Article

De La Cruz Molina, A. V., Durmaz, G. ORCID: https://orcid.org/0000-0003-3423-8108, Oruna-Concha, M. J. ORCID: https://orcid.org/0000-0001-7916-1592, Charalampopoulos, D. ORCID: https://orcid.org/0000-0003-1269-8402 and Jauregi, P. ORCID: https://orcid.org/0000-0003-4438-191X (2025) Whey protein based colloidal gas aphrons combined with solid–liquid extraction as an integrated green separation of phenolics from fruit based by-products. Separation and Purification Technology, 361 (3). 131526. ISSN 1383-5866 doi: 10.1016/j.seppur.2025.131526

De La Cruz Molina, A. V., Gonçalves, C., Neto, M. D., Pastrana, L. ORCID: https://orcid.org/0000-0002-0852-826X, Jauregi, P. ORCID: https://orcid.org/0000-0003-4438-191X and Amado, I. R. (2023) Whey–pectin microcapsules improve the stability of grape marc phenolics during digestion. Journal of Food Science, 88 (12). pp. 4892-4906. ISSN 1750-3841 doi: 10.1111/1750-3841.16806

de Albuquerque, P. B. S. ORCID: https://orcid.org/0000-0002-6310-1365, de Souza, M. P. ORCID: https://orcid.org/0000-0002-8629-143X, Bourbon, A. I. ORCID: https://orcid.org/0000-0002-5845-7359, Cerqueira, M. A. ORCID: https://orcid.org/0000-0001-6614-3942, Pastrana, L. ORCID: https://orcid.org/0000-0002-6637-3462, Jauregi, P. ORCID: https://orcid.org/0000-0003-4438-191X, Teixeira, J. A. ORCID: https://orcid.org/0000-0002-4918-3704 and das Graças Carneiro-da-Cunha, M. (2023) Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based films. Applied Nano, 4 (2). pp. 159-177. ISSN 2673-3501 doi: 10.3390/applnano4020009

Chamata, Y., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 and Jauregi, P. (2021) Whey-derived peptides at the heart of the COVID-19 pandemic. International Journal of Molecular Sciences, 22 (21). 11662. ISSN 1422-0067 doi: 10.3390/ijms222111662

Jauregi, P., Guo, Y. and Adeloye, J. B. (2021) Whey proteins-polyphenols interactions can be exploited to reduce astringency or increase solubility and stability of bioactives in foods. Food Research International, 141. 110019. ISSN 0963-9969 doi: 10.1016/j.foodres.2020.110019

Kourmentza, K., Gromada, X., Michael, N., Degraeve, C., Vanier, G., Ravallec, R., Coutte, F., Karatzas, K.-A. and Jauregi, P. (2021) Antimicrobial activity of lipopeptide biosurfactants against foodborne pathogen and food spoilage microorganisms and their cytotoxicity. Frontiers in Microbiology, 11. 561060. ISSN 1664-302X doi: 10.3389/fmicb.2020.561060

Olatujoye, J. B., Methven, L. and Jauregi, P. (2020) Effect of β-lactoglobulin on perception of astringency in red wine as measured by sequential profiling. LWT, 130. 109611. ISSN 0023-6438 doi: 10.1016/j.lwt.2020.109611

Wang, Y., Zhao, J., Zhang, W., Liu, C., Jauregi, P. and Huang, M. (2020) Modification of heat-induced whey protein gels by basic amino acids. Food Hydrocolloids, 100. 105397. ISSN 0268-005X doi: 10.1016/j.foodhyd.2019.105397

Chamata, Y., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 and Jauregi, P. (2020) Whey-derived peptides interactions with ACE by molecular docking as a potential predictive tool of natural ACE inhibitors. International Journal of Molecular Sciences, 21 (3). e864. ISSN 1422-0067 doi: 10.3390/ijms21030864

de Carvalho, N. M., Walton, G. E. ORCID: https://orcid.org/0000-0001-5426-5635, Poveda, C. G., Silva, S.N., Amorim, M., Madureira, A. R., Pintado, M. E., Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476 and Jauregi, P. (2019) Study of in vitro digestion of Tenebrio molitor flour for evaluation of its impact on the human gut microbiota. Journal of Functional Foods, 59. pp. 101-109. ISSN 1756-4646 doi: 10.1016/j.jff.2019.05.024

Cristea, E., Sturza, R., Jauregi, P., Niculaua, M., Ghendov-Moșanu, A. and Patras, A. (2019) Influence of pH and ionic strength on the color parameters and antioxidant properties of an ethanolic red grape marc extract. Journal of Food Biochemistry, 43 (4). e12788. ISSN 1745-4514 doi: 10.1111/jfbc.12788

