Items where Division is "Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy"
Number of items at this level: 512. AAal, A.A., Khutoryanskiy, V.V., Nurkeeva, Z.S. and Mun, G.A. (2007) Optimization of electroless copper plating on polyethylene films modified by surface grafting of vinyl ether of monoethanolamine. Eurasian Chemico-Technological Journal, 9 (1). pp. 63-70. ISSN 1562-3920 Acton, A. L., Fante, C., Flatley, B., Burattini, S., Hamley, I. W., Wang, Z., Greco, F. and Hayes, W. (2013) Janus PEG-based dendrimers for use in combination therapy: controlled multi-drug loading and sequential release. Biomacromolecules, 14 (2). pp. 564-574. ISSN 1525-7797 doi: 10.1021/bm301881h Ahmed, A., Barry, B. W., Williams, A. C. and Davis, A. F. (2004) Penciclovir solubility in Eudragit films: a comparison of X-ray, thermal, microscopic and release rate techniques. Journal of Pharmaceutical and Biomedical Analysis, 34. pp. 945-956. ISSN 0731-7085 doi: 10.1016/j.jpba.2003.11.018 Aili, C., Nilsson, L.E., Svensson, L.G. and Denicolo, P.M., eds. (2007) In tension between organization and profession. Nordic Academic Press, Lund, Sweden. ISBN 9789185509027 Aitchison, E., Weston, S. E., Constanti, A. and Whalley, B. J. (2010) Anticholinesterase-induced epileptiform activity in immature rat piriform cortex slices, in vitro. Neuroscience Letters, 473 (3). pp. 252-256. ISSN 0304-3940 doi: 10.1016/j.neulet.2010.02.060 Al-Owais, M. M. A., Scragg, J. L., Dallas, M. L., Boycott, H. E., Warburton, P., Chakrabarty, A., Boyle, J. P. and Peers, C. (2012) Carbon monoxide mediates the anti-apoptotic effects of heme oxygenase-1 in medulloblastoma DAOY cells via K+ channel inhibition. The Journal of Biological Chemistry, 287 (29). pp. 24754-24764. ISSN 1083-351X doi: 10.1074/jbc.M112.357012 Al-Saadi , A., Yu , C.H., Khutoryanskiy, V. V., Shih , S.-J., Crossley , A. and Tsang , S.C. (2009) Layer-by-layer electrostatic entrapment of protein molecules on superparamagnetic nanoparticle: new strategy to enhance adsorption capacity and maintain biological activity. Journal of Physical Chemistry C, 113 (34). pp. 15260-15265. ISSN 1932-7447 doi: DOI:10.1021/jp903100j Alemi, F., Kwon, E., Poole, D. P., Lieu, T., Lyo, V., Cattaruzza, F., Cevikbas, F., Steinhoff, M., Nassini, R., Materazzi, S., Guerrero-Alba, R., Valdez-Morales, E., Cottrell, G., Schoonjans, K., Geppetti, P., Vanner, S. J., Bunnett, N. W. and Corvera, C. U. (2013) The TGR5 receptor mediates bile acid-induced itch and analgesia. The Journal of Clinical Investigation, 123 (4). pp. 1513-1530. ISSN 0021-9738 doi: 10.1172/JCI64551 Alexander, A. (2006) Pharmacy and prescribing. In: Brookes, D. and Smith, A. (eds.) Non-medical prescribing in healthcare practice: a toolkit for students and practitioners. Palgrave Macmillan, Basingstoke, pp. 149-163. ISBN 9781403990648 Alexander, A., Denicolo, P. and Donyai, P. (2011) Purpose-Action-Results as a behavioural model: telling the story of pharmacy professionals’ continuing professional development. International Journal of Pharmacy Practice, 19 (S1). p. 13. ISSN 0961-7671 Aley, P. K., Bauer, C. C., Dallas, M. L., Boyle, J. P., Porter, K. E. and Peers, C. (2009) Hypoxic modulation of ca(2+) signaling in human venous and arterial endothelial cells. The Journal of Membrane Biology, 227 (3). pp. 151-158. ISSN 1432-1424 doi: 10.1007/s00232-008-9147-z Ali, W., Williams, A. C. and Rawlinson, C. F. (2010) Stochiometrically governed molecular interactions in drug: Poloxamer solid dispersions. International Journal of Pharmaceutics, 391 (1-2). pp. 162-168. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2010.03.014 Allsup, S., Haycox, A., Regan, M. and Gosney, M. (2004) Is influenza vaccination cost effective for healthy people between ages 65 and 74 years? A randomised controlled trial. Vaccine, 23 (5). pp. 639-645. ISSN 0264-410X doi: 10.1016/j.vaccine.2004.07.008 Amadesi, S., Cottrell, G. S., Divino, L., Chapman, K., Grady, E. F., Bautista, F., Karanjia, R., Barajas-Lopez, C., Vanner, S., Vergnolle, N. and Bunnett, N. W. (2006) Protease-activated receptor 2 sensitizes TRPV1 by protein kinase Cepsilon- and A-dependent mechanisms in rats and mice. Journal of Physiology, 575 (2). pp. 555-571. ISSN 0022-3751 doi: 10.1113/jphysiol.2006.111534 Amadesi, S., Grant, A. D., Cottrell, G., Vaksmam, N., Poole, D. P., Rozengurt, E. and Bunnett, N. W. (2009) Protein kinase D isoforms are expressed in rat and mouse primary sensory neurons and are activated by agonists of protease-activated receptor 2. Journal of Comparative Neurology, 516 (2). pp. 141-156. ISSN 1096-9861 doi: 10.1002/cne.22104 Amadesi, S., Nie, J., Vergnolle, N., Cottrell, G. S., Grady, E. F., Trevisani, M., Manni, C., Geppetti, P., McRoberts, J. A., Ennes, H., Davis, J. B., Mayer, E. A. and Bunnett, N. W. (2004) Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia. The Journal of Neuroscience, 24 (18). pp. 4300-4312. ISSN 1529-2401 doi: 10.1523/JNEUROSCI.5679-03.2004 Anderson, D. B., Cimarosti, H. I. and Henley, J. M. (2009) The role of sumoylation in neurodegenerative diseases. In: Wilson, V. G. (ed.) SUMO regulation of cellular processes. Springer, pp. 233-251. ISBN 9789048126484 doi: 10.1007/978-90-481-2649-1_14 Aravindan, L. , Bicknell, K. A., Brooks, G., Khutoryanskiy, V. V. and Williams, A. C. (2009) Effect of acyl chain length on transfection efficiency and toxicity of polyethylenimine. International Journal of Pharmaceutics, 378 (1-2). pp. 201-210. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2009.05.052 Arlin, J.-B., Kennedy, A. R. and Shankland, K. (2012) Magnesium, calcium and strontium salts of phenylacetic acid. Acta Crystallographica Section C Crystal Structure Communications, 68. M29-M33. ISSN 0108-2701 doi: 10.1107/S0108270111055284 Avery, A. A., Barber, N., Ghaleb, M., Dean Franklin, B., Armstrong, S., Crowe, S., Dhillon, S., Freyer, A., Howard, R., Pezzolesi, C., Serumaga, B., Swanwick, G. and Olanrewaju, T. (2012) Investigating the prevalence and causes of prescribing errors in general practice: the PRACtICe Study. Project Report. General Medical Council pp227. Avery, A. A., Rodgers, S., Cantrill, J. A., Armstrong, S., Cresswell, K., Eden, M., Elliott, R. A., Howard, R., Kendick, D., Morris, C. J., Prescott, R. J., Swanwick, G., Franklin, M., Putman, K., Boyd, M. and Sheikh, A. (2012) A pharmacist-led information technology intervention for medication errors (PINCER): a multicentre, cluster randomised, controlled trial and cost-effectiveness analysis. The Lancet, 379 (9823). pp. 1310-1319. ISSN 0140-6736 doi: 10.1016/S0140-6736(11)61817-5 Avery, A. J., Rodgers, S., Cantrill, J. A., Armstrong, S., Boyd, M., Cresswell, K., Eden, M., Elliott, R., Franklin, M., Hippisley-Cox, J., Howard, R., Kendrick, D., Morris, C. J., Murray, S. A., Prescott, R. J., Puttman, K., Swanwick, G., Tuersley, L., Turner, T., Vinogradova, Y. and Sheikh, A. (2010) PINCER trial: a cluster randomised trial comparing the effectiveness and cost-effectiveness of a pharmacist-led IT-based intervention with simple feedback in reducing rates of clinically important errors in medicines management in general practices. Project Report. Patient Safety Research Portfolio, Birmingham. Avery, A.J., Rodgers, S., Cantrill, J.A., Armstrong, S., Elliott, R., Howard, R., Kendrick, D., Morris, C.J., Murray, S.A., Prescott, R.J., Cresswell, K. and Sheikh, A. (2009) Protocol for the PINCER trial: a cluster randomised trial comparing the effectiveness of a pharmacist-led IT-based intervention with simple feedback in reducing rates of clinically important errors in medicines management in general practices. Trials, 10 (28). ISSN 1745-6215 doi: 10.1186/1745-6215-10-28 BBahia, P. K., Pugh, V., Hoyland, K., Hensley, V., Rattray, M. and Williams, R. J. (2012) Neuroprotective effects of phenolic antioxidant tBHQ associate with inhibition of FoxO3a nuclear translocation and activity. Journal of Neurochemistry, 123 (1). pp. 182-191. ISSN 0022-3042 doi: 10.1111/j.1471-4159.2012.07877.x Bahia, P.K., Rattray, M. and Williams, R.J. (2008) Dietary flavonoid (-)epicatechin stimulates phosphatidylinositol 3-kinase-dependent anti-oxidant response element activity and up-regulates glutathione in cortical astrocytes. Journal of Neurochemistry, 106 (5). pp. 2194-2204. ISSN 0022-3042 doi: 10.1111/j.1471-4159.2008.05542.x Baillie, G. L. , Horswill, J., Anavi-Goffer,, S. , Reggio, P. H. , Bolognini , D. , Abood, M. E. , McAllister, S. , Strange, P., Stephens, G., Pertwee, R. G. and Ross, R. A. (2013) CB1 receptor allosteric modulators display both agonist and signaling pathway specificity. Molecular Pharmacology, 82 (2). pp. 322-338. ISSN 1521-0111 doi: 10.1124/mol.112.080879 Baksh, M. F. and Kelly, P. (2008) Statistical methods for examining genetic influences of resistance to anti-epileptic drugs. Expert Review of Clinical Pharmacology, 1 (1). pp. 137-144. ISSN 1751-2433 doi: 10.1586/17512433.1.1.137 Bannon, J.H., Fichtner, I., O'Neill, A., Pampillon, C., Sweeney, N.J., Strohfeldt, K., Watson, R.W., Tacke, M. and McGee, M.M. (2007) Substituted titanocenes induce caspase-dependent apoptosis in human