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Number of items at this level: 357.

2014

Al-Mulla, H. M. N., Turrell, L., Smith, N. M., Payne, L., Baliji, S., Züst, R., Thiel, V., Baker, S. C., Siddell, S. G. and Neuman, B. W. (2014) Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions. mBio, 5 (2). e01107-13. ISSN 2150-7511 doi: 10.1128/mBio.01107-13

Alsohim, A. S., Taylor, T., Barrett, G. A., Gallie, J., Zhang, X.-X., Altamirano-Junqueira, A. E., Johnson, L., Rainey, P. B. and Jackson, R. (2014) The biosurfactant viscosin produced by Pseudomonas fluorescens SBW25 aids spreading motility and plant growth promotion. Environmental Microbiology. ISSN 1462-2920 doi: 10.1111/1462-2920.12469

Ambily, A., Kaiser, W.J., Pierro, C., Chamberlain, E.V., Li, Z., Jones, C.I., Kassouf, N., Gibbins, J. M. and Authi, K.S. (2014) The role of plasma membrane STIM1 and Ca(2+)entry in platelet aggregation. STIM1 binds to novel proteins in human platelets. Cellular Signalling, 26 (3). pp. 502-511. ISSN 0898-6568 doi: 10.1016/j.cellsig.2013.11.025

Angelini, M. M., Neuman, B. W. and Buchmeier, M. J. (2014) Untangling membrane rearrangement in the Nidovirales. DNA and Cell Biology, 33 (3). pp. 122-127. ISSN 1044-5498 doi: 10.1089/dna.2013.2304

Bhattacharya, B. S., Sweby, P. K., Minihane, A.-M., Jackson, K. G. and Tindall, M. J. (2014) A mathematical model of the sterol regulatory element binding protein 2 cholesterol biosynthesis pathway. Journal of Theoretical Biology, 349. pp. 150-162. ISSN 0022-5193 doi: 10.1016/j.jtbi.2014.01.013

Collins-Hooper, H., Sartori, R., Macharia, R., Visanuvimol, K., Foster, K., Matsakas, A., Flasskamp, H., Ray, S., Dash, P., Sandri, M. and Patel, K. (2014) Propeptide-mediated inhibition of myostatin increases muscle mass through inhibiting proteolytic pathways in aged mice. Journals of Gerontology Series A: Biological and Medical Sciences, 69 (9). pp. 1049-1059. ISSN 1079-5006 doi: 10.1093/gerona/glt170

Darbre, P. (2014) Environmental contaminants: Environmental estrogens - Hazard characterization. In: Encyclopaedia of Food Safety. Academic Press (Elsevier), Wathem MA, pp. 323-331. ISBN 9780123786128

Darbre, P. (2014) Hypersensitivity and growth adaptation of oestrogen-deprived MCF-7 human breast cancer cells. Anticancer Research, 34 (1). pp. 99-105. ISSN 0250-7005

Darbre, P. and Harvey, P. W. (2014) Parabens can enable hallmarks and characteristics of cancer in human breast epithelial cells: a review of the literature with reference to new exposure data and regulatory status. Journal of Applied Toxicology, 34 (9). pp. 925-938. ISSN 0260-437X doi: 10.1002/jat.3027

Dent, S. and Neuman, B. (2014) Purification of coronavirus virions for Cryo-EM and proteomic analysis. Methods in Molecular Biology. ISSN 1064-3745 (In Press)

Edgington, M. P. and Tindall, M. J. (2014) Fold-change detection in a whole-pathway model of Escherichia coli chemotaxis. Bulletin of Mathematical Biology, 76 (6). pp. 1376-1395. ISSN 0092-8240 doi: 10.1007/s11538-014-9965-3

Frost, G. S., Walton, G. E., Swann, J. R., Psichas, A., Costabile, A., Johnson, L. P., Sponheimer, M., Gibson, G. R. and Barraclough, T. G. (2014) Impacts of plant-based foods in ancestral hominin diets on the metabolism and function of gut microbiota in vitro. mBio, 5. e00853-14. ISSN 2150-7511 doi: 10.1128/mbio.00853-14

Gerry, A. B. and Leake, D. S. (2014) Effect of low extracellular pH on NF-κB activation in macrophages. Atherosclerosis, 233 (2). pp. 537-544. ISSN 0021-9150 doi: 10.1016/j.atherosclerosis.2014.01.014

Glister, C., Hatzirodos, N., Hummitzsch, K., Knight, P. G. and Rodgers, R. J. (2014) The global effect of follicle-stimulating hormone and tumour necrosis factor α on gene expression in cultured bovine ovarian granulosa cells. BMC Genomics, 15 (1). 72. ISSN 1471-2164 doi: 10.1186/1471-2164-15-72

Gritsun, D. J., Jones, I. M., Gould, E. A. and Gritsun, T. S. (2014) Molecular archaeology of Flaviviridae untranslated regions: duplicated RNA structures in the replication enhancer of flaviviruses and pestiviruses emerged via convergent evolution. PloS one, 9 (3). e92056. ISSN 1932-6203 doi: 10.1371/journal.pone.0092056

Holmes, A., Birse, L., Jackson, R. W. and Holden, N. J. (2014) An optimized method for the extraction of bacterial mRNA from plant roots infected with Escherichia coli O157:H7. Frontiers in Microbiology, 5. Article 286. ISSN 1664-302X doi: 10.3389/fmicb.2014.00286

Jones, C. I., Sage, T., Moraes, L. A., Vaiyapuri, S., Hussain, U., Tucker, K. L., Barrett, N. E. and Gibbins, J. M. (2014) Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein Ib via AKT/glycogen synthase kinase-3/dynamin and integrin αIIbβ3. Arteriosclerosis Thrombosis and Vascular Biology, 34 (9). pp. 1968-1976. ISSN 1079-5642 doi: 10.1161/ATVBAHA.114.304097

Jones, C. I., Tucker, K. L., Sasikumar, P., Sage, T., Kaiser, W. J., Moore, C., Emerson, M. and Gibbins, J. M. (2014) Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi. Journal of Thrombosis and Haemostasis, 12 (8). pp. 1342-1352. ISSN 1538-7933 doi: 10.1111/jth.12620

Khalil, N., Walton, G. E., Gibson, G. R., Tuohy, K. M. and Andrews, S. C. (2014) In vitro batch cultures of gut microbiota from healthy and ulcerative colitis (UC) subjects suggest that sulphate-reducing bacteria levels are raised in UC and by a protein-rich diet. International Journal of Food Science and Nutrition, 65 (1). pp. 79-88. ISSN 1465-3478 doi: 10.3109/09637486.2013.825700

Khanna, S., Dash, P. R. and Darbre, P. D. (2014) Exposure to parabens at the concentration of maximal proliferative response increases migratory and invasive activity of human breast cancer cells in vitro. Journal of Applied Toxicology. ISSN 0260-437X doi: 10.1002/jat.3003

Knight, P. and Glister, C. (2014) Theca cells and the regulation of ovarian androgen production. In: Juenge, J., Miyamoto, A., Price, C., Reynolds, L., Smith, M. and Webb, R. (eds.) Reproduction in Domestic Ruminants. Context, Ashby de la Zouche, pp. 295-310. ISBN 9781899043637

Lewin, M. R., Samuel, S. P., Wexler, D. S., Bickler, P., Vaiyapuri, S. and Mensh, B. D. (2014) Early treatment with intranasal neostigmine reduces mortality in a mouse model of Naja naja (Indian Cobra) envenomation. Journal of Tropical Medicine, 2014. 131835. ISSN 1687-9686 doi: 10.1155/2014/131835

Licciardello, G., Jackson, R.W., Bella, P., Strano, C.P., Catara, A.F., Arnold, D.L., Venturi, V., Silby, M.W. and Catara, V. (2014) Draft genome sequence of pseudomonas corrugata, a phytopathogenic bacterium with potential industrial applications. Journal of Biotechnology, 175. pp. 65-66. ISSN 0168-1656 doi: 10.1016/j.jbiotec.2014.02.003

Monteagudo, L. V., Ferrer, L. M., Catalan-Insa, E., Savva, D., McGuffin, L. and Tejedor, M. T. (2014) In silico identification and three-dimensional modelling of the missense mutation in ADAMTS2 in a sheep flock with dermatosparaxis. Veterinary Dermatology. ISSN 0959-4493 doi: 10.1111/vde.12178

Mulley, G., Jenkins, A. T. A. and Waterfield, N. R. (2014) Inactivation of the antibacterial and cytotoxic properties of silver ions by biologically relevant compounds. PLoS ONE, 9. e94409. ISSN 1932-6203 doi: 10.1371/journal.pone.0094409

Murray, E., Crowley, R., Truman, A., Clarke, S., Cottam, J., Jadhav, G., Steele, V., O'Shea, P., Lindholm, C., Cockayne, A., Chhabra, R., Chan, W. C. and Williams, P. (2014) Targeting Staphylococcus aureus quorum sensing with non-peptidic small molecule inhibitors. Journal of Medicinal Chemistry. ISSN 0022-2623 doi: 10.1021/jm500215s (In Press)

Neuman, B. W., Angelini, M. M. and Buchmeier, M. J. (2014) Does form meet function in the coronavirus replicative organelle? Trends in Microbiology. ISSN 0966-842X doi: 10.1016/j.tim.2014.06.003 (In Press)

Osman, A., Symeou, S., Trisse, V., Watson, K. A., Tzortzis, G. and Charalampopoulos, D. (2014) Synthesis of prebiotic galactooligosaccharides from lactose using bifidobacterial β-galactosidase (BbgIV) immobilised on DEAE-Cellulose, Q-Sepharose and amino-ethyl agarose. Biochemical Engineering Journal, 82. pp. 188-199. ISSN 1369-703X doi: 10.1016/j.bej.2013.11.020

Ren, J., Cone, A., Willmot, R. and Jones, I. M. (2014) Assembly of Recombinant Israeli Acute Paralysis virus capsids. PloS one, 9 (8). e105943.. ISSN 1932-6203 doi: 10.1371/journal.pone.0105943

Rhodes, G., Bosma, H., Studholme, D., Arnold, D. L., Jackson, R. W. and Pickup, R. W. (2014) The rulB gene of plasmid pWW0 is a hotspot for the site-specific insertion of integron-like elements found in the chromosomes of environmental Pseudomonas fluorescens group bacteria. Environmental Microbiology. ISSN 1462-2912 doi: 10.1111/1462-2920.12345

Roche, D. B., Buenavista, M. T. and McGuffin, L. J. (2014) Assessing the quality of modelled 3D protein structures using the ModFOLD server. In: Protein Structure Prediction. Methods in Molecular Biology, 1137. Springer, pp. 83-103. ISBN 9781493903658 doi: 10.1007/978-1-4939-0366-5_7

Saxon, E. B., Jackson, R. W., Bhumbra, S., Smith, T. and Sockett, R. E. (2014) Bdellovibrio bacteriovorus HD100 guards against Pseudomonas tolaasii brown-blotch lesions on the surface of post-harvest Agaricus bisporus supermarket mushrooms. BMC Microbiology, 14 (1). p. 163. ISSN 1471-2180 doi: 10.1186/1471-2180-14-163

Sarepta Pharmaceuticals, The Scripps Research Institute (2014) Oligonucleotide compound and method for treating nidovirus infections. USOO8759307B2 . doi: USOO8759307B2

Tindall, M. J. and Clerk, A. (2014) Modelling negative feedback networks for activating transcription factor 3 predicts a dominant role for miRNAs in immediate early gene regulation. PLoS Computational Biology, 10 (5). e1003597. ISSN 1553-734X doi: 10.1371/journal.pcbi.1003597

Tucci, V., Kleefstra, T., Hardy, A., Heise, I., Maggi, S., Willemsen, M. H., Hilton, H., Esapa, C., Simon, M., Buenavista, M.-T., McGuffin, L., Vizor, L., Dodero, L., Tsaftaris, S., Romero, R., Nillesen, W. N., Vissers, L. E.L.M., Kempers, M. J., Vulto-van Silfhout, A. T., Iqbal, Z., Orlando, M., Maccione, A., Lassi, G., Farisello, P., Constestabile, A., Tinarelli, F., Nieus, T., Raimondi, A., Greco, B., Cantatore, D., Gasparini, L., Berdondini, L., Bifone, A., Gozzi, A., Wells, S. and Nolan, P. M. (2014) Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features. The Journal of Clinical Investigation. ISSN 0021-9738 doi: 10.1172/JCI70372 (In Press)

2013

Amirak, E., Fuller, S. J., Sugden, P. H. and Clerk, A. (2013) p90 ribosomal S6 kinases play a significant role in early gene regulation in the cardiomyocyte response to Gq protein-coupled receptor stimuli, endothelin-1 and α1-adrenergic receptor agonists. Biochemical Journal, 450. pp. 351-363. ISSN 0264-6021 doi: 10.1042/BJ20121371 (In Press)

Anand-Ivell, R., Tremellen, K., Dai, Y., Heng, K., Yoshida, M., Knight, P. G., Hale, G. E. and Ivell, R. (2013) Circulating insulin-like factor 3 (INSL3) in healthy and infertile women. Human reproduction. ISSN 1460-2350 doi: 10.1093/humrep/det349

Angelini, M. M., Akhlaghpour, M., Neuman, B. W. and Buchmeier, M. J. (2013) Severe acute respiratory syndrome coronavirus nonstructural proteins 3, 4, and 6 induce double-membrane vesicles. mBio, 4 (4). e00524-13. ISSN 2150-7511 doi: 10.1128/mBio.00524-13

Antaloae, A. V., Montigny, C., le Maire, M., Watson, K. A. and Sorensen, T. L.-M. (2013) Optimisation of recombinant production of active human cardiac SERCA2a ATPase. PLoS ONE, 8 (8). e71842. ISSN 1932-6203 doi: 10.1371/journal.pone.0071842

Aravindan, L., Bicknell, K.A., Brooks, G., Khutoryanskiy, V.V. and Williams, A.C. (2013) A comparison of thiolated and disulfide‐crosslinked polyethylenimine for nonviral gene delivery. Macromolecular Bioscience, 13 (9). pp. 1163-1173. ISSN 1616-5187 doi: 10.1002/mabi.201300103

Atanu, F. O., Oviedo-Orta, E. and Watson, K. A. (2013) A novel transport mechanism for MOMP in Chlamydophila pneumoniae and its putative role in immune-therapy. PLoS ONE, 8 (4). e61139. ISSN 1932-6203 doi: 10.1371/journal.pone.0061139

Barrett, O. P. T., Yndestad, A., Marshall, A. K., Sugden, P. H. and Clerk, A. (2013) The early transcriptomic response to interleukin 1β and interleukin 33 in rat neonatal cardiomyocytes. Cytokine, 61 (2). pp. 340-344. ISSN 1096-0023 doi: 10.1016/j.cyto.2012.11.004

Charles, A. K. and Darbre, P. D. (2013) Combinations of parabens at concentrations measured in human breast tissue can increase proliferation of MCF-7 human breast cancer cells. Journal of Applied Toxicology. ISSN 0260-437X doi: 10.1002/jat.2850

