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Items where Division is "Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Medicinal Chemistry Research Group"

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Number of items at this level: 40.

2013

Bajaj, N., Hart, L. R., Greenland, B. W. and Hayes, W. (2013) Urea organogelators: synthesis and properties. Macromolecular Symposia, 329 (1). pp. 118-124. ISSN 1022-1360 doi: 10.1002/masy.201200103

Cheng, G., Greenland, B. W., Lampard, C., Williams, N., Bahra, M. S. and Hayes, W. (2013) Lightly branched comb polyesters: application in fast drying solvent-borne coating formulations. Reactive & Functional Polymers, 73 (4). pp. 619-623. ISSN 1381-5148 doi: 10.1016/j.reactfunctpolym.2013.01.008

Cheng, G., Greenland, B. W., Lampard, C., Williams, N., Barhra, M. S. and Hayes, W. (2013) Synthesis of novel hyperbranched polymers featuring oxazoline linear units and their application in fast-drying solvent-borne coating formulations. Journal of Polymer Science Part A: Polymer Chemistry, 51 (18). pp. 3964-3974. ISSN 1099-0518 doi: 10.1002/pola.26807

Cobb, A., Arezki, N., Dell'Isola, A. and Aitken, L. (2013) Asymmetric organocatalysis and the nitro group functionality. Synthesis-Stuttgart, 45 (19). pp. 2627-2648. ISSN 0039-7881 doi: 10.1055/s-0033-1338522

Greenland, B. W. and Hayes, W. (2013) Healable polymeric materials. In: Greenland, B. W. and Hayes, W. (eds.) Healable polymer systems. Royal Society of Chemistry, London, pp. 1-15. ISBN 9781849736268 doi: 10.1039/9781849737470-00001

Greenland, B. W., Bird, M. B., Burattini, S., Cramer, R., O'Reilly, R. K., Patterson, J. P., Hayes, W., Cardin, C. J. and Colquhoun, H. M. (2013) Mutual binding of polymer end-groups by complementary π–π-stacking: a molecular “Roman Handshake”. Chemical Communications, 49 (5). pp. 454-456. ISSN 1359-7345 doi: 10.1039/C2CC35965K

Greenland, B. W., Fiore, G. L., Rowan, S. J. and Weder, C. (2013) Healable supramolecular polymeric materials. In: Hayes, W. and Greenland, B. W. (eds.) Healable Polymer Systems. Royal Society of Chemistry, Cambridge, pp. 92-125. ISBN 9781849736268 doi: 10.1039/9781849737470-00092

Hart, L. R., Harries, J. L., Greenland, B. W., Colquhoun, H. M. and Hayes, W. (2013) Healable supramolecular polymers. Polymer Chemistry, 4. pp. 4860-4870. ISSN 1759-9954 doi: 10.1039/C3PY00081H

Hayes, W. and Greenland, B. W., eds. (2013) Healable Polymer Systems. Royal Society of Chemistry, Cambridge, pp165. ISBN 9781849736268

Jarvis, A. N., McClaren, A. B., Osborn, H. M. I. and Sweeney, J. (2013) Preparation and ring-opening reactions of N-diphenylphosphinyl vinyl aziridines. Beilstein Journal of Organic Chemistry, 9. pp. 852-859. ISSN 1860-5397 doi: 10.3762/bjoc.9.98

Murray, C. A., Cardin, C. J., Greenland, B. W., Swift, A. and Colquhoun, H. M. (2013) Pairwise assembly of organopalladium(II) units with cyanurato(3-) and trithiocyanurato(3-) ligands: formation of chiral Pd12, Pd10 and Pd9 cage-molecules. Inorganic Chemistry, 52 (18). pp. 10424-10430. ISSN 0020-1669 doi: 10.1021/ic401253q

Rajkumar, S., Shankland, K., Goodman, J. M. and Cobb, A. J.A. (2013) Organocatalytic domino reaction of cyanosulfones: access to complex cyclohexane systems with quaternary carbon centers. Organic Letters. ISSN 1523-7060 doi: 10.1021/ol400356k

Ravishankar, D., Rajora, A., Greco, F. and Osborn, H. (2013) Flavonoids as prospective compounds for anti-cancer therapy. International Journal of Biochemistry and Cell Biology, 45 (12). pp. 2821-2831. ISSN 1878-5875 doi: 10.1016/j.biocel.2013.10.004

Vaiyapuri, R., Greenland, B. W., Colquhoun, H. M., Elliott, J. E. and Hayes, W. (2013) Molecular recognition between functionalized gold nanoparticles and healable, supramolecular polymer blends – a route to property enhancement. Polymer Chemistry, 4. pp. 4902-4909. ISSN 1759-9954 doi: 10.1039/c3py00086a

