A

Aitken, L. S., Hammond, L. E., Sundaram, R., Shankland, K., Brown, G. D. and Cobb, A. J. A. (2015) Asymmetric cyclopropanation of conjugated cyanosulfones using a novel cupreine organocatalyst: rapid access to d3-amino acids. Chemical Communications, 51 (70). pp. 13558-13561. ISSN 1359-7345 doi: 10.1039/c5cc05158d

Al-Ani, W., Shankland, K. and Cobb, A. J. A. (2016) Asymmetric organocatalytic synthesis of cyclopentane γ-nitroketones. Synlett, 27 (1). pp. 17-20. ISSN 0936-5214 doi: 10.1055/s-0035-1560504

B

Bajaj, N., Hart, L. R., Greenland, B. W. and Hayes, W. (2013) Urea organogelators: synthesis and properties. Macromolecular Symposia, 329 (1). pp. 118-124. ISSN 1022-1360 doi: 10.1002/masy.201200103

Baksh, M. F. and Kelly, P. (2008) Statistical methods for examining genetic influences of resistance to anti-epileptic drugs. Expert Review of Clinical Pharmacology, 1 (1). pp. 137-144. ISSN 1751-2433 doi: 10.1586/17512433.1.1.137

Bauer, J. and Osborn, H. M. I. (2015) Sialic acids in biological and therapeutic processes: opportunities and challenges. Future Medicinal Chemistry, 7 (16). pp. 2285-2299. ISSN 1756-8927 doi: 10.4155/fmc.15.135

Bauer, J., Stiller, J., Marques-Lopez, E., Strohfeldt, K. A., Christmann, M. and Strohmann , C. (2010) Silyl-Modified Analogues of 2-Tritylpyrrolidine: Synthesis and Applications in Asymmetric Organocatalysis. Chemistry - A European Journal, 16 (42). pp. 12553-12558. ISSN 0947-6539 doi: 10.1002/chem.201002166

Benning, R. K., Osborn, H. M. I. and Turkson, A. (2011) Regioselective Beckmann rearrangements of furanoside and pyranoside-derived oximes. Tetrahedron: Asymmetry, 22 (1). pp. 109-116. ISSN 0957-4166 doi: 10.1016/j.tetasy.2010.11.031

Bonjoch, J., Drew, M. G.B., Gonzalez, A., Greco, F., Jawaid, S., Osborn, H. M. I., Williams, N. A.O. and Yaqoob, P. (2008) Synthesis and evaluation of novel boron-containing complexes of potential use for the selective treatment of malignant melanoma. Journal of Medicinal Chemistry, 51 (20). pp. 6604-6608. ISSN 0022-2623 doi: 10.1021/jm8007745

Bovill, R., Evans, P. G., Howse, G. L. and Osborn, H. M. I. (2016) Synthesis and biological analysis of novel glycoside derivatives of L-AEP, as targeted antibacterial agents. Bioorganic & Medicinal Chemistry Letters, 26 (15). pp. 3774-3779. ISSN 0960-894X doi: 10.1016/j.bmcl.2016.05.052

Brazier, J. A., Shah, A. and Brown, G. D. (2012) I-Motif formation in gene promoters: unusually stable formation in sequences complementary to known G-quadruplexes. Chemical Communication, 48 (87). pp. 10739-10741. ISSN 1359-7345 doi: 10.1039/C2CC30863K

Brazier, J. A., Shibata, T., Townsley, J., Taylor, B. F., Frary, E., Williams, N. H. and Williams, D. M. (2005) Amino-functionalized DNA: the properties of C5-amino-alkyl substituted 2′-deoxyuridines and their application in DNA triplex formation. Nucleic Acids Research, 33 (4). pp. 1362-1371. ISSN 1362-4962 doi: 10.1093/nar/gki254

Bryant, L. A., Fanelli, R. and Cobb, A. J. A. (2016) Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts. Beilstein Journal of Organic Chemistry, 12. pp. 429-443. ISSN 1860-5397 doi: 10.3762/bjoc.12.46

Burland, P. A., Coisson, D. and Osborn, H. M. I. (2010) Rapid synthesis of carbohydrate derivatives, including mimetics of c-linked disaccharides and c-Linked aza disaccharides, using the Hetero-Diels−Alder Reaction. Journal of Organic Chemistry, 75 (21). pp. 7210-7218. ISSN 0022-3263 doi: 10.1021/jo101219w

