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Jump to: An investigation of parent-child interactions in anxious adolescents and a pilot evaluation of a novel family treatment | Defining the role of Death Associated Protein Kinase 1 in cell fate using genomic and proteomic analysis | Dissecting the molecular basis of LRRK2 Parkinson's Disease | Dissecting the role of LRRK2 in the regulation of autophagy | Enhancement of Learning and Memory by Flavonoids | Further analysis and development on CRN portfolio UKCRN 'Ocular accommodation and vergence over the lifespan | High resolution systems biology to determine the role of gut microbiota on type 2 diabetes | Improving interventions for anxious youth: developing understanding and treatment of parents' cognition's and behaviours | MICA: Reducing cardiovascular disease risk through sustainable replacement of saturated fatty acids in milk and dairy products | Molecular bases of tick-borne flavivirus transmission | Neural underpinnings of emotional responding and regulation: antecedents and correlates | Prenatal and Infancy Origins of Biological and Social-Cognitive Processes in Disruptive Problems in Children Aged 7-9 Years | Protein sumoylation in platelets: a potential new signalling paradigm in the control of haemostasis and thrombosis | Reducing saturated fatty acids in the food chain thorugh alteration of milk fat composition DRINC. | Reducing saturated fatty acids in the food chain through alteration of milk fat composition | Reward and empathy in autism - MRC EXTENSION | Studentship DTG Competition 2011 | Study of the role of gap junctions and connexin hemichannels in the control of platlet function, haemostasis and thrombosis | Study of the role of secreted platelet thiol isomerases in the regulation of platelet function, haemostasis and thrombosis | The Treatment of Child Anxiety Disorders via Guided CBT Self-Help: A Randomised Controlled Trial - MRC EXTENSION | The identification of the disulphide bonds in HIV gp120 whose reduction is required for cell entry and their manipulation for immunogen design | The modulation of catecholamine-thiol adduct-induced neuronal injury by flavonoids and their metabolites | The physiological importance and integration of receptor-mediated inhibitory mechanisms in platelets | The physiological importance and integration of receptor-mediated inhibitory mechanisms in platelets in health and disease | Therapeutic corneal stem cell delivery using a bioadhesive in situ gelling system | Treatment of Child Anxiety Disorder in the Context of Maternal Anxiety: A Randomised Controlled Trial | Typical and atypical ocular accommodation and convergence characteristics and relationships over the life span | Using FMRI and TMS to probe the functional connectivity of prefrontal cortex and amygdala in top-down regulation of emotion | Using Surrogate Endpoints for Decision-Making in Adaptive Seamless Designs
Number of items: 103.

An investigation of parent-child interactions in anxious adolescents and a pilot evaluation of a novel family treatment

Smart, K., Smith, L., Harvey, K. ORCID: https://orcid.org/0000-0002-6819-0934 and Waite, P. ORCID: https://orcid.org/0000-0002-1967-8028 (2023) The acceptability of a therapist-assisted internet-delivered cognitive behaviour therapy program for the treatment of anxiety disorders in adolescents: a qualitative study. European Child & Adolescent Psychiatry, 32. pp. 661-673. ISSN 1435-165X doi: https://doi.org/10.1007/s00787-021-01903-6

Waite, P. ORCID: https://orcid.org/0000-0002-1967-8028, Marshall, T. and Creswell, C. (2019) A randomized controlled trial of internet-delivered cognitive behaviour therapy for adolescent anxiety disorders in a routine clinical care setting with and without parent sessions. Child and Adolescent Mental Health, 24 (3). pp. 242-250. ISSN 1475-3588 doi: https://doi.org/10.1111/camh.12311

Waite, P. ORCID: https://orcid.org/0000-0002-1967-8028, Codd, J. and Creswell, C. (2015) Interpretation of ambiguity: differences between children and adolescents with and without an anxiety disorder. Journal of Affective Disorders, 188. pp. 194-201. ISSN 0165-0327 doi: https://doi.org/10.1016/j.jad.2015.08.022

Waite, P. ORCID: https://orcid.org/0000-0002-1967-8028 and Creswell, C. (2014) Children and adolescents referred for treatment of anxiety disorders: differences in clinical characteristics. Journal of Affective Disorders, 167. pp. 326-332. ISSN 0165-0327 doi: https://doi.org/10.1016/j.jad.2014.06.028

Waite, P. ORCID: https://orcid.org/0000-0002-1967-8028, Parkinson, M., Willetts, L. and Creswell, C. (2014) Modifying the family environment. In: Sburlati, E.S., Lyneham, H.J., Schniering, C.A. and Rapee, R.M. (eds.) Evidence-based CBT for anxiety and depression in children and adolescents: a competencies based approach. John Wiley & Sons, Chichester, pp. 275-300. ISBN 9781118469255

Creswell, C., Waite, P. ORCID: https://orcid.org/0000-0002-1967-8028 and Cooper, P. J. (2014) Assessment and management of anxiety disorders in children and adolescents. Archives of Disease in Childhood, 99 (7). pp. 674-678. ISSN 0003-9888 doi: https://doi.org/10.1136/archdischild-2013-303768

Waite, P. ORCID: https://orcid.org/0000-0002-1967-8028, Whittington, L. and Creswell, C. (2014) Parent-child interactions and adolescent anxiety: a systematic review. Psychopathology Review, 1 (1). pp. 51-76. ISSN 2051-8315 doi: https://doi.org/10.5127/pr.033213

