Accessibility navigation


Items where Author is "Osborn, Professor Helen"

Up a level
Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Group by: Item Type | No Grouping
Number of items: 32.

Article

Rajora, A. K., Ravishankar, D., Osborn, H. M.I. and Greco, F. (2014) Impact of the enhanced permeability and retention (EPR) effect and cathepsins levels on the activity of polymer-drug conjugates. Polymers, 6 (8). pp. 2186-2220. ISSN 2073-4360 doi: 10.3390/polym6082186

Ravishankar, D., Rajora, A., Greco, F. and Osborn, H. (2013) Flavonoids as prospective compounds for anti-cancer therapy. International Journal of Biochemistry and Cell Biology, 45 (12). pp. 2821-2831. ISSN 1878-5875 doi: 10.1016/j.biocel.2013.10.004

Jarvis, A. N., McClaren, A. B., Osborn, H. M. I. and Sweeney, J. (2013) Preparation and ring-opening reactions of N-diphenylphosphinyl vinyl aziridines. Beilstein Journal of Organic Chemistry, 9. pp. 852-859. ISSN 1860-5397 doi: 10.3762/bjoc.9.98

Burland, P. A., Osborn, H. M. I. and Turkson, A. (2011) Synthesis and glycosidase inhibitory profiles of functionalised morpholines and oxazepanes. Bioorganic & Medicinal Chemistry, 19 (18). pp. 5679-5692. ISSN 0968-0896 doi: 10.1016/j.bmc.2011.07.019

Fante, C., Eldar-Boock, A., Satchi-Fainaro, R., Osborn, H. M. I. and Greco, F. (2011) Synthesis and biological evaluation of a polyglutamic acid-dopamine conjugate: a new antiangiogenic agent. Journal of Medicinal Chemistry, 54 (14). pp. 5255-5259. ISSN 0022-2623 doi: 10.1021/jm200382r

Benning, R. K., Osborn, H. M. I. and Turkson, A. (2011) Regioselective Beckmann rearrangements of furanoside and pyranoside-derived oximes. Tetrahedron: Asymmetry, 22 (1). pp. 109-116. ISSN 0957-4166 doi: 10.1016/j.tetasy.2010.11.031

Burland, P. A., Coisson, D. and Osborn, H. M. I. (2010) Rapid synthesis of carbohydrate derivatives, including mimetics of c-linked disaccharides and c-Linked aza disaccharides, using the Hetero-Diels−Alder Reaction. Journal of Organic Chemistry, 75 (21). pp. 7210-7218. ISSN 0022-3263 doi: 10.1021/jo101219w

Carlescu, I., Osborn, H. M.I., Desbrieres, J., Scutaru, D. and Popa, M. (2010) Synthesis of poly(aspartimide)-based bio-glycoconjugates. Carbohydrate Research, 345 (1). pp. 33-40. ISSN 0008-6215 doi: 10.1016/j.carres.2009.08.034

Osborn, H. M. I. and Turkson, A. (2009) Synthesis and NMR spectroscopic analysis of 3-nitro-pyranoside, 3-nitro-septanoside and 4-nitro-septanoside derivatives by condensation of the anion of nitromethane with glycoside. Tetrahedron Asymmetry, 20 (18). pp. 2162-2166. ISSN 0957-4166 doi: 10.1016/j.tetasy.2009.08.004

Jawaid, S., Khan, T. H., Osborn, H. M. I. and Williams, N. O. A. (2009) Tyrosinase activated melanoma prodrugs. Anti-cancer agents in medicinal chemistry, 9 (7). pp. 717-727. ISSN 1871-5206

Bonjoch, J., Drew, M. G.B., Gonzalez, A., Greco, F., Jawaid, S., Osborn, H. M. I., Williams, N. A.O. and Yaqoob, P. (2008) Synthesis and evaluation of novel boron-containing complexes of potential use for the selective treatment of malignant melanoma. Journal of Medicinal Chemistry, 51 (20). pp. 6604-6608. ISSN 0022-2623 doi: 10.1021/jm8007745

Ellis, D., Norman, S. E. and Osborn, H. M. I. (2008) Synthesis of S-linked carbohydrate analogues via a Ferrier reaction. Tetrahedron, 64 (12). pp. 2832-2854. ISSN 0040-4020 doi: 10.1016/j.tet.2008.01.042

Owen, R.E., Yamada, E., Thompson, C.I., Phillipson, L.J., Thompson, C., Taylor, E., Zambon, M., Osborn, H.M.I., Barclay, W.S. and Borrow, P. (2007) Alterations in receptor binding properties of recent human influenza H3N2 viruses are associated with reduced natural killer cell lysis of infected cells. Journal of Virology, 81 (20). pp. 11170-11178. ISSN 0022-538X doi: 10.1128/jvi.01217-07

Jawaid, S., Osborn, H.M.I. and Williams, N.A.O. (2007) Fighting skin cancer with prodrugs. Education in Chemistry, 44 (3). pp. 77-81. ISSN 0013-1350

Liu, Y., Feizi, T., Carnpanero-Rhodes, M.A., Childs, R.A., Zhang, Y.N., Muiioy, B., Evans, P.G., Osborn, H.M.I., Otto, D., Crocker, P.R. and Chai, W.C. (2007) Neoglycolipid probes prepared via oxime ligation for microarray analysis of oligosaccharide-protein interactions. Chemistry & Biology, 14 (7). pp. 847-859. ISSN 1074-5521 doi: 10.1016/j.chembiol.2007.06.009

