Article

Arjmand, S. , Behzadi, M., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238, Ezzatabadipou, S. , Seifaddini, R. , Arjmand, S. and Shabani, M. (2018) A brain on a roller coaster: can the dopamine reward system act as a protagonist to subdue the ups and downs of bipolar disorder? The Neuroscientist, 24 (5). pp. 423-439. ISSN 1073-8584 doi: https://doi.org/10.1177/1073858417714226

Barrese, V., Stott, J. B., Figueiredo, H. B., Aubdool, A. A., Hobbs, A. J., Jepps, T. A., McNeish, A. and Greenwood, I. A. (2018) Angiotensin II promotes KV7.4 channels degradation through reduced interaction with HSP90 (heat shock protein 90). Hypertension, 71 (6). pp. 1091-1100. ISSN 1524-4563 doi: https://doi.org/10.1161/HYPERTENSIONAHA.118.11116

Bell, D. C. and Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522 (2018) Using automated patch clamp electrophysiology platforms in pain-related ion channel research: insights from industry and academia. British Journal of Pharmacology, 175 (12). pp. 2312-2321. ISSN 1476-5381 doi: https://doi.org/10.1111/bph.13916

Centeno, E. G. Z., Cimarosti, H. and Bithell, A. (2018) 2D versus 3D human induced pluripotent stem cell-derived cultures for neurodegenerative disease modelling. Molecular Neurodegeneration, 13 (1). 27. ISSN 1750-1326 doi: https://doi.org/10.1186/s13024-018-0258-4

Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627, Soubrane, C. H., Hounshell, J. A., Lin, H., Owenson, V., Rigby, M., Cox, P. J., Barker, B. S., Ottolini, M., Ince, S., Bauer, C. C., Perez-Reyes, E., Patel, M. K., Stevens, E. B. and Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 (2018) CACHD1 is an α2δ-like protein that modulates CaV3 voltage-gated calcium channel activity. The Journal of Neuroscience, 38 (4). pp. 9186-9201. ISSN 1529-2401 doi: https://doi.org/10.1523/JNEUROSCI.3572-15.2018

Ferrari, R., Kia, D. A., Tomkins, J. E., Hardy, J., Wood, N. W., Lovering, R. C., Lewis, P. A. and Manzoni, C. (2018) Stratification of candidate genes for Parkinson’s disease using weighted protein interaction network analysis. BMC Genomics, 19. 452. ISSN 1471-2164 doi: https://doi.org/10.1186/s12864-018-4804-9

Giacomina, R., Redaelli, V., Contiero, P., Fabiano, S., Tagliabue, G., Perego, P., Benussi, L., Bruni, A., Filippini, G., Farinotti, M., Giaccone, G., Buitatiotis, S., Manzoni, C., Ferrari, R. and Tagliavini, F. (2018) Tau mutations serve as a novel risk factor for cancer. Cancer Research, 78 (13). pp. 3731-3739. ISSN 0008-5472 doi: https://doi.org/10.1158/0008-5472.CAN-17-3175

Hackl, E., Darkwah, J., Smith, G. and Ermolina, I. (2018) Effect of arginine on the aggregation of protein in freeze-dried Formulations containing sugars and polyol: 1-formulation development. AAPS PharmSciTech, 19 (2). pp. 896-911. ISSN 1530-9932 doi: https://doi.org/10.1208/s12249-017-0884-0

Hackl, E., Darkwah, J., Smith, G. and Ermolina, I. (2018) Effect of arginine on the aggregation of protein in freeze-dried formulations containing sugars and polyol: II. BSA reconstitution and aggregation. AAPS PharmSciTech, 19 (7). pp. 2934-2947. ISSN 1530-9932 doi: https://doi.org/10.1208/s12249-018-1114-0

Hartlova, A., Herbst, S., Peltier, J., Rodgers, A., Bilkei-Gorzo, O., Fearns, A., Dill, B. D., Lee, H., Rowan, F., Cowley, S. A., Davies, P., Lewis, P. A., Ganley, I. G., Martinez, J., Alessi, D. R., Reith, A. D., Trost, M. and Gutierrez, M. G. (2018) LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages. The EMBO Journal, 37 (12). e98694. ISSN 0261-4189 doi: https://doi.org/10.15252/embj.201798694

