Article

Chapman, C.M.C., Gibson, G.R., Todd, S. and Rowland, I. (2013) Comparative in vitro inhibition of urinary tract pathogens by single- and multi-strain probiotics. European Journal of Nutrition. ISSN 1436-6215 doi: 10.1007/s00394-013-0501-2

Kimani, P. K., Todd, S. and Stallard, N. (2013) Conditionally unbiased estimation in phase II/III clinical trials with early stopping for futility. Statistics in Medicine. ISSN 0277-6715 doi: 10.1002/sim.5757

Todd, S., Baksh, M. F. and Whitehead, J. (2012) Sequential methods for pharmacogenetic studies. Computational Statistics & Data Analysis, 56 (5). pp. 1221-1231. ISSN 0167-9473 doi: 10.1016/j.csda.2011.02.019

Todd, S., Valdes-Marquez, E. and West, J. (2012) A practical comparison of blinded methods for sample size reviews in survival data clinical trials. Pharmaceutical Statistics, 11 (2). pp. 141-148. ISSN 1539-1612 doi: 10.1002/pst.516

Vafeiadou, K., Weech, M., Sharma, V., Yaqoob, P., Todd, S., Williams, C., Jackson, K. and Lovegrove, J. (2012) A review of the evidence for the effects of total dietary fat, SFA, MUFA and n-6 PUFA on vascular function, endothelial progenitor cells and microparticles. British Journal of Nutrition, 107 (3). pp. 303-324. ISSN 1475-2662 doi: 10.1017/S0007114511004764

Parsons, N., Friede, T., Todd, S., Marquez, E. V., Chataway, J., Nicholas, R. and Stallard, N. (2012) An R package for implementing simulations for seamless phase II/III clinical trials using early outcomes for treatment selection. Computational Statistics & Data Analysis, 56 (5). pp. 1150-1160. ISSN 0167-9473 doi: 10.1016/j.csda.2010.10.027

Stallard, N. and Todd, S. (2011) Seamless phase II/III designs. Statistical Methods in Medical Research, 20 (6). pp. 623-634. ISSN 0962-2802 doi: 10.1177/0962280210379035

Friede, T., Parsons, N., Stallard, N., Todd, S., Valdes Marquez, E., Chataway, J. and Nicholas, R. (2011) Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: an application in multiple sclerosis. Statistics in Medicine, 30 (13). pp. 1528-1540. ISSN 1097-0258 doi: 10.1002/sim.4202

O'Kelly, M., Julious, S. A., Pyke, S., Day, S., Todd, S., Seldrup, J. and Matcham, J. (2011) Making available information from studies sponsored by the pharmaceutical industry: some current practices. Pharmaceutical Statistics, 10 (1). pp. 60-69. ISSN 1539-1612 doi: 10.1002/pst.430

Matcham, J., Julious, S., Pyke, S., O'Kelly, M., Todd, S., Seldrup, J. and Day, S. (2011) Proposed best practice for statisticians in the reporting and publication of pharmaceutical industry-sponsored clinical trials. Pharmaceutical Statistics, 10 (1). pp. 70-73. ISSN 1539-1612 doi: 10.1002/pst.417

Pyke, S., Julious, S. A., Day, S., O'Kelly, M., Todd, S., Matcham, J. and Seldrup, J. (2011) The potential for bias in reporting of industry-sponsored clinical trials. Pharmaceutical Statistics, 10 (1). pp. 74-79. ISSN 1539-1612 doi: 10.1002/pst.429

Chataway, J., Nicholas, R., Todd, S., Miller, D. H., Parsons, N., Valdes-Marquez, E., Stallard, N. and Friede, T. (2011) A novel adaptive design strategy increases the efficiency of clinical trials in secondary progressive multiple sclerosis. Multiple Sclerosis Journal, 17 (1). pp. 81-88. ISSN 1477-0970 doi: 10.1177/1352458510382129

Whitehead, J., Branson, M. and Todd, S. (2010) A combined score test for binary and ordinal endpoints from clinical trials. Statistics in Medicine, 29 (5). pp. 521-532. ISSN 0277-6715 doi: 10.1002/sim.3822

Friede, T., Nicholas, R., Stallard, N., Todd, S. C., Parsons, N., Valdes-Marquez, E. and Chataway, J. (2010) Refinement of the Clinical Scenario Evaluation Framework for Assessment of Competing Development Strategies with an Application to Multiple Sclerosis. Drug Information Journal, 44 (6). pp. 713-718. ISSN 0092-8615

Siqueira, A.L., Whitehead, A. and Todd, S. (2008) Active-control trials with binary data: a comparison of methods for testing superiority or non-inferiority using the odds ratio. Statistics in Medicine, 27 (3). pp. 353-370. ISSN 0277-6715 doi: 10.1002/sim.2975