Darbre, P. D. and Fernandez , M. F. (2013) Environmental oestrogens and breast cancer: long-term low-dose effects of mixtures of various chemical combinations. Journal of Epidemiology and Community Health, 67 (3). pp. 203-205. ISSN 1470-2738 doi: 10.1136/jech-2012-201362

Darbre, P. D., Bakir, A. and Iskakova, E. (2013) Effect of aluminium on migratory and invasive properties of MCF-7 human breast cancer cells in culture. Journal of Inorganic Biochemistry, 128. pp. 245-249. ISSN 0162-0134 doi: 10.1016/j.jinorgbio.2013.07.004

Darbre, P. D., Mannello, F. and Exley, C. (2013) Aluminium and breast cancer: sources of exposure, tissue measurements and mechanisms of toxicological actions on breast biology. Journal of Inorganic Biochemistry, 128. pp. 257-261. ISSN 0162-0134 doi: 10.1016/j.jinorgbio.2013.07.005

Dunwell, T., McGuffin, L., Dunwell, J. and Pfeifer, G. (2013) The mysterious presence of a 5-methylcytosine oxidase in the Drosophila genome: Possible explanations. Cell Cycle, 12 (21). 3357 -3365 . ISSN 1538-4101 doi: 10.4161/cc.26540

Gibbins, J. (2013) Platelets using proteins creatively. Blood, 122 (22). pp. 3553-3554. ISSN 0006-4971 doi: 10.1182/blood-2013-09-527663

Glister, C., Satchell, L., Bathgate, R. J., Wade, J. D., Dai, Y., Ivell, R., Anand-Ivell, R., Rodgers, R. J. and Knight, P. G. (2013) A functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production. Proceedings of the National Academy of Sciences of the United States of America, 110 (15). E1426-E1435. ISSN 0027-8424 doi: 10.1073/pnas.1222216110

Hooper, C. L., Paudyal, A., Dash, P. and Boateng, S. (2013) Modulation of stretch-induced myocyte remodeling and gene expression by nitric oxide: a novel role for lipoma preferred partner in myofibrillogenesis. American Journal of Physiology - Heart and Circulatory Physiology, 304 (10). H1302-H1313. ISSN 1522-1539 doi: 10.1152/ajpheart.00004.2013

House, E., Polwart, A., Darbre, P. D., Barr, L., Metaxas, G. and Exley, C. (2013) The aluminium content of breast tissue taken from women with breast cancer. Journal of Trace Elements in Medicine and Biology, 27. pp. 257-266. doi: 10.1016/j.jtemb.2013.05.002

Iourin, O., Harlos, K., El Omari, K., Lu, W., Kadlec, J., Iqbal, M., Meier, C., Palmer, A., Jones, I., Thomas, C., Brownlie, J., Grimes, J. M. and Stuart, D. I. (2013) Expression, purification and crystallization of the ectodomain of the envelope glycoprotein E2 from Bovine viral diarrhoea virus. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 69 (1). pp. 35-38. ISSN 1744-3091 doi: 10.1107/S1744309112049184

Jeanplong, F., Falconer, S. J., Oldham, J. M., Thomas, M., Gray, T. S., Hennebry, A., Matthews, K. G., Kemp, F., Patel, K., Berry, C., Nicholas, G. and McMahon, C. D. (2013) Discovery of a mammalian splice variant of myostatin that stimulates myogenesis. PLoS ONE, 8 (12). e81713. ISSN 1932-6203 doi: 10.1371/journal.pone.0081713

Kim, K., Hahm, E., Li, J., Holbrook, L.-M., Sasikumar, P., Stanley, R. G., Ushio-Fukai, M., Gibbins, J. M. and Cho, J. (2013) Platelet protein disulfide isomerase is required for thrombus formation but not essential for hemostasis in mice. Blood, 122 (6). pp. 1052-1061. ISSN 0006-4971 doi: 10.1182/blood-2013-03-492504

Kojadinovic, M., Armitage, J. P., Tindall, M. J. and Wadhams, G. H. (2013) Response kinetics in the complex chemotaxis signalling pathway of Rhodobacter sphaeroides. Journal of the Royal Society Interface, 10 (81). 20121001. ISSN 1742-5662 doi: 10.1098/rsif.2012.1001

Lee, T.E., Baines, M. J., Langdon, S. and Tindall, M. J. (2013) A moving mesh approach for modelling avascular tumour growth. Applied Numerical Mathematics, 72. pp. 99-114. ISSN 01689274 doi: 10.1016/j.apnum.2013.06.001

McGuffin, L. J., Buenavista, M. T. and Roche, D. B. (2013) The ModFOLD4 server for the quality assessment of 3D protein models. Nucleic Acids Research. ISSN 1362-4962 doi: 10.1093/nar/gkt294

McMahon, G. S., Jones, C. I., Hayes, P. D., Naylor, A. R. and Goodall, A. H. (2013) Transient heparin-induced platelet activation linked to generation of platelet 12-lipoxygenase: findings from a randomised controlled trial. Thrombosis and haemostasis, 109 (6). pp. 977-1185. ISSN 0340-6245 doi: 10.1160/TH12-11-0793

Moraes, L. A., Vaiyapuri, S., Sasikumar, P., Ali, M. S., Kriek, N. K., Sage, T. and Gibbins, J. M. (2013) Antithrombotic actions of statins involve PECAM-1 signalling. Blood, 122 (18). pp. 3188-3196. ISSN 0006-4971 doi: 10.1182/blood-2013-04-491845

Neuman, B. W. (2013) How the double spherules of infectious bronchitis virus impact our understanding of RNA virus replicative organelles. mBio, 4 (6). pp. 1-3. ISSN 2150-7511 doi: 10.1128/mBio.00987-13

Neuman, B. W., Chamberlain, P., Bowden, F. and Joseph, J. (2013) Atlas of coronavirus replicase structure. Virus research. ISSN 1872-7492 doi: 10.1016/j.virusres.2013.12.004

Neuman, B. W., Kiss, G., Al-Mulla, H. M. N., Dokland, T., Buchmeier, M. J., Weikl, T. and Schley, D. (2013) Direct observation of membrane insertion by enveloped virus matrix proteins by phosphate displacement. PLoS ONE, 8 (2). e57916. ISSN 1932-6203

Nykyri, J., Fang, X., Dorati, F., Bakr, R., Pasanen, M., Niemi, O., Palva, E. T., Jackson, R. W. and Pirhonen, M. (2013) Evidence that nematodes may vector the soft rot-causing enterobacterial phytopathogens. Plant Pathology. ISSN 0032-0862 doi: 10.1111/ppa.12159

Patel, A., Vasiljevic, S. and Jones, I. M. (2013) Unique structural properties associated with mouse prion Δ105-125 protein. PRION, 7 (3). pp. 235-243. ISSN 1933-690X doi: 10.4161/pri.24429

Porta, C., Kotecha, A., Burman, A., Jackson, T., Ren, J., Loureiro, S., Jones, I. M., Fry, E. E., Stuart, D. I. and Charleston, B. (2013) Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen. PLoS Pathogens, 9 (3). e1003255. ISSN 1553-7374 doi: 10.1371/journal.ppat.1003255

Porta, C., Xu, X., Loureiro, S., Paramasivam, S., Ren, J., Al-Khalil, T., Burman, A., Jackson , T., Blesham, G. J., Curry, S., Lomonossoff, G. P., Parida, S., Paton, D., Li, Y., Wilsden , G., Ferris, N., Owens, R., Kotecha, A., Fry , E., Stuart, D. I., Charleston, B. and Jones, I. M. (2013) Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity. Journal of Virological Methods, 187 (2). pp. 406-412. ISSN 0166-0934 doi: 10.1016/j.jviromet.2012.11.011

Pu, Q., Abduelmula, A., Masyuk, M., Theiss, C., Schwandulla, D., Hans, M., Patel, K., Brand-Saberi, B. and Huang, R. (2013) The dermomyotome ventrolateral lip is essential for the hypaxial myotome formation. BMC Developmental Biology, 13 (1). 37. ISSN 1471-213X doi: 10.1186/1471-213X-13-37

Roche, D. B., Buenavista, M. T. and McGuffin, L. J. (2013) The FunFOLD2 server for the prediction of protein-ligand interactions. Nucleic Acids Research. ISSN 1362-4962 doi: 10.1093/nar/gkt498

Satchell, L., Glister, C., Bleach, E. C., Glencross, R., Bicknell, A., Dai, Y., Anand-Ivell, R., Ivell, R. and Knight, P. G. (2013) Ovarian expression of insulin-like peptide 3 (INSL3) and its receptor (RXFP2) during development of bovine antral follicles and corpora lutea and measurement of circulating INSL3 levels during synchronized estrous cycles. Endocrinology, 154 (5). 1897-1906. ISSN 1945-7170 doi: 10.1210/en.2012-2232

Schley, D., Whittaker, R. J. and Neuman, B. W. (2013) Arenavirus budding resulting from viral-protein-associated cell membrane curvature. Journal of the Royal Society Interface, 10 (86). 20130403. ISSN 1742-5662 doi: 10.1098/rsif.2013.0403

Sugden, P. H., McGuffin, L. J. and Clerk, A. (2013) SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein–protein interactions. Biochemical Journal, 454 (1). pp. 13-30. ISSN 0264-6021 doi: 10.1042/BJ20130219

Taylor, T. B., Johnson, L. J., Jackson, R. W., Brockhurst, M. A. and Dash, P. R. (2013) First steps in experimental cancer evolution. Evolutionary Applications. ISSN 1752-4571 doi: 10.1111/eva.12041

Vaiyapuri, S., Ali, M. S., Moraes, L. A., Sage, T., Lewis, K. R., Jones, C. I. and Gibbins, J. M. (2013) Tangeretin regulates platelet function through inhibition of phosphoinositide 3-Kinase and cyclic nucleotide signaling. Arteriosclerosis Thrombosis and Vascular Biology, 33 (12). pp. 2740-2749. ISSN 1079-5642 doi: 10.1161/ATVBAHA.113.301988

Vaiyapuri, S., Moraes, L. A., Sage, T., Ali, M. S., Lewis, K. R., Mayhaut-Smith, M. P., Oviedo-Orta, E., Simon, A. M. and Gibbins, J. M. (2013) Connexin40 regulates platelet function. Nature Communications, 4. pp. 2564-2572. ISSN 2041-1723 doi: 10.1038/ncomms3564

Vaiyapuri, S., Vaiyapuri, R., Ashokan, R., Ramasamy, K., Nattamaisundar, K., Jeyaraj, A., Chandran, V., Gajjeraman, P., Baksh, M. F., Gibbins, J. M. and Hutchinson, E. G. (2013) Snakebite and its socio-economic impact on the rural population of Tamil Nadu, India. PLoS ONE, 8 (11). e80090. ISSN 1932-6203 doi: 10.1371/journal.pone.0080090

Waller, A. K., Sage, T., Kumar, C., Carr, T., Gibbins, J. M. and Clarke, S. R. (2013) Staphylococcus aureus lipoteichoic acid inhibits platelet activation and thrombus formation via the Paf receptor. Journal of Infectious Diseases, 208 (12). pp. 2046-2057. ISSN 1537-6613 doi: 10.1093/infdis/jit398

Wraith, K. S., Magwenzi, S., Aburima, A., Wen, Y., Leake, D. and Naseem, K. M. (2013) Oxidised low-density lipoproteins induce rapid platelet activation and shape change through tyrosine kinase and Rho kinase-signaling pathways. Blood, 122 (4). pp. 580-589. ISSN 0006-4971 doi: 10.1182/blood-2013-04-491688

Wright, B., Stanley, R. G., Kaiser, W. J. and Gibbins, J. M. (2013) The integration of proteomics and systems approaches to map regulatory mechanisms underpinning platelet function. Proteomics, Clinical Applications, 7 (1-2). pp. 144-154. ISSN 1862-8354 doi: 10.1002/prca.201200095

Xu, X., Chen, Y., Zhao, Y., Liu, X., Dong, B., Jones, I. M. and Chen, H. (2013) Baculovirus superinfection: a probable restriction factor on the surface display of proteins for library screening. PLoS ONE, 8 (1). e54631. ISSN 1932-6203 doi: 10.1371/journal.pone.0054631

2012

Barr, L., Metaxas, G., Harbach, C.A.J., Savoy, L.A. and Darbre, P. (2012) Measurement of paraben concentrations in human breast tissue at serial locations across the breast from axilla to sternum. Journal of Applied Toxicology. ISSN 1099-1263 doi: 10.1002/jat.1786 (In Press)

Bertling, A., Niemann, S., Hussain, M., Holbrook, L., Stanley, R. G., Brodde, M. F., Pohl, S., Schifferdecker, T., Roth, J., Jurk, K., Müller, A., Lahav, J., Peters, G., Heilmann, C., Gibbins, J. M. and Kehrel, B. E. (2012) Staphylococcal extracellular adherence protein induces platelet activation by stimulation of thiol isomerases. Arteriosclerosis Thrombosis and Vascular Biology, 32. pp. 1979-1990. ISSN 1079-5642 doi: 10.1161/ATVBAHA.112.246249

Buenavista, M. T., Roche, D. B. and McGuffin, L. J. (2012) Improvement of 3D protein models using multiple templates guided by single-template model quality assessment. Bioinformatics, 28 (14). pp. 1851-1857. ISSN 1460-2059 doi: 10.1093/bioinformatics/bts292

Collins-Hooper, H., Woolley, T. E., Dyson, L., Patel, A., Potter, P., Baker, R. E., Gaffney, E. A., Maini, P. K., Dash, P. and Patel, K. (2012) Age related changes in speed and mechanism of adult skeletal muscle stem cell migration. Stem Cells, 30 (6). pp. 1182-1195. ISSN 1066-5099 doi: 10.1002/stem.1088

Coxon, C. H., Lewis, A. M., Sadler, A. J., Vasudevan, S. R., Thomas, A., Dundas, K. A., Taylor, L., Campbell, R.D., Gibbins, J. M., Churchill, G. C. and Tucker, K. L. (2012) NAADP regulates human platelet function. Biochemical Journal, 441 (1). pp. 435-442. ISSN 0264-6021 doi: 10.1042/BJ20111175

Darbre, P. (2012) Molecular mechanisms of oestrogen action on growth of human breast cancer cells in culture. Hormone Molecular Biology and Clinical Investigation, 9 (1). pp. 65-85. ISSN 1868-1883 doi: 10.1515/hmbci-2011-0003

Di Yu, X., Dubnovitsky, A., Pudney, A. F., MacIntyre, S., Knight, S. D. and Zavialov, A. V. (2012) Allosteric mechanism controls traffic in the chaperone/usher pathway. Structure, 20 (11). pp. 1861-1871. ISSN 0969-2126 doi: 10.1016/j.str.2012.08.016

Elashry, M. I., Collins-Hooper, H., Vaiyapuri, S. and Patel, K. (2012) Characterisation of connective tissue from the hypertrophic skeletal muscle of myostatin null mice. Journal of Anatomy, 220 (6). pp. 603-611. ISSN 0021-8782 doi: 10.1111/j.1469-7580.2012.01503.x

Fuller, S. J., McGuffin, L. J., Marshall, A. K., Giraldo, A., Pikkarainen, S., Clerk, A. and Sugden, P. (2012) A novel, non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3). Biochemical Journal, 442 (3). pp. 595-610. ISSN 0264-6021 doi: 10.1042/BJ20112000