Defining the role of Death Associated Protein Kinase 1 in cell fate using genomic and proteomic analysis

Tomkins, J. E., Dihanich, S., Beilina, A., Ferrari, R., Ilacqua, N., Cookson, M. R., Lewis, P. A. and Manzoni, C. (2018) Comparative protein interaction network analysis identifies shared and distinct functions for the human ROCO proteins. Proteomics, 18 (10). 1700444. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.201700444

Dissecting the molecular basis of LRRK2 Parkinson's Disease

Kara, E., Tucci, A., Manzoni, C., Lynch, D. S., Elpidorou, M., Bettencourt, C., Chelban, V., Manole, A., Hamed, S., Haridy, N., Federoff, M., Preza, E., Hughes, D., Pittman, A., Jaunmuktane, Z., Brandner, S., Xiromerisiou, G., Wiethoff, S., Schottlaender, L., Proukakis, C., Morris, H., Warner, T., Bhatia, K., Korlipara, P., Singleton, A., Hardy, J., Wood, N., Lewis, P. and Houlden, H. (2016) Genetic and phenotypic characterization of complex hereditary spastic paraplegia. Brain : A Journal of Neurology, 139 (7). pp. 1904-1918. ISSN 1460-2156 doi: https://doi.org/10.1093/brain/aww111

Kiely, A., Ling, H., Asi, Y., Kara, E., Proukakis, C., Schapira, A., Morris, H., Roberts, H., Lubbe, S., Limousin, P., Lewis, P., Lees, A., Quinn, N., Hardy, J., Love, S., Revesz, T., Houlden, H. and Holton, J. (2015) Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation. Molecular Neurodegeneration, 10 (1). 41. ISSN 1750-1326 doi: https://doi.org/10.1186/s13024-015-0038-3

Manzoni, C., Denny, P., Lovering, R. C. and Lewis, P. A. (2015) Computational analysis of the LRRK2 interactome. PeerJ, 3. 778. ISSN 2167-8359 doi: https://doi.org/10.7717/peerj.778

Tomkins, J. E., Dihanich, S., Beilina, A., Ferrari, R., Ilacqua, N., Cookson, M. R., Lewis, P. A. and Manzoni, C. (2018) Comparative protein interaction network analysis identifies shared and distinct functions for the human ROCO proteins. Proteomics, 18 (10). 1700444. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.201700444

Manzoni, C., Mamais, A., Dihanich, S., Soutar, M. P. M., Plun-Favreau, H., Bandopadhyay, R., Abeti, R., Giunti, P., Hardy, J., Cookson, M. R., Tooze, S. A. and Lewis, P. A. (2018) mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition. Bioscience Reports, 38 (2). BSR20171669. ISSN 0144-8463 doi: https://doi.org/10.1042/BSR20171669

Ferrari, R., Lovering, R. C., Hardy, J., Lewis, P. A. and Manzoni, C. (2017) Weighted protein interaction network analysis of frontotemporal dementia. Journal of Proteome Research, 16 (2). pp. 999-1013. ISSN 1535-3907 doi: https://doi.org/10.1021/acs.jproteome.6b00934

Manzoni, C., Mamais, A., Roosen, D. A., Dihanich, S., Soutar, M. P. M., Plun-Favreau, H., Bandopadhyay, R., Hardy, J., Tooze, S. A., Cookson, M. R. and Lewis, P. A. (2016) mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1. Scientific Reports, 6. 35106. ISSN 2045-2322 doi: https://doi.org/10.1038/srep35106

Dissecting the role of LRRK2 in the regulation of autophagy

Kara, E., Tucci, A., Manzoni, C., Lynch, D. S., Elpidorou, M., Bettencourt, C., Chelban, V., Manole, A., Hamed, S., Haridy, N., Federoff, M., Preza, E., Hughes, D., Pittman, A., Jaunmuktane, Z., Brandner, S., Xiromerisiou, G., Wiethoff, S., Schottlaender, L., Proukakis, C., Morris, H., Warner, T., Bhatia, K., Korlipara, P., Singleton, A., Hardy, J., Wood, N., Lewis, P. and Houlden, H. (2016) Genetic and phenotypic characterization of complex hereditary spastic paraplegia. Brain : A Journal of Neurology, 139 (7). pp. 1904-1918. ISSN 1460-2156 doi: https://doi.org/10.1093/brain/aww111

Kiely, A., Ling, H., Asi, Y., Kara, E., Proukakis, C., Schapira, A., Morris, H., Roberts, H., Lubbe, S., Limousin, P., Lewis, P., Lees, A., Quinn, N., Hardy, J., Love, S., Revesz, T., Houlden, H. and Holton, J. (2015) Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation. Molecular Neurodegeneration, 10 (1). 41. ISSN 1750-1326 doi: https://doi.org/10.1186/s13024-015-0038-3

Manzoni, C., Denny, P., Lovering, R. C. and Lewis, P. A. (2015) Computational analysis of the LRRK2 interactome. PeerJ, 3. 778. ISSN 2167-8359 doi: https://doi.org/10.7717/peerj.778

Ebanks, K., Lewis, P. A. and Bandopadhyay, R. (2020) Vesicular dysfunction and the pathogenesis of Parkinson's disease: clues from genetic studies. Frontiers in Neuroscience, 13. 1381. ISSN 1662-453X doi: https://doi.org/10.3389/fnins.2019.01381

