Number of items: 52.
Article
Cheeseman, J., Kuhnle, G.
ORCID: https://orcid.org/0000-0002-8081-8931, Spencer, D. I.R. and Osborn, H.
(2020)
Assays for the identification and quantification of sialic acids: challenges, opportunities and future perspectives.
Bioorganic & Medicinal Chemistry.
ISSN 0968-0896
doi: https://doi.org/10.1016/j.bmc.2020.115882
(In Press)
Dönmez, S. İ., Needs, S. H.
ORCID: https://orcid.org/0000-0003-3407-9637, Osborn, H. M. I. and Edwards, A. D.
ORCID: https://orcid.org/0000-0003-2369-989X
(2020)
Label-free smartphone quantitation of bacteria by darkfield imaging of light scattering in fluoropolymer micro capillary film allows portable detection of bacteriophage lysis.
Sensors and Actuators B: Chemical, 323.
p. 128645.
ISSN 0925-4005
doi: https://doi.org/10.1016/j.snb.2020.128645
Khater, M., Greco, F. and Osborn, H. M. I.
(2020)
Antiangiogenic activity of flavonoids: a systematic review and meta-analysis.
Molecules, 25 (20).
4712.
ISSN 1420-3049
doi: https://doi.org/10.3390/molecules25204712
Needs, S., Donmez, S. I., Bull, S., McQuaid, C., Osborn, H. M. I. and Edwards, A.
ORCID: https://orcid.org/0000-0003-2369-989X
(2020)
Challenges in microfluidic and point-of-care phenotypic antimicrobial resistance tests.
Frontiers in Mechanical Engineering, 6.
ISSN 2297-3079
doi: https://doi.org/10.3389/fmech.2020.00073
Natfji, A. A., Nikitin, D. O., Semina, I. I., Moustafine, R. I., Khutoryanskiy, V. V., Lin, H., Stephens, G. J., Watson, K. A., Osborn, H. M. I. and Greco, F.
(2020)
Conjugation of haloperidol to PEG allows peripheral localisation of haloperidol and eliminates CNS extrapyramidal effects.
Journal of Controlled Release, 322.
pp. 227-235.
ISSN 0168-3659
doi: https://doi.org/10.1016/j.jconrel.2020.02.037
Khater, M., Ravishankar, D., Greco, F. and Osborn, H.
(2019)
Metal complexes of flavonoids: their synthesis, characterization, and enhanced anti-oxidant and anti-cancer activities.
Future Medicinal Chemistry, 11 (21).
ISSN 1756-8927
doi: https://doi.org/10.4155/fmc-2019-0237
Vallance, T. M., Ravishankar, D., Albadawi, D. A. I., Osborn, H. M. I. and Vaiyapuri, S.
(2019)
Synthetic flavonoids as novel modulators of platelet function and thrombosis.
International Journal of Molecular Sciences, 20 (12).
e3106.
ISSN 1422-0067
doi: https://doi.org/10.3390/ijms20123106
Howse, G. L., Bovill, R. A., Stephens, P. J. and Osborn, H. M. I.
(2019)
Synthesis and antibacterial profiles of targeted triclosan derivatives.
European Journal of Medicinal Chemistry, 162.
pp. 51-58.
ISSN 0223-5234
doi: https://doi.org/10.1016/j.ejmech.2018.10.053
Ravishankar, D., Salamah, M., Akimbaev, A., Williams, H. F., Albadawi, D. A. I., Vaiyapuri, R., Greco, F., Osborn, H. M. I. and Vaiyapuri, S.
(2018)
Impact of specific functional groups in flavonoids on the modulation of platelet activation.
Scientific Reports, 8.
9528.
ISSN 2045-2322
doi: https://doi.org/10.1038/s41598-018-27809-z
Brown, G. D., Bauer, J., Osborn, H. M. I. and Kuemmerle, R.
(2018)
A solution NMR approach to determine the chemical structures of carbohydrates using the hydroxyl groups as starting points.
ACS Omega, 3 (12).
pp. 17957-17975.