epidermoid carcinoma cells in vitro and exhibit antitumour activity in vivo. British Journal of Cancer, 97 (9). pp. 1234-1241. ISSN 0007-0920 doi: 10.1038/sj.bjc.6604021 Barbara, G., Stanghellini, V., De Giorgio, R., Cremon, C., Cottrell, G. S., Santini, D., Pasquinelli, G., Morselli-Labate, A. M., Grady, E. F., Bunnett, N. W., Collins, S. M. and Corinaldesi, R. (2004) Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome. Gastroenterology, 126 (3). pp. 693-702. ISSN 0016-5085 doi: 10.1053/j.gastro.2003.11.055 Barclay, W.S., Jones, I.M., Osborn, H.M.I., Phillipson, L., Ren, J.Y., Talevera, G.A. and Thompson, C.I. (2007) Probing the receptor interactions of an H5 avian influenza virus using a baculovirus expression system and functionalised poly(acrylic acid) ligands. Bioorganic & Medicinal Chemistry, 15 (12). pp. 4038-4047. ISSN 0968-0896 doi: 10.1016/j.bmc.2007.03.085 Barnes, J., Barber, N., Wheatley, D. and Williamson, E.M. (2006) A pilot randomised, open, uncontrolled, clinical study of two dosages of St John's wort (Hypericum perforatum) herb extract (LI-160) as an aid to motivational/behavioural support in smoking cessation. Planta Medica, 72 (4). pp. 378-382. ISSN 0032-0943 doi: 10.1055/s-2005-916219 Bateman, R. and Donyai, P. (2010) Errors associated with the preparation of aseptic products in UK hospital pharmacies: lessons from the national aseptic error reporting scheme. Quality and Safety in Health Care , 19 (5). e29. ISSN 1475-3898 doi: 10.1136/qshc.2009.034751 Bauer, J., Stiller, J., Marques-Lopez, E., Strohfeldt, K. A., Christmann, M. and Strohmann , C. (2010) Silyl-Modified Analogues of 2-Tritylpyrrolidine: Synthesis and Applications in Asymmetric Organocatalysis. Chemistry - A European Journal, 16 (42). pp. 12553-12558. ISSN 0947-6539 doi: 10.1002/chem.201002166 Becker, L.M. and Denicolo, P.M. (2008) Managing the research process and the supervisory relationship. In: Hall, G. and Longman, J. (eds.) The postgraduate’s companion. Sage, London. ISBN 9781412930253 Beckhove, P., Oberschmidt, O., Hanauske, A.R., Pampillon, C., Schirrmacher, V., Sweeney, N.J., Strohfeldt, K. and Tacke, M. (2007) Antitumor activity of Titanocene Y against freshly explanted human breast tumor cells and in xenografted MCF-7 tumors in mice. Anti-cancer Drugs, 18 (3). pp. 311-316. ISSN 0959-4973 doi: 10.1097/CAD.0b013e328010a6f7 Benning, R. K., Osborn, H. M. I. and Turkson, A. (2011) Regioselective Beckmann rearrangements of furanoside and pyranoside-derived oximes. Tetrahedron: Asymmetry, 22 (1). pp. 109-116. ISSN 0957-4166 doi: 10.1016/j.tetasy.2010.11.031 Bettio, F., Canevari, M., Marzano, C., Bordin, F., Guiotto, A., Greco, F., Duncan, R. and Veronese, F. (2006) Synthesis and biological in vitro evaluation of novel PEG-psoralen conjugates. Biomacromolecules, 7 (12). pp. 3534-3541. ISSN 1525-7797 doi: 10.1021/bm060760n Bicknell, K. A. and Brooks, G. (2008) Reprogramming the cell cycle machinery to treat cardiovascular disease. Current Opinion in Pharmacology, 8 (2). pp. 193-201. ISSN 1471-4892 doi: 10.1016/j.coph.2007.12.015 Bicknell, K. A., Coxon, C. H. and Brooks, G. (2004) Forced expression of the cyclin B1-CDC2 complex induces proliferation in adult rat cardiomyocytes. The Biochemical Journal, 382 (2). pp. 411-6. ISSN 1470-8728 Bicknell, K. A., Harmer, S. C., Yiangson, S., Lockwood, W. and Bicknell, A. B. (2009) Lys-gamma3-MSH: a global regulator of hormone sensitive lipase activity? Molecular and Cellular Endocrinology , 300 (1-2). pp. 71-76. ISSN 0303-7207 doi: 10.1016/j.mce.2008.09.032 Bicknell, K., Brooks, G., Kaiser, P., Chen, H. Y., Dove, B. K. and Hiscox, J. A. (2005) Nucleolin is regulated both at the level of transcription and translation. Biochemical and Biophysical Research Communications, 332 (3). pp. 817-822. ISSN 0006-291X doi: 10.1016/j.bbrc.2005.05.022 Bicknell, K.A., Coxon, C.N.H. and Brooks, G. (2007) Can the cardiomyocyte cell cycle be reprogrammed? Journal of Molecular and Cellular Cardiology, 42 (4). pp. 706-721. ISSN 0022-2828 doi: 10.1016/j.yjmcc.2007.01.006 Billinge, S. , Dykhne, T., Juhas, P., Bozin, E., Taylor, R., Florence, A. and Shankland, K. (2010) Characterisation of amorphous and nanocrystalline molecular materials by total scattering. Crystengcomm, 12 (5). pp. 1366-1368. ISSN 1466-8033 doi: 10.1039/b915453a Bizley, S. C., Williams, A. C., Kemp, F. and Khutoryanskiy, V. V. (2012) Optimizing layer-by-layer deposition of interpolymer complexes on solid substrates using Biacore. Soft Matter, 8 (25). pp. 2782-2787. ISSN 1744-683X doi: 10.1039/C2SM25652E