MohdMaidin, N., Oruna-Concha, M. J. ORCID: https://orcid.org/0000-0001-7916-1592 and Jauregi, P. (2019) Surfactant TWEEN20 provides stabilisation effect on anthocyanins extracted from red grape pomace. Food Chemistry, 271. pp. 224-231. ISSN 0308-8146 doi: 10.1016/j.foodchem.2018.07.083

Gonzalez-Gonzalez, C. R., Machado, J., Correia, S., McCartney, A. L., Elmore, J. S. ORCID: https://orcid.org/0000-0002-2685-1773 and Jauregi, P. (2019) Highly proteolytic bacteria from semi-ripened Chiapas cheese elicit angiotensin-I converting enzyme inhibition and antioxidant activity. LWT-Food Science and Technology, 111. pp. 449-456. ISSN 0023-6438 doi: 10.1016/j.lwt.2019.05.039

Guo, Y., Michael, N., Fonseca Madrigal, J., Sosa Aguirre, C. and Jauregi, P. (2019) Protein hydrolysate from Pterygoplichthys disjunctivus, armoured catfish, with high antioxidant activity. Molecules, 24 (8). 1628. ISSN 1420-3049 doi: 10.3390/molecules24081628

Guo, Y. and Jauregi, P. (2018) Protective effect of β-Lactoglobulin against heat induced loss of antioxidant activity of resveratrol. Food Chemistry, 266. pp. 101-109. ISSN 0308-8146 doi: 10.1016/j.foodchem.2018.05.108

Noriega, D., Zuñiga, M. E., Soto, C., MohdMaidin, N., Michael, N. and Jauregi, P. (2018) Colloidal gas aphrons separation to obtain polyphenol rich fractions from artichoke agro-industrial discards. Food and Bioproducts Processing, 110. pp. 50-59. ISSN 0960-3085 doi: 10.1016/j.fbp.2018.04.007

Mohd Maidin, N., Michael, N., Oruna-Concha, M. J. ORCID: https://orcid.org/0000-0001-7916-1592 and Jauregi, P. (2018) Polyphenols extracted from red grape pomace by a surfactant based method show enhanced collagenase and elastase inhibitory activity. Journal of Chemical Technology and Biotechnology, 93 (7). pp. 1916-1924. ISSN 0268-2575 doi: 10.1002/jctb.5459

Moreno-Montoro, M., Jauregi, P., Navarro-Alarcón, M., Olalla-Herrera, M., Giménez-Martínez, R., Amigo, L. and Miralles, B. (2018) Bioaccessible peptides released by in vitro gastrointestinal digestion of fermented goat milks. Analytical and Bioanalytical Chemistry, 410 (15). pp. 3597-3606. ISSN 1618-2650 doi: 10.1007/s00216-018-0983-0

Guo, Y., Harris, P., Kaur, A., Pastrana, L. and Jauregi, P. (2017) Characterisation of β-lactoglobulin nanoparticles and their binding to caffeine. Food Hydrocolloids, 71. pp. 85-93. ISSN 0268-005X doi: 10.1016/j.foodhyd.2017.04.027

Moreno-Montoro, M., Olalla-Herrera, M., Rufián-Henares, J. Á., Martínez, R. G., Miralles, B., Bergillos, T., Navarro-Alarcón, M. and Jauregi, P. (2017) Antioxidant, ACE-inhibitory and antimicrobial activity of fermented goat milk: activity and physicochemical property relationship of the peptide components. Food & Function, 8 (8). pp. 2783-2791. ISSN 2042-650X doi: 10.1039/c7fo00666g

De Andrade, C. J., De Andrade, L. M., Rocco, S. A., Sforça, M. L., Pastore, G. M. and Jauregi, P. (2017) A novel approach for the production and purification of mannosylerythritol lipids (MEL) by Pseudozyma tsukubaensis using cassava wastewater as substrate. Separation and Purification Technology, 180. pp. 157-167. ISSN 1383-5866 doi: 10.1016/j.seppur.2017.02.045

De Andrade, C. J., Barros, F. F. C., De Andrade, L. M., Roco, S. A., Sforca, M. L., Pastore, G. M. and Jauregi, P. (2016) Ultrafiltration based purification strategies for surfactin produced by bacillus subtilis lb5a using cassava wastewater as substrate. Journal of Chemical Technology and Biotechnology, 91 (12). pp. 3018-3027. ISSN 1097-4660 doi: 10.1002/jctb.4928