Gibbins, J. (2012) JAMming the signals. Blood, 119 (14). pp. 3197-3198. ISSN 1528-0020 doi: 10.1182/blood-2012-02-409060

Giraldo, A., Barrett, O., Tindall, M., Fuller, S., Amirak, E., Bhattacharya, B., Sugden, P. and Clerk, A. (2012) Feedback regulation by Atf3 in the endothelin-1-responsive transcriptome of cardiomyocytes: Egr1 is a principal Atf3 target. Biochemical Journal, 444 (2). pp. 343-355. ISSN 0264-6021 doi: 10.1042/BJ20120125

Glister, C., Satchell, L., Michael, A. E., Bicknell, A. B. and Knight, P. G. (2012) The anti-epileptic drug Valproic Acid (VPA) inhibits steroidogenesis in bovine theca and granulosa cells in vitro. PLoS ONE, 7 (11). e49553. ISSN 1932-6203 doi: 10.1371/journal.pone.0049553

Haapalainen, M., Mosorin, H., Dorati, F., Wu, R.-F., Roine, E., Taira, S., Nissinen, R., Mattinen, L., Jackson, R., Pirhonen, M. and Lin, N.-C. (2012) Hcp2, a secreted protein of the phytopathogen Pseudomonas syringae pv. tomato DC3000, is required for competitive fitness against bacteria and yeasts. Journal of Bacteriology, 194 (18). pp. 4810-4822. ISSN 1098-5530 doi: 10.1128/JB.00611-12

Holbrook, L.-M., Sasikumar, P., Stanley, R. G., Simmonds, A. D., Bicknell, A. B. and Gibbins, J. M. (2012) The platelet-surface thiol isomerase enzyme ERp57 modulates platelet function. Journal of Thrombosis and Haemostasis, 10 (2). pp. 278-288. ISSN 1538-7933 doi: 10.1111/j.1538-7836.2011.04593.x

Holtz, W., Wang, X., El-Gayar, M. and Knight, P.G. (2012) The effect of exogenous gonadotropins on ovarian function in goats actively immunized against inhibin. Theriogenology, 77 (12). pp. 253-259. ISSN 0093-691X doi: 10.1016/j.theriogenology.2011.07.037

Hooper, C. L., Dash, P. R. and Boateng, S. Y. (2012) Lipoma preferred partner is a mechanosensitive protein regulated by nitric oxide in the heart. FEBS Open Bio, 2. pp. 135-144. ISSN 2211-5463 doi: 10.1016/j.fob.2012.05.005 (In Press)

Jones, C. I., Moraes, L. A. and Gibbins, J. M. (2012) Regulation of platelet biology by platelet endothelial cell adhesion molecule-1. Platelets, 23 (5). pp. 331-335. ISSN 1369-1635 doi: 10.3109/09537104.2011.626091

Khanna, S. and Darbre, P. (2012) Parabens enable suspension growth of MCF-10A immortalized, non-transformed human breast epithelial cells. Journal of Applied Toxicology, 33 (5). pp. 378-382. ISSN 0260-437X doi: 10.1002/jat.2753

Knight, P. G., Satchell, L. and Glister, C. (2012) Intra-ovarian roles of activins and inhibins. Molecular and Cellular Endocrinology, 359 (1-2). pp. 53-65. ISSN 0303-7207 doi: 10.1016/j.mce.2011.04.024

Loureiro, S., Robinson, E., Chen, H., Phapugrangkul, P. , Colaco , C. and Jones, I. M. (2012) Vaccine glycoproteins tagged with the human Fc domain as second generation vaccine candidates. In: Baschieri, S. (ed.) Innovation in vaccinology. Springer, pp. 45-63. ISBN 9789400745421 doi: 10.1007/978-94-007-4543-8_3

Matsakas, A., Romanello, V., Sartori, R., Masiero, E., Macharia, R., Otto, A., Elashry, M., Sandri, M. and Patel, K. (2012) Food restriction reverses the hyper-muscular phenotype and force generation capacity deficit of the myostatin null mouse. International Journal of Sports Medicine, 33. ISSN 0172-4622 (In Press)

Murray, P. J., Edwards, C. M., Tindall, M. J. and Maini, P. K. (2012) Classifying general nonlinear force laws in cell-based models via the continuum limit. Physical Review E, 85 (2). 021921. ISSN 1550-2376 doi: 10.1103/PhysRevE.85.021921

Nicklas, S., Otto, A., Wu, X., Millar, P., Stelzer, S., Wen, Y., Kuang, S., Wrogemann, K., Patel, K., Ding, H. and Schwanborn, J. C. (2012) TRIM32 regulates skeletal muscle stem cell differentiation and is necessary for normal adult muscle regeneration. PLoS ONE, 7 (1). e30445. ISSN 1932-6203 doi: 10.1371/journal.pone.0030445

O'Flynn, N. M. J., Patel, A., Kadlec, J. and Jones, I. M. (2012) Improving promiscuous mammalian cell entry by the baculovirus AcMNPV. Bioscience Reports. BSR20120093. ISSN 0144-8463 doi: 10.1042/BSR20120093

Patel, A. and Dash, P. R. (2012) Formation of atypical podosomes in extravillous trophoblasts regulates extracellular matrix degradation. European Journal of Cell Biology, 91 (3). pp. 171-179. ISSN 0171-9335 doi: 10.1016/j.ejcb.2011.11.006

Pedersen, C., van Themaat, E. V., McGuffin, L., Abbott, J. C., Burgis, T. A., Barton, G., Bindschedler, L. V., Lu, X., Maekawa, T., Weßling, R., Cramer, R., Thordal-Christensen, H., Panstruga, R. and Spanu, P. D. (2012) Structure and evolution of barley powdery mildew effector candidates. BMC Genomics, 13 (1). p. 694. ISSN 1471-2164 doi: 10.1186/1471-2164-13-694

Roche, D. B., Buenavista, M. T. and McGuffin, L. (2012) Predicting protein structures and structural annotation of proteomes. In: Roberts, G. (ed.) Encylopedia of Biophysics. Springer-Verlag , Berlin Heidelberg . ISBN 9783642167119 (In Press)

Roche, D. B., Buenavista, M. T. and McGuffin, L. J. (2012) FunFOLDQA: a quality assessment tool for protein-ligand binding site residue predictions. PLoS ONE, 7 (5). e38219. ISSN 1932-6203 doi: 10.1371/journal.pone.0038219

Satchell, L. and Leake, D. (2012) Oxidation of low density lipoprotein by iron at lysosomal pH: implications for atherosclerosis. Biochemistry, 51 (18). pp. 3767-3775. ISSN 0006-2960 doi: 10.1021/bi2017975

Stefanini, L., Boulaftali, Y., Ouellette, T. D., Holinstat, M., Désiré, L., Leblond, B., Andre, P., Conley, P. and Bergmeier, W. (2012) Rap1-Rac1 circuits potentiate platelet activation. Arteriosclerosis Thrombosis and Vascular Biology, 32. pp. 434-441. ISSN 1524-4636 doi: 10.1161/ATVBAHA.111.239194

Tindall, M., Gaffney, E. A., Maini, P. K. and Armitage, J. P. (2012) Theoretical insights into bacterial chemotaxis. Wiley interdisciplinary reviews. Systems biology and medicine, 4 (3). pp. 247-259. ISSN 1939-005X doi: 10.1002/wsbm.1168

Tindall, M. J. (2012) Mathematics as a tool in the Life Sciences. In: HEA STEM Annual Conference - Biological Sciences Strand, 12-13 April, Imperial College, London.

Tindall, M. J., Dyson, L., Smallbone, K. and Maini, P. K. (2012) Modelling acidosis and the cell cycle in multicellular tumour spheroids. Journal of Theoretical Biology, 298. pp. 107-115. ISSN 0022-5193 doi: 10.1016/j.jtbi.2011.11.009

Vaiyapuri, S., Hutchinson, E. G., Ali, M. S., Dannoura, A., Stanley, R. G., Harrison, R. A., Bicknell, A. B. and Gibbins, J. M. (2012) Rhinocetin, a venom-derived integrin-specific antagonist inhibits collagen-induced platelet and endothelial cell functions. The Journal of Biological Chemistry, 287 (31). pp. 26235-26244. ISSN 1083-351X doi: 10.1074/jbc.M112.381483 (In Press)

Vaiyapuri, S., Jones, C. I., Sasikumar, P., Moraes, L. A., Munger, S. J., Wright, J. R., Ali, M. S., Sage, T., Kaiser, W. J., Tucker, K. L., Stain, C. J., Bye, A. P., Jones, S., Oviedo-Orta, E., Simon, A. M., Mahaut-Smith, M. P. and Gibbins, J. M. (2012) Gap junctions and connexin hemichannels underpin hemostasis and thrombosis. Circulation, 125 (20). pp. 2479-2491. ISSN 0009-7322 doi: 10.1161/CIRCULATIONAHA.112.101246

Vaiyapuri, S., Thiyagarajan, N., Hutchinson, G. and Gibbins, J. (2012) Sequence and phylogenetic analysis of viper venom serine proteases. Bioinformation, 8 (16). pp. 763-772. ISSN 0973-2063

Vandermeulen, G., Athanasopoulos, T., Trundley, A., Foster, K., Preat, V., Yanez-Munoz, R. J. and Dickson, G. (2012) Highly potent delivery method of gp160 envelope vaccine combining lentivirus-like particles and DNA electrotransfer. Journal of Controlled Release, 159 (3). pp. 376-383. ISSN 0168-3659 doi: 10.1016/j.jconrel.2012.01.035

Yu, X. D., Fooks, L. J., Moslehi-Mohebi, E., Tischenko, V. M., Askarieh, G., Knight, S. D., MacIntyre, S. and Zavialov, A. V. (2012) Large is fast, small is tight: determinants of speed and affinity in subunit capture by a periplasmic chaperone. Journal of molecular biology, 417 (4). pp. 294-308. ISSN 1089-8638 doi: 10.1016/j.jmb.2012.01.020

2011

Altonsy, M. O. and Andrews, S. C. (2011) Diallyl disulphide, a beneficial component of garlic oil, causes a redistribution of cell-cycle growth phases, induces apoptosis and enhances butyrate-induced apoptosis in colorectal adenocarcinoma cells (HT-29). Nutrition and Cancer, 63 (7). pp. 1104-1113. ISSN 1532-7914 doi: 10.1080/01635581.2011.601846

Amos, M. R., Sanchez-Contreras, M., Jackson, R. W., Munoz-Berbel, X., Ciche, T. A., Yang, G., Cooper, R. M. and Waterfield, N. R. (2011) Influence of the Photorhabdus luminescens phosphomannose isomerase gene, manA, on mannose utilization, exopolysaccharide structure, and biofilm formation. Applied and Environmental Microbiology, 77 (3). pp. 776-785. ISSN 0099-2240 doi: 10.1128/AEM.02326-10

Andrews, S. C. (2011) Making DNA without iron: induction of a manganese-dependent ribonucleotide reductase in response to iron starvation. Molecular Microbiolog, 80 (2). pp. 286-289. ISSN 1365-2958 doi: 10.1111/j.1365-2958.2011.07594.x

Arias, M. A., Loxley, A., Eatmon, C., Van Roey, G., Fairhurst, D., Mitchnick, M., Dash, P., Cole, T., Wegmann, F., Sattentau, Q. and Shattock, R. (2011) Carnauba wax nanoparticles enhance strong systemic and mucosal cellular and humoral immune responses to HIV-gp140 antigen. Vaccine, 29 (6). pp. 1258-1269. ISSN 0264-410X doi: 10.1016/j.vaccine.2010.11.084

Arnold, D. L., Lovell, H. C., Jackson, R. W. and Mansfield, J. W. (2011) Pseudomonas syringae pv. phaseolicola: from ‘has bean’ to supermodel. Molecular Plant Pathology, 12 (7). pp. 617-627. ISSN 1464-6722 doi: 10.1111/j.1364-3703.2010.00697.x

Artzrouni, M., Begg, C. B., Chabiniok, R., Clairambault, J., Foss, A., Hargrove, J., Lee, E. K., Siggers, J. S. and Tindall, M. (2011) The first international workshop on the role and impact of mathematics in medicine: a collective account. American Journal of Translational Research, 3 (5). pp. 492-497. ISSN 1943-8141

Bardaji, L., Añorga, M., Jackson, R. W., Martínez-Bilbao, A., Yanguas-Casás, N. and Murillo, J. (2011) Miniature transposable sequences are frequently mobilized in the bacterial plant pathogen Pseudomonas syringae pv. phaseolicola. PLoS ONE, 6 (10). e25773. ISSN 1932-6203 doi: 10.1371/journal.pone.0025773

Bindschedler, L. V., McGuffin, L. J., Burgis, T. A., Spanu, P. D. and Cramer, R. (2011) Proteogenomics and in silico structural and functional annotation of the barley powdery mildew Blumeria graminis f. sp. hordei. Methods, 54 (4). pp. 432-441. ISSN 1046-2023 doi: 10.1016/j.ymeth.2011.03.006

Cornelis, P., Wei, Q., Andrews, S. C. and Vinckx, T. (2011) Iron homeostasis and management of oxidative stress response in bacteria. Metallomics: integrated biometal science, 3 (6). pp. 540-549. ISSN 1756-591X doi: 10.1039/C1MT00022E

Darbre, P. (2011) Personal care products and breast cancer. In: Nriagu , J. (ed.) Encyclopedia of Environmental Health, Five-Volume Set. Elsevier, Burlington, pp. 395-406. ISBN 9780444522733

Darbre, P. D., Pugazhendhi, D. and Mannello, F. (2011) Aluminium and human breast diseases. Journal of Inorganic Biochemistry, 105 (11). pp. 1484-1488. ISSN 0162-0134 doi: 10.1016/j.jinorgbio.2011.07.017

Glister, C., Satchell, L. and Knight, P. G. (2011) Granulosal and thecal expression of bone morphogenetic protein- and activin-binding protein mRNA transcripts during bovine follicle development and factors modulating their expression in vitro. Reproduction, 142 (4). pp. 581-591. ISSN 1741-7899 doi: 10.1530/REP-11-0150

Godfrey, S. A. C., Lovell, H. C., Mansfield, J. W., Corry, D. S., Jackson, R. W. and Arnold, D. L. (2011) The stealth episome: suppression of gene expression on the excised genomic island PPHGI-1 from Pseudomonas syringae pv. phaseolicola. PLoS Pathogens, 7 (3). e1002010. ISSN 1553-7374 doi: 10.1371/journal.ppat.1002010

Hijazi, K., Wang, Y., Scala, C., Jeffs, S., Longstaff, C., Stieh, D., Haggarty, B., Vanham, G., Schols, D., Balzarini, J., Jones, I., Hoxie, J., Shattock, R. and Kelly, C. G. (2011) DC-SIGN increases the affinity of HIV-1 envelope glycoprotein interaction with CD4. PLoS ONE, 6 (12). e28307. ISSN 1932-6203 doi: 10.1371/journal.pone.0028307

Jackson, R. W., Johnson, L. J., Clarke, S. R. and Arnold, D. L. (2011) Bacterial pathogen evolution: breaking news. Trends in Genetics, 27 (1). pp. 32-40. ISSN 0168-9525 doi: 10.1016/j.tig.2010.10.001