Boateng, S. Y., Senyo, S. E., Qi, L. X., Goldspink, P. H. and Russell, B. (2009) Myocyte remodeling in response to hypertrophic stimuli requires nucleocytoplasmic shuttling of muscle LIM protein. Journal of Molecular and Cellular Cardiology, 47 (4). pp. 426-435. ISSN 0022-2828 doi: 10.1016/j.yjmcc.2009.04.006 Bonjoch, J., Drew, M. G.B., Gonzalez, A., Greco, F., Jawaid, S., Osborn, H. M. I., Williams, N. A.O. and Yaqoob, P. (2008) Synthesis and evaluation of novel boron-containing complexes of potential use for the selective treatment of malignant melanoma. Journal of Medicinal Chemistry, 51 (20). pp. 6604-6608. ISSN 0022-2623 doi: 10.1021/jm8007745 Boycott, H. E., Dallas, M., Boyle, J. P., Pearson, H. A. and Peers, C. (2007) Hypoxia suppresses astrocyte glutamate transport independently of amyloid formation. Biochemical and Biophysical Research Communications, 364 (1). pp. 100-104. ISSN 0006-291X doi: 10.1016/j.bbrc.2007.09.102 Brazier, J. A., Shah, A. and Brown, G. D. (2012) I-Motif formation in gene promoters: unusually stable formation in sequences complementary to known G-quadruplexes. Chemical Communication, 48 (87). pp. 10739-10741. ISSN 1359-7345 doi: 10.1039/C2CC30863K Brazier, J. A., Fisher, J. and Cosstick, R. (2005) Stabilization of the DNA I-motif structure by incorporation of 3 '-S-phosphorothiolate linkages. Angewandte Chemie-International Edition, 45 (1). pp. 114-117. ISSN 1521-3773 doi: 10.1002/anie.200503110 Brazier, J. A., Shibata, T., Townsley, J., Taylor, B. F., Frary, E., Williams, N. H. and Williams, D. M. (2005) Amino-functionalized DNA: the properties of C5-amino-alkyl substituted 2′-deoxyuridines and their application in DNA triplex formation. Nucleic Acids Research, 33 (4). pp. 1362-1371. ISSN 1362-4962 doi: 10.1093/nar/gki254 Brome, V.A., Harwood, L.M. and Osborn, H.M.I. (2006) Preparation of enantiopure long chain threo-2-amino-3-hydroxyesters via chiral morpholinone-derived azomethine ylids. Canadian Journal of Chemistry-Revue Canadienne De Chimie, 84 (10). pp. 1448-1455. ISSN 0008-4042 doi: 10.1139/v06-121 Brooks, G. (2005) Cyclins, cyclin-dependent kinases, and cyclin-dependent kinase inhibitors: detection methods and activity measurements. In: Humphrey, T. and Brooks, G. (eds.) Cell cycle control: mechanisms and protocols. Methods in molecular biology, 296. Humana Press, New Jersey, pp. 291-298. ISBN 9781588291448 doi: 10.1385/1-59259-857-9:291 Bucci, G., Mochida, S. and Stephens, G. J. (2011) Inhibition of synaptic transmission and G protein modulation by synthetic CaV2.2 Ca2+ channel peptides. Journal of Physiology, 589 (13). pp. 3085-3101. ISSN 0022-3751 doi: 10.1113/jphysiol.2010.204735 Burland, P. A., Coisson, D. and Osborn, H. M. I. (2010) Rapid synthesis of carbohydrate derivatives, including mimetics of c-linked disaccharides and c-Linked aza disaccharides, using the Hetero-Diels−Alder Reaction. Journal of Organic Chemistry, 75 (21). pp. 7210-7218. ISSN 0022-3263 doi: 10.1021/jo101219w Burland, P. A., Osborn, H. M. I. and Turkson, A. (2011) Synthesis and glycosidase inhibitory profiles of functionalised morpholines and oxazepanes. Bioorganic & Medicinal Chemistry, 19 (18). pp. 5679-5692. ISSN 0968-0896 doi: 10.1016/j.bmc.2011.07.019 CCampbell Roberts, S. N. C., Williams, A. C., Grimsey, I. M. and Booth, S. W. (2002) Quantitative analysis of mannitol polymorphs: FT-Raman spectroscopy. Journal of Pharmaceutical and Biomedical Analysis, 28. pp. 1135-1147. ISSN 0731-7085 doi: 10.1016/S0731-7085(02)00059-6 Campbell Roberts, S. N. C., Williams, A. C., Grimsey, I. M. and Booth, S. W. (2002) Quantitative analysis of mannitol polymorphs: X-ray powder diffractometry—exploring preferred orientation effects. Journal of Pharmaceutical and Biomedical Analysis, 28 (6). pp. 1149-1159. ISSN 0731-7085 doi: 10.1016/S0731-7085(02)00053-5 Carbone, M., Duty, S. and Rattray, M. (2012) Riluzole elevates GLT-1 activity and levels in striatal astrocytes. Neurochemistry International, 60 (1). pp. 31-38. ISSN 0197-0186 doi: 10.1016/j.neuint.2011.10.017 Carbone, M., Duty, S. and Rattray, M. (2012) Riluzole neuroprotection in a parkinson’s disease model involves suppression of reactive astrocytosis but not GLT-1 regulation. BMC Neuroscience, 13. 