2012

Brazier, J. A., Shah, A. and Brown, G. D. (2012) I-Motif formation in gene promoters: unusually stable formation in sequences complementary to known G-quadruplexes. Chemical Communication, 48 (87). pp. 10739-10741. ISSN 1359-7345 doi: 10.1039/C2CC30863K

Rajkumar, S., Shankland, K., Brown, G. D. and Cobb, A. (2012) Organocatalytic enantioselective construction of nitrocyclohexanes containing multiple chiral centres via a cascade reaction. Chemical Science, 3. pp. 584-588. ISSN 1478-6524 doi: 10.1039/C1SC00592H

Rangam, G., Schmitz, K.-M., Cobb, A. and Petersen-Mahrt, S. (2012) AID enzymatic activity is inversely proportional to the size of cytosine C5 orbital cloud. PloS ONE, 7 (8). e43279. ISSN 1932-6203 doi: 10.1371/journal.pone.0043279

Shaikh, A. K., Cobb, A. J. A. and Varvounis, G. (2012) Mild and rapid method for the generation of ortho-(naphtho)-quinone methide intermediates. Organic Letters, 14 (2). pp. 584-587. ISSN 1523-7060 doi: 10.1021/ol203196n

2011

Benning, R. K., Osborn, H. M. I. and Turkson, A. (2011) Regioselective Beckmann rearrangements of furanoside and pyranoside-derived oximes. Tetrahedron: Asymmetry, 22 (1). pp. 109-116. ISSN 0957-4166 doi: 10.1016/j.tetasy.2010.11.031

Burland, P. A., Osborn, H. M. I. and Turkson, A. (2011) Synthesis and glycosidase inhibitory profiles of functionalised morpholines and oxazepanes. Bioorganic & Medicinal Chemistry, 19 (18). pp. 5679-5692. ISSN 0968-0896 doi: 10.1016/j.bmc.2011.07.019

Cobb, A. (2011) General aspects of organocatalytic cyclizations. In: Mahrwald, R. (ed.) Enantioselective Organocatalyzed Reactions II: Asymmetric C-C Bond Formation Processes. Springer, pp. 1-40. ISBN 9789048138661

Fante, C., Eldar-Boock, A., Satchi-Fainaro, R., Osborn, H. M. I. and Greco, F. (2011) Synthesis and biological evaluation of a polyglutamic acid-dopamine conjugate: a new antiangiogenic agent. Journal of Medicinal Chemistry, 54 (14). pp. 5255-5259. ISSN 0022-2623 doi: 10.1021/jm200382r

Fern, S. E., Heath, P. and Cobb, A. J. A. (2011) Aldol reaction of butane-2,3-diacetal protected methyl glycerate. Tetrahedron: Asymmetry, 22 (2). pp. 149-152. ISSN 0957-4166 doi: 10.1016/j.tetasy.2011.01.004

Sarsam, S. W., Nutt, D. R., Strohfeldt, K. and Watson, K. A. (2011) Titanocene anticancer complexes and their binding mode of action to human serum albumin: a computational study. Metallomics, 3 (2). pp. 152-161. ISSN 1756-5901 doi: 10.1039/c0mt00041h

2010

Bauer, J., Stiller, J., Marques-Lopez, E., Strohfeldt, K. A., Christmann, M. and Strohmann , C. (2010) Silyl-Modified Analogues of 2-Tritylpyrrolidine: Synthesis and Applications in Asymmetric Organocatalysis. Chemistry - A European Journal, 16 (42). pp. 12553-12558. ISSN 0947-6539 doi: 10.1002/chem.201002166

Burland, P. A., Coisson, D. and Osborn, H. M. I. (2010) Rapid synthesis of carbohydrate derivatives, including mimetics of c-linked disaccharides and c-Linked aza disaccharides, using the Hetero-Diels−Alder Reaction. Journal of Organic Chemistry, 75 (21). pp. 7210-7218. ISSN 0022-3263 doi: 10.1021/jo101219w

Carlescu, I., Osborn, H. M.I., Desbrieres, J., Scutaru, D. and Popa, M. (2010) Synthesis of poly(aspartimide)-based bio-glycoconjugates. Carbohydrate Research, 345 (1). pp. 33-40. ISSN 0008-6215 doi: 10.1016/j.carres.2009.08.034