Jackson, R. W., Vinatzer, B., Arnold, D. L., Dorus, S. and Murillo, J. (2011) The influence of the accessory genome on bacterial pathogen evolution. Mobile Genetic Elements, 1 (1). pp. 55-65. ISSN 2159-2543 doi: 10.4161/mge.1.1.16432

Jones, C. I., Barrett, T. E., Moraes, L. A., Gibbins, J. M. and Jackson, D. E. (2011) Endogenous inhibitory mechanisms and the regulation platelet function. In: Gibbins, J. and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes. vol. 3, Additional Protocols and Perspectives. Methods in Molecular Biology, vol. 788. Humana Press, pp. 341-366. ISBN 9781617793066

Kang, J. K., Malerba, A., Popplewell, L., Foster, K. and Dickson, G. (2011) Antisense-induced myostatin exon skipping leads to muscle hypertrophy in mice following Octa‑guanidine morpholino oligomer treatment. Molecular Therapy, 19 (1). pp. 159-164. ISSN 1525-0024 doi: 10.1038/mt.2010.212

Koo, T., Malerba, A., Athanasopoulos, T., Trollet, C., Boldrin, L., Ferry, A., Popplewell, L., Foster, H., Foster, K. and Dickson, G. (2011) Delivery of AAV2/9-microdystrophin genes incorporating helix 1 of the coiled-coil motif in the C-terminal domain of dystrophin improves muscle pathology and restores the level of α1-syntrophin and α-dystrobrevin in skeletal muscles of mdx mice. Level of α1-Syntrophin and α-Dystrobrevin in Skeletal Muscles of mdx Mice. Human Gene Therapy, 22 (11). pp. 1379-1388. ISSN 1557-7422 doi: 10.1089/hum.2011.020

Korf-Klingebiel, M., Kempf, T., Schlüter, K.-D., Willenbockel, C., Brod, T., Heineke, J., Schmidt, V. J., Jantzen, F., Brandes, R. P., Sugden, P. H., Drexler, H., Molkentin, J. D. and Wollert, K. C. (2011) Conditional transgenic expression of fibroblast growth factor 9 in the adult mouse heart reduces heart failure mortality after myocardial infarction. Circulation, 123 (5). pp. 504-14. ISSN 1524-4539 doi: 10.1161/CIRCULATIONAHA.110.989665

Loureiro, S., Ren, J., Phapugrangkul, P., Colaco, C. A., Bailey, C. R., Shelton, H., Molesti, E., Temperton, N. J., Barclay, W. S. and Jones, I. (2011) Adjuvant-free immunization with hemagglutinin-Fc fusion proteins as an approach to influenza vaccines. Journal of virology, 85 (6). pp. 3010-3014. ISSN 1098-5514 doi: 10.1128/JVI.01241-10

Mannello, F., Tonti, G. A., Medda, V., Simone , P. and Darbre, P. D. (2011) Analysis of aluminium content and iron homeostasis in nipple aspirate fluids from healthy women and breast cancer-affected patients. Journal of Applied Toxicology. ISSN 1099-1263 doi: 10.1002/jat.1641

McGuffin, L. J. and Roche, D. B. (2011) Automated tertiary structure prediction with accurate local model quality assessment using the IntFOLD-TS method. Proteins: Structure, Function, and Bioinformatics, 79 (S10). pp. 137-146. ISSN 1097-0134 doi: 10.1002/prot.23120

Moseley, F. L., Faircloth, M. E., Lockwood, W., Marber, M. S., Bicknell, K. A., Valasek, P. and Brooks, G. (2011) Limitations of the MRL mouse as a model for cardiac regeneration. Journal of Pharmacy and Pharmacology, 63 (5). pp. 648-656. ISSN 2042-7148 doi: 10.1111/j.2042-7158.2011.01261.x

Murray, P. J., Walter, A., Fletcher, A. G., Edwards, C. M., Tindall, M. J. and Maini , P. K. (2011) Comparing a discrete and continuum model of the intestinal crypt. Physical Biology, 8 (2). 026011. ISSN 1478-3975 doi: 10.1088/1478-3975/8/2/026011

Neuman, B. W., Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H. M. and Buchmeier, M. J. (2011) Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors. Antimicrobial Agents and Chemotherapy, 55 (10). pp. 4631-4638. ISSN 1098-6596 doi: 10.1128/AAC.00650-11

Neuman, B. W., Kiss, G., Kunding, A. H., Bhella, D., Baksh, M. F., Connelly, S., Droese, B., Klaus, J. P., Makino, S., Sawicki, S. G., Siddell, S. G., Stamou, D. G., Wilson, I. A., Kuhn, P. and Buchmeier, M. J. (2011) A structural analysis of M protein in coronavirus assembly and morphology. Journal of Structural Biology, 174 (1). pp. 11-22. ISSN 1047-8477 doi: 10.1016/j.jsb.2010.11.021

Otto, A., Collins-Hooper, H., Patel, A., Dash, P. R. and Patel, K. (2011) Adult skeletal muscle stem cell migration is mediated by a blebbing/amoeboid mechanism. Rejuvenation Research, 14 (3). pp. 249-260. ISSN 1549-1684 doi: 10.1089/rej.2010.1151

Ray, S. and Darbre, P. (2011) Crosstalk with insulin and dependence on PI3K/Akt/mTOR rather than MAPK pathways in upregulation of basal growth following long-term oestrogen deprivation in three human breast cancer cell lines. Hormone Molecular Biology and Clinical Investigation, 5 (2). pp. 53-65. ISSN 1868-1883 doi: 10.1515/HMBCI.2010.072

Ray, S., Fry, M. J. and Darbre, P. D. (2011) Enhanced sensitivity to rapamycin following long-term oestrogen deprivation in MCF-7, T-47-D and ZR-75-1 human breast cancer cells. Journal of Endocrinology, 208. pp. 21-29. ISSN 0022-0795 doi: 10.1677/JOE-10-0137

Roche, D. B., Buenavista, M. T., Tetchner, S. J. and McGuffin, L. J. (2011) The IntFOLD server: an integrated web resource for protein fold recognition, 3D model quality assessment, intrinsic disorder prediction, domain prediction and ligand binding site prediction. Nucleic Acids Research, 39 (Web Server). W171-W176. ISSN 1362-4962 doi: 10.1093/nar/gkr184

Roche, D. B., Tetchner, S. J. and McGuffin, L. J. (2011) FunFOLD: an improved automated method for the prediction of ligand binding residues using 3D models of proteins. BMC Bioinformatics, 12 (1). p. 160. ISSN 1471-2105 doi: 10.1186/1471-2105-12-160

Sarsam, S. W., Nutt, D. R., Strohfeldt, K. and Watson, K. A. (2011) Titanocene anticancer complexes and their binding mode of action to human serum albumin: a computational study. Metallomics, 3 (2). pp. 152-161. ISSN 1756-5901 doi: 10.1039/c0mt00041h

Seeds, R. E., Mukhopadhyay, S., Jones, I., Gordon, S. and Miller, J. L. (2011) The role of myeloid receptors on murine plasmacytoid dendritic cells in induction of type I interferon. International immunopharmacology, 11 (7). pp. 794-801. ISSN 1878-1705 doi: 10.1016/j.intimp.2011.01.013

Shelton, H., Ayora-Talavera, G., Ren, J., Loureiro, S., Pickles, R. J., Barclay, W. S. and Jones, I. M. (2011) Receptor binding profiles of avian influenza virus hemagglutinin subtypes on human cells as a predictor of pandemic potential. Journal of Virology, 85 (4). pp. 1875-1880. ISSN 0022-538X doi: 10.1128/JVI.01822-10

Silby, M. W., Winstanley, C., Godfrey, S. A.C., Levy, S. B. and Jackson, R. W. (2011) Pseudomonas genomes: diverse and adaptable. FEMS Microbiology Reviews, 35 (4). pp. 652-680. ISSN 1574-6976 doi: 10.1111/j.1574-6976.2011.00269.x

Spyridon, M., Moraes, L. A., Jones, C. I., Sage, T., Sasikumar, P., Bucci, G. and Gibbins, J. M. (2011) LXR as a novel antithrombotic target. Blood, 117 (21). pp. 5751-5761. ISSN 1528-0020 doi: 10.1182/blood-2010-09-306142

Stanley, R., Tucker, K., Barrett, T. and Gibbins, J. (2011) Platelets and their role in thrombotic and cardiovascular disease: the impact of proteomic analysis. In: Garcia, A. and Senis, Y. (eds.) Platelet Proteomics: Principles, Analysis and Applications. Mass Spectrometry . Wiley, pp. 3-26. ISBN 9780470463376

Stolla, M., Stefanini, L., Roden, R. C., Chavez, M., Hirsch, J., Greene, T., Ouellette, T. D., Maloney, S. F., Diamond, S. L., Poncz, M., Woulfe, D. S. and Bergmeier, W. (2011) The kinetics of αIIbβ3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy. Blood, 117 (3). pp. 1005-1013. ISSN 1528-0020 doi: 10.1182/blood-2010-07-297713

Sugden, P., Markou, T., Fuller, S. J., Tham, E. L., Molkentin, J., Paterson, H. and Clerk, A. (2011) Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active. Cellular Signalling, 23 (2). pp. 468-477. ISSN 0898-6568 doi: 10.1016/j.cellsig.2010.10.024

Tucker, K. L., Sage, T. and Gibbins, J. M. (2011) Clot retraction. In: Gibbins, J. M. and Mahaut-Smith, M. P. (eds.) Platelets and Megakaryocytes. vol. 3, Additional Protocols and Perspectives. Methods in Molecular Biology, vol. 788. Humana Press, pp. 101-108. ISBN 9781617793066

Tuplin, A., Evans, D. J., Buckley, A., Jones, I. M., Gould, E. A. and Gritsun, T. S. (2011) Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus. Nucleic Acids Research, 39 (16). pp. 7034-7048. ISSN 1362-4962 doi: 10.1093/nar/gkr237

Vaiyapuri, S., Wagstaff, S. C., Harrison, R. A., Gibbins, J. M. and Hutchinson, G. (2011) Evolutionary analysis of novel serine proteases in the venom gland transcriptome of Bitis gabonica rhinoceros. PLoS ONE, 6 (6). e21532. ISSN 1932-6203 doi: 10.1371/journal.pone.0021532

Valasek, P., Theis, S., DeLaurier, A., Hinits, Y., Luke, G. N., Otto, A. M., Minchin, J., He, L., Christ, B., Brooks, G., Sang, H., Evans, D. J., Logan, M., Huang, R. and Patel, K. (2011) Cellular and molecular investigations into the development of the pectoral girdle. Developmental Biology, 357 (1). pp. 108-116. ISSN 0012-1606 doi: 10.1016/j.ydbio.2011.06.031

Wright, B., Stanley, R. G., Kaiser, W. J., Mills, D. J. and Gibbins, J. M. (2011) Analysis of protein networks in resting and collagen receptor (GPVI)-stimulated platelet sub-proteomes. Proteomics, 11 (23). pp. 4588-4592. ISSN 1615-9853 doi: 10.1002/pmic.201100410

Yasmin, S., Andrews, S. C., Moore, G. R. and Le Brun, N. E. (2011) A new role for heme, facilitating release of iron from the bacterioferritin iron biomineral. The Journal of Biological Chemistry, 286 (5). pp. 3473-3483. ISSN 1083-351X doi: 10.1074/jbc.M110.175034

Zhou, Y., Adolfs, Y., Pijnappel, W. W. M. P., Fuller, S. J., Van der Schors, R. C., Li, K. W., Sugden, P. H., Smit, A. B., Hergovich, A. and Pasterkamp, R. J. (2011) MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis. Molecular and cellular biology, 31 (17). pp. 3603-3615. ISSN 1098-5549 doi: 10.1128/MCB.01389-10

Zust, R., Cervantes-Barragan, L., Habjan, M., Maier, R., Neuman, B. W., Ziebuhr, J., Szretter, K. J., Baker, S. C., Barchet, W., Diamond, M. S., Siddell, S. G., Ludewig, B. and Thiel, V. (2011) Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5. Nature Immunology, 12. pp. 137-143. ISSN 1529-2916 doi: 10.1038/ni.1979

van Doremalen, N., Shelton, H., Roberts, K. L., Jones, I., Pickles, R. J., Thompso, C. I. and Barclay, W. S. (2011) A single amino acid in the HA of pH1N1 2009 influenza virus affects cell tropism in human airway epithelium, but not transmission in ferrets. PLoS ONE, 6 (10). e25755. ISSN 1932-6203 doi: 10.1371/journal.pone.0025755

2010

Altonsy, M. O., Andrews, S. C. and Tuohy, K. M. (2010) Differential induction of apoptosis in human colonic carcinoma cells (Caco-2) by Atopobium, and commensal, probiotic and enteropathogenic bacteria: mediation by the mitochondrial pathway. International Journal of Food Microbiology, 137 (2-3). pp. 190-203. ISSN 0168-1605 doi: 10.1016/j.ijfoodmicro.2009.11.015

Andrews, S. C. (2010) The Ferritin-like superfamily: evolution of the biological iron storeman from a rubrerythrin-like ancestor. Biochimica Et Biophysica Acta-General Subjects, 1800 (8). pp. 691-705. ISSN 0304-4165 doi: 10.1016/j.bbagen.2010.05.010

Bommer, U.-A., Heng, C., Perrin, A., Dash, P., Lobov, S., Elia, A. and Clemens, M. J. (2010) Roles of the translationally controlled tumour protein (TCTP) and the double-stranded RNA-dependent protein kinase, PKR, in cellular stress responses. Oncogene, 29. pp. 763-773. ISSN 0950-9232 doi: 10.1038/onc.2009.380

Clarke, S. R. (2010) Phenol-soluble modulins of Staphylococcus aureus lure neutrophils into battle. Cell Host and Microbe, 7 (6). pp. 423-424. ISSN 1931-3128 doi: 10.1016/j.chom.2010.05.015

Cornelis, P. and Andrews, S. C., eds. (2010) Iron Uptake and Homeostasis in Microorganisms. Caister Academic Press, Norfolk, UK, pp302. ISBN 9781904455653

Darbre, P. (2010) Exposure to environmental oestrogenic chemicals and breast cancer. Current Medical Literature - Breast Cancer, 22 (4). pp. 113-122. ISSN 0956-6511 [print] 1759-8060 [online]

Darbre, P. D. and Charles, A. K. (2010) Environmental oestrogens and breast cancer: evidence for combined involvement of dietary, household and cosmetic xenoestrogens. Anticancer Research, 30 (3). pp. 815-827. ISSN 0250-7005

Dubnovitsky, A. P., Duck, Z., Kersley , J. E., Hard, J. E., MacIntyre, S. and Knight, S. D. (2010) Conserved hydrophobic clusters on the surface of the Caf1A usher C-terminal domain are important for F1 antigen assembly. Journal of Molecular Biology, 403 (2). pp. 243-259. ISSN 0022-2836 doi: 10.1016/j.jmb.2010.08.034