Leksmono, C., Manzoni, C., Tomkins, J., Lucchesi, W., Cottrell, G. ORCID: https://orcid.org/0000-0001-9098-7627 and Lewis, P. A. (2018) Measuring lactase enzymatic activity in the teaching lab. Journal of Visualized Experiments (138). e54377. ISSN 1940-087X doi: https://doi.org/10.3791/54377

Civiero, L., Dihanich, S., Lewis, P. A. and Greggio, E. (2014) Genetic, structural, and molecular insights into the function of ras of complex proteins domains. Chemistry and Biology, 21 (7). pp. 809-818. ISSN 1074-5521 doi: https://doi.org/10.1016/j.chembiol.2014.05.010

Tomkins, J. E., Dihanich, S., Beilina, A., Ferrari, R., Ilacqua, N., Cookson, M. R., Lewis, P. A. and Manzoni, C. (2018) Comparative protein interaction network analysis identifies shared and distinct functions for the human ROCO proteins. Proteomics, 18 (10). 1700444. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.201700444

Manzoni, C., Mamais, A., Dihanich, S., Soutar, M. P. M., Plun-Favreau, H., Bandopadhyay, R., Abeti, R., Giunti, P., Hardy, J., Cookson, M. R., Tooze, S. A. and Lewis, P. A. (2018) mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition. Bioscience Reports, 38 (2). BSR20171669. ISSN 0144-8463 doi: https://doi.org/10.1042/BSR20171669

Ferrari, R., Lovering, R. C., Hardy, J., Lewis, P. A. and Manzoni, C. (2017) Weighted protein interaction network analysis of frontotemporal dementia. Journal of Proteome Research, 16 (2). pp. 999-1013. ISSN 1535-3907 doi: https://doi.org/10.1021/acs.jproteome.6b00934

Manzoni, C., Mamais, A., Roosen, D. A., Dihanich, S., Soutar, M. P. M., Plun-Favreau, H., Bandopadhyay, R., Hardy, J., Tooze, S. A., Cookson, M. R. and Lewis, P. A. (2016) mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1. Scientific Reports, 6. 35106. ISSN 2045-2322 doi: https://doi.org/10.1038/srep35106

Enhancement of Learning and Memory by Flavonoids

Vauzour, D., Pinto, J. T., Cooper, A. J. L. and Spencer, J. P. E. (2014) The neurotoxicity of 5-S-cysteinyldopamine is mediated by the early activation of ERK1/2 followed by the subsequent activation of ASK1/JNK1/2 pro-apoptotic signalling. Biochemical Journal, 463 (1). pp. 41-52. ISSN 0264-6021 doi: https://doi.org/10.1042/BJ20131519

Further analysis and development on CRN portfolio UKCRN 'Ocular accommodation and vergence over the lifespan

Horwood, A. ORCID: https://orcid.org/0000-0003-0886-9686 (2016) Convergence accommodation in orthoptic practice. British & Irish Orthoptic Journal, 13. pp. 2-8. ISSN 1743-9868 doi: https://doi.org/10.22599/bioj.95

High resolution systems biology to determine the role of gut microbiota on type 2 diabetes

Mora Ortiz, M. and Claus, S. P. (2017) Choline theft-an inside job. Cell Metabolism, 22 (3). pp. 253-255. ISSN 1550-4131 doi: https://doi.org/10.1016/j.chom.2017.08.017

Improving interventions for anxious youth: developing understanding and treatment of parents' cognition's and behaviours

Halldorsson, B., Draisey, J., Cooper, P. and Creswell, C. (2018) Symptoms of social anxiety, depression and stress in parents of children with social anxiety disorder. British Journal of Clinical Psychology, 57 (2). pp. 148-162. ISSN 0144-6657 doi: https://doi.org/10.1111/bjc.12170

Orchard, F., Apetroaia, A., Clarke, K. and Creswell, C. (2017) Cognitive bias modification of interpretation in children with social anxiety disorder. Journal of Anxiety Disorders, 45. pp. 1-8. ISSN 0887-6185 doi: https://doi.org/10.1016/j.janxdis.2016.10.012

Hiller, R. M., Apetroaia, A., Clarke, K., Hughes, Z., Orchard, F., Parkinson, M. and Creswell, C. (2016) The effect of targeting tolerance of children's negative emotions among anxious parents of children with anxiety disorders: a pilot randomised controlled trial. Journal of Anxiety Disorders, 42. pp. 52-59. ISSN 0887-6185 doi: https://doi.org/10.1016/j.janxdis.2016.05.009

Apetroaia, A., Hill, C. and Creswell, C. (2015) Parental responsibility beliefs: associations with parental anxiety and behaviours in the context of childhood anxiety disorders. Journal of Affective Disorders, 188. pp. 127-133. ISSN 0165-0327 doi: https://doi.org/10.1016/j.jad.2015.08.059

Halls, G., Cooper, P. J. and Creswell, C. (2015) Social communication deficits: specific associations with Social Anxiety Disorder. Journal of Affective Disorders, 172. pp. 38-42. ISSN 0165-0327 doi: https://doi.org/10.1016/j.jad.2014.09.040

Alkozei, A., Creswell, C., Cooper, P. and Allen, J. (2015) Autonomic arousal in childhood anxiety disorders: associations with state anxiety and social anxiety disorder. Journal of Affective Disorders, 175. pp. 25-33. ISSN 0165-0327 doi: https://doi.org/10.1016/j.jad.2014.11.056

MICA: Reducing cardiovascular disease risk through sustainable replacement of saturated fatty acids in milk and dairy products

