp. 897-903. ISSN 1613-4125 doi: https://doi.org/10.1002/mnfr.200800269

Vafeiadou, K., Vauzour, D., Lee, H. Y., Rodriguez-Mateos, A., Williams, R. J. and Spencer, J. P. E. (2009) The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury. Archives of Biochemistry and Biophysics, 484 (1). pp. 100-109. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2009.01.016

Rendeiro, C., Spencer, J. P. E., Vauzour, D., Butler, L. T., Ellis, J. A. and Williams, C. M. (2009) The impact of flavonoids on spatial memory in rodents: from behaviour to underlying hippocampal mechanisms. Genes and Nutrition, 4 (4). pp. 251-270. ISSN 1555-8932 doi: https://doi.org/10.1007/s12263-009-0137-2

Vafeiadou, K., Vauzour, D., Rodriguez-Mateos, A., Whiteman, M., Williams, R. J. and Spencer, J. P. E. (2008) Glial metabolism of quercetin reduces its neurotoxic potential. Archives of Biochemistry and Biophysics, 478 (2). pp. 195-200. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2008.07.014

Vauzour, D., Ravaioli, G., Vafeiadou, K., Rodriguez-Mateos, A., Angeloni, C. and Spencer, J. P. E. (2008) Peroxynitrite induced formation of the neurotoxins 5-S-cysteinyl-dopamine and DHBT-1: implications for Parkinson's disease and protection by polyphenols. Archives of Biochemistry and Biophysics, 476 (2). pp. 145-151. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2008.03.011

Cooper, A. J. L., Pinto, J. T., Krasnikov, B. F., Niatsetskaya, Z. V., Han, Q., Li, J. Y., Vauzour, D. and Spencer, J. P. E. (2008) Substrate specificity of human glutamine transaminase K as an aminotransferase and as a cysteine S-conjugate beta-lyase. Archives of Biochemistry and Biophysics, 474 (1). pp. 72-81. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2008.02.038

Vauzour, D., Vafeiadou, K., Rodriguez-Mateos, A., Rendeiro, C. and Spencer, J.P.E. (2008) The neuroprotective potential of flavonoids: a multiplicity of effects. Genes and Nutrition, 3 (3-4). pp. 115-126. ISSN 1555-8932 doi: https://doi.org/10.1007/s12263-008-0091-4

Vauzour, D., Vafeiadou, K., Rice-Evans, C., Williams, R. J. and Spencer, J. P. E. (2007) Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavanones in cortical neurons. Journal of Neurochemistry, 103 (4). pp. 1355-1367. ISSN 0022-3042 doi: https://doi.org/10.1111/j.1471-4159.2007.04841.x

Vauzour, D., Vafeiadou, K., Corona, G., Pollard, S. E., Tzounis, X. and Spencer, J. P. E. (2007) Champagne wine polyphenols protect primary cortical neurons against peroxynitrite-induced injury. Journal of Agricultural and Food Chemistry, 55 (8). pp. 2854-2860. ISSN 0021-8561 doi: https://doi.org/10.1021/jf063304z

Vauzour, D., Vafeiadou, K., Rice-Evans, C., Cadenas, E. and Spencer, J. P. E. (2007) Inhibition of cellular proliferation by the genistein metabolite 5,7,3',4'-tetrahydroxyisoflavone is mediated by DNA damage and activation of the ATR signalling pathway. Archives of Biochemistry and Biophysics, 468 (2). pp. 159-166. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2007.09.021

Corona, G., Deiana, M., Incani, A., Vauzour, D., Dessi, M.A. and Spencer, J.P.E. (2007) Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects. Biochemical and Biophysical Research Communications, 362 (3). pp. 606-611. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2007.08.049

Vauzour, D., Vafeiadou, K. and Spencer, J. P. E. (2007) Inhibition of the formation of the neurotoxin 5-S-cysteinyl-dopamine by polyphenols. Biochemical and Biophysical Research Communications, 362 (2). pp. 340-346. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2007.07.153

Vafeiadou, K., Vauzour, D. and Spencer, J. P. E. (2007) Neuroinflammation and its modulation by flavonoids. Endocrine, Metabolic & Immune Disorders - Drug Targets, 7 (3). pp. 211-224. ISSN 2212-3873

Hernandez-Montes, E., Pollard, S.E., Vauzour, D., Jofre-Montseny, L., Rota, C., Rimbach, G., Weinberg, P.D. and Spencer, J.P.E. (2006) Activation of glutathione peroxidase via Nrf1 mediates genistein's protection against oxidative endothelial cell injury. Biochemical and Biophysical Research Communications, 346 (3). pp. 851-859. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2006.05.197

Nguyen, D.T., Hemandez-Montes, E., Vauzour, D., Schonthal, A.H., Rice-Evans, C., Cadenas, E. and Spencer, J.P.E. (2006) The intracellular genistein metabolite 5,7,3 ',4 '-tetrahydroxyisoflavone mediates G2-M cell cycle arrest in cancer cells via modulation of the p38 signaling pathway. Free Radical Biology and Medicine, 41 (8). pp. 1225-1239. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2006.06.026

Pollard, S.E., Kuhnle, G.G.C., Vauzour, D., Vafeiadou, K., Tzounis, X., Whiteman, M., Rice-Evans, C. and Spencer, J.P.E. (2006) The reaction of flavonoid metabolites with peroxynitrite. Biochemical and Biophysical Research Communications, 350 (4). pp. 960-968. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2006.09.131

Book or Report Section

Vauzour, D., Spilsbury, A., Vafeiadou, K., Rattray, M. and Spencer, J. (2012) Modulation of neuroinflammation by dietary flavonoids. In: Gemma, C. (ed.) Neuroinflammation: Pathogenesis, Mechanisms and Management. Nova, pp. 213-236. ISBN 9781619424623