Stallard, N., Todd, S. and Whitehead, J. (2008) Estimation following selection of the largest of two normal means. Journal of Statistical Planning and Inference, 138 (6). pp. 1629-1638. ISSN 0378-3758 doi: 10.1016/j.jspi.2007.05.045

Whitehead, A. , Whitehead, J. , Todd, S., Zhou, Y. and Smith, M. (2008) Fitting models for the joint action of two drugs using SAS(R). Pharmaceutical Statistics, 7 (4). pp. 272-284. ISSN 1539-1612 doi: 10.1002/pst.312

Todd, S. (2007) A 25-year review of sequential methodology in clinical studies. Stat Med, 26 (2). pp. 237-52. ISSN 0277-6715 doi: 10.1002/sim.2763

Baksh, M.F., Haars, G., Todd, S., Van Noord, P.A.H. and Whitehead, J. (2006) Comparing correlations of continuous observations from two independent populations using a sequential approach. Statistics in Medicine, 25 (24). pp. 4293-4310. ISSN 0277-6715 doi: 10.1002/sim.2676

Baksh, M. F., Todd, S., Whitehead, J. and Lucini, M. M. (2005) Design considerations in the sequential analysis of matched case–control data. Statistics in Medicine, 24 (6). pp. 853-867. ISSN 0277-6715 doi: 10.1002/sim.1968

Perkins, G.D., Barrett, H., Bullock, I. , Gabbott, D.A., Todd, S. and Bion, J.F. (2005) The Acute Care Undergraduate TEaching (ACUTE) initiative: consensus development of core competencies in acute care for undergraduates in the United Kingdom. Intensive Care Medicine, 31 (12). pp. 1627-1633. ISSN 0342-4642 doi: 10.1007/s00134-005-2837-4

Siqueira, A., Whitehead, A., Todd, S. and Lucini, M. (2005) Comparison of sample size formulae for 2x2 cross-over designs applied to bioequivalence studies. Pharmaceutical Statistics, 4 (4). pp. 233-243. ISSN 1539-1612 doi: 10.1002/pst.183

Stallard, N. and Todd, S. (2005) Point estimates and confidence regions for sequential trials involving selection. Journal of Statistical Planning and Inference, 135 (1). pp. 402-419. ISSN 0378-3758 doi: 10.1016/j.jspi.2004.05.006

Rogers, M. S., Chang, A. M. Z. and Todd, S. (2005) Using group-sequential analysis to achieve the optimal sample size. Bjog-an International Journal of Obstetrics and Gynaecology, 112 (5). pp. 529-533. ISSN 1470-0328 doi: 10.1111/j.1471-0528.2005.00479.x

Kelly, P.J., Stallard, N. and Todd, S. (2005) An adaptive group sequential design for phase II/III clinical trials that select a single treatment from several. Journal of Biopharmaceutical Statistics, 15 (4). pp. 641-658. ISSN 1054-3406 doi: 10.1081/BIP-200062857

Todd, S. and Stallard, N. (2005) A new clinical trial design combining phases II and III: sequential designs with treatment selection and a change of endpoint. Drug Information Journal, 39. pp. 109-118. ISSN 0092-8615

Kelly, P.J., Sooriyarachchi, M.R., Stallard, N. and Todd, S. (2005) A practical comparison of group-sequential and adaptive designs. Journal of Biopharmaceutical Statistics, 15 (4). pp. 719-738. ISSN 1054-3406 doi: 10.1081/BIP-200062859

Whitehead, J. and Todd, S. (2004) The double triangular test in practice. Pharmaceutical Statistics, 3 (1). pp. 39-49. ISSN 1539-1612 doi: 10.1002/pst.91

Elliot, J.M., Virankabutra, T., Jones, S., Tanudsintum, S., Lipkin, G., Todd, S. and Bion, J. (2003) Erythropoietin mimics the acute phase response in critical illness. Clinical Care, 7. R35-R40. ISSN 1364-8535 doi: 10.1186/cc2185

Stallard, N. and Todd, S. (2003) Sequential designs for phase III clinical trials incorporating treatment selection. Statistics in Medicine, 22 (5). pp. 689-703. ISSN 0277-6715 doi: 10.1002/sim.1362

Todd, S. (2003) An adaptive approach to implementing bivariate group sequential clinical trial designs. Journal of Biopharmaceutical Statistics, 13 (4). pp. 605-619. ISSN 1054-3406 doi: 10.1081/BIP-120024197

Report

Branson, M., Todd, S. and Whitehead, J. (2004) Estimating the covariances between efficient score test statistics in comparative studies. Applied Statistics Technical Report. 04/2. The University of Reading

Siqueira, A.L., Whitehead, A., Todd, S. and Lucini, M.M. (2004) On sample size calculations for 2x2 cross-over designs applied to bioequivalence studies. Applied Statistics Technical Report. 04/4. The University of Reading

Kelly, P., Stallard, N. and Todd, S. (2003) An adaptive group sequential design for clinical trials that involve treatment selection. Applied Statistics Technical Report. 03/1. The University of Reading