38. ISSN 1471-2202 doi: 10.1186/1471-2202-13-38 (In Press) Carlescu, I., Osborn, H. M.I., Desbrieres, J., Scutaru, D. and Popa, M. (2010) Synthesis of poly(aspartimide)-based bio-glycoconjugates. Carbohydrate Research, 345 (1). pp. 33-40. ISSN 0008-6215 doi: 10.1016/j.carres.2009.08.034 Caspers, P. J., Williams, A. C., Carter, E. A., Edwards, H. G. M., Barry, B. W., Bruining, H. A. and Pupples, G. J. (2002) Monitoring the penetration enhancer dimethyl sulfoxide in human stratum corneum in vivo by confocal raman spectroscopy. Pharmaceutical Research, 19 (10). pp. 1577-1580. ISSN 0724-8741 doi: 10.1023/A:1020481305420 Castelletto, V., Hamley, I. W., Stain, C. and Connon, C. (2012) Slow-release RGD-peptide hydrogel monoliths. Langmuir, 28 (34). pp. 12575-12580. ISSN 0743-7463 doi: 10.1021/la302071e Cave, R., Cook, J., Connon, C. J. and Khutoryanskiy, V. V. (2012) A flow system for the on-line quantitative measurement of the retention of dosage forms on biological surfaces using spectroscopy and image analysis. International Journal of Pharmaceutics, 428 (1-2). pp. 96-102. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2012.02.047 Cenac, N. ., Andrews, C. N., Holzhausen, M., Chapman, K., Cottrell, G. S., Andrade-Gordon, P., Steinhoff, M., Barbara, G., Beck, P., Bunnett, N. W., Sharkey, K. A., Ferraz, J. G., Shaffer, E. and Vergnolle, N. (2007) Role for protease activity in visceral pain in irritable bowel syndrome. The Journal of Clinical Investigation, 117 (3). pp. 636-647. ISSN 0021-9738 doi: 10.1172/JCI29255 Chai, W., Piskarev, V.E., Mulloy, B., Liu, Y., Evans, P.G., Osborn, H.M.I. and Lawson, A.M. (2006) Analysis of chain and blood group type and branching pattern of sialylated oligosaccharides by negative ion electrospray tandem mass spectrometry. Analytical Chemistry, 78 (5). pp. 1581-1592. ISSN 0003-2700 doi: 10.1021/ac051606e Chan, K., Shaw, D., Simmonds, M. S.J., Leon, C. J., Xu, Q., Lu, A., Sutherland, I., Ignatova, S., Zhu, Y.-P., Verpoorte, R., Williamson, E. M. and Duez, P. (2012) Good practice in reviewing and publishing studies on herbal medicine, with special emphasis on traditional Chinese medicine and Chinese materia medica. Journal of Ethnopharmacology, 140 (3). pp. 469-475. ISSN 0378-8741 doi: 10.1016/j.jep.2012.02.028 Chan, K., Swinden, J. and Donyai, P. (2007) Pilot study of the short-term physico-chemical stability of atenolol tablets stored in a multi-compartment compliance aid. European Journal of Hospital Pharmacy Science, 13 (3). pp. 60-66. Cheeks, M. C., Edwards, A. D., Arnot, C. J. and Slater, N. K.H. (2009) Gene transfection of HEK cells on supermacroporous polyacrylamide monoliths: a comparison of transient and stable recombinant protein expression in perfusion culture. New Biotechnology, 26 (6). pp. 289-299. ISSN 1871-6784 doi: 10.1016/j.nbt.2009.08.006 Chen, B., Jones, R. R., Mi, S., Foster, J., Alcock, S., Hamley, I. and Connon, C. (2012) The mechanical properties of amniotic membrane influence its effect as a biomaterial for ocular surface repair. Soft Matter, 8 (32). pp. 8379-8387. ISSN 1744-683X doi: 10.1039/C2SM26175H Chen, B., Mi, S., Wright, B. and Connon, C. J. (2010) Investigation of K14/K5 as a stem cell marker in the limbal region of the bovine cornea. PLoS ONE, 5 (10). e13192. ISSN 1932-6203 doi: 10.1371/journal.pone.0013192 Chen, B., Wright, B., Sahoo, R. and Connon, C. J. (2013) A novel alternative to cryopreservation for the short-term storage of stem cells for use in cell therapy using alginate encapsulation. Tissue Engineering Part C : methods. ISSN 1937-3384 doi: 10.1089/ten.tec.2012.0489 Chen, B., Mi, S., Wright, B. and Connon, C. J. (2010) Differentiation status of limbal epithelial cells cultured on intact and denuded amniotic membrane before and after air-lifting. Tissue Engineering, 16 (9). pp. 2721-2729. ISSN 1937-3341 Cheng, G., Greenland, B. W., Lampard, C., Williams, N., Bahra, M. S. and Hayes, W. (2013) Lightly branched comb polyesters: application in fast drying solvent-borne coating formulations. Reactive & Functional Polymers, 73 (4). pp. 619-623. ISSN 1381-5148 doi: 10.1016/j.reactfunctpolym.2013.01.008 Cheng, G., Castelletto, V., Jones, R. R., Connon, C. J. and Hamley, I. W. (2011) Hydrogelation of self-assembling RGD-based peptides. Soft Matter, 7 (4). pp. 1326-1333. ISSN 1744-683X doi: 10.1039/C0SM00408A Cimarosti, H. and Henley, J. M. (2008) Investigating the mechanisms underlying neuronal death in ischemia using in vitro oxygen-glucose deprivation: potential involvement of protein SUMOylation. The Neuroscientist, 14 (6 ). pp. 626-636. ISSN 1089-4098 doi: 10.1177/1073858408322677 Cimarosti, H., Ashikaga, E., Jaafari, N., Dearden , L., Rubin, P., Wilkinson, K. A. and Henley, J. M. (2012) Enhanced SUMOylation and SENP-1 protein levels following oxygen and glucose deprivation in neurones. Journal of Cerebral Blood Flow and Metabolism, 32 (1). pp. 17-22. ISSN 