Glen, A., Evans, C. A., Gan, C. S., Cross, S. S., Hamdy, F. C., Gibbins, J., Lippitt, J., Eaton, C. L., Noirel, J., Wright, P. C. and Rehman, I. (2010) Eight-plex iTRAQ analysis of variant metastatic human prostate cancer cells identifies candidate biomarkers of progression: an exploratory study. The Prostate, 70 (12). pp. 1313-1332. ISSN 1097-0045 doi: 10.1002/pros.21167

Glister, C., Satchell, L. and Knight, P. G. (2010) Changes in expression of bone morphogenetic proteins (BMPs), their receptors and inhibin co-receptor betaglycan during bovine antral follicle development: inhibin can antagonize the suppressive effect of BMPs on thecal androgen production. Reproduction, 140 (5). pp. 699-712. ISSN 1470-1626 doi: 10.1530/REP-10-0216

Godfrey, S.A.C., Mansfield, J.W., Corry, D.S., Lovell, H.C., Jackson, R.W. and Arnold, D.L. (2010) Confocal imaging of pseudomonas syringae pv. phaseolicola colony development in bean reveals reduced multiplication of strains containing the genomic island PPHGI-1. Molecular Plant-Microbe Interactions, 23 (10). pp. 1294-1302. ISSN 0894-0282 doi: 10.1094 /MPMI -05-10-0114

Goodall, A. H., Burns, P., Salles, I., Macaulay, I. C., Jones, C. I., Ardissino, D., de Bono, B., Bray, S. L., Deckmyn, H., Dudbridge, F., Fitzgerald, D. J., Garner, S. F., Gusnanto, A., Koch, K., Langford, C., O'Connor, M. N., Rice, C. M., Stemple, D., Stephens, J., Trip, M. D., Zwaginga, J. J., Samani, N. J., Watkins, N. A., Maguire, P. B. and Ouwehand, W. H. (2010) Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function. Blood, 116 (22). pp. 4646-4656. ISSN 0006-4971 doi: 10.1182/blood-2010-04-280925

Green, S., Studholme, D.J., Laue, B.E., Dorati, F., Lovell, H., Arnold, D., Cottrell, J.E., Bridgett, S., Blaxter, M., Huitema, E., Thwaites, R., Sharpe, P.M., Jackson, R. and Kamoun, S. (2010) Comparative genome analysis provides insights into the evolution and adaptation of Pseudomonas syringae pv. aesculi on Aesculus hippocastanum. PLoS ONE, 5 (4). ISSN 1932-6203 doi: 10.1371/journal.pone.0010224

Holbrook, L. M., Watkins, N. A., Simmonds, A. D., Jones, C., Ouwehand, W. H. and Gibbins, J. M. (2010) Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation. British Journal of Haematology, 148 (4). pp. 627-637. ISSN 0007-1048 doi: 10.1111/j.1365-2141.2009.07994.x

Johnson, M. A., Chatterjee, A., Neuman, B. W. and Wuthrich, K. (2010) SARS coronavirus unique domain: three-domain molecular architecture in solution and RNA binding. Journal of Molecular Biology, 400 (4). pp. 724-742. ISSN 0022-2836 doi: 10.1016/j.jmb.2010.05.027

Knight, C.G., Zhang, X.X., Gunn, A., Brenner T., T., Jackson, R., Giddens, S.R., Prabhakar , S., Zitzmann, N. and Rainey, P.B. (2010) Testing temperature-induced proteomic changes in the plant-associated bacterium Pseudomonas fluorescens SBW25. Environmental Microbiology Reports, 2 (3). pp. 396-402. ISSN 1758-2229 doi: 10.1111/j.1758-2229.2009.00102.x

Kong, L., Sheppard, N. C., Stewart-Jones, G. B. E., Robson, C. L., Chen, H., Xu, X., Krashias, G., Bonomelli, C., Scanlan, C. N., Kwong, P. D., Jeffs, S. A., Jones, I. and Sattentau, Q. J. (2010) Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity. Journal of Molecular Biology, 403 (1). pp. 131-47. ISSN 0022-2836 doi: 10.1016/j.jmb.2010.08.033

Lovell, H. C., Jackson, R. W., Mansfield, J. W., Godfrey, S. A. C., Hancock, J. T., Desikan, R. and Arnold, D. L. (2010) In planta conditions induce genomic changes in Pseudomonas syringae pv. phaseolicola. Molecular Plant Pathology, 12 (2). pp. 167-176. ISSN 1464-6722 doi: 10.1111/j.1364-3703.2010.00658.x

Macharia, R., Valasek, P. and Patel, K. (2010) Neuromuscular junction morphology, fiber-type proportions, and satellite-cell proliferation rates are altered in MyoD(-/-) mice. Muscle & Nerve, 42 (1). pp. 38-52. ISSN 0148-639X doi: 10.1002/mus.21637

Malerba, A., Sharp, P. S., Graham, I. R., Arechavala-Gomeza, V., Foster, K., Muntoni, F., Wells, D. J. and Dickson, G. (2010) Chronic systemic therapy with low-dose morpholino oligomers ameliorates the pathology and normalizes locomotor behavior in mdx Mice. Molecular Therapy, 19 (2). pp. 345-354. ISSN 1525-0024 doi: 10.1038/mt.2010.261

Markou, T., Marshall, A. K., Cullingford, T., Tham, E. L., Sugden, P. and Clerk, A. (2010) Regulation of the cardiomyocyte transcriptome vs translatome by endothelin-1 and insulin: translational regulation of 5' terminal oligopyrimidine tract (TOP) mRNAs by insulin. BMC Genomics, 11. 343. ISSN 1471-2164 doi: 10.1186/1471-2164-11-343

Marshall, A. K., Barrett, O. P. T., Cullingford, T. E., Shanmugasundram, A., Sugden, P. and Clerk, A. (2010) ERK1/2 signaling dominates over RhoA signaling in regulating early changes in RNA expression induced by endothelin-1 in neonatal rat cardiomyocytes. PLoS ONE, 5 (4). e10027. ISSN 1932-6203 doi: 10.1371/journal.pone.0010027

McGuffin, L. J. (2010) Model quality prediction. In: Rangwala, H. and Karypis, G. (eds.) Introduction to protein structure prediction: methods and algorithms. Wiley, pp. 323-342. ISBN 9780470470596

McGuffin, L. J. and Roche, D. B. (2010) Rapid model quality assessment for protein structure predictions using the comparison of multiple models without structural alignments. Bioinformatics, 26 (2). pp. 182-188. ISSN 1460-2059 doi: 10.1093/bioinformatics/btp629

Moraes, L. A., Barrett, N. E., Jones, C., Holbrook, L. M., Spyridon , M., Sage, T., Newman, D. K. and Gibbins, J. M. (2010) Platelet endothelial cell adhesion molecule-1 regulates collagen-stimulated platelet function by modulating the association of phosphatidylinositol 3-kinase with Grb-2-associated binding protein-1 and linker for activation of T cells. Journal of Thrombosis and Haemostasis, 8 (11). pp. 2530-2541. ISSN 1538-7933 doi: 10.1111/j.1538-7836.2010.04025.x

Moraes, L. A., Spyridon, M., Kaiser, W. J., Jones, C., Sage, T., Atherton, R. E. and Gibbins, J. M. (2010) Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation. Journal of Thrombosis and Haemostasis, 8 (3). pp. 577-587. ISSN 1538-7933 doi: 10.1111/j.1538-7836.2009.03732.x

Nandal, A., Huggins, C. C. O., Woodhall, M. R., McHugh, J., Rodríguez-Quiñones, F., Quail, M. A., Guest, J. R. and Andrews, S. C. (2010) Induction of the ferritin gene (ftnA) of Escherichia coli by Fe2+–Fur is mediated by reversal of H-NS silencing and is RyhB independent. Molecular Microbiology, 75 (3). pp. 637-657. ISSN 0950-382X doi: 10.1111/j.1365-2958.2009.06977.x

Otto, A., Macharia, R., Matsakas, A., Valasek, P., Mankoo, B. S. and Patel, K. (2010) A hypoplastic model of skeletal muscle development displaying reduced foetal myoblast cell numbers, increased oxidative myofibres and improved specific tension capacity. Developmental Biology, 343 (1-2). pp. 51-62. ISSN 0012-1606 doi: 10.1016/j.ydbio.2010.04.014

Papandréou, M.-J., Barbouche, R., Guieu, R., Rivera, S., Fantini, J., Khrestchatisky, M., Jones, I. and Fenouillet, E. (2010) Mapping of domains on HIV envelope protein mediating association with calnexin and protein-disulfide isomerase. The Journal of Biological Chemistry, 285 (18). pp. 13788-13796. ISSN 1083-351X doi: 10.1074/jbc.M109.066670

Pickersgill, B. and Anderson, G. J. (2010) Travels with Charley - sunflowers and beyond: an appreciation of the life and work of Charles B. Heiser, Jr. (1920-2010). Economic Botany, 64 (4). pp. 281-286. ISSN 0013-0001 doi: 10.1007/s12231-010-9131-2

Pugazhendhi, D. and Darbre, P. D. (2010) Differential effects of overexpression of ERalpha and ERbeta in MCF10A immortalised, non-transformed human breast epithelail cells. Hormone Molecular Biology and Clinical Investigation, 1 (3). pp. 117-126. ISSN 1868-1883 doi: 10.1515/HMBCI.2010.013

Rajasekaran, M. B., Mitchell, S. A., Gibson, T. M., Hussain, R., Siligardi, G., Andrews, S. C. and Watson, K. A. (2010) Isolation and characterisation of EfeM, a periplasmic component of the putative EfeUOBM iron transporter of Pseudomonas syringae pv. syringae. Biochemical and Biophysical Research Communications, 398 (3). pp. 366-371. ISSN 0006-291X doi: 10.1016/j.bbrc.2010.06.072

Rajasekaran, M. B., Nilapwar, S., Andrews, S. C. and Watson, K. A. (2010) EfeO-cupredoxins: major new members of the cupredoxin superfamily with roles in bacterial iron transport. BioMetals, 23 (1). pp. 1-17. ISSN 0966-0844 doi: 10.1007/s10534-009-9262-z

Roche, D. B., Tetchner, S. J. and McGuffin, L. J. (2010) The binding site distance test score: a robust method for the assessment of predicted protein binding sites. Bioinformatics, 26 (22). pp. 2920-2921. ISSN 1460-2059 doi: 10.1093/bioinformatics/btq543

Shimeld, S. M., Boyle, M. J., Brunet, T., Luke, G. N. and Seaver, E. C. (2010) Clustered Fox genes in lophotrochozoans and the evolution of the bilaterian Fox gene cluster. Develomental Biology, 340 (2). pp. 234-248. ISSN 1095-564X doi: 10.1016/j.ydbio.2010.01.015

Shimeld, S. M., Degnan, B. and Luke, G. N. (2010) Evolutionary genomics of the Fox genes: origin of gene families and the ancestry of gene clusters. Genomics, 95 (5). pp. 256-260. ISSN 1089-8646 doi: 10.1016/j.ygeno.2009.08.002

Theis, S., Patel, K., Valasek, P., Otto, A., Pu, Q., Harel, I., Tzahor, E., Tajbakhsh, S., Christ, B. and Huang, R. (2010) The occipital lateral plate mesoderm is a novel source for vertebrate neck musculature. Development, 137 (17). pp. 2961-2971. ISSN 1477-9129

Theis, S., Patel, K., Valasek, P., Otto, A., Qui, P., Harel, I., Tzahor, E., Tajbakhsh, S., Christ, B. and Huang, R. (2010) The occipital lateral plate mesoderm - a novel source for vertebrate neck musculature. Development, 137 (17). pp. 2961-2971. ISSN 0950-1991 doi: 10.1242/dev.049726

Tindall, M. J., Porter, S. L., Maini, P. K. and Armitage, J. P. (2010) Modeling chemotaxis reveals the role of reversed phosphotransfer and a bi-functional kinase-phosphatase. PLoS Computational Biology, 6 (8). e1000896. ISSN 1553-734X doi: 10.1371/journal.pcbi.1000896

Trollet, C., Anvar, S.Y., Venema, A., Hargreaves, I.P., Foster, K., Vignaud, A., Ferry, A., Negroni, E., Hourde, C., Baraibar, M.A., t'Hoen, P.A.C., Davies, J.E., Rubinsztein, D.C., Heales, S.J., Mouly, V., van der Maarel, S.M., Butler-Browne, G., Raz, V. and Dickson, G. (2010) Molecular and phenotypic characterization of a mouse model of oculopharyngeal muscular dystrophy reveals severe muscular atrophy restricted to fast glycolytic fibres. Human Molecular Genetics, 19 (11). pp. 2191-2207. ISSN 1460-2083 doi: 10.1093/hmg/ddq098

Vaiyapuri, S., Harrison, R. A., Bicknell, A., Gibbins, J. M. and Hutchinson, E. G. (2010) Purification and functional characterisation of Rhinocerase, a novel serine protease from the venom of Bitis gabonica rhinoceros. PLoS ONE, 5 (3). e9687. ISSN 1932-6203 doi: 10.1371/journal.pone.0009687

Vaiyapuri, S., Wagstaff, S. C., Watson, K. A., Harrison, R. A., Gibbins, J. M. and Hutchinson, E. G. (2010) Purification and functional characterisation of rhiminopeptidase A, a novel aminopeptidase from the venom of Bitis gabonica rhinoceros. PLoS Neglected Tropical Diseases, 4 (8). e796. ISSN 1935-2735 doi: 10.1371/journal.pntd.0000796

Yndestad, A., Marshall, A. K., Hodgkinson, J., Tham, E. L., Sugden, P. and Clerk, A. (2010) Modulation of interleukin signalling and gene expression in cardiac myocytes by endothelin-1. International Journal of Biochemistry & Cell Biology, 42 (2). pp. 263-272. ISSN 1357-2725 doi: 10.1016/j.biocel.2009.10.021

Zhou, H. G., Standfuss, J., Watson, K. A. and Krasel, C. (2010) Structure of full-length arrestin2 in a dimeric crystal form. In: 51st Annual Meeting of the Deutsche-Gesellschaft-fur-Experimentelle-und-Klinische-Pharmakologie-und-Toxikologie, 23-25 Mar 2010, Mainz, Germany.