Burland, P. A., Osborn, H. M. I. and Turkson, A. (2011) Synthesis and glycosidase inhibitory profiles of functionalised morpholines and oxazepanes. Bioorganic & Medicinal Chemistry, 19 (18). pp. 5679-5692. ISSN 0968-0896 doi: 10.1016/j.bmc.2011.07.019

C

Carlescu, I., Osborn, H. M.I., Desbrieres, J., Scutaru, D. and Popa, M. (2010) Synthesis of poly(aspartimide)-based bio-glycoconjugates. Carbohydrate Research, 345 (1). pp. 33-40. ISSN 0008-6215 doi: 10.1016/j.carres.2009.08.034

Chen, L., Willcock, H., Wedge, C. J., Hartl, F., Colquhoun, H. M. and Greenland, B. W. (2016) Efficient access to conjugated 4,4’-bipyridinium oligomers using the Zincke reaction: synthesis, spectroscopic and electrochemical properties. Organic and Biomolecular Chemistry, 14 (3). pp. 980-988. ISSN 1477-0520 doi: 10.1039/c5ob02211h

Cheng, G., Greenland, B. W., Lampard, C., Williams, N., Bahra, M. S. and Hayes, W. (2013) Lightly branched comb polyesters: application in fast drying solvent-borne coating formulations. Reactive & Functional Polymers, 73 (4). pp. 619-623. ISSN 1381-5148 doi: 10.1016/j.reactfunctpolym.2013.01.008

Cheng, G., Greenland, B. W., Lampard, C., Williams, N., Barhra, M. S. and Hayes, W. (2013) Synthesis of novel hyperbranched polymers featuring oxazoline linear units and their application in fast-drying solvent-borne coating formulations. Journal of Polymer Science Part A: Polymer Chemistry, 51 (18). pp. 3964-3974. ISSN 1099-0518 doi: 10.1002/pola.26807

Cobb, A. (2011) General aspects of organocatalytic cyclizations. In: Mahrwald, R. (ed.) Enantioselective Organocatalyzed Reactions II: Asymmetric C-C Bond Formation Processes. Springer, pp. 1-40. ISBN 9789048138661

Cobb, A., Arezki, N., Dell'Isola, A. and Aitken, L. (2013) Asymmetric organocatalysis and the nitro group functionality. Synthesis-Stuttgart, 45 (19). pp. 2627-2648. ISSN 0039-7881 doi: 10.1055/s-0033-1338522

D

Dell'Isola, A., McLachlan, M. M. W., Neuman, B. W., Al-Mullah, H. M. N., Binks, A. W. D., Elvidge, W., Shankland, K. and Cobb, A. J. A. (2014) Synthesis and antiviral properties of spirocyclic [1,2,3]-triazolooxazine nucleosides. Chemistry- A European Journal, 20 (37). pp. 11685-11689. ISSN 0947-6539 doi: 10.1002/chem.201403560

E

Ellis, D., Norman, S. E. and Osborn, H. M. I. (2008) Synthesis of S-linked carbohydrate analogues via a Ferrier reaction. Tetrahedron, 64 (12). pp. 2832-2854. ISSN 0040-4020 doi: 10.1016/j.tet.2008.01.042

F

Fante, C., Eldar-Boock, A., Satchi-Fainaro, R., Osborn, H. M. I. and Greco, F. (2011) Synthesis and biological evaluation of a polyglutamic acid-dopamine conjugate: a new antiangiogenic agent. Journal of Medicinal Chemistry, 54 (14). pp. 5255-5259. ISSN 0022-2623 doi: 10.1021/jm200382r

Fern, S. E., Heath, P. and Cobb, A. J. A. (2011) Aldol reaction of butane-2,3-diacetal protected methyl glycerate. Tetrahedron: Asymmetry, 22 (2). pp. 149-152. ISSN 0957-4166 doi: 10.1016/j.tetasy.2011.01.004

G

Gadd, A. J. R., Greco, F., Cobb, A. J. A. and Edwards, A. D. (2015) Targeted activation of toll-like receptors: conjugation of a toll-like receptor 7 agonist to a monoclonal antibody maintains antigen binding and specificity. Bioconjugate Chemistry, 26 (8). pp. 1743-1752. ISSN 1043-1802 doi: 10.1021/acs.bioconjchem.5b00302

Gaynor, J. W., Brazier, J. and Cosstick, R. (2007) Synthesis of 3 '-S-phosphorothiolate oligonucleotides for their potential use in RNA interference. Nucleosides Nucleotides & Nucleic Acids, 26 (6-7). pp. 709-712. ISSN 1525-7770 doi: 10.1080/15257770701490753

Greenland, B. W. and Hayes, W. (2015) Donor-acceptor π−π stacking interactions: from small molecule complexes to healable supramolecular polymer networks. In: Supramolecular polymer networks and gels. Advances in Polymer Science. Springer, pp. 143-166.