ISSN 2470-1343
doi: https://doi.org/10.1021/acsomega.8b02136
Natfji, A. A., Ravishankar, D., Osborn, H. M. I. and Greco, F.
(2017)
Parameters affecting the enhanced permeability and retention effect: the need for patient selection.
Journal of Pharmaceutical Sciences, 106 (11).
pp. 3179-3187.
ISSN 0022-3549
doi: https://doi.org/10.1016/j.xphs.2017.06.019
Natfji, A. A., Osborn, H. M. I. and Greco, F.
(2017)
Feasibility of polymer-drug conjugates for non-cancer applications.
Current Opinion in Colloid & Interface Science, 31.
pp. 51-66.
ISSN 1359-0294
doi: https://doi.org/10.1016/j.cocis.2017.07.004
Thomson, R. I., Gardner, R. A., Strohfeldt, K., Fernandes, D. L., Stafford, G. P., Spencer, D. I. R. and Osborn, H. M. I.
(2017)
Analysis of three epoetin alpha products by LC and LC-MS indicates differences in glycosylation critical quality attributes, including sialic acid content.
Analytical Chemistry, 89 (12).
pp. 6455-6462.
ISSN 0003-2700
doi: https://doi.org/10.1021/acs.analchem.7b00353
Ravishankar, D., Salamah, M., Attina, A., Pothi, R., Vallance, T. M., Javed, M., Williams, H. F., Alzahrani, E. M. S., Kabova, E., Vaiyapuri, R., Shankland, K., Gibbins, J., Strohfeldt, K., Greco, F., Osborn, H. M. I. and Vaiyapuri, S.
(2017)
Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacy.
Scientific Reports, 7.
5738.
ISSN 2045-2322
doi: https://doi.org/10.1038/s41598-017-05936-3
Heath, F., Newman, A., Clementi, C., Pasut, G., Lin, H., Stephens, G. J., Whalley, B. J., Osborn, H. M. I. and Greco, F.
(2016)
A novel PEG–haloperidol conjugate with a non-degradable linker shows the feasibility of using polymer–drug conjugates in a non-prodrug fashion.
Polymer Chemistry, 7 (47).
pp. 7204-7210.
ISSN 1759-9954
doi: https://doi.org/10.1039/c6py01418f
Ravishankar, D., Corona, G., Hogan, S. M., Spencer, J. P. E., Greco, F. and Osborn, H. M. I.
(2016)
Thioflavones as novel neuroprotective agents.
Bioorganic & Medicinal Chemistry, 24 (21).
pp. 5513-5520.
ISSN 0968-0896
doi: https://doi.org/10.1016/j.bmc.2016.09.006
Bovill, R., Evans, P. G., Howse, G. L. and Osborn, H. M. I.
(2016)
Synthesis and biological analysis of novel glycoside derivatives of L-AEP, as targeted antibacterial agents.
Bioorganic & Medicinal Chemistry Letters, 26 (15).
pp. 3774-3779.
ISSN 0960-894X
doi: https://doi.org/10.1016/j.bmcl.2016.05.052
Ravishankar, D., Watson, K. A., Greco, F. and Osborn, H. M. I.
(2016)
Novel synthesised flavone derivatives provide significant insight into the structural features required for enhanced anti-proliferative activity.
RSC Advances, 6 (69).
pp. 64544-64556.
ISSN 2046-2069
doi: https://doi.org/10.1039/C6RA11041J
Parshotam, J. P., Brazier, J. A., Bovill, R. and Osborn, H. M. I.
(2016)
An efficient and rapid microwave-assisted synthesis of 1-acetyl-1H-indol-3-YL acetates.
Current Microwave Chemistry, 3 (3).
pp. 247-257.
ISSN 2213-3364
doi: https://doi.org/10.2174/2213335603666160108001556
Bauer, J. and Osborn, H. M. I.
(2015)
Sialic acids in biological and therapeutic processes: opportunities and challenges.
Future Medicinal Chemistry, 7 (16).
pp. 2285-2299.