Markey, O., Vasilopoulou, D., Kliem, K. E. ORCID: https://orcid.org/0000-0002-0058-8225, Fagan, C. C., Grandison, A. S., Sutton, R., Humphries, D. J., Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X, Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Givens, D. I. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2022) Effect of fat reformulated dairy food consumption on postprandial flow-mediated dilatation and cardiometabolic risk biomarkers compared with conventional dairy: a randomized, controlled trial. American Journal of Clinical Nutrition, 115 (3). pp. 679-693. ISSN 0002-9165 doi: https://doi.org/10.1093/ajcn/nqab428

Kliem, K. E. ORCID: https://orcid.org/0000-0002-0058-8225, Humphries, D. J., Markey, O., Vasilopoulou, D., Fagan, C. C., Grandison, A. S., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X, Givens, I. D. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2019) Food chain approach to lowering the saturated fat of milk and dairy products. International Journal of Dairy Technology, 72 (1). pp. 100-109. ISSN 1364-727X doi: https://doi.org/10.1111/1471-0307.12564

Markey, O., Souroullas, K., Fagan, C. C., Kliem, K. E. ORCID: https://orcid.org/0000-0002-0058-8225, Vasilopoulou, D., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Humphries, D. J., Grandison, A. S., Givens, D. I., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Methven, L. (2017) Consumer acceptance of dairy products with a saturated fatty acid-reduced, monounsaturated fatty acid-enriched content. Journal of Dairy Science, 100 (10). pp. 7953-7966. ISSN 0022-0302 doi: https://doi.org/10.3168/jds.2016-12057

Markey, O., Vasilopoulou, D., Givens, I. and Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2014) Dairy and cardiovascular health: friend or foe? Nutrition Bulletin, 39 (2). pp. 161-171. ISSN 1467-3010 doi: https://doi.org/10.1111/nbu.12086

Lamarche, B., Givens, D. I., Soedamah-Muthu, S., Krauss, R. M., Jakobsen, M. U., Bischoff-Ferrari, H. A., Pan, A. and Després, J. (2016) Does milk consumption contribute to cardiometabolic health and overall diet quality? Canadian Journal of Cardiology, 32 (8). pp. 1026-1032. ISSN 0828-282X doi: https://doi.org/10.1016/j.cjca.2015.12.033

Hobbs, D. A., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Givens, I. D. (2015) Dairy products: their role in the diet and effects on cardiovascular disease. In: Watson, R. R. and De Meester, F. (eds.) Handbook of Lipids in Human Function: Fatty Acids. AOCS Press, Oxford, pp. 111-130. ISBN 9781630670368

Givens, I. (2015) Manipulation of lipids in animal-derived foods: can it contribute to public health nutrition? European Journal of Lipid Science and Technology, 117 (9). pp. 1306-1316. ISSN 1438-9312 doi: https://doi.org/10.1002/ejlt.201400427

Molecular bases of tick-borne flavivirus transmission

Gritsun, D. J., Jones, I. M. ORCID: https://orcid.org/0000-0002-7738-2516, Gould, E. A. and Gritsun, T. S. (2014) Molecular archaeology of Flaviviridae untranslated regions: duplicated RNA structures in the replication enhancer of flaviviruses and pestiviruses emerged via convergent evolution. PloS one, 9 (3). e92056. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0092056

Neural underpinnings of emotional responding and regulation: antecedents and correlates

Barry, T. J., Murray, L., Fearon, P., Moutsiana, C., Johnstone, T. and Halligan, S. (2017) Amygdala volume and hypothalamic-pituitary-adrenal axis reactivity to social stress. Psychoneuroendocrinology, 85. pp. 96-99. ISSN 1873-3360 doi: https://doi.org/10.1016/j.psyneuen.2017.07.487

Barry, T. J., Murray, L., Fearon, R. M. P., Moutsiana, C., Cooper, P., Goodyer, I. M., Herbert, J. and Halligan, S. L. (2015) Maternal postnatal depression predicts altered offspring biological stress reactivity in adulthood. Psychoneuroendocrinology, 52. pp. 251-60. ISSN 1873-3360 doi: https://doi.org/10.1016/j.psyneuen.2014.12.003

Macdonald, B., Murray, L., Moutsiana, C., Fearon, P., Cooper, P. J., Halligan, S. L. and Johnstone, T. (2016) Altered engagement of autobiographical memory networks in adult offspring of postnatally depressed mothers. Biological Psychology, 118. pp. 147-153. ISSN 0301-0511 doi: https://doi.org/10.1016/j.biopsycho.2016.05.006

Prenatal and Infancy Origins of Biological and Social-Cognitive Processes in Disruptive Problems in Children Aged 7-9 Years

Obando, D., Hill, J., Sharp, H., Pickles, A., Fisher, L. and Wright, N. (2022) Synergy between callous-unemotional traits and aggression in preschool children: cross-informant and cross-cultural replication in the UK Wirral Child Health and Development Study, and the Colombian La Sabana Parent-Child Study. Development and Psychopathology, 34 (3). pp. 1079-1087. ISSN 1469-2198 doi: https://doi.org/10.1017/S0954579420002114

Bedford, R., Carter Leno, V., Wright, N., Bluett-Duncan, M., Smith, T. J., Anzures, G., Pickles, A., Sharp, H. and Hill, J. (2021) Emotion recognition performance in children with callous unemotional traits is modulated by co-occurring autistic traits. Journal of Clinical Child and Adolescent Psychology, 50 (6). pp. 811-827. ISSN 1537-4424 doi: https://doi.org/10.1080/15374416.2020.1833338