Greenland, B. W. and Hayes, W. (2013) Healable polymeric materials. In: Greenland, B. W. and Hayes, W. (eds.) Healable polymer systems. Royal Society of Chemistry, London, pp. 1-15. ISBN 9781849736268 doi: 10.1039/9781849737470-00001

Greenland, B. W., Bird, M. B., Burattini, S., Cramer, R., O'Reilly, R. K., Patterson, J. P., Hayes, W., Cardin, C. J. and Colquhoun, H. M. (2013) Mutual binding of polymer end-groups by complementary π–π-stacking: a molecular “Roman Handshake”. Chemical Communications, 49 (5). pp. 454-456. ISSN 1359-7345 doi: 10.1039/C2CC35965K

Greenland, B. W., Fiore, G. L., Rowan, S. J. and Weder, C. (2013) Healable supramolecular polymeric materials. In: Hayes, W. and Greenland, B. W. (eds.) Healable Polymer Systems. Royal Society of Chemistry, Cambridge, pp. 92-125. ISBN 9781849736268 doi: 10.1039/9781849737470-00092

Gurung, S. P., Schwarz, C., Hall, J. P., Cardin, C. J. and Brazier, J. (2015) The importance of loop length on the stability of i-motif structures. Chemical Communications, 51 (26). pp. 5630-5632. ISSN 1359-7345 doi: 10.1039/C4CC07279K

H

Hall, J. P., Keane, P., Beer, H., Buchner, K., Winter, G., Sorensen, T., Cardin, D., Brazier, J. and Cardin, C. (2016) Delta chirality ruthenium ‘light-switch’ complexes can bind in the minor groove of DNA with five different binding modes. Nucleic Acids Research. ISSN 1362-4962 doi: 10.1093/nar/gkw753

Hall, J. P., Poynton, F. E., Keane, P. M., Gurung, S. P., Brazier, J. A., Cardin, D. J. , Winter, G., Gunnlaugsson, T., Sazanovich, I. V., Towrie, M., Cardin, C. J., Kelly, J. M. and Quinn, S. J. (2015) Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy. Nature Chemistry, 7. pp. 961-967. ISSN 1755-4330 doi: 10.1038/nchem.2369

Hart, L. R., Harries, J. L., Greenland, B. W., Colquhoun, H. M. and Hayes, W. (2013) Healable supramolecular polymers. Polymer Chemistry, 4. pp. 4860-4870. ISSN 1759-9954 doi: 10.1039/C3PY00081H

Hart, L. R., Hunter, J. H., Nguyen, N. A., Harries, J. L., Greenland, B. W., Mackay, M. E., Colquhoun, H. M. and Hayes, W. (2014) Multivalency in healable supramolecular polymers: the effect of supramolecular cross-link density on the mechanical properties and healing of noncovalent polymer networks. Polymer Chemistry, 5 (11). pp. 3680-3688. ISSN 1759-9954 doi: 10.1039/C4PY00292J

Hayes, W. and Greenland, B. W., eds. (2013) Healable Polymer Systems. Royal Society of Chemistry, Cambridge, pp165. ISBN 9781849736268

J

Jarvis, A. N., McClaren, A. B., Osborn, H. M. I. and Sweeney, J. (2013) Preparation and ring-opening reactions of N-diphenylphosphinyl vinyl aziridines. Beilstein Journal of Organic Chemistry, 9. pp. 852-859. ISSN 1860-5397 doi: 10.3762/bjoc.9.98

Jawaid, S., Khan, T. H., Osborn, H. M. I. and Williams, N. O. A. (2009) Tyrosinase activated melanoma prodrugs. Anti-cancer agents in medicinal chemistry, 9 (7). pp. 717-727. ISSN 1871-5206

K

Keane, P. M., Baptista, F. R., Gurung, S. P., Devereux, S. J., Sazanovich , I. V., Towrie, M., Brazier, J. A., Cardin, C. J., Kelly, J. M. and Quinn, S. J. (2016) Long-lived excited-state dynamics of i-motif structures probed by time-resolved infrared spectroscopy. ChemPhysChem, 17 (9). pp. 1281-1287. ISSN 1439-7641 doi: 10.1002/cphc.201501183