Kolstoe, S. E., Mangione, P. P., Bellotti, V., Taylor, G. W., Tennent, G. A., Deroo, S., Morrison, A. J., Cobb, A. J. A., Coyne, A., McCammon, M. G., Warner, T. D., Mitchell, J., Gill, R., Smith, M. D., Ley, S. V., Robinson, S. P. and Pepys, M. B. (2010) Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Proceedings of the National Academy of Sciences of the United States of America, 107 (47). pp. 20483-20488. ISSN 0027-8424 doi: 10.1073/pnas.1008255107

Nodes, W. J., Shankland, K., Rajkumar, S. and Cobb, A. J. A. (2010) Asymmetric phase-transfer-catalyzed synthesis of five-membered cyclic gamma-Amino acid precursors. Synlett , 2010 (20). pp. 3011-3014. ISSN 1437-2096 doi: 10.1055/s-0030-1259050

Strohfeldt, K. and Grant, D. T. (2010) A model for self-directed problem-based learning for renal therapeutics. American Journal of Pharmaceutical Education , 74 (9). Article 173.

2009

Jawaid, S., Khan, T. H., Osborn, H. M. I. and Williams, N. O. A. (2009) Tyrosinase activated melanoma prodrugs. Anti-cancer agents in medicinal chemistry, 9 (7). pp. 717-727. ISSN 1871-5206

Nodes, W., Nutt, D. R., Chippindale, A. M. and Cobb, A. J. A. (2009) Enantioselective Intramolecular Michael Addition of Nitronates onto Conjugated Esters: Access to Cyclic γ-Amino Acids with up to Three Stereocenters. Journal of the American Chemical Society, 131 (44). pp. 16016-16017. ISSN 0002-7863 doi: 10.1021/ja9070915

Osborn, H. M. I. and Turkson, A. (2009) Synthesis and NMR spectroscopic analysis of 3-nitro-pyranoside, 3-nitro-septanoside and 4-nitro-septanoside derivatives by condensation of the anion of nitromethane with glycoside. Tetrahedron Asymmetry, 20 (18). pp. 2162-2166. ISSN 0957-4166 doi: 10.1016/j.tetasy.2009.08.004

Vessieres, A., Plamont, M.-A., Cabestaing, C., Claffey, J., Dieckmann, S., Hogan, M., Mueller-Bunz, H., Strohfeldt, K. A. and Tacke, M. (2009) Proliferative and anti-proliferative effects of titanium- and iron-based metallocene anti-cancer drugs. Journal of Organometallic Chemistry , 694 (6). pp. 874-879. ISSN 0022-328X doi: 10.1016/j.jorganchem.2008.11.071

2008

Baksh, M. F. and Kelly, P. (2008) Statistical methods for examining genetic influences of resistance to anti-epileptic drugs. Expert Review of Clinical Pharmacology, 1 (1). pp. 137-144. ISSN 1751-2433 doi: 10.1586/17512433.1.1.137

Bonjoch, J., Drew, M. G.B., Gonzalez, A., Greco, F., Jawaid, S., Osborn, H. M. I., Williams, N. A.O. and Yaqoob, P. (2008) Synthesis and evaluation of novel boron-containing complexes of potential use for the selective treatment of malignant melanoma. Journal of Medicinal Chemistry, 51 (20). pp. 6604-6608. ISSN 0022-2623 doi: 10.1021/jm8007745

Ellis, D., Norman, S. E. and Osborn, H. M. I. (2008) Synthesis of S-linked carbohydrate analogues via a Ferrier reaction. Tetrahedron, 64 (12). pp. 2832-2854. ISSN 0040-4020 doi: 10.1016/j.tet.2008.01.042

Strohfeldt, K. A. and Tacke, M. (2008) Bioorganometallic fulvene-derived titanocene anti-cancer drugs. Chemical Society Reviews, 37 (6). pp. 1174-1187. ISSN 0306-0012 doi: DOI:10.1039/b707310k

2007

Gaynor, J. W., Brazier, J. and Cosstick, R. (2007) Synthesis of 3 '-S-phosphorothiolate oligonucleotides for their potential use in RNA interference. Nucleosides Nucleotides & Nucleic Acids, 26 (6-7). pp. 709-712. ISSN 1525-7770 doi: 10.1080/15257770701490753

2005

Brazier, J. A., Shibata, T., Townsley, J., Taylor, B. F., Frary, E., Williams, N. H. and Williams, D. M. (2005) Amino-functionalized DNA: the properties of C5-amino-alkyl substituted 2′-deoxyuridines and their application in DNA triplex formation. Nucleic Acids Research, 33 (4). pp. 1362-1371. ISSN 1362-4962 doi: 10.1093/nar/gki254

This list was generated on Fri Apr 25 04:43:43 2014 BST.

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