2009

Canobbio, I., Stefanini, L., Cipolla, L., Ciraolo, E., Gruppi, C., Balduini, C., Hirsch, E. and Torti, M. (2009) Genetic evidence for a predominant role of PI3Kβ catalytic activity in ITAM- and integrin-mediated signaling in platelets. Blood, 114 (10). pp. 2193-2196. ISSN 1528-0020 doi: 10.1182/blood-2009-03-208074

Clerk, A., Cullingford, T. E., Fuller, S., Giraldo, A. and Sugden, P. (2009) Endothelin-1 regulation of immediate early gene expression in cardiac myocytes: negative feedback regulation of interleukin 6 by Atf3 and Klf2. Advances in Enzyme Regulation, 49 (1). pp. 30-42. ISSN 0065-2571 doi: 10.1016/j.advenzreg.2008.12.007

Foster, K., Graham, I. R., Otto, A., Foster, H., Trollet, C., Yaworsky, P. J., Walsh, F. S., Bickham, D., Curtin, N. A., Kawar, S. L., Patel, K. and Dickson, G. (2009) Adeno-associated virus-8-Mediated intravenous transfer of myostatin propeptide leads to systemic functional improvements of slow but not fast muscle. Rejuvenation Research, 12 (2). pp. 85-93. ISSN 1549-1684 doi: 10.1089/rej.2008.0815

AVI Biopharma, The Scripps Research Institute (2009) Antisense antiviral compound and method for treating arenavirus infection. US7582615 B2. doi: US7582615 B2

Pikkarainen, S., Kennedy, R., Marshall, A. K., Tham, E. L., Lay , K., Kriz, T., Handa, B., Clerk, A. and Sugden, P. (2009) Regulation of expression of the rat orthologue of mouse double minute 2 (MDM2) by H2O2-induced oxidative stress in neonatal rat cardiac myocytes. The Journal of Biological Chemistry, 284 (40). pp. 27195-27210. ISSN 1083-351X doi: 10.1074/jbc.M109.037887

Serrano, P., Johnson, M. A., Chatterjee, A., Neuman, B. W., Joseph, J. S., Buchmeier, M. J., Kuhn, P. and Wuthrich, K. (2009) Nuclear magnetic resonance structure of the nucleic acid-binding domain of severe acute respiratory syndrome coronavirus nonstructural protein 3. Journal of Virology, 83 (24). pp. 12998-13008. ISSN 0022-538X doi: 10.1128/jvi.01253-09

Stefanini, L., Roden, R. C. and Bergmeier, W. (2009) CalDAG-GEFI is at the nexus of calcium-dependent platelet activation. Blood, 114 (12). pp. 2506-2514. ISSN 1528-0020 doi: 10.1182/blood-2009-04-218768

2008

Bamford, V. A., Armour, M., Mitchell, S. A., Cartron, M., Andrews, S. C. and Watson, K. A. (2008) Preliminary X-ray diffraction analysis of YqjH from Escherichia coli: a putative cytoplasmic ferri-siderophore reductase. Acta Crystallographica Section F-Structural Biology and Crystallization Communications, 64 (9). pp. 792-796. ISSN 1744-3091 doi: 10.1107/S174430910802352X

Bicknell, K. A. and Brooks, G. (2008) Reprogramming the cell cycle machinery to treat cardiovascular disease. Current Opinion in Pharmacology, 8 (2). pp. 193-201. ISSN 1471-4892 doi: 10.1016/j.coph.2007.12.015

Clarke, S. R. and Foster, S. J. (2008) IsdA protects Staphylococcus aureus against the bactericidal protease activity of apolactoferrin. Infection and Immunity, 76 (4). pp. 1518-1526. ISSN 0019-9567 doi: 10.1128/IAI.01530-07

Cullingford, T. E., Butler, M. J., Marshall, A. K., Tham, E. L., Sugden, P. H. and Clerk, A. (2008) Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: effects of endothelin-1, oxidative stress and cytokines. Biochimica Et Biophysica Acta-Molecular Cell Research, 1783 (6). pp. 1229-1236. ISSN 0167-4889 doi: 10.1016/j.bbamcr.2008.03.007

Cullingford, T. E., Markou, T., Fuller, S. J., Giraldo Ramirez, A., Pikkarainern, S., Zoumpoulidou, G., Alsafi, A., Ekere, C., Kemp, T. J., Dennis, J. L., Game, L., Sugden, P. and Clerk, A. (2008) Temporal regulation of expression of immediate early and second phase transcripts by endothelin-1 in cardiomyocytes. Genome Biology, 9 (2). R32. ISSN 1474-760X doi: 10.1186/gb-2008-9-2-r32

Foster, H., Sharp, P. S., Athanasopoulos, T., Trollet, C., Graham, I. R., Foster, K., Wells, D. J. and Dickson, G. (2008) Codon and mRNA sequence optimization of microdystrophin transgenes improves expression and physiological outcome in dystrophic mdx mice following AAV2/8 gene transfer. Molecular Therapy, 16 (11). pp. 1825-1832. ISSN 1525-0024 doi: 10.1038/mt.2008.186

Fuller, S. J., Pikkarainen, S., Tham, E. L., Cullingford, T. E., Molkentin, J. D., Cornils, H., Hergovitch, A., Hemmings, B. A., Clerk, A. and Sugden, P. H. (2008) Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors. Cellular Signalling, 20 (8). pp. 1564-1577. ISSN 0898-6568 doi: 10.1016/j.cellsig.2008.04.013

Garner, S. F., Jones, C. I., Stephens, J., Burns, P., Walton, J., Bernard, A., Angenent, W., Ouwehand, W. H. and Goodall, A. H. (2008) Apheresis donors and platelet function: inherent platelet responsiveness influences platelet quality. Transfusion, 48 (4). pp. 673-680. ISSN 0041-1132 doi: 10.1111/j.1537-2995.2007.01591.x

Gerry, A. B. and Leake, D. S. (2008) A moderate reduction in extracellular pH protects macrophages against apoptosis induced by oxidised low density lipoprotein. Journal of Lipid Research, 49 (4). pp. 782-789. ISSN 1539-7262 doi: 10.1194/jlr.M700349-JLR200

Jensen, R. O., Winzer, K., Clarke, S. R., Chan, W. C. and Williams, P. (2008) Differential recognition of Staphylococcus aureus quorum-sensing signals depends on both extracellular loops 1 and 2 of the transmembrane sensor AgrC. Journal of Molecular Biology, 381 (2). pp. 300-309. ISSN 0022-2836 doi: 10.1016/j.jmb.2008.06.018

Jones, C. I. , Payne, D. A., Hayes, P. D., Naylor, A. R., Bell, P. R. F., Thompson, M. M. and Goodall, A. H. (2008) The antithrombotic effect of dextran-40 in man is due to enhanced fibrinolysis in vivo. Journal of Vascular Research, 48 (3). pp. 715-722. ISSN 1018-1172 doi: 10.1016/j.jvs.2008.04.008

Markou, T., Cullingford, T. E., Giraldo Ramirez, A., Weiss, S. C., Alsafi, A., Fuller, S. J., Clerk, A. and Sugden, P. H. (2008) Glycogen synthase kinases 3α and 3β in cardiac myocytes: regulation and consequences of their inhibition. Cellular Signalling, 20 (1). pp. 206-218. ISSN 0898-6568 doi: 10.1016/j.cellsig.2007.10.004

Otto, A., Schmidt, C., Luke, G., Allen, S., Valasek, P., Muntoni, M., Lawrence-Watt, D. and Patel, K. (2008) Canonical Wnt signalling induces satellite-cell proliferation during adult skeletal muscle regeneration. Journal of Cell Science, 121 (17). pp. 2939-2950. ISSN 1477-9137 doi: 10.1242/jcs.026534

Prasad, S. K., Clerk, A., Cullingford, T. E., Chen, A. W. Y., Kemp, T. J., Cannell, T. M., Cowie, M. R. and Petrou, M. (2008) Gene expression profiling of human hibernating myocardium: Increased expression of B-type natriuretic peptide and proenkephalin in hypocontractile vs normally-contracting regions of the heart. European Journal of Heart Failure, 10 (12). pp. 1177-1180. ISSN 1388-9842 doi: 10.1016/j.ejheart.2008.08.008

Sinclair, H.R., Smejkal, C.W., Glister, C., Kemp, F., van den Heuvel, E., de Slegte, J., Gibson, G.R. and Rastall, R.A. (2008) Sialyloligosaccharides inhibit cholera toxin binding to the GM1 receptor. Carbohydrate Research, 343 (15). pp. 2589-2594. ISSN 0008-6215 doi: 10.1016/j.carres.2008.07.008

2007

Baksh, M. F., Balding, D. J., Vyse, T. J. and Whittaker, J. C. (2007) Family-based association analysis with ordered categorical phenotypes, covariates and interactions. Genetic Epidemiology, 31 (1). pp. 1-8. ISSN 0741-0395 doi: 10.1002/gepi.20183

George, V.T., Brooks, G. and Humphrey, T.C. (2007) Regulation of cell cycle and stress responses to hydrostatic pressure in fission yeast. Molecular Biology of the Cel, 18 (10). pp. 4168-4179. ISSN 1059-1524 doi: 10.1091/mbc.E06-12-1141

Harrison, S.M., Dove, B.K., Rothwell, L., Kaiser, P., Tarpey, I., Brooks, G. and Hiscox, J.A. (2007) Characterisation of cyclin D1 down-regulation in coronavirus infected cells. FEBS Letters, 581 (7). pp. 1275-1286. ISSN 0014-5793 doi: 10.1016/j.febslet.2007.02.039

Jones, C. I., Garner, S. F., Angenent, W., Bernard, A., Berzuini, C., Burns, P., Farndale, R. W., Hogwood, J., Rankin, A., Stephens, J. C., Tom, B. D., Walton, J., Dudbridge, F., Ouwehand, W. H. and Goodall, A. H. (2007) Mapping the platelet profile for functional genomic studies and demonstration of the effect size of the GP6 locus. Journal of Thrombosis and Haemostasis, 5 (8). pp. 1756-1765. ISSN 1538-7933 doi: 10.1111/j.1538-7836.2007.02632.x

Li, J.M., Fan, L.M., George, V.T. and Brooks, G. (2007) Nox2 regulates endothelial cell cycle arrest and apoptosis via p21 (cip1) and p53. Free Radical Biology and Medicine, 43 (6). pp. 976-986. ISSN 0891-5849 doi: 10.1016/j.freeradbiomed.2007.06.001

Moseley, F.L., Bicknell, K.A., Marber, M.S. and Brooks, G. (2007) The use of proteomics to identify novel therapeutic targets for the treatment of disease. Journal of Pharmacy and Pharmacology, 59 (5). pp. 609-628. ISSN 0022-3573 doi: 10.1211/jpp.59.5.0001

Palmblad, M., Mills, D. J., Bindschedler, L.V. and Cramer, R. (2007) Chromatographic alignment of LC-MS and LC-MS/MS datasets by genetic algorithm feature extraction. Journal of the American Society for Mass Spectrometry, 18 (10). pp. 1835-1843. ISSN 1044-0305 doi: 10.1016/j.jasms.2007.07.018

Payne, D. A., Jones, C. I., Hayes, P. D., Naylor, A. R. and Goodall, A. H. (2007) Therapeutic benefit of low-dose clopidogrel in patients undergoing carotid surgery is linked to variability in the platelet adenosine diphosphate response and patients' weight. Stroke, 38 (9). pp. 2464-2469. ISSN 0039-2499 doi: 10.1161/STROKEAHA.107.486787

Wen, Y. and Leake, D. S. (2007) Low density lipoprotein undergoes oxidation within lysosomes in cells. Circulation Research, 100. pp. 1337-1343. ISSN 0009-7330 doi: 10.1161/CIRCRESAHA.107.151704

Zhao, J. H., Luan, J.’a. , Baksh, M. F. and Tan, Q. (2007) Mining gene networks with application to GAW15 problem 1. BMC Proceedings, 1 (Supp 1). S52. ISSN 1753-6561

2006

Cartron, M. L., Maddocks, S., Gillingham, P., Craven, C. J. and Andrews, S. C. (2006) Feo-transport of ferrous iron into bacteria. BioMetals, 19 (2). pp. 143-57. ISSN 0966-0844 doi: 10.1007/s10534-006-0003-2

Morissette, M.R., Cook, S.A., Foo, S., McKoy, G., Ashida, N., Novikov, M., Scherrer-Crosbie, M., Li, L., Matsui, T., Brooks, G. and Rosenzweig, A. (2006) Myostatin regulates cardiomyocyte growth through modulation of Akt signaling. Circulation Research, 99 (1). pp. 15-24. ISSN 0009-7330 doi: 10.1161/01.RES.0000231290.45676.d4

Osborne, P.W., Luke, G., Holland, P.W. and Ferrier, D.E. (2006) Identification and characterisation of five novel miniature inverted-repeat transposable elements (MITEs) in amphioxus (Branchiostoma floridae). International Journal of Biological Sciences, 2 (2). pp. 54-60. ISSN 1449-2288

Toff, W. D., Jones, C. I., Ford, I., Pearse, R. J., Watson, H. G., Watt, S. J., Ross, J. A., Gradwell, D. P., Batchelor, A. J., Abrams, K. R., Meijers, J. C., Goodall, A. H. and Greaves, M. (2006) Effect of hypobaric hypoxia, simulating conditions during long-haul air travel, on coagulation, fibrinolysis, platelet function, and endothelial activation. Jama-Journal of the American Medical Association, 295 (19). pp. 2251-2261. ISSN 0098-7484 doi: 10.1001/jama.295.19.2251

2005

Bryson, K., McGuffin, L. J., Marsden, R. L., Ward, J. J., Sodhi, J. S. and Jones, D. T. (2005) Protein structure prediction servers at University College London. Nucleic Acids Research, 33 (S2). W36-W38. ISSN 1362-4962 doi: 10.1093/nar/gki410

Humphrey, T. and Brooks, G., eds. (2005) Cell cycle control: mechanisms and protocols. Methods in molecular biology, 296. Humana Press, New Jersey, pp402. ISBN 9781588291448

Jackson, R. W., Preston, G. M. and Rainey, P. B. (2005) Genetic characterization of pseudomonas fluorescens SBW25 rsp gene expression in the phytosphere and in vitro. Journal of Bacteriology, 187 (24). pp. 8477-8488. ISSN 1098-5530 doi: 10.1128/JB.187.24.8477-8488.2005

Joardar, V., Lindeberg, M., Jackson, R. W., Selengut, J., Dodson, R., Brinkac, L. M., Daugherty, S. C., DeBoy, R., Durkin, A. S., Giglio, M. G., Madupu, R., Nelson, W. C., Rosovitz, M. J., Sullivan, S., Crabtree, J., Creasy, T., Davidsen, T., Haft, D. H., Zafar, N., Zhou, L., Halpin, R., Holley, T., Khouri, H., Feldblyum, T., White, O., Fraser, C. M., Chatterjee, A. K., Cartinhour, S., Schneider, D. J., Mansfield, J., Collmer, A. and Buell, C. R. (2005) Whole-genome sequence analysis of pseudomonas syringae pv. phaseolicola 1448A reveals divergence among pathovars in genes involved in virulence and transposition. Journal of Bacteriology, 187 (18). pp. 6488-6498. ISSN 0021-9193 doi: 10.1128/JB.187.18.6488-6498.2005

Jones, D. T., Bryson, K., Coleman, A., McGuffin, L. J., Sadowski, M. I., Sodhi, J. S. and Ward, J. J. (2005) Prediction of novel and analogous folds using fragment assembly and fold recognition. Proteins: Structure, Function, and Bioinformatics, 61 (S7). pp. 143-151. ISSN 1097-0134 doi: 10.1002/prot.20731

Pettitt, C. S., McGuffin, L. J. and Jones, D. T. (2005) Improving sequence-based fold recognition by using 3D model quality assessment. Bioinformatics, 21 (17). pp. 3509-3515. ISSN 1460-2059 doi: 10.1093/bioinformatics/bti540

Pitman, A. R., Jackson, R. W., Mansfield, J. W., Kaitell, V., Thwaites, R. and Arnold, D. L. (2005) Exposure to host resistance mechanisms drives evolution of bacterial virulence in plants. Current Biology, 15 (24). pp. 2230-2235. ISSN 0960-9822 doi: 10.1016/j.cub.2005.10.074