Kikuta, K., Piao, H., Brazier, J., Taniguchi, Y., Onizuka, K., Nagatsugi, F. and Sasaki, S. (2015) Stabilization of the i-motif structure by the intra-strand cross-link formation. Bioorganic & Medicinal Chemistry Letters, 25 (16). pp. 3307-3310. ISSN 0960-894X doi: 10.1016/j.bmcl.2015.05.064

Kolstoe, S. E., Mangione, P. P., Bellotti, V., Taylor, G. W., Tennent, G. A., Deroo, S., Morrison, A. J., Cobb, A. J. A., Coyne, A., McCammon, M. G., Warner, T. D., Mitchell, J., Gill, R., Smith, M. D., Ley, S. V., Robinson, S. P. and Pepys, M. B. (2010) Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Proceedings of the National Academy of Sciences of the United States of America, 107 (47). pp. 20483-20488. ISSN 0027-8424 doi: 10.1073/pnas.1008255107

M

MacDonald, J. P. , Parker, M. P., Greenland, B. W., Hermida-Merino, D., Hamley, I. W. and Shaver, M. P. (2015) Tuning thermal properties and microphase separation in aliphatic polyester ABA copolymers. Polymer Chemistry, 6 (9). pp. 1445-1453. ISSN 1759-9954 doi: 10.1039/c4py01459f

Murray, C. A., Cardin, C. J., Greenland, B. W., Swift, A. and Colquhoun, H. M. (2013) Pairwise assembly of organopalladium(II) units with cyanurato(3-) and trithiocyanurato(3-) ligands: formation of chiral Pd12, Pd10 and Pd9 cage-molecules. Inorganic Chemistry, 52 (18). pp. 10424-10430. ISSN 0020-1669 doi: 10.1021/ic401253q

N

Nodes, W. J., Shankland, K., Rajkumar, S. and Cobb, A. J. A. (2010) Asymmetric phase-transfer-catalyzed synthesis of five-membered cyclic gamma-Amino acid precursors. Synlett , 2010 (20). pp. 3011-3014. ISSN 1437-2096 doi: 10.1055/s-0030-1259050

Nodes, W., Nutt, D. R., Chippindale, A. M. and Cobb, A. J. A. (2009) Enantioselective Intramolecular Michael Addition of Nitronates onto Conjugated Esters: Access to Cyclic γ-Amino Acids with up to Three Stereocenters. Journal of the American Chemical Society, 131 (44). pp. 16016-16017. ISSN 0002-7863 doi: 10.1021/ja9070915

O

Olorunniji, F. J., McPherson, A. L., Pavlou, H. J., McIlwraith, M. J., Brazier, J., Cosstick, R. and Stark, W. M. (2015) Nicked-site substrates for a serine recombinase reveal enzyme–DNA communications and an essential tethering role of covalent enzyme–DNA linkages. Nucleic Acids Research, 43 (12). pp. 6134-6143. ISSN 1362-4962 doi: 10.1093/nar/gkv521

Osborn, H. M. I. and Turkson, A. (2009) Synthesis and NMR spectroscopic analysis of 3-nitro-pyranoside, 3-nitro-septanoside and 4-nitro-septanoside derivatives by condensation of the anion of nitromethane with glycoside. Tetrahedron Asymmetry, 20 (18). pp. 2162-2166. ISSN 0957-4166 doi: 10.1016/j.tetasy.2009.08.004

P

Parshotam, J. P., Brazier, J. A., Bovill, R. and Osborn, H. M. I. (2016) An efficient and rapid microwave-assisted synthesis of 1-acetyl-1H-indol-3-YL acetates. Current Microwave Chemistry, 3 (3). pp. 247-257. ISSN 2213-3364 doi: 10.2174/2213335603666160108001556

R

Rajkumar, S., Shankland, K., Brown, G. D. and Cobb, A. (2012) Organocatalytic enantioselective construction of nitrocyclohexanes containing multiple chiral centres via a cascade reaction. Chemical Science, 3. pp. 584-588. ISSN 1478-6524 doi: 10.1039/C1SC00592H

Rajkumar, S., Shankland, K., Goodman, J. M. and Cobb, A. J.A. (2013) Organocatalytic domino reaction of cyanosulfones: access to complex cyclohexane systems with quaternary carbon centers. Organic Letters, 15 (6). pp. 1386-1389. ISSN 1523-7060 doi: 10.1021/ol400356k

Rajora, A. K., Ravishankar, D., Osborn, H. M.I. and Greco, F. (2014) Impact of the enhanced permeability and retention (EPR) effect and cathepsins levels on the activity of polymer-drug conjugates. Polymers, 6 (8). pp. 2186-2220. ISSN 2073-4360 doi: 10.3390/polym6082186