Wright, N., Hill, J., Pickles, A. and Sharp, H. (2019) Callous-unemotional traits, low cortisol reactivity and physical aggression in children: findings from the Wirral Child Health and Development Study. Translational Psychiatry, 9. 79. ISSN 2158-3188 doi: https://doi.org/10.1038/s41398-019-0406-9

Hill, J., Pickles, A., Wright, N., Braithwaite, E. and Sharp, H. (2019) Predictions of children’s emotionality from evolutionary and epigenetic hypotheses. Scientific Reports, 9. 2519. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-019-39513-7

Protein sumoylation in platelets: a potential new signalling paradigm in the control of haemostasis and thrombosis

Flora, G. D., Sahli, K. A., Sasikumar, P., Holbrook, L.-M., Stainer, A. R., Alouda, S. K., Crescente, M., Sage, T., Unsworth, A. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2019) Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis. Scientific Reports, 9 (1). 17210. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-019-53218-x

Holbrook, L.-M., Keeton, S. J., Sasikumar, P., Nock, S., Gelzinis, J., Brunt, E., Ryan, S., Pantos, M. M., Verbetsky, C. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Kennedy, D. R. (2021) Zafirlukast is a broad-spectrum thiol isomerase inhibitor that inhibits thrombosis without altering bleeding times. British Journal of Pharmacology, 178 (3). pp. 550-563. ISSN 1476-5381 doi: https://doi.org/10.1111/bph.15291

Reducing saturated fatty acids in the food chain thorugh alteration of milk fat composition DRINC.

Lamarche, B., Givens, D. I., Soedamah-Muthu, S., Krauss, R. M., Jakobsen, M. U., Bischoff-Ferrari, H. A., Pan, A. and Després, J. (2016) Does milk consumption contribute to cardiometabolic health and overall diet quality? Canadian Journal of Cardiology, 32 (8). pp. 1026-1032. ISSN 0828-282X doi: https://doi.org/10.1016/j.cjca.2015.12.033

Hobbs, D. A., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Givens, I. D. (2015) Dairy products: their role in the diet and effects on cardiovascular disease. In: Watson, R. R. and De Meester, F. (eds.) Handbook of Lipids in Human Function: Fatty Acids. AOCS Press, Oxford, pp. 111-130. ISBN 9781630670368

Reducing saturated fatty acids in the food chain through alteration of milk fat composition

Givens, I. (2015) Manipulation of lipids in animal-derived foods: can it contribute to public health nutrition? European Journal of Lipid Science and Technology, 117 (9). pp. 1306-1316. ISSN 1438-9312 doi: https://doi.org/10.1002/ejlt.201400427

Reward and empathy in autism - MRC EXTENSION

Thompson, N. M., Uusberg, A., Gross, J. J. and Chakrabarti, B. ORCID: https://orcid.org/0000-0002-6649-7895 (2019) Empathy and emotion regulation: an integrative account. In: Emotion and Cognition. Progress in Brain Research, 247. Elsevier, pp. 273-304. doi: https://doi.org/10.1016/bs.pbr.2019.03.024

Neufeld, J., Hsu, C.-T. and Chakrabarti, B. ORCID: https://orcid.org/0000-0002-6649-7895 (2019) Atypical reward-driven modulation of mimicry-related neural activity in autism. Frontiers in Psychiatry, 10. 327. ISSN 1664-0640 doi: https://doi.org/10.3389/fpsyt.2019.00327

Hedger, N., Haffey, A., McSorley, E. and Chakrabarti, B. ORCID: https://orcid.org/0000-0002-6649-7895 (2018) Empathy modulates the temporal structure of social attention. Proceedings of the Royal Society B: Biological Sciences, 285 (1893). 20181716. ISSN 0962-8452 doi: https://doi.org/10.1098/rspb.2018.1716

Hsu, C.-T., Neufeld, J. and Chakrabarti, B. ORCID: https://orcid.org/0000-0002-6649-7895 (2018) Reduced reward-related neural response to mimicry in individuals with autism. The European Journal of Neuroscience, 47 (6). pp. 610-618. ISSN 0953-816X doi: https://doi.org/10.1111/ejn.13620

Rudra, A., Belmonte, M. K., Soni, P. K., Banerjee, S., Mukerji, S. and Chakrabarti, B. ORCID: https://orcid.org/0000-0002-6649-7895 (2017) Prevalence of autism spectrum disorder and autistic symptoms in a school-based cohort of children in Kolkata, India. Autism Research, 10 (10). pp. 1597-1605. ISSN 1939-3806 doi: https://doi.org/10.1002/aur.1812

Chakrabarti, B. ORCID: https://orcid.org/0000-0002-6649-7895, Haffey, A., Canzano, L., Taylor, C. P. and McSorley, E. (2017) Individual differences in responsivity to social rewards: insights from two eye-tracking tasks. PLoS ONE, 12 (10). e0185146. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0185146

Winkielman, P., Carr, E. W., Chakrabarti, B. ORCID: https://orcid.org/0000-0002-6649-7895, Hofree, G. and Kavanagh, L. C. (2016) Mimicry, emotion, and social context: insights from typical and atypical humans, robots, and androids. In: Hess, U. and Fischer, A. (eds.) Emotional Mimicry in Social Context. Studies in Emotion and Social Interaction. Cambridge University Press, Cambridge, UK, pp. 162-191. ISBN 9781107064478