Rivas, L. A., Mansfield, J., Tsiamis, G., Jackson, R. W. and Murillo, J. (2005) Changes in race-specific virulence in pseudomonas syringae pv. phaseolicola are Associated with a chimeric transposable element and rare deletion events in a plasmid-borne pathogenicity island. Applied and Environmental Microbiology, 71 (7). pp. 3778-3785. ISSN 0099-2240 doi: 10.1128/AEM.71.7.3778-3785.2005

Scortichini, M., Rossi, M. P., Loreti, S., Bosco, A., Fiori, M., Jackson, R. W., Stead, D. E., Aspin, A., Marchesi, U., Zini, M. and Janse, J. D. (2005) Pseudomonas syringae pv. coryli, the causal agent of bacterial twig dieback of Corylus avellana. Phytopathology, 95 (11). pp. 1316-1324. ISSN 0031-949X doi: 10.1094/PHYTO-95-1316

2004

Edwards, S., Tucker, K. and McCann, C. (2004) The contribution of verb retrieval to sentence construction: a clinical study. Brain and Language, 91 (1). pp. 78-79. ISSN 0093-934x doi: 10.1016/j.bandl.2004.06.042 (special abstract issue: Academy of Aphasia 2004 Program)

McGuffin, L. J., Street, S. A. , Bryson, K. , Sørensen, S.‐A. and Jones, D. T. (2004) The Genomic Threading Database: a comprehensive resource for structural annotations of the genomes from key organisms. Nucleic Acids Research, 32 (S1). D196-D199. ISSN 1362-4962 doi: 10.1093/nar/gkh043

McGuffin, L. J., Street, S., Sorensen, S.-A. and Jones, D. T. (2004) The Genomic Threading Database. Bioinformatics, 20 (1). pp. 131-132. ISSN 1460-2059 doi: 10.1093/bioinformatics/btg387

Sodhi, J. S., Bryson, K., McGuffin, L. J., Ward, J. J., Wernisch, L. and Jones, D. T. (2004) Predicting metal-binding site residues in low-resolution structural models. Journal of Molecular Biology, 342 (1). pp. 307-320. ISSN 0022-2836 doi: 10.1016/j.jmb.2004.07.019

Sodhi, J. S., McGuffin, L. J., Bryson, K., Ward, J. J., Wernisch, L. and Jones, D. T. (2004) Automatic prediction of functional site regions in low-resolution protein structures. In: Proceedings. 2004 IEEE Computational Systems Bioinformatics Conference, 2004. CSB 2004. IEEE, pp. 702-703. doi: 10.1109/CSB.2004.1332551

Ward, J. J., McGuffin, L. J., Bryson, K., Buxton, B. F. and Jones, D. T. (2004) The DISOPRED server for the prediction of protein disorder. Bioinformatics, 20 (13). pp. 2138-2139. ISSN 1460-2059 doi: 10.1093/bioinformatics/bth195

Ward, J. J., Sodhi, J. S., McGuffin, L. J., Buxton, B. F. and Jones, D. T. (2004) Prediction and functional analysis of native disorder in proteins from the Three Kingdoms of Life. Journal of Molecular Biology, 337 (3). pp. 635-645. ISSN 0022-2836 doi: 10.1016/j.jmb.2004.02.002

Webster, S. E., Payne, D. A., Jones, C. I., Hayes, P. D., Bell, P. R. F., Goodall, A. H. and Naylor, A. R. (2004) Anti-platelet effect of aspirin is substantially reduced after administration of heparin during carotid endarterectomy. Journal of Vascular Research, 40 (3). pp. 463-468. ISSN 1018-1172 doi: 10.1016/j.jvs.2004.06.022

2003

Arnold, D. L., Pitman, A. and Jackson, R. W. (2003) Pathogenicity and other genomic islands in plant pathogenic bacteria. Molecular Plant Pathology, 4 (5). pp. 407-420. ISSN 1464-6722 doi: 10.1046/j.1364-3703.2003.00187.x

Browning, K., Carpenter, E., Watson, K., Coggins, J., Hawkins, A., Koch, M. and Svergun, D. (2003) Twists and turns: a tale of two shikimate-pathway enzymes. Biochemical Society Transactions, 31 (3). pp. 543-547. ISSN 1470-8752

Jones, D. T. and McGuffin, L. J. (2003) Assembling novel protein folds from super-secondary structural fragments. Proteins: Structure, Function, and Genetics, 53 (S6). pp. 480-485. ISSN 0887-3585 doi: 10.1002/prot.10542

McGuffin, L. J. and Jones, D. T. (2003) Benchmarking secondary structure prediction for fold recognition. Proteins: Structure, Function, and Genetics, 52 (2). pp. 166-175. ISSN 0887-3585 doi: 10.1002/prot.10408

McGuffin, L. J. and Jones, D. T. (2003) Improvement of the GenTHREADER method for genomic fold recognition. Bioinformatics, 19 (7). pp. 874-881. ISSN 1460-2059 doi: 10.1093/bioinformatics/btg097

Ward, J. J., McGuffin, L. J., Buxton, B. F. and Jones, D. T. (2003) Secondary structure prediction with support vector machines. Bioinformatics, 19 (13). pp. 1650-1655. ISSN 1460-2059 doi: 10.1093/bioinformatics/btg223

2002

Alderman, C. J. J., Bunyard, P. R., Chain, B. M., Foreman, J. C., Leake, D. and Katz, D. R. (2002) Effects of oxidised low density lipoprotein on dendritic cells: a possible immunoregulatory component of the atherogenic micro-environment? Cardiovascular Research, 55 (4). pp. 806-819. ISSN 0008-6363 doi: 10.1016/S0008-6363(02)00447-9

Barry, F. A. and Gibbins, J. M. (2002) Protein kinase B is regulated in platelets by the collagen receptor glycoprotein VI. The Journal of Biological Chemistry, 277 (15). pp. 12874-12878. ISSN 1083-351X doi: 10.1074/jbc.M200482200

Bicknell, K. A. and Brooks, G. (2002) Methods for delivering DNA to target tissues and cells. In: Brooks, G. (ed.) Gene Therapy: Use of DNA as a Drug. The Pharmaceutical Press, UK, pp. 23-49. ISBN 9780853694557

Brooks, G. (2002) Gene therapy. The use of DNA as a drug. The Pharmaceutical Press, pp328. ISBN 0853694559

Brooks, G. (2002) An introduction to DNA and its use in gene therapy. In: Brooks, G. (ed.) Gene Therapy: Use of DNA as a Drug. The Pharmaceutical Press, UK, pp. 1-21. ISBN 9780853694557

Chen, H., Wurm, T., Britton, P., Brooks, G. and Hiscox, J.A. (2002) Interaction of the coronavirus nucleoprotein with nucleolar antigens and the host cell. Journal of Virology, 76 (10). pp. 5233-5250. ISSN 0022-538X doi: 10.1128/JVI.76.10.5233-5250.2002

Cicmil, M., Thomas, J., Leduc, M., Bon, C. and Gibbins, J. (2002) Platelet endothelial cell adhesion molecule-1 signaling inhibits the activation of human platelets. Blood, 99 (1). pp. 137-144. ISSN 0006-4971 doi: 10.1182/blood.V99.1.137

Gibbins, J. M. (2002) The negative regulation of platelet function: extending the role of the ITIM. Trends in Cardiovascular Medicine, 12 (5). pp. 213-219. ISSN 1050-1738

Mahadeva, H., Brooks, G., Chong, N.W., Lodwick, D. and Samani, N.J. (2002) ms1, a novel stress-responsive, muscle-specific gene that is up-regulated in the early stages of pressure overload-induced left ventricular hypertrophy. FEBS Letters, 521 (1-3). pp. 100-104. ISSN 0014-5793

McGuffin, L. J. and Jones, D. T. (2002) Targeting novel folds for structural genomics. Proteins: Structure, Function, and Bioinformatics, 48 (1). pp. 44-52. ISSN 1097-0134 doi: 10.1002/prot.10129

VARA, D.J., MOVASSAGH, M. and Brooks, G. (2002) Gene therapy for the treatment of cardiovascular diseases. In: Brooks, G. (ed.) Gene Therapy: Use of DNA as a Drug. The Pharmaceutical Press, UK, pp. 135-188.

2001

Hiscox, J.A., Wurm, T., Wilson, L., Britton, P., Cavanagh, D. and Brooks, G. (2001) The coronavirus infectious bronchitis virus nucleoprotein localizes to the nucleolus. Journal of Virology, 75 (1). pp. 506-512. ISSN 0022-538X doi: 10.1128/JVI.75.1.506-512.2001

Luke, G. (2001) Education, engineering and enlightenment; the three e’s. State and home education. Home School Researcher, 14 (4). pp. 13-23.

McGuffin, L. J., Bryson, K. and Jones, D. T. (2001) What are the baselines for protein fold recognition? Bioinformatics, 17 (1). pp. 63-72. ISSN 1460-2059 doi: 10.1093/bioinformatics/17.1.63

Wurm, T., Chen, H., Hodgson, T., Britton, P., Brooks, G. and Hiscox, J.A. (2001) Localization to the nucleolus is a common feature of coronavirus nucleoproteins and the protein may disrupt host cell division. Journal of Virology, 75 (19). pp. 9345-9356. ISSN 0022-538X doi: 10.1128/JVI.75.19.9345-9356.2001

2000

Berlanga, O., Bobe, R., Becker, M., Murphy, G., Leduc, M., Bon, C., Barry, F., Gibbins, J., Garcia, P., Frampton, J. and Watson, S. P. (2000) Expression of the collagen receptor glycoprotein VI during megakaryocyte differentiation. Blood, 96 (8). pp. 2740-2745. ISSN 0006-4971

Cicmil, M., Thomas, J. M., Sage, T., Barry, F. A., Leduc, M., Bon, C. and Gibbins, J. (2000) Collagen, convulxin, and thrombin stimulate aggregation-independent tyrosine phosphorylation of CD31 in platelets. Evidence for the involvement of Src family kinases. The Journal of biological chemistry, 275 (35). pp. 27339-27347. ISSN 0021-9258 doi: 10.1074/jbc.M003196200

McGuffin, L. J., Bryson, K. and Jones, D. T. (2000) The PSIPRED protein structure prediction server. Bioinformatics, 16 (4). pp. 404-405. ISSN 1460-2059 doi: 10.1093/bioinformatics/16.4.404

1999

Brooks, G. and La Thangue, N.B. (1999) The cell cycle and drug discovery: The promise and the hope. Drug Discovery Today, 4 (10). pp. 455-463. ISSN 1359-6446 doi: 10.1016/S1359-6446(99)01400-2

Li, J.-M. and Brooks, G. (1999) Cell regulatory molecules and the cardiovascular system: Potential targets for therapy. European Heart Journal, 20 (6). pp. 406-420. ISSN 0195-668X doi: 10.1053/euhj.1998.1308

Luke, G. and Holland, P.W. (1999) Amphioxus type I keratin cDNA and the evolution of intermediate filament genes. Journal of Experimental Zoology Part a-Comparative Experimental Biology, 285 (1). pp. 50-56. ISSN 0022-104X doi: 10.1002/(SICI)1097-010X(19990415)285:1<50::AID-JEZ6>3.0.CO;2-C

Mountford, J. C., Melford, S. K., Bunce, C. M., Gibbins, J. and Watson, S. P. (1999) Collagen or collagen-related peptide cause (Ca2+)i elevation and increased tyrosine phosphorylation in human megakaryocytes. Thrombosis and haemostasis, 82 (3). pp. 1153-1159. ISSN 0340-6245

Poolman, R.A., Li, J.-M., Durand, B. and Brooks, G. (1999) Altered expression of cell cycle proteins and prolonged duration of cardiac myocyte hyperplasia in p27KIP1 knockout mice. Circulation Research, 85 (2). pp. 117-127. ISSN 0009-7330

1998

Atsumi, T., Khamashta, M.A., Haworth, R.S., Brooks, G., Amengual, O., Ichiawa, K., Koike, T. and Hughes, G.R.V. (1998) Arterial disease and thrombosis in the antiphospholipid syndrome (APS): A pathogenic role for endothelin-1 (ET-1). Arthritis and Rheumatism, 41 (5). pp. 800-807. ISSN 0004-3591 doi: 10.1002/1529-0131(199805)41:5<800::AID-ART5>3.0.CO;2-J

Brooks, G. (1998) Biotechnology in healthcare: an introduction to biopharmaceuticals. The Pharmaceutical Press, pp228. ISBN 0853693722

Brooks, G. (1998) Transgenic animals as a source of biopharmaceuticals. In: Brooks, G. (ed.) Biotechnology in Healthcare: An Introduction to Biopharmaceuticals. The Pharmaceutical Press, UK, pp. 131-146. ISBN 9780853693727

Brooks, G. (1998) An introduction to basic molecular biology. In: Brooks, G. (ed.) Biotechnology in Healthcare: An Introduction to Biopharmaceuticals. The Pharmaceutical Press, UK, pp. 1-15. ISBN 9780853693727

Brooks, G. (1998) The polymerase chain reaction (PCR): General applications and potential for clinical use. In: Brooks, G. (ed.) Biotechnology in Healthcare: An Introduction to Biopharmaceuticals. The Pharmaceutical Press, UK, pp. 61-81. ISBN 9780853693727

Brooks, G. and Vile, R. (1998) Gene therapy for the treatment of disease. In: Brooks, G. (ed.) Biotechnology in Healthcare: An Introduction to Biopharmaceuticals. The Pharmaceutical Press, UK, pp. 83-116. ISBN 9780853693727

Brooks, G., Poolman, R.A. and Li, J.-M. (1998) Arresting developments in the cardiac myocyte cell cycle: Role of cyclin-dependent kinase inhibitors. Cardiovascular Research, 39 (2). pp. 301-311. ISSN 0008-6363 doi: 10.1016/S0008-6363(98)00125-4

Galinanes, M., Goss, M.W., McGill, C.J., Hearse, D.J. and Brooks, G. (1998) Diacylglycerol-induced protection against injury during ischemia and reperfusion can be achieved without activation of protein kinase C in the rat heart: Comparative studies with ischemic preconditioning. International Journal of Cardiology, 65 (2). pp. 129-138. ISSN 0167-5273 doi: 10.1016/S0167-5273(98)00108-9

Gibbins, J., Briddon, S., Shutes, A., van Vugt, M. J., van de Winkel, J. G., Saito, T. and Watson, S. P. (1998) The p85 subunit of phosphatidylinositol 3-kinase associates with the Fc receptor gamma-chain and linker for activitor of T cells (LAT) in platelets stimulated by collagen and convulxin. The Journal of biological chemistry, 273 (51). pp. 34437-34443. ISSN 0021-9258

Haworth, R.S., Brooks, G., Cummins, P., Dobie, K., Chilton, D.C. and Avkiran, M. (1998) Differential changes in transforming growth factor β isoform expression during postnatal cardiac growth. Biochemical and biophysical research communications, 245 (3). pp. 923-927. ISSN 0006-291X doi: 10.1006/bbrc.1998.8528

Li, J.-M., Poolman, R.A. and Brooks, G. (1998) Role of G1 phase cyclins and cyclin dependent kinases during hypertrophic growth of adult rat cardiomyocytes. American Journal of Physiology-Heart and Circulatory Physiology, 275 (3 Part 2). H814-H822. ISSN 0363-6135