Rangam, G., Schmitz, K.-M., Cobb, A. and Petersen-Mahrt, S. (2012) AID enzymatic activity is inversely proportional to the size of cytosine C5 orbital cloud. PloS ONE, 7 (8). e43279. ISSN 1932-6203 doi: 10.1371/journal.pone.0043279

Ravishankar, D., Corona, G., Hogan, S. M., Spencer, J. P. E., Greco, F. and Osborn, H. M. I. (2016) Thioflavones as novel neuroprotective agents. Bioorganic & Medicinal Chemistry. ISSN 0968-0896 doi: 10.1016/j.bmc.2016.09.006 (In Press)

Ravishankar, D., Watson, K. A., Greco, F. and Osborn, H. M. I. (2016) Novel synthesised flavone derivatives provide significant insight into the structural features required for enhanced anti-proliferative activity. RSC Advances, 6 (69). pp. 64544-64556. ISSN 2046-2069 doi: 10.1039/C6RA11041J

Ravishankar, D., Rajora, A., Greco, F. and Osborn, H. (2013) Flavonoids as prospective compounds for anti-cancer therapy. International Journal of Biochemistry and Cell Biology, 45 (12). pp. 2821-2831. ISSN 1878-5875 doi: 10.1016/j.biocel.2013.10.004

Ravishankar, D., Watson, K. A., Boateng, S. Y., Green, R. J., Greco, F. and Osborn, H. M.I. (2015) Exploring quercetin and luteolin derivatives as antiangiogenic agents. European Journal of Medicinal Chemistry, 97. pp. 259-274. ISSN 0223-5234 doi: 10.1016/j.ejmech.2015.04.056

S

Sarsam, S. W., Nutt, D. R., Strohfeldt, K. and Watson, K. A. (2011) Titanocene anticancer complexes and their binding mode of action to human serum albumin: a computational study. Metallomics, 3 (2). pp. 152-161. ISSN 1756-5901 doi: 10.1039/c0mt00041h

Shaikh, A. K., Cobb, A. J. A. and Varvounis, G. (2012) Mild and rapid method for the generation of ortho-(naphtho)-quinone methide intermediates. Organic Letters, 14 (2). pp. 584-587. ISSN 1523-7060 doi: 10.1021/ol203196n

Steinke, J. H. G., Greenland, B. W., Johns, S., Parker, M. P., Atkinson, R. C. J., Cade, I. A. and Trussell, S. J. (2014) Robust and operationally simple synthesis of Poly(bis(2,2,2- trifluoroethoxy) phosphazene) with controlled molecular weight, low PDI, and high conversion. ACS Macro Letters, 3. pp. 548-551. ISSN 2161-1653 doi: 10.1021/mz500199x

Strohfeldt, K. and Grant, D. T. (2010) A model for self-directed problem-based learning for renal therapeutics. American Journal of Pharmaceutical Education , 74 (9). Article 173.

Strohfeldt, K. and Khutoryanskaya, O. (2015) Using problem-based learning in a chemistry practical class for pharmacy students and engaging them with feedback. American Journal of Pharmaceutical Education, 79 (9). 141. ISSN 1553-6467 doi: 10.5688/ajpe799141

Strohfeldt, K. A. and Tacke, M. (2008) Bioorganometallic fulvene-derived titanocene anti-cancer drugs. Chemical Society Reviews, 37 (6). pp. 1174-1187. ISSN 0306-0012 doi: DOI:10.1039/b707310k

V

Vaiyapuri, R., Greenland, B., Colquhoun, H. M., Elliott, J. M. and Hayes, W. (2014) Evolution of supramolecular healable composites: a minireview. Polymer International, 63 (6). pp. 933-942. ISSN 0959-8103 doi: 10.1002/pi.4685

Vaiyapuri, R., Greenland, B. W., Colquhoun, H. M., Elliott, J. E. and Hayes, W. (2013) Molecular recognition between functionalized gold nanoparticles and healable, supramolecular polymer blends – a route to property enhancement. Polymer Chemistry, 4. pp. 4902-4909. ISSN 1759-9954 doi: 10.1039/c3py00086a

Vessieres, A., Plamont, M.-A., Cabestaing, C., Claffey, J., Dieckmann, S., Hogan, M., Mueller-Bunz, H., Strohfeldt, K. A. and Tacke, M. (2009) Proliferative and anti-proliferative effects of titanium- and iron-based metallocene anti-cancer drugs. Journal of Organometallic Chemistry , 694 (6). pp. 874-879. ISSN 0022-328X doi: 10.1016/j.jorganchem.2008.11.071