Neufeld, J. and Chakrabarti, B. ORCID: https://orcid.org/0000-0002-6649-7895 (2016) Empathy modulates the rewarding effect of mimicry. Scientific Reports, 6. 27751. ISSN 2045-2322 doi: https://doi.org/10.1038/srep27751

Studentship DTG Competition 2011

Thompson, N. M., van Reekum, C. M. ORCID: https://orcid.org/0000-0002-1516-1101 and Chakrabarti, B. ORCID: https://orcid.org/0000-0002-6649-7895 (2023) Emotion dysregulation modulates visual perspective taking and spontaneous facial mimicry. Emotion. ISSN 1931-1516 doi: https://doi.org/10.1037/emo0001254 (In Press)

Rayson, H., Bonaiuto, J. J., Ferrari, P. F., Chakrabarti, B. ORCID: https://orcid.org/0000-0002-6649-7895 and Murray, L. (2019) Building blocks of joint attention: early sensitivity to having one’s own gaze followed. Developmental Cognitive Neuroscience, 37. 100631. ISSN 1878-9307 doi: https://doi.org/10.1016/j.dcn.2019.100631

McSorley, E., Morriss, J. and Van Reekum, C. ORCID: https://orcid.org/0000-0002-1516-1101 (2017) Eye spy with my little eye: motivational relevance of visual stimuli guide eye-movements at different processing stages. Biological Psychology, 123. pp. 8-14. ISSN 0301-0511 doi: https://doi.org/10.1016/j.biopsycho.2016.11.008

Morriss, J., Henne, B. and Van Reekum, C. M. ORCID: https://orcid.org/0000-0002-1516-1101 (2016) What is going on around here? Intolerance of uncertainty predicts threat generalization. PLoS ONE. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0154494

Morriss, J., Christakou, A. ORCID: https://orcid.org/0000-0002-4267-3436 and Van Reekum, C. M. ORCID: https://orcid.org/0000-0002-1516-1101 (2015) Intolerance of uncertainty predicts fear extinction in amygdala-ventromedial prefrontal cortical circuitry. Biology of Mood & Anxiety Disorders, 5 (1). 4. ISSN 2045-5380 doi: https://doi.org/10.1186/s13587-015-0019-8

Study of the role of gap junctions and connexin hemichannels in the control of platlet function, haemostasis and thrombosis

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sage, T., Rana, R. H., Schenk, M. P., Ali, M. S., Unsworth, A. J., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Stainer, A. R., Kriek, N. K., Moraes, L. A. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) EphB2 regulates contact-dependent and independent signalling to control platelet function. Blood, 125 (4). pp. 720-730. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2014-06-585083

Study of the role of secreted platelet thiol isomerases in the regulation of platelet function, haemostasis and thrombosis

Flora, G. D., Sahli, K. A., Sasikumar, P., Holbrook, L.-M., Stainer, A. R., Alouda, S. K., Crescente, M., Sage, T., Unsworth, A. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2019) Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis. Scientific Reports, 9 (1). 17210. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-019-53218-x

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Roweth, H., Ali, M., Unsworth, A., Stainer, A., Flora, G., Crescente, M., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Moraes, L. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) Pharmacological actions of nobiletin in the modulation of platelet function. British Journal of Pharmacology, 172 (16). pp. 4133-4145. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.13191

Holbrook, L.-M., Keeton, S. J., Sasikumar, P., Nock, S., Gelzinis, J., Brunt, E., Ryan, S., Pantos, M. M., Verbetsky, C. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Kennedy, D. R. (2021) Zafirlukast is a broad-spectrum thiol isomerase inhibitor that inhibits thrombosis without altering bleeding times. British Journal of Pharmacology, 178 (3). pp. 550-563. ISSN 1476-5381 doi: https://doi.org/10.1111/bph.15291

Fuentos, E., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Holbrook, L. M. and Palomo, I. (2018) NADPH oxidase 2 (NOX2): a key target of oxidative stress-mediated platelet activation and thrombosis. Trends in Cardiovascular Medicine, 28 (7). pp. 429-434. ISSN 1050-1738 doi: https://doi.org/10.1016/j.tcm.2018.03.001

Simoes Gaspar, R. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Thiol isomerases orchestrate thrombosis and haemostasis. Antioxidants & Redox Signaling, 35 (13). ISSN 1523-0864 doi: https://doi.org/10.1089/ars.2021.0086

Gaspar, R. S., Mansilla, S., Vieira, V. A., da Silva, L. B., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Castro, L., Trostchansky, A. and de A. Paes, A. M. (2021) The protein disulphide isomerase inhibitor CxxCpep modulates oxidative burst and mitochondrial function in platelets. Free Radical Biology and Medicine, 172. pp. 668-674. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2021.07.011

Simoes Gaspar, R., Sage, T., Little, G., Kriek, N., Pula, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Protein disulphide isomerase and NADPH oxidase 1 cooperate to control platelet function and are associated with cardiometabolic disease risk factors. Antioxidants, 10 (3). 497. ISSN 2076-3921 doi: https://doi.org/10.3390/antiox10030497

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sage, T., Rana, R. H., Schenk, M. P., Ali, M. S., Unsworth, A. J., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Stainer, A. R., Kriek, N. K., Moraes, L. A. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) EphB2 regulates contact-dependent and independent signalling to control platelet function. Blood, 125 (4). pp. 720-730. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2014-06-585083