Jammal, L., Whalley, B. and Barkai, E. (2018) Learning-induced modulation of the effect of neuroglial transmission onsynaptic plasticity. Journal of Neurophysiology, 119 (6). pp. 2373-2379. ISSN 0022-3077 doi: https://doi.org/10.1152/jn.00101.2018

Limbu, R., Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 and McNeish, A. J. (2018) Characterisation of the vasodilation effects of DHA and EPA, n-3 PUFAs (fish oils), in rat aorta and mesenteric resistance arteries. PLoS ONE, 13 (2). e0192484. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0192484

Maiarù, M. ORCID: https://orcid.org/0000-0003-0927-6567, Leese, C., Certo, M., Echeverria-Altuna, I., Mangione, A. S., Arsenault, J., Davletov, B. and Hunt, S. P. (2018) Selective neuronal silencing using synthetic botulinum molecules alleviates chronic pain in mice. Science Translational Medicine, 10 (450). eaar7384. ISSN 1946-6234 doi: https://doi.org/10.1126/scitranslmed.aar7384

Maiarù, M. ORCID: https://orcid.org/0000-0003-0927-6567, Morgan, O. B., Mao, T., Breitsamer, M., Bamber, H., Pöhlmann, M., Schmidt, M. V., Winter, G., Hausch, F. and Géranton, S. M. (2018) The stress regulator FKBP51: a novel and promising druggable target for the treatment of persistent pain states across sexes. Pain, 159 (7). pp. 1224-1234. ISSN 1872-6623 doi: https://doi.org/10.1097/j.pain.0000000000001204

Mamais, A., Manzoni, C., Nazish, I., Arber, C., Sonustun, B., Wray, S., Warner, T. T., Cookson, M. R., Lewis, P. A. and Bandopadhyay, R. (2018) Analysis of macroautophagy related proteins in G2019S LRRK2 Parkinson's disease brains with Lewy body pathology. Brain Research, 1701. pp. 75-84. ISSN 0006-8993 doi: https://doi.org/10.1016/j.brainres.2018.07.023

Manzoni, C., Kia, D. A., Vandrovcova, J., Hardy, J., Wood, N. W., Lewis, P. A. and Ferrari, R. (2018) Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences. Briefings In Bioinformatics, 19 (2). pp. 286-302. ISSN 1467-5463 doi: https://doi.org/10.1093/bib/bbw114

Manzoni, C., Mamais, A., Dihanich, S., Soutar, M. P. M., Plun-Favreau, H., Bandopadhyay, R., Abeti, R., Giunti, P., Hardy, J., Cookson, M. R., Tooze, S. A. and Lewis, P. A. (2018) mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition. Bioscience Reports, 38 (2). BSR20171669. ISSN 0144-8463 doi: https://doi.org/10.1042/BSR20171669

McQuaid, K., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Cardin, D. J. and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 (2018) X-ray crystal structures show DNA stacking advantage of terminal nitrile substitution in Ru-dppz complexes. Chemistry- A European Journal, 24 (59). pp. 15859-15867. ISSN 1521-3765 doi: https://doi.org/10.1002/chem.201803021

Palombo, F., Masia, F., Mattana, S., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Borri, P., Langbein, W. and Fioretto, D. (2018) Hyperspectral analysis applied to micro-Brillouin maps of amyloid-beta plaques in Alzheimer’s disease brains. Analysis, 143 (24). pp. 6095-6102. ISSN 1467-8284 doi: https://doi.org/10.1039/C8AN01291A

Palombo, F., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Jeynes, C., Mattana, S., Swift, I., Nallala, J., Hancock, J., Brown, J. T., Randall, A. D. and Stone, N. (2018) Detection of Aβ plaque-associated astrogliosis in Alzheimer’s disease brain by spectroscopic imaging and immunohistochemistry. Analyst, 143 (4). pp. 850-857. ISSN 0003-2654 doi: https://doi.org/10.1039/c7an01747b

Price, A., Manzoni, C., Cookson, M. R. and Lewis, P. A. (2018) The LRRK2 signalling system. Cell and Tissue Research, 373 (1). pp. 39-50. ISSN 0302-766X doi: https://doi.org/10.1007/s00441-017-2759-9