1559-7016 doi: 10.1038/jcbfm.2011.146 Cimarosti, H., Kantamneni, S. and Henley, J. M. (2009) Ischaemia differentially regulates GABAB receptor subunits in organotypic hippocampal slice cultures. Neuropharmacology, 56 (8). pp. 1088-1096. ISSN 0028-3908 doi: 10.1016/j.neuropharm.2009.03.007 Cimarosti, H., Lindberg, C. , Bomholt, S. F. , Rønn, L. C.B. and Henley, J. M. (2008) Increased protein SUMOylation following focal cerebral ischemia. Neuropharmacology, 54 (2). pp. 280-289. ISSN 0028-3908 doi: 10.1016/j.neuropharm.2007.09.010 Clifton, L. A., Green, R. J., Hughes, A. V. and Frazier, R. A. (2008) Interfacial structure of wild-type and mutant forms of puroindoline-b bound to DPPG monolayers. Journal of Physical Chemistry B, 112 (49). pp. 15907-15913. ISSN 1520-6106 doi: 10.1021/jp806016h Clifton, L. A., Green, R. J. and Frazier, R. A. (2007) Puroindoline-b mutations control the lipid binding interactions in mixed puroindoline-a: puroindoline-b systems. Biochemistry, 46 (48). pp. 13929-13937. ISSN 0006-2960 doi: 10.1021/bi701680w Clifton, L. A., Lad, M. D., Green, R. J. and Frazier, R. A. (2007) Single amino acid substitutions in puroindoline-b mutants influence lipid binding properties. Biochemistry, 46 (8). pp. 2260-2266. ISSN 0006-2960 doi: 10.1021/bi062190h Clifton, L. A., Sanders, M. R., Castelletto, V., Rogers, S. E., Heenan, R. K., Neylon, C., Frazier, R. and Green, R. J. (2011) Puroindoline-a, a lipid binding protein from common wheat, spontaneously forms prolate protein micelles in solution. Physical Chemistry Chemical Physics, 13 (19). pp. 8881-8888. ISSN 1463-9076 doi: 10.1039/c0cp02247k Clifton, L. A., Sanders, M. R., Hughes, A. V., Neylon, C., Frazier, R. A. and Green, R. J. (2011) Lipid binding interactions of antimicrobial plant seed defence proteins: puroindoline-a and β-purothionin. Physical Chemistry Chemical Physics, 13 (38). pp. 17153-17162. ISSN 1463-9076 doi: 10.1039/c1cp21799b Clifton, L. A., Sanders, M., Kinane, C., Arnold, T., Edler, K. J., Neylon, C., Green, R. J. and Frazier, R. A. (2012) The role of protein hydrophobicity in thionin–phospholipid interactions: a comparison of α1 and α2-purothionin adsorbed anionic phospholipid monolayers. Physical Chemistry Chemical Physics, 14 (39). pp. 13569-13579. ISSN 1463-9076 doi: 10.1039/C2CP42029E Coats, A. and Williamson, E.M. (2009) Scientific deception: retraction of a fraudulent paper. International Journal of Cardiology, 131 (3). p. 297. ISSN 0167-5273 doi: 10.1016/j.ijcard.2008.10.037 Cobb, A. (2011) General aspects of organocatalytic cyclizations. In: Mahrwald, R. (ed.) Enantioselective Organocatalyzed Reactions II: Asymmetric C-C Bond Formation Processes. Springer, pp. 1-40. ISBN 9789048138661 Cobb, A.J.A. (2007) Recent highlights in modified oligonucleotide chemistry. Organic & Biomolecular Chemistry, 5 (20). pp. 3260-3275. ISSN 1477-0520 doi: 10.1039/b709797m Cobb, A.J.A. and Ley, S.V. (2009) 5-pyrrolidin-2-yl tetrazole. In: Paquette, L.A. (ed.) Encyclopedia of reagents for organic synthesis. Wiley, Chichester. ISBN 9780470017548 Cobb, A.J.A. and Marson, C.M. (2005) Asymmetric synthesis using catalysts containing multiple stereogenic centres and a trans-1,2-diaminocyclohexane core; reversal of predominant enantioselectivity upon N-alkylation. Tetrahedron, 61 (5). pp. 1269-1279. ISSN 0040-4020 doi: 10.1016/j.tet.2004.11.030 Cobb, A.J.A., Shaw, D.M., Longbottom, D.A., Gold, J.B. and Ley, S.V. (2005) Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions. Organic & Biomolecular Chemistry, 3 (1). pp. 84-96. ISSN 1477-0520 doi: 10.1039/b414742a Connon, C. J., Doutch, J., Chen, B., Hopkinson, A., Mehta, J., Nakamura, T., Kinoshita, S. and Meek, K. (2010) The variation in transparency of amniotic membrane used in ocular surface regeneration. British Journal of Ophthalmology, 94 (8). pp. 1057-1061. ISSN 0007-1161 doi: 10.1136/bjo.2008.153064 Connon, C. J., Nakamura, T., Hopkinson, A., Quantock, A., Yagi, N., Doutch, J. and Meek, K. M. (2007) The biomechanics of amnion rupture: an X-ray diffraction study. PLoS ONE, 2 (11). e1147. ISSN 1932-6203 doi: 10.1371/journal.pone.0001147 Cook, J., Goodall, G. W., Khutoryanskaya, O. and Khutoryanskiy, V. V. (2012) Microwave-assisted hydrogel synthesis: a new method for crosslinking polymers in aqueous solutions. Macromolecular Rapid Communications, 33 (4). pp. 332-336. ISSN 1022-1336 doi: 10.1002/marc.201100742 Cook, M., Tzortzis, G. T., Khutoryanskiy, V. V. and Charalampopoulos, D. (2013) Layer-by-layer coating of alginate matrices with chitosan–alginate for the improved