The Treatment of Child Anxiety Disorders via Guided CBT Self-Help: A Randomised Controlled Trial - MRC EXTENSION

Thirlwall, K., Cooper, P. and Creswell, C. (2017) Guided parent delivered cognitive behavioural therapy for childhood anxiety: predictors of treatment response. Journal of Anxiety Disorders, 45. pp. 43-48. ISSN 0887-6185 doi: https://doi.org/10.1016/j.janxdis.2016.11.003

The identification of the disulphide bonds in HIV gp120 whose reduction is required for cell entry and their manipulation for immunogen design

Holbrook, L.-M., Kwong, L.-S., Metcalfe, C. L., Fenouillet, E., Jones, I. M. ORCID: https://orcid.org/0000-0002-7738-2516 and Barclay, A. N. (2016) OX133, a monoclonal antibody recognizing protein-bound N-ethylmaleimide for the identification of reduced disulfide bonds in proteins. mAbs, 8 (4). pp. 672-677. ISSN 1942-0862 doi: https://doi.org/10.1080/19420862.2016.1152443

The modulation of catecholamine-thiol adduct-induced neuronal injury by flavonoids and their metabolites

Vauzour, D., Pinto, J. T., Cooper, A. J. L. and Spencer, J. P. E. (2014) The neurotoxicity of 5-S-cysteinyldopamine is mediated by the early activation of ERK1/2 followed by the subsequent activation of ASK1/JNK1/2 pro-apoptotic signalling. Biochemical Journal, 463 (1). pp. 41-52. ISSN 0264-6021 doi: https://doi.org/10.1042/BJ20131519

The physiological importance and integration of receptor-mediated inhibitory mechanisms in platelets

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sage, T., Rana, R. H., Schenk, M. P., Ali, M. S., Unsworth, A. J., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Stainer, A. R., Kriek, N. K., Moraes, L. A. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) EphB2 regulates contact-dependent and independent signalling to control platelet function. Blood, 125 (4). pp. 720-730. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2014-06-585083

Unsworth, A. J., Flora, G. D., Sasikumar, P., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Kriek, N., Crescente, M. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2017) RXR ligands negatively regulate thrombosis and hemostasis. Arteriosclerosis Thrombosis and Vascular Biology, 37 (5). pp. 812-822. ISSN 1524-4636 doi: https://doi.org/10.1161/ATVBAHA.117.309207

The physiological importance and integration of receptor-mediated inhibitory mechanisms in platelets in health and disease

Flora, G. D., Sahli, K. A., Sasikumar, P., Holbrook, L.-M., Stainer, A. R., Alouda, S. K., Crescente, M., Sage, T., Unsworth, A. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2019) Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis. Scientific Reports, 9 (1). 17210. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-019-53218-x

Fuentos, E., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Holbrook, L. M. and Palomo, I. (2018) NADPH oxidase 2 (NOX2): a key target of oxidative stress-mediated platelet activation and thrombosis. Trends in Cardiovascular Medicine, 28 (7). pp. 429-434. ISSN 1050-1738 doi: https://doi.org/10.1016/j.tcm.2018.03.001

Simoes Gaspar, R. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Thiol isomerases orchestrate thrombosis and haemostasis. Antioxidants & Redox Signaling, 35 (13). ISSN 1523-0864 doi: https://doi.org/10.1089/ars.2021.0086

Gaspar, R. S., Mansilla, S., Vieira, V. A., da Silva, L. B., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Castro, L., Trostchansky, A. and de A. Paes, A. M. (2021) The protein disulphide isomerase inhibitor CxxCpep modulates oxidative burst and mitochondrial function in platelets. Free Radical Biology and Medicine, 172. pp. 668-674. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2021.07.011

Simoes Gaspar, R., Sage, T., Little, G., Kriek, N., Pula, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Protein disulphide isomerase and NADPH oxidase 1 cooperate to control platelet function and are associated with cardiometabolic disease risk factors. Antioxidants, 10 (3). 497. ISSN 2076-3921 doi: https://doi.org/10.3390/antiox10030497

Unsworth, A. J., Flora, G. D., Sasikumar, P., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Kriek, N., Crescente, M. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2017) RXR ligands negatively regulate thrombosis and hemostasis. Arteriosclerosis Thrombosis and Vascular Biology, 37 (5). pp. 812-822. ISSN 1524-4636 doi: https://doi.org/10.1161/ATVBAHA.117.309207

Therapeutic corneal stem cell delivery using a bioadhesive in situ gelling system

The University of Newcastle Upon Tyne , Newcastle upon Tyne ( GB (2020) Transport of cells in hydrogels. US 10,655,120 B2. doi: US 10,655,120 B2

Treatment of Child Anxiety Disorder in the Context of Maternal Anxiety: A Randomised Controlled Trial

Halldorsson, B., Castelijn, S. and Creswell, C. (2019) Are children with social anxiety disorder more likely than children with other anxiety disorders to anticipate poor social performance and reflect negatively on their performance? Journal of Affective Disorders, 245. pp. 561-568. ISSN 0165-0327 doi: https://doi.org/10.1016/j.jad.2018.11.021

Typical and atypical ocular accommodation and convergence characteristics and relationships over the life span