ISSN 1756-8927
doi: https://doi.org/10.4155/fmc.15.135
Ravishankar, D., Watson, K. A., Boateng, S. Y., Green, R. J., Greco, F. and Osborn, H. M.I.
(2015)
Exploring quercetin and luteolin derivatives as antiangiogenic agents.
European Journal of Medicinal Chemistry, 97.
pp. 259-274.
ISSN 0223-5234
doi: https://doi.org/10.1016/j.ejmech.2015.04.056
Rajora, A. K., Ravishankar, D., Osborn, H. M.I. and Greco, F.
(2014)
Impact of the enhanced permeability and retention (EPR) effect and cathepsins levels on the activity of polymer-drug conjugates.
Polymers, 6 (8).
pp. 2186-2220.
ISSN 2073-4360
doi: https://doi.org/10.3390/polym6082186
Ravishankar, D., Rajora, A., Greco, F. and Osborn, H.
(2013)
Flavonoids as prospective compounds for anti-cancer therapy.
International Journal of Biochemistry and Cell Biology, 45 (12).
pp. 2821-2831.
ISSN 1878-5875
doi: https://doi.org/10.1016/j.biocel.2013.10.004
Jarvis, A. N., McClaren, A. B., Osborn, H. M. I. and Sweeney, J.
(2013)
Preparation and ring-opening reactions of N-diphenylphosphinyl vinyl aziridines.
Beilstein Journal of Organic Chemistry, 9.
pp. 852-859.
ISSN 1860-5397
doi: https://doi.org/10.3762/bjoc.9.98
Burland, P. A., Osborn, H. M. I. and Turkson, A.
(2011)
Synthesis and glycosidase inhibitory profiles of functionalised morpholines and oxazepanes.
Bioorganic & Medicinal Chemistry, 19 (18).
pp. 5679-5692.
ISSN 0968-0896
doi: https://doi.org/10.1016/j.bmc.2011.07.019
Fante, C., Eldar-Boock, A., Satchi-Fainaro, R., Osborn, H. M. I. and Greco, F.
(2011)
Synthesis and biological evaluation of a polyglutamic acid-dopamine conjugate: a new antiangiogenic agent.
Journal of Medicinal Chemistry, 54 (14).
pp. 5255-5259.
ISSN 0022-2623
doi: https://doi.org/10.1021/jm200382r
Benning, R. K., Osborn, H. M. I. and Turkson, A.
(2011)
Regioselective Beckmann rearrangements of furanoside and pyranoside-derived oximes.
Tetrahedron: Asymmetry, 22 (1).
pp. 109-116.
ISSN 0957-4166
doi: https://doi.org/10.1016/j.tetasy.2010.11.031
Burland, P. A., Coisson, D. and Osborn, H. M. I.
(2010)
Rapid synthesis of carbohydrate derivatives, including mimetics of c-linked disaccharides and c-Linked aza disaccharides, using the Hetero-Diels−Alder Reaction.
Journal of Organic Chemistry, 75 (21).
pp. 7210-7218.
ISSN 0022-3263
doi: https://doi.org/10.1021/jo101219w
Carlescu, I., Osborn, H. M.I., Desbrieres, J., Scutaru, D. and Popa, M.
(2010)
Synthesis of poly(aspartimide)-based bio-glycoconjugates.
Carbohydrate Research, 345 (1).
pp. 33-40.
ISSN 0008-6215
doi: https://doi.org/10.1016/j.carres.2009.08.034
Osborn, H. M. I. and Turkson, A.
(2009)
Synthesis and NMR spectroscopic analysis of 3-nitro-pyranoside, 3-nitro-septanoside and 4-nitro-septanoside derivatives by condensation of the anion of nitromethane with glycoside.
Tetrahedron Asymmetry, 20 (18).
pp. 2162-2166.
ISSN 0957-4166
doi: https://doi.org/10.1016/j.tetasy.2009.08.004
Jawaid, S., Khan, T. H., Osborn, H. M. I. and Williams, N. O. A.