Barclay, W.S., Jones, I.M., Osborn, H.M.I., Phillipson, L., Ren, J.Y., Talevera, G.A. and Thompson, C.I. (2007) Probing the receptor interactions of an H5 avian influenza virus using a baculovirus expression system and functionalised poly(acrylic acid) ligands. Bioorganic & Medicinal Chemistry, 15 (12). pp. 4038-4047. ISSN 0968-0896 doi: 10.1016/j.bmc.2007.03.085

Chai, W., Piskarev, V.E., Mulloy, B., Liu, Y., Evans, P.G., Osborn, H.M.I. and Lawson, A.M. (2006) Analysis of chain and blood group type and branching pattern of sialylated oligosaccharides by negative ion electrospray tandem mass spectrometry. Analytical Chemistry, 78 (5). pp. 1581-1592. ISSN 0003-2700 doi: 10.1021/ac051606e

Brome, V.A., Harwood, L.M. and Osborn, H.M.I. (2006) Preparation of enantiopure long chain threo-2-amino-3-hydroxyesters via chiral morpholinone-derived azomethine ylids. Canadian Journal of Chemistry-Revue Canadienne De Chimie, 84 (10). pp. 1448-1455. ISSN 0008-4042 doi: 10.1139/v06-121

Osborn, H.M.I. (2005) Development of new methodologies for entry to targets of therapeutic interest. Synlett (17). pp. 2571-2586. ISSN 0936-5214 doi: 10.1055/s-2005-917076

Knaggs, S., Malkin, H., Osborn, H.M.I., Williams, N.A.O. and Yaqoob, P. (2005) New prodrugs derived from 6-aminodopamine and 4-aminophenol as candidates for melanocyte-directed enzyme prodrug therapy (MDEPT). Organic & Biomolecular Chemistry, 3 (21). pp. 4002-4010. ISSN 1477-0520 doi: 10.1039/b506404j

Osborn, H.M.I., Meo, P. and Nijara, R.K. (2005) A new entry to 4,6-O-benzylidene glucal from phenyl 1-seleno-alpha-D-mannopyranoside. Tetrahedron-Asymmetry, 16 (11). pp. 1935-1937. ISSN 0957-4166 doi: 10.1016/j.tetasy.2005.05.004

Osborn, H.M.I. and Coisson, D. (2004) Application of the asymmetric hetero Diels-Alder reaction for synthesising carbohydrate derivatives and glycosidase inhibitors. Mini-Reviews in Organic Chemistry, 1 (1). pp. 41-54. ISSN 1570-193X doi: 10.2174/1570193043488953

Osborn, H.M.I., Evans, P.G., Gemmell, N. and Osborne, S.D. (2004) Carbohydrate-based therapeutics. Journal of Pharmacy and Pharmacology, 56 (6). pp. 691-702. ISSN 0022-3573 doi: 10.1211/0022357023619

Osborn, H.M.I. and Williams, N.A.O. (2004) Development of tyrosinase labile protecting groups for amines. Organic Letters, 6 (18). pp. 3111-3113. ISSN 1523-7060 doi: 10.1021/ol040042i

Clark, S.M. and Osborn, H.M.I. (2004) Synthetic entry to functionalised morpholines and [1,4]-oxazepanes via reductive amination reactions of carbohydrate derived dialdehydes. Tetrahedron-Asymmetry, 15 (22). pp. 3643-3652. ISSN 0957-4166 doi: 10.1016/j.tetasy.2004.10.002

Osborn, H.M., Brown, H., Adams, J.B. and Ledward, D.A. (2003) High temperature reduction of metmyoglobin in aqueous muscle extracts. Meat Science, 65 (1). pp. 631-637. ISSN 0309-1740 doi: 10.1016/s0309-1740(02)00258-9

Hayes, W., Osborn, H.M.I., Osborne, S.D., Rastall, R.A. and Romagnoli, B. (2003) One-pot synthesis of multivalent arrays of mannose mono- and disaccharides. Tetrahedron, 59 (40). pp. 7983-7996. ISSN 0040-4020 doi: 10.1016/j.tet.2003.08.011

Gemmell, N., Meo, P. and Osborn, H.M.I. (2003) Stereoselective entry to beta-linked C-disaccharides using a carbon-Ferrier reaction. Organic Letters, 5 (10). pp. 1649-1652. ISSN 1523-7060 doi: 10.1021/ol030023t

Jordan, A.M., Osborn, H.M.I., Stafford, P.M., Tzortzis, G. and Rastall, R.A. (2003) Synthesis of unsaturated aminopyranosides as possible transition state mimics for glycosidases. Journal of Carbohydrate Chemistry, 22 (7-8). pp. 705-717. ISSN 0732-8303 doi: 10.1081/car-120026469

Book or Report Section

Osborn, H.M.I. and Turkson, A. (2009) Sugars as pharmaceuticals. In: Gabius, H.-J. (ed.) The sugar code: fundamentals of glycosciences. Wiley-VCH, Weinheim, pp. 469-485. ISBN 9783527320899

Osborn, H.M.I., Evans, P.G. and Bezouska, K. (2008) Biomedicine of monosaccharides. In: Fraser-Reid, B.O., Tatsuta, K., Thiem, J., Coté, G.L., Flitsch, S., Ito, Y., Kondo, H., Nishimura, S.-i. and Yu, B. (eds.) Glycoscience: chemistry and chemical biology. Springer , Berlin, pp. 2399-2444. ISBN 9783540304296

Book

Osborn, H.M.I. (2003) Carbohydrates. Best synthetic methods. Academic Press, Oxford. ISBN 9780123120854

This list was generated on Wed Oct 29 23:02:38 2014 GMT.

Page navigation