survival and targeted delivery of probiotic bacteria after oral administration. Journal of Materials Chemistry B, 1. pp. 52-60. doi: 10.1039/C2TB00126H Cook, M. T., Tzortzis, G., Charalampopoulos, D. and Khutoryanskiy, V. V. (2012) Microencapsulation of probiotics for gastrointestinal delivery. Journal of Controlled Release, 162 (1). pp. 56-67. ISSN 0168-3659 doi: 10.1016/j.jconrel.2012.06.003 Cook, M. T., Tzortzis, G., Charalampopoulos, D. and Khutoryanskiy, V. V. (2011) Production and evaluation of dry alginate-chitosan microcapsules as an enteric delivery vehicle for probiotic bacteria. Biomacromolecules, 12 (7). pp. 2834-2840. ISSN 1525-7797 doi: 10.1021/bm200576h Cooper, A., Kennedy, M.W., Fleming, R.I., Wokosin, D.L., Su, T.J., Green, R.J., Lu, J.R. , Wilson, E.H. and Videler, H. (2005) Adsorption of frog foam nest proteins at the air-water interface. Biophysical Journal, 88 (3). pp. 2114-2125. ISSN 0006-3495 doi: 10.1529/biophysj.104.046268 Cottrell, G. S. (2013) Roles of proteolysis in regulation of G protein-coupled receptor function. British Journal of Pharmacology, 168 (3). pp. 576-590. ISSN 1476-5381 doi: 10.1111/j.1476-5381.2012.02234.x Cottrell, G. S., Amadesi, S., Grady, E. F. and Bunnett, N. W. (2004) Trypsin IV, a novel agonist of protease-activated receptors 2 and 4. Journal of Biological Chemistry, 279 (14). pp. 13532-13539. ISSN 1083-351X doi: 10.1074/jbc.M312090200 Cottrell, G. S., Amadesi, S., Pikios, S., Camerer, E., Willardsen, J. A., Murphy, B. R., Caughey, G. H., Wolters, P. J., Coughlin, S. R., Peterson, A., Knecht, W., Pothoulakis, C., Bunnett, N. W. and Grady, E. F. (2007) Protease-activated receptor 2, dipeptidyl peptidase I, and proteases mediate Clostridium difficile toxin A enteritis. Gastroenterology, 132 (7). pp. 2422-2437. ISSN 0016-5085 doi: 10.1053/j.gastro.2007.03.101 Cottrell, G. S., Amadesi, S., Schmidlin, F. and Bunnett, N. (2003) Protease-activated receptor 2: activation, signalling and function. Biochemical Society Transactions, 31 (6). pp. 1191-1197. ISSN 1470-8752 Cottrell, G. S., Coelho, A. M. and Bunnett, N. W. (2002) Protease-activated receptors: the role of cell-surface proteolysis in signalling. Essays in Biochemistry, 38. pp. 169-183. ISSN 0071-1365 Cottrell, G. S., Hooper, N. M. and Turner, A. J. (2000) Cloning, expression, and characterization of human cytosolic aminopeptidase P: a single manganese(II)-dependent enzyme. Biochemistry, 39 (49). pp. 15121-15128. ISSN 0006-2960 doi: 10.1021/bi001585c Cottrell, G. S., Hyde, R. J., Hooper, N. M. and Turner, A. J. (1998) The cloning and functional expression of human pancreatic aminopeptidase P. Biochemical Society Transactions, 26 (3). S248. ISSN 1470-8752 Cottrell, G. S., Hyde, R. J., Lim, J., Parsons, M. R., Hooper, N. M. and Turner, A. J. (2000) Identification of critical residues in the active site of porcine membrane-bound aminopeptidase P. Biochemistry, 39 (49). pp. 15129-15135. ISSN 0006-2960 doi: 10.1021/bi0015865 Cottrell, G. S., Padilla, B., Pikios, S., Roosterman, D., Steinhoff, M., Gehringer, D., Grady, E. F. and Bunnett, N. W. (2006) Ubiquitin-dependent down-regulation of the neurokinin-1 receptor. The Journal of Biological Chemistry, 281 (38). pp. 27773-27783. ISSN 1083-351X doi: 10.1074/jbc.M603369200 Cottrell, G. S., Padilla, B., Pikios, S., Roosterman, D., Steinhoff, M., Grady, E. F. and Bunnett, N. W. (2007) Post-endocytic sorting of calcitonin receptor-like receptor and receptor activity-modifying protein 1. The Journal of Biological Chemistry, 282 (16). pp. 12260-12271. ISSN 1083-351X doi: 10.1074/jbc.M606338200 Cottrell, G. S., Roosterman, D., Marvizon, J.-C., Song, B., Wick, E., Pikios, S., Wong, H., Berthelier, C., Tang, Y., Sternini, C., Bunnett, N. W. and Grady, E. F. (2005) Localization of calcitonin receptor-like receptor and receptor activity modifying protein 1 in enteric neurons, dorsal root ganglia, and the spinal cord of the rat. Journal of Comparative Neurology, 490 (3). pp. 239-255. ISSN 1096-9861 doi: 10.1002/cne.20669 Coxon, C. H., Bicknell, K. A., Moseley, F. L. and Brooks, G. (2009) Over expression of Plk1 does not induce cell division in rat cardiac myocytes in vitro. PLoS ONE, 4 (8). e6752. ISSN 1932-6203 doi: 10.1371/journal.pone.0006752 DDallas, M., Boycott, H. E., Atkinson, L., Miller, A., Boyle, J. P., Pearson, H. A. and Peers, C. (2007) Hypoxia suppresses glutamate transport in astrocytes. The Journal of Neuroscience, 27 (15). pp. 3946-55. ISSN 1529-2401 Dallas, M., Deuchars, S. A. and Deuchars, J. (2005) Immunopharmacology - antibodies for specific