(2009)
Tyrosinase activated melanoma prodrugs.
Anti-cancer agents in medicinal chemistry, 9 (7).
pp. 717-727.
ISSN 1871-5206
Bonjoch, J., Drew, M. G.B., Gonzalez, A., Greco, F., Jawaid, S., Osborn, H. M. I., Williams, N. A.O. and Yaqoob, P.
(2008)
Synthesis and evaluation of novel boron-containing complexes of potential use for the selective treatment of malignant melanoma.
Journal of Medicinal Chemistry, 51 (20).
pp. 6604-6608.
ISSN 0022-2623
doi: https://doi.org/10.1021/jm8007745
Ellis, D., Norman, S. E. and Osborn, H. M. I.
(2008)
Synthesis of S-linked carbohydrate analogues via a Ferrier reaction.
Tetrahedron, 64 (12).
pp. 2832-2854.
ISSN 0040-4020
doi: https://doi.org/10.1016/j.tet.2008.01.042
Owen, R.E., Yamada, E., Thompson, C.I., Phillipson, L.J., Thompson, C., Taylor, E., Zambon, M., Osborn, H.M.I., Barclay, W.S. and Borrow, P.
(2007)
Alterations in receptor binding properties of recent human influenza H3N2 viruses are associated with reduced natural killer cell lysis of infected cells.
Journal of Virology, 81 (20).
pp. 11170-11178.
ISSN 0022-538X
doi: https://doi.org/10.1128/jvi.01217-07
Jawaid, S., Osborn, H.M.I. and Williams, N.A.O.
(2007)
Fighting skin cancer with prodrugs.
Education in Chemistry, 44 (3).
pp. 77-81.
ISSN 0013-1350
Liu, Y., Feizi, T., Carnpanero-Rhodes, M.A., Childs, R.A., Zhang, Y.N., Muiioy, B., Evans, P.G., Osborn, H.M.I., Otto, D., Crocker, P.R. and Chai, W.C.
(2007)
Neoglycolipid probes prepared via oxime ligation for microarray analysis of oligosaccharide-protein interactions.
Chemistry & Biology, 14 (7).
pp. 847-859.
ISSN 1074-5521
doi: https://doi.org/10.1016/j.chembiol.2007.06.009
Barclay, W.S., Jones, I.M., Osborn, H.M.I., Phillipson, L., Ren, J.Y., Talevera, G.A. and Thompson, C.I.
(2007)
Probing the receptor interactions of an H5 avian influenza virus using a baculovirus expression system and functionalised poly(acrylic acid) ligands.
Bioorganic & Medicinal Chemistry, 15 (12).
pp. 4038-4047.
ISSN 0968-0896
doi: https://doi.org/10.1016/j.bmc.2007.03.085
Chai, W., Piskarev, V.E., Mulloy, B., Liu, Y., Evans, P.G., Osborn, H.M.I. and Lawson, A.M.
(2006)
Analysis of chain and blood group type and branching pattern of sialylated oligosaccharides by negative ion electrospray tandem mass spectrometry.
Analytical Chemistry, 78 (5).
pp. 1581-1592.
ISSN 0003-2700
doi: https://doi.org/10.1021/ac051606e
Brome, V.A., Harwood, L.M. and Osborn, H.M.I.
(2006)
Preparation of enantiopure long chain threo-2-amino-3-hydroxyesters via chiral morpholinone-derived azomethine ylids.
Canadian Journal of Chemistry-Revue Canadienne De Chimie, 84 (10).
pp. 1448-1455.
ISSN 0008-4042
doi: https://doi.org/10.1139/v06-121
Osborn, H.M.I.
(2005)
Development of new methodologies for entry to targets of therapeutic interest.
Synlett (17).
pp. 2571-2586.
ISSN 0936-5214
doi: https://doi.org/10.1055/s-2005-917076
Knaggs, S., Malkin, H., Osborn, H.M.I., Williams, N.A.O. and Yaqoob, P.
(2005)
New prodrugs derived from 6-aminodopamine and 4-aminophenol as candidates for melanocyte-directed enzyme prodrug therapy (MDEPT).