Patton, S.J., Luke, G. and Holland, P.W. (1998) Complex history of a chromosomal paralogy region: insights from amphioxus aromatic amino acid hydroxylase genes and insulin-related genes. Molecular Biology and Evolution, 15 (11). pp. 1373-1380. ISSN 1537-1719

Poolman, R.A. and Brooks, G. (1998) Expressions and activities of cell cycle regulatory molecules during the transition from myocyte hyperplasia to hypertrophy. Journal of Molecular and Cellular Cardiology, 30 (10). pp. 2121-2135. ISSN 0022-2828 doi: 10.1006/jmcc.1998.0808

Poolman, R.A., Gilchrist, R. and Brooks, G. (1998) Cell cycle profiles and expression of p21CIP1 and P27KIP1 during myocyte development. International Journal of Cardiology, 67 (1). pp. 133-142. ISSN 0167-5273 doi: 10.1016/S0167-5273(98)00320-9

Watson, S. P. and Gibbins, J. (1998) Collagen receptor signalling in platelets: extending the role of the ITAM. Immunology today, 19 (6). pp. 260-264. ISSN 0167-5699

1997

Asselin, J., Gibbins, J., Achison, M., Lee, Y. H., Morton, L. F., Farndale, R. W., Barnes, M. J. and Watson, S. P. (1997) A collagen-like peptide stimulates tyrosine phosphorylation of syk and phospholipase C gamma2 in platelets independent of the integrin alpha2beta1. Blood, 89 (4). pp. 1235-1242. ISSN 0006-4971

Brooks, G., Goss, M.W., Rozengurt, E. and Galinanes, M. (1997) Phorbol ester, but not ischemic preconditioning, activates protein kinase D in the rat heart. Journal of Molecular and Cellular Cardiology, 29 (8). pp. 2273-2284. ISSN 0022-2828 doi: 10.1006/jmcc.1997.0466

Brooks, G., Poolman, R.A., McGill, C.J. and Li, J.-M. (1997) Expression and activities of cyclins and cyclin-dependent kinases in developing rat ventricular myocytes. Journal of Molecular and Cellular Cardiology, 29 (8). pp. 2261-2271. ISSN 0022-2828 doi: 10.1006/jmcc.1997.0471

Gibbins, J., Okuma, M., Farndale, R., Barnes, M. and Watson, S. P. (1997) Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor gamma-chain. FEBS letters, 413 (2). pp. 255-259. ISSN 0014-5793

Haworth, R.S., Yasutake, M., Brooks, G. and Avkiran, M. (1997) Cardiac Na+/H+ exchanger during post-natal development in the rat: Changes in mRNA expression and sarcolemmal activity. Journal of Molecular and Cellular Cardiology, 29 (1). pp. 321-332. ISSN 0022-2828 doi: 10.1006/jmcc.1996.0277

Li, J.-M. and Brooks, G. (1997) Differential protein expression and subcellular distribution of TGFβ1, β2 and β3 in cardiomyocytes during pressure overload-induced hypertrophy. Journal of Molecular and Cellular Cardiology, 29 (8). pp. 2213-2224. ISSN 0022-2828 doi: 10.1006/jmcc.1997.0457

Li, J.-M. and Brooks, G. (1997) Downregulation of cyclin-dependent kinase inhibitors p21 and p27 in pressure-overload hypertrophy. American Journal of Physiology-Heart and Circulatory Physiology, 273 (2). H1358-H1367. ISSN 0363-6135

McGill, C.J. and Brooks, G. (1997) Expression and regulation of 80K/MARCKS, a major substrate of protein kinase C, in the developing rat heart. Cardiovascular Research, 34. pp. 368-376. ISSN 0008-6363 doi: 10.1016/S0008-6363(97)00041-2

Poole, A., Gibbins, J., Turner, M., van Vugt, M. J., van de Winkel, J. G., Saito, T., Tybulewicz, V. L. and Watson, S. P. (1997) The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen. The EMBO journal, 16 (9). pp. 2333-2341. ISSN 0261-4189

Poolman, R.A. and Brooks, G. (1997) Braking the cardiac myocyte cell cycle: Role of cyclin-dependent kinase inhibitors. British Society for Cardiovascular Research Bulletin, 10 (1). pp. 4-10.

Simkiss, K. and Luke, G. (1997) Ballistic transfection of avian primordial germ cells in ovo. In: Houdebine, L. M. (ed.) Transgenic animals: generation and use. CRC Press, London. ISBN 9789057020681

1996

Brooks, G. and Hearse, D.J. (1996) Role of protein kinase C in ischemic preconditioning: Player or spectator? Circulation Research, 79 (3). pp. 628-631. ISSN 0009-7330

Brooks, G., Brooks, S.F. and Goss, M.W. (1996) MARCKS functions as a novel growth/tumour suppressor in cells of melanocyte origin. Carcinogenesis, 17 (4). pp. 683-689. ISSN 0143-3334 doi: 10.1093/carcin/17.4.683

Gibbins, J., Asselin, J., Farndale, R., Barnes, M., Law, C. L. and Watson, S. P. (1996) Tyrosine phosphorylation of the Fc receptor gamma-chain in collagen-stimulated platelets. The Journal of biological chemistry, 271 (30). pp. 18095-18099. ISSN 0021-9258

Gibbins, J., Woods, R. and Lowry, P. (1996) Affinity purification of 61- and 65-kDa rat brain corticotropin-releasing factor receptors and receptor-associated G proteins. The international journal of biochemistry & cell biology, 28 (9). pp. 1017-1029. ISSN 1357-2725

Robinson, A., Gibbins, J., Rodríguez-Liñares, B., Finan, P. M., Wilson, L., Kellie, S., Findell, P. and Watson, S. P. (1996) Characterization of Grb2-binding proteins in human platelets activated by Fc gamma RIIA cross-linking. Blood, 88 (2). pp. 522-530. ISSN 0006-4971

Simkiss, K., Luke, G. and Behnam, J. (1996) Female chromosomes in cockerel ejaculates. Proceedings of the Royal Society B-Biological Science, 263 (1374). pp. 1245-1249. ISSN 0962-8452 doi: 10.1098/rspb.1996.0183

Woods, R., David, J., Baigent, S., Gibbins, J. and Lowry, P. (1996) Elevated levels of corticotrophin-releasing factor binding protein in the blood of patients suffering from arthritis and septicaemia and the presence of novel ligands in synovial fluid. British journal of rheumatology, 35 (2). pp. 120-124. ISSN 0263-7103

1995

Brooks, G. (1995) The use of transgenic animals in medicine, surgery and pharmaceuticals. BioAccess, 1 (3). pp. 10-13.

McGill, C.J. and Brooks, G. (1995) Cell cycle control mechanisms and their role in cardiac growth. Cardiovascular Research, 30 (4). pp. 557-569. ISSN 0008-6363

1994

Bresler, M., Behnam, J., Luke, G. and Simkiss, K. (1994) Manipulations of germ-cell populations in the gonad of the fowl. British Poultry Science, 35 (2). pp. 241-247. ISSN 1466-1799 doi: 10.1080/00071669408417688

Brooks, G. (1994) Gene therapy. Pharmaceutical Journal, 252. pp. 256-260. ISSN 0031-6873

Brooks, G. (1994) Transgenic animals. Pharmaceutical Journal, 253 (6802). pp. 227-231. ISSN 0031-6873

Brooks, G. (1994) The role of 80K/MARCKS, a specific substrate of protein kinase C, in cell growth and tumour progression. Pigment Cell Research, 7 (6). pp. 451-457. ISSN 0893-5785 doi: 10.1111/j.1600-0749.1994.tb00074.x

Goss, M.W. and Brooks, G. (1994) The polymerase chain reaction. Pharmaceutical Journal, 253. pp. 884-889. ISSN 0031-6873

Woods, R., Kennedy, K. M., Gibbins, J., Behan, D., Vale, W. and Lowry, P. (1994) Corticotropin-releasing factor binding protein dimerizes after association with ligand. Endocrinology, 135 (2). pp. 768-773. ISSN 0013-7227

1993

Brooks, G., Goss, M.W., East, J.A. and Hart, I.R. (1993) Growth of melanocytic cells is associated with down-regulation of protein kinase C α,δ and ε isoforms: Possible role of diacylglycerol. The Journal of Biological Chemistry, 268. pp. 23868-23875. ISSN 1083-351X

Lane, B. G., Dunwell, J. M., Ray, J. A., Schmitt, M. R. and Cuming, A. C. (1993) Germin, a protein marker of early plant development, is an oxalate oxidase. The Journal of Biological Chemistry, 268 (17). pp. 12239-12242. ISSN 1083-351X

Simkiss, K., Li, Y., Luke, G., Page, N. and Vick, V. (1993) The production of transgenic birds from primordial germ cell manipulated embryos. In: Sharp, P.J. (ed.) Avian Endocrinology. Society for Endocrinology, Bristol. ISBN 9781898099017

Vick, L., Luke, G. and Simkiss, K. (1993) Germ-line chimaeras can produce both strains of fowl with high efficiency after partial sterilization. Journal of Reproduction and Fertility, 98 (2). pp. 637-641. ISSN 1741-7899 doi: 10.1530/jrf.0.0980637

1992

Brooks, G. and Hart, I.R. (1992) Signal transduction mechanisms involved in melanocytic cell growth and progression. In: Spandidos, D.A. (ed.) Current Perspectives on Molecular and Cellular Oncology. JAI Press Ltd, London, pp. 175-209.

Brooks, G., Goss, M.W. and Hart, I.R. (1992) Differential induction of 12-O-tetradecanoylphorbol 13-acetate sequence gene expression in murine melanocytes and melanoma cells. Molecular Carcinogenesis, 5 (4). pp. 328-333. ISSN 0899-1987 doi: 10.1002/mc.2940050414

1991

Brooks, G., Wilson, R.E., Dooley, T.P., Goss, M.W. and Hart, I.R. (1991) Protein kinase C down-regulation, and not transient activation, correlates with melanocyte growth. Cancer Research, 51. pp. 3281-3288. ISSN 0008-5472

Page, N., Savva, D., Luke, G. and Simkiss, K. (1991) Transfection of chick cells by non-retroviral DNA. Biochemical Society Transactions, 19 (3). 328S. ISSN 1470-8752

1990

Brooks, G. (1990) Drug-induced photosensitivity. Pharmaceutical Journal, 245. pp. 19-21. ISSN 0031-6873

Brooks, G. and Brooks, S.F. (1990) Both tumour-promoting and non-promoting phorbol esters inhibit 125I-EGF binding and stimulate the phosphorylation of a 80kd protein kinase C substrate protein in intact Swiss 3T3 cells. Carcinogenesis, 11 (4). pp. 667-672. ISSN 0143-3334 doi: 10.1093/carcin/11.4.667

Brooks, G. and Evans, F.J. (1990) Toxic hazards of plants from the families Euphorbiaceae and Thymelaeaceae. In: Rizk, A.-F. (ed.) Poisonous Plant Contamination of Edible Plants. CRC Press, Boca Raton, USA, pp. 27-63. ISBN 9780849363696

Brooks, G., Birch, M. and Hart, I.R. (1990) Effects of biologically active tumour-promoting and non-promoting phorbol esters on in vivo growth of melanocytic cells. Pigment Cell Research, 3 (2). pp. 98-100. ISSN 0893-5785 doi: 10.1111/j.1600-0749.1990.tb00328.x

Brooks, G., Evans, A.T., Aitken, A., Evans, F.J., Rizk, A.-F., Hammouda, F.M., El-Missery, M.M. and Ismail, S.E. (1990) Daphnane diterpenes of Thymelaea hirsuta. Phytochemistry, 29 (7). pp. 2235-2237. ISSN 0031-9422 doi: 10.1016/0031-9422(90)83044-2

Brooks, G., Evans, A.T., Markby, D.P., Harrison, M.E., Baldwin, M.A. and Evans, F.J. (1990) An ingenane diterpene from Belizian Mabea excelsa. Phytochemistry, 29 (5). pp. 1615-1617. ISSN 0031-9422 doi: 10.1016/0031-9422(90)80132-Z

Brooks, G., Goss, M.W. and Hart, I.R. (1990) Inhibition of 125I-epidermal growth factor binding to murine fibroblasts and keratinocytes by irradiation with ultraviolet-B light. Carcinogenesis, 11 (7). pp. 1223-1227. ISSN 0143-3334 doi: 10.1093/carcin/11.7.1223

Evans, A.T., Brooks, G. and Evans, F.J. (1990) Non-promoting diterpene esters can induce Epstein-Barr Virus early antigen expression in the Raji cell line. Cancer Letters, 49 (1). pp. 25-29. ISSN 0304-3835 doi: 10.1016/0304-3835(90)90135-K

1989

Brooks, G., Evans, A.T., Aitken, A. and Evans, F.J. (1989) Tumour-promoting and hyperplastic effects of phorbol and daphnane esters in CD-1 mouse skin and a synergistic effect of calcium ionophore with a non-promoting activator of protein kinase C. Carcinogenesis, 10 (2). pp. 283-288. ISSN 0143-3334

Markby, D.P., Brooks, G., Evans, A.T. and Evans, F.J. (1989) The poison sap tree and its pro-inflammatory constituent: a potent activator of protein kinase C. Lancet, 8560. p. 1320. ISSN 0140-6736

1988

Brooks, G., Morrice, N., Aitken, A. and Evans, F.J. (1988) Partial synthesis of the phorbol ester probe, Sapintoxin D. Phytochemistry, 27 (5). pp. 1523-1524. ISSN 0031-9422

1987

Brooks, G., Evans, A.T., Aitken, A. and Evans, F.J. (1987) Sapintoxin A, a fluorescent phorbol ester that is a potent activator of protein kinase C but is not a tumour promoter. Cancer Letters, 38. pp. 165-170. ISSN 0304-3835

Brooks, G., Evans, A.T., Morrice, N., Ellis, C., Aitken, A. and Evans, F.J. (1987) Toxic phorbol esters from Chinese Tallow (Sapium sebiferum L.Roxb.). Toxicon, 25 (11). pp. 1229-1233. ISSN 0041-0101 doi: 10.1016/0041-0101(87)90141-3

Edwards, M.C., Williamson, E.M., Foumokong, E., Brooks, G. and Evans, F.J. (1987) Secretion and properties of a polypeptide factor generated by phorbol ester stimulation of human blood platelets. Biochemical Pharmacology, 36 (14). pp. 2418-2420. ISSN 0006-2952 doi: 10.1016/0006-2952(87)90613-7

Ellis, C.A., Brooks, S.F., Brooks, G., Evans, A.T., Morrice, N., Evans, F.J. and Aitken, A. (1987) The effects of phorbol esters with different activities on protein kinase C. Phytotherapy Research, 1 (4). 187 -192. ISSN 0951-418X doi: 10.1002/ptr.2650010412

1976

Dunwell, J. M. and Sunderland, N. (1976) Pollen ultrastructure in anther cultures of Datura innoxia. II. The generative-cell wall. Journal of Cell Science, 22 (3). pp. 481-491. ISSN 0021-9533

This list was generated on Wed Nov 26 13:18:14 2014 GMT.

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