modulation of proteins involved in neuronal function. Journal of Neuroscience Methods, 146 (2). pp. 133-48. ISSN 0165-0270 doi: 10.1016/j.jneumeth.2005.04.015 Dallas, M. L., Atkinson, L., Milligan, C. J., Morris, N. P., Lewis, D. I., Deuchars, S. A. and Deuchars, J. (2005) Localization and function of the Kv3.1b subunit in the rat medulla oblongata: focus on the nucleus tractus solitarii. Journal of Physiology, 562 (Pt 3). pp. 655-72. ISSN 0022-3751 Dallas, M. L., Boyle, J. P., Milligan, C. J., Sayer, R., Kerrigan, T. L., McKinstry, C., Lu, P., Mankouri, J., Harris, M., Scragg, J. L., Pearson, H. A. and Peers, C. (2011) Carbon monoxide protects against oxidant-induced apoptosis via inhibition of Kv2.1. FASEB Journal, 25 (5). pp. 1519-1530. ISSN 0892-6638 doi: 10.1096/fj.10-173450 Dallas, M. L., Deuchars, S. A. and Deuchars, J. (2010) Immunopharmacology: utilizing antibodies as ion channel modulators. Expert Review of Clinical Pharmacology, 3 (3). pp. 281-289. ISSN 1751-2433 doi: 10.1586/ecp.10.18 Dallas, M. L., Morris, N. P., Lewis, D. I., Deuchars, S. A. and Deuchars, J. (2008) Voltage-gated potassium currents within the dorsal vagal nucleus: inhibition by BDS toxin. Brain Research, 1189. pp. 51-57. ISSN 0006-8993 doi: 10.1016/j.brainres.2007.10.090 Dallas, M. L., Scragg, J. L. and Peers, C. (2008) Modulation of hTREK-1 by carbon monoxide. Neuroreport, 19 (3). pp. 345-348. ISSN 1473-558X doi: 10.1097/WNR.0b013e3282f51045 Dallas, M. L., Yang, Z., Boyle, J. P., Boycott, H. E., Scragg, J. L., Milligan, C. J., Elies, J., Duke, A., Thireau, J., Reboul, C., Richard, S., Bernus, O., Steele, D. S. and Peers, C. (2012) Carbon monoxide induces cardiac arrhythmia via induction of the late Na+ current. American Journal of Respiratory and Critical Care Medicine, 186 (7). pp. 648-656. ISSN 1535-4970 doi: 10.1164/rccm.201204-0688OC David, W. I. F. and Shankland, K. (2008) Structure determination from powder diffraction data. Acta Crystallographica Section A, 64 (1). pp. 52-64. ISSN 0108-7673 doi: 10.1107/S0108767307064252 David, W.I.F. and Shankland, K. (2008) Structure determination from powder diffraction data. Acta Crystallographica Section A, 64 (1). pp. 52-64. ISSN 0108-7673 doi: 10.1107/S0108767307064252 De Silva, D. J., French, S. J., Cheung, N. Y., Swinson, A. K., Bendotti, C. and Rattray, M. (2005) Rat brain serotonin neurones that express neuronal nitric oxide synthase have increased sensitivity to the substituted amphetamine serotonin toxins 3,4-methylenedioxymethamphetamine and p-chloroamphetamine. Neuroscience, 134 (4). pp. 1363-75. ISSN 0306-4522 doi: 10.1016/j.neuroscience.2005.05.016 Deaville, E., Green, B., Mueller-Harvey, I., Willoughby, I. and Frazier, R. (2007) Hydrolyzable tannin structures influence relative globular and random coil protein binding strengths. Journal of Agricultural and Food Chemistry, 55 (11). pp. 4554-4561. ISSN 0021-8561 doi: 10.1021/jf063770o Deepika, G., Green, R. J., Frazier, R. A. and Charalampopoulos, D. (2009) Effect of growth time on the surface and adhesion properties of Lactobacillus rhamnosus GG. Journal of Applied Microbiology, 107 (4). pp. 1230-1240. ISSN 1364-5072 doi: 10.1111/j.1365-2672.2009.04306.x Dematos, L.L., Williams, A.C., Booth, S.W., Petts, C.R., Taylor, D.J. and Blagden, N. (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549 doi: 10.1002/jps.20924 Deng, J., Lewis, P. A., Greggio, E., Sluch, E., Beilina, A. and Cookson, M. A. (2008) Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase. Proceedings of the National Academy of Sciences, 105 (5). pp. 1499-1504. ISSN 1091-6490 doi: 10.1073/pnas.0709098105 Denicolo, P. M. (2005) Perspectives on the teaching profession or relative appraisal. In: Denicolo, P. M. and Kompf, M. (eds.) Teacher thinking and professional action. Routledge, London, pp. 17-30. ISBN 9780415362238 Denicolo, P.M. (2005) Doctoral degree assessment criteria:towards transparency through exploring teacher thinking. In: Denicolo, P.M. and Kompf, M. (eds.) Connecting policy and practice: challenges for teaching and learning in schools and universities. Routledge, London, pp. 142-150. ISBN 9780415362245 Denicolo, P.M. (2004) Doctoral supervision of colleagues: peeling off the veneer of satisfaction and competence. Studies in Higher Education, 29 (6). pp. 693-707. ISSN 0307-5079 doi: 10.1080/0307507042000287203 Denicolo, P.M. (2006) Postgraduate research students' learning in higher education. In: Ashwin, P. (ed.) Changing higher education the development of learning and teaching. SEDA Series. Routledge, London, pp. 