Organic & Biomolecular Chemistry, 3 (21).
pp. 4002-4010.
ISSN 1477-0520
doi: https://doi.org/10.1039/b506404j
Osborn, H.M.I., Meo, P. and Nijara, R.K.
(2005)
A new entry to 4,6-O-benzylidene glucal from phenyl 1-seleno-alpha-D-mannopyranoside.
Tetrahedron-Asymmetry, 16 (11).
pp. 1935-1937.
ISSN 0957-4166
doi: https://doi.org/10.1016/j.tetasy.2005.05.004
Osborn, H.M.I. and Coisson, D.
(2004)
Application of the asymmetric hetero Diels-Alder reaction for synthesising carbohydrate derivatives and glycosidase inhibitors.
Mini-Reviews in Organic Chemistry, 1 (1).
pp. 41-54.
ISSN 1570-193X
doi: https://doi.org/10.2174/1570193043488953
Osborn, H.M.I., Evans, P.G., Gemmell, N. and Osborne, S.D.
(2004)
Carbohydrate-based therapeutics.
Journal of Pharmacy and Pharmacology, 56 (6).
pp. 691-702.
ISSN 0022-3573
doi: https://doi.org/10.1211/0022357023619
Osborn, H.M.I. and Williams, N.A.O.
(2004)
Development of tyrosinase labile protecting groups for amines.
Organic Letters, 6 (18).
pp. 3111-3113.
ISSN 1523-7060
doi: https://doi.org/10.1021/ol040042i
Clark, S.M. and Osborn, H.M.I.
(2004)
Synthetic entry to functionalised morpholines and [1,4]-oxazepanes via reductive amination reactions of carbohydrate derived dialdehydes.
Tetrahedron-Asymmetry, 15 (22).
pp. 3643-3652.
ISSN 0957-4166
doi: https://doi.org/10.1016/j.tetasy.2004.10.002
Hayes, W., Osborn, H.M.I., Osborne, S.D., Rastall, R.A. and Romagnoli, B.
(2003)
One-pot synthesis of multivalent arrays of mannose mono- and disaccharides.
Tetrahedron, 59 (40).
pp. 7983-7996.
ISSN 0040-4020
doi: https://doi.org/10.1016/j.tet.2003.08.011
Gemmell, N., Meo, P. and Osborn, H.M.I.
(2003)
Stereoselective entry to beta-linked C-disaccharides using a carbon-Ferrier reaction.
Organic Letters, 5 (10).
pp. 1649-1652.
ISSN 1523-7060
doi: https://doi.org/10.1021/ol030023t
Jordan, A.M., Osborn, H.M.I., Stafford, P.M., Tzortzis, G. and Rastall, R.A.
(2003)
Synthesis of unsaturated aminopyranosides as possible transition state mimics for glycosidases.
Journal of Carbohydrate Chemistry, 22 (7-8).
pp. 705-717.
ISSN 0732-8303
doi: https://doi.org/10.1081/car-120026469
Book or Report Section
Osborn, H.M.I. and Turkson, A.
(2009)
Sugars as pharmaceuticals.
In: Gabius, H.-J. (ed.)
The sugar code: fundamentals of glycosciences.
Wiley-VCH, Weinheim, pp. 469-485.
ISBN 9783527320899
Osborn, H.M.I., Evans, P.G. and Bezouska, K.
(2008)
Biomedicine of monosaccharides.
In: Fraser-Reid, B.O., Tatsuta, K., Thiem, J., Coté, G.L., Flitsch, S., Ito, Y., Kondo, H., Nishimura, S.-i. and Yu, B. (eds.)
Glycoscience: chemistry and chemical biology.
Springer , Berlin, pp. 2399-2444.
ISBN 9783540304296
Book
Osborn, H.M.I.
(2003)
Carbohydrates.
Best synthetic methods.
Academic Press, Oxford.
ISBN 9780123120854
This list was generated on Mon Jan 25 05:33:30 2021 UTC.