Toor, S., Horwood, A. ORCID: https://orcid.org/0000-0003-0886-9686 and Riddell, P. ORCID: https://orcid.org/0000-0002-4916-2057 (2019) The effect of asymmetrical accommodation on anisometropic amblyopia treatment outcomes. Journal of AAPOS, 23 (4). 203.e1-203.e5. ISSN 1091-8531 doi: https://doi.org/10.1016/j.jaapos.2019.05.010

Toor, S., Horwood, A. M. ORCID: https://orcid.org/0000-0003-0886-9686 and Riddell, P. ORCID: https://orcid.org/0000-0002-4916-2057 (2018) Asymmetrical accommodation in hyperopic anisometropic amblyopia. British Journal of Ophthalmology, 102 (6). pp. 772-778. ISSN 0007-1161 doi: https://doi.org/10.1136/bjophthalmol-2017-310282

Brodsky, M. C., Horwood, A. M. ORCID: https://orcid.org/0000-0003-0886-9686 and Riddell, P. M. ORCID: https://orcid.org/0000-0002-4916-2057 (2015) Intermittent exotropia: are we underminusing by not overminusing? Journal of the American Association of Pediatric Ophthalmology and Strabismus, 15 (5). pp. 397-398. ISSN 1091-8531 doi: https://doi.org/10.1016/j.jaapos.2015.05.011

Horwood, A. M. ORCID: https://orcid.org/0000-0003-0886-9686, Toor, S. and Riddell, P. M. ORCID: https://orcid.org/0000-0002-4916-2057 (2015) Convergence and accommodation development is pre-programmed in premature infants. Investigative Ophthalmology & Visual Science, 56. pp. 5370-5380. ISSN 0146-0404 doi: https://doi.org/10.1167/iovs.14-15358

Horwood, A. ORCID: https://orcid.org/0000-0003-0886-9686 and Toor, S. (2014) Clinical test responses to different orthoptic exercise regimes in typical young adults. Ophthalmic and Physiological Optics, 34 (2). pp. 250-262. ISSN 1475-1313 doi: https://doi.org/10.1111/opo.12109

Horwood, A. M. ORCID: https://orcid.org/0000-0003-0886-9686, Toor, S. and Riddell, P. M. ORCID: https://orcid.org/0000-0002-4916-2057 (2014) Screening for convergence insufficiency using the CISS is not indicated in young adults. British Journal of Ophthalmology, 98 (5). pp. 679-683. ISSN 1468-2079 doi: https://doi.org/10.1136/bjophthalmol-2013-304533

Horwood, A. M. ORCID: https://orcid.org/0000-0003-0886-9686, Toor, S. S. and Riddell, P. M. ORCID: https://orcid.org/0000-0002-4916-2057 (2014) Change in convergence and accommodation after two weeks of eye exercises in typical young adults. Journal of American Association for Pediatric Ophthalmology and Strabismus, 18 (2). pp. 162-168. ISSN 1091-8531 doi: https://doi.org/10.1016/j.jaapos.2013.11.008

Horwood, A. M. ORCID: https://orcid.org/0000-0003-0886-9686 and Riddell, P. M. ORCID: https://orcid.org/0000-0002-4916-2057 (2013) The clinical near gradient stimulus AC/A ratio correlates better with the response CA/C ratio than with the response AC/A ratio. Strabismus, 21 (2). pp. 140-144. ISSN 0927-3972 doi: https://doi.org/10.3109/09273972.2013.786741

Horwood, A. ORCID: https://orcid.org/0000-0003-0886-9686 (2016) Convergence accommodation in orthoptic practice. British & Irish Orthoptic Journal, 13. pp. 2-8. ISSN 1743-9868 doi: https://doi.org/10.22599/bioj.95

Using FMRI and TMS to probe the functional connectivity of prefrontal cortex and amygdala in top-down regulation of emotion

Macdonald, B., Murray, L., Moutsiana, C., Fearon, P., Cooper, P. J., Halligan, S. L. and Johnstone, T. (2016) Altered engagement of autobiographical memory networks in adult offspring of postnatally depressed mothers. Biological Psychology, 118. pp. 147-153. ISSN 0301-0511 doi: https://doi.org/10.1016/j.biopsycho.2016.05.006

Using Surrogate Endpoints for Decision-Making in Adaptive Seamless Designs

Kunz, C. U., Stallard, N., Parsons, N., Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X and Friede, T. (2017) Blinded versus unblinded estimation of a correlation coefficient to inform interim design adaptations. Biometrical Journal, 59 (2). pp. 344-357. ISSN 0323-3847 doi: https://doi.org/10.1002/bimj.201500233

Stallard, N., Kunz, C. U., Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X, Parsons, N. and Friede, T. (2015) Flexible selection of a single treatment incorporating short-term endpoint information in a phase II/III clinical trial. Statistics in Medicine, 34 (23). pp. 3104-3115. ISSN 0277-6715 doi: https://doi.org/10.1002/sim.6567

Kunz, C. U., Friede, T., Parsons, N., Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X and Stallard, N. (2015) A comparison of methods for treatment selection in seamless phase II/III clinical trials incorporating information on short-term endpoints. Journal of Biopharmaceutical Statistics, 25 (1). pp. 170-189. ISSN 1054-3406 doi: https://doi.org/10.1080/10543406.2013.840646

Kunz, C. U., Friede, T., Parsons, N., Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X and Stallard, N. (2014) Data-driven treatment selection for seamless phase II/III trials incorporating early-outcome data. Pharmaceutical Statistics, 13 (4). pp. 238-246. ISSN 1539-1612 doi: https://doi.org/10.1002/pst.1619

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