Ravishankar, D., Salamah, M., Akimbaev, A., Williams, H. F., Albadawi, D. A. I., Vaiyapuri, R., Greco, F., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2018) Impact of specific functional groups in flavonoids on the modulation of platelet activation. Scientific Reports, 8. 9528. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-018-27809-z

Roosterman, D., Meyerhof, W. and Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 (2018) Proton transport chains in glucose metabolism: mind the proton. Frontiers in Neuroscience, 12. 404. ISSN 1662-453X doi: https://doi.org/10.3389/fnins.2018.00404

Salamah, M. F., Ravishankar, D., Kodji, X., Moraes, L. A., Williams, H. F., Vallance, T. M., Albadawi, D. A., Vaiyapuri, R., Watson, K. ORCID: https://orcid.org/0000-0002-9987-8539, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Brain, S. D., Perretti, M. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2018) The endogenous antimicrobial cathelicidin LL37 induces platelet activation and augments thrombus formation. Blood Advances, 2 (21). pp. 2973-2985. ISSN 2473-9529 doi: https://doi.org/10.1182/bloodadvances.2018021758

Sheard, J., Ramasamy, T. S. and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2018) From fibroblasts to medicinal signalling cells: a paradigm shift in translational stem cell research. Drug Target Review, 2018 (2). pp. 42-44. ISSN 2059-1349

Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Cotton, M., Goodall, O., Harrison, G., Jeynes, C., Palombo, F., Tomkow, J., Tomkow, T. and Wedgwood, K. (2018) ‘Of Mice and Dementia’: A filmed conversation on the use of animals in dementia research. Dementia, 17 (8). pp. 1055-1063. ISSN 1741-2684 doi: https://doi.org/10.1177/1471301218789560

Thei, L., Imm, J., Kaisis, E., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522 and Dallas, T. L. (2018) Microglia in Alzheimer's disease: a role for ion channels. Frontiers in Neuroscience, 12. 676. ISSN 1662-453X doi: https://doi.org/10.3389/fnins.2018.00676

Thei, L., Rocha-Ferreira, E., Peebles, D., Raivich, G. and Hristova, M. (2018) Extracellular signal-regulated kinase 2 has duality in function between neuronal and astrocyte expression following neonatal hypoxic-ischaemic cerebral injury. The Journal of Physiology, 596 (23). pp. 6043-6062. ISSN 0022-3751 doi: https://doi.org/10.1113/jp275649

Tomkins, J. E., Dihanich, S., Beilina, A., Ferrari, R., Ilacqua, N., Cookson, M. R., Lewis, P. A. and Manzoni, C. (2018) Comparative protein interaction network analysis identifies shared and distinct functions for the human ROCO proteins. Proteomics, 18 (10). 1700444. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.201700444

Williams, H. F., Hayter, P., Ravishankar, D., Baines, A., Layfield, H. J., Croucher, L., Wark, C., Bicknell, A. B., Trim, S. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2018) Impact of Naja nigricollis venom on the production of methaemoglobin. Toxins, 10 (12). 539. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins10120539

Zakaria, N., Yusoff, N. M., Zakaria, Z., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Yahaya, B. H. (2018) Inhibition of NF-κB signalling reduces the stemness characteristics of lung cancer stem cells. Frontiers in Oncology, 8. 166. ISSN 2234-943X doi: https://doi.org/10.3389/fonc.2018.00166

Zeuner, M.-T., Didenko, N. N., Humphries, D., Stergiadis, S. ORCID: https://orcid.org/0000-0002-7293-182X, Morash, T. M., Patel, K., Grimm, W.-D. and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2018) Isolation and characterisation of neural crest-derived stem cells from adult ovine palatal tissue. Frontiers in Cell and Developmental Biology, 6. 39. ISSN 2296-634X doi: https://doi.org/10.3389/fcell.2018.00039

Book or Report Section

Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 (2018) CGRP receptor signalling pathways. In: Handbook of Experimental Pharmacology. Springer. doi: https://doi.org/10.1007/164_2018_130

Book

Stevens, E. B. and Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238, eds. (2018) Recent advances in targeting ion channels to treat chronic pain. British Journal of Pharmacology, 175 (12). Wiley, pp. 2133-2137. doi: https://doi.org/10.1111/bph.14215