Jauregi, P., Olatujoye, J. B., Cabezudo, I., Frazier, R. A. ORCID: https://orcid.org/0000-0003-4313-0019 and Gordon, M. H. (2016) Astringency reduction in red wine by whey proteins. Food Chemistry, 199. pp. 547-555. ISSN 0308-8146 doi: 10.1016/j.foodchem.2015.12.052

Santos-Ebinuma, V. C., Teixeira, M. F. S., Pessoa, A. and Jauregi, P. (2016) Separation of natural colorants from the fermented broth of filamentous fungi using colloidal gas aphrons. Separation and Purification Technology, 163. pp. 100-108. ISSN 1383-5866 doi: 10.1016/j.seppur.2016.02.037

Spigno, G., Amendola, D., Dahmoune, F. and Jauregi, P. (2015) Colloidal gas aphrons based separation process for the purification and fractionation of natural phenolic extracts. Food and Bioproducts Processing, 94. pp. 434-442. ISSN 0960-3085 doi: 10.1016/j.fbp.2014.06.002

Pa’ee, K. F., Gibson, T., Marakilova, B. and Jauregi, P. (2015) Production of acid whey hydrolysates applying an integrative process: effect of calcium on process performance. Process Biochemistry, 50 (2). pp. 302-310. ISSN 1359-5113 doi: 10.1016/j.procbio.2014.11.011

Hamley, I. W. ORCID: https://orcid.org/0000-0002-4549-0926, Dehsorkhi, A., Jauregi, P., Seitsonen, J., Ruokolainen, J., Coutte, F., Chataigne, G. and Jacques, P. (2013) Self-assembly of three bacterially-derived bioactive lipopeptides. Soft Matter, 9 (40). pp. 9572-9578. ISSN 1744-683X doi: 10.1039/c3sm51514a

Jauregi, P., Coutte, F., Catiau, L., Lecouturier, D. and Jacques, P. (2013) Micelle size characterization of lipopeptides produced by B. subtilis and their recovery by the two-step ultrafiltration process. Separation and Purification Technology, 104. pp. 175-182. ISSN 1383-5866 doi: 10.1016/j.seppur.2012.11.017

Welderufael, F. T., Gibson, T. and Jauregi, P. (2012) Production of angiotensin converting enzyme inhibitory peptides from β-lactoglobulin and casein derived peptides: an integrative approach. Biotechnology Progress, 28 (3). pp. 746-755. ISSN 8756-7938 doi: 10.1002/btpr.1541

Welderufael, F. T., Gibson, T., Methven, L. and Jauregi, P. (2012) Chemical characterisation and determination of sensory attributes of hydrolysates produced by enzymatic hydrolysis of whey proteins following a novel integrative process. Food Chemistry, 134 (4). pp. 1947-1958. ISSN 0308-8146 doi: 10.1016/j.foodchem.2012.03.113

Gonzalez-Gonzalez, C. R., Tuohy, K. M. and Jauregi, P. (2011) Production of angiotensin-I-converting enzyme (ACE) inhibitory activity in milk fermented with probiotic strains: Effects of calcium, pH and peptides on the ACE-inhibitory activity. International Dairy Journal, 21 (9). pp. 615-622. ISSN 0958-6946 doi: 10.1016/j.idairyj.2011.04.001

Isa, M. H. M., Frazier, R. ORCID: https://orcid.org/0000-0003-4313-0019 and Jauregi, P. (2011) Surface activity of surfactin recovered and purified from fermentation broth using a two-step ultrafiltration (UF) process. Sains Malaysiana, 40 (9). pp. 1043-1048. ISSN 0126-6039

Dermiki, M., Bourquin, A.-L. and Jauregi, P. (2010) Separation of astaxanthin from cells of Phaffia rhodozyma using colloidal gas aphrons (CGA) in a flotation column. Biotechnology Progress, 26 (2). pp. 477-487. ISSN 8756-7938 doi: 10.1002/btpr.340

Spigno, G., Dermiki, M., Pastori, C., Casanova, F. and Jauregi, P. (2010) Recovery of gallic acid with colloidal gas aphrons generated from a cationic surfactant. Separation and Purification Technology, 71 (1). pp. 56-62. ISSN 1383-5866 doi: 10.1016/j.seppur.2009.11.002

Ortiz-Chao, P., Gomez-Ruiz, J.A., Rastall, R.A., Mills, D., Cramer, R. ORCID: https://orcid.org/0000-0002-8037-2511, Pihlanto, A., Korhonen, H. and Jauregi, P. (2009) Production of novel ACE inhibitory peptides from beta-lactoglobulin using Protease N Amano. International Dairy Journal, 19 (2). pp. 69-76. ISSN 0958-6946 doi: 10.1016/j.idairyj.2008.07.011

Ortiz-Chao, P., Gómez-Ruiz, J. A., Rastall, R. A., Mills, D., Cramer, R., Pihlanto, A., Korhonen, H. and Jauregi, P. (2009) Production of novel ACE inhibitory peptides from β-lactoglobulin using Protease N Amano. International Dairy Journal, 19 (2). pp. 69-76. ISSN 0958-6946 doi: 10.1016/j.idairyj.2008.07.011

Dermiki, M., Gordon, M.H. and Jauregi, P. (2009) Recovery of astaxanthin using colloidal gas aphrons (CGA): a mechanistic study. Separation and Purification Technology, 65 (S1). pp. 54-64. ISSN 1383-5866 doi: 10.1016/j.seppur.2007.12.023

Isa, M.H.M., Frazier, R. A. ORCID: https://orcid.org/0000-0003-4313-0019 and Jauregi, P. (2008) A further study of the recovery and purification of surfactin from fermentation broth by membrane filtration. Separation and Purification Technology, 64 (2). pp. 176-182. ISSN 1383-5866 doi: 10.1016/j.seppur.2008.09.008

Jauregi, P. (2008) Bioactive peptides from food proteins: new opportunities and challenges. Food Science and Technology Bulletin: Functional Foods, 5 (2). pp. 11-25. ISSN 1476-2137 doi: 10.1616/1476-2137.15305

Goodall, S., Grandison, A. S., Jauregi, P. J. and Price, J. (2008) Selective separation of the major whey proteins using ion exchange membranes. Journal of Dairy Science, 91 (1). pp. 1-10. ISSN 0022-0302 doi: 10.3168/jds.2007-0539

Dermiki, M., Gordon, M.H. and Jauregi, P. (2008) The use of colloidal gas aphrons as novel downstream processing for the recovery of astaxanthin from cells of Phaffia rhodozyma. Journal of Chemical Technology and Biotechnology, 83 (2). pp. 174-182. ISSN 0268-2575 doi: 10.1002/jctb.1855

Castelletto, V., Krysmann, M., Kelarakis, A. and Jauregi, P. (2007) Complex formation of bovine serum albumin with a poly(ethylene glycol) lipid conjugate. Biomacromolecules, 8 (7). pp. 2244-2249. ISSN 1525-7797 doi: 10.1021/bm070116o

Isa, M.H.M., Coraglia, D.E., Frazier, R. ORCID: https://orcid.org/0000-0003-4313-0019 and Jauregi, P. (2007) Recovery and purification of surfactin from fermentation broth by a two-step ultrafiltration process. Journal of Membrane Science, 296 (1-2). pp. 51-57. ISSN 0376-7388 doi: 10.1016/j.memsci.2007.03.023

Alves, R.W., de Souza, A.A.U., de Souza, S.M.d.A.G.U. and Jauregi, P. (2006) Recovery of norbixin from a raw extraction solution of annatto pigments using colloidal gas aphrons (CGAs). Separation and Purification Technology, 48 (2). pp. 208-213. ISSN 1383-5866 doi: 10.1016/j.seppur.2005.07.014

Spigno, G. and Jauregi, P. (2005) Recovery of gallic acid with colloidal gas aphrons (CGA). International Journal of Food Engineering, 1 (4). p. 5. ISSN 1556-3758 doi: 10.2202/1556-3758.1038

Fuda, E., Bhatia, D., Pyle, D.L. and Jauregi, P. (2005) Selective separation of beta-lactoglobulin from sweet whey using CGAs generated from the cationic surfactant CTAB. Biotechnology and Bioengineering, 90 (5). pp. 532-542. ISSN 0006-3592 doi: 10.1002/bit.20412

Fuda, E. and Jauregi, P. (2005) An insight into the mechanism of protein separation by colloidal gas aphrons (CGA) generated from ionic surfactants. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 843 (2). pp. 317-326. ISSN 1570-0232 doi: 10.1016/j.jchromb.2006.06.032

Fuda, E., Jauregi, P. and Pyle, D.L. (2004) Recovery of lactoferrin and lactoperoxidase from sweet whey using colloidal gas aphrons (CGAs) generated from an anionic surfactant, AOT. Biotechnology Progress, 20 (2). pp. 514-525. ISSN 8756-7938 doi: 10.1021/bp034198d

Book or Report Section

Pastrana, L. and Jauregi, P. (2017) Basic biochemistry. In: Pandey , A. and Teixeira , J. (eds.) Current Developments in Biotechnology and Bioengineering: Foundations of Biotechnology and Bioengineering. Elsevier, Amsterdam , pp. 33-58. ISBN 9780444636683 doi: 10.1016/B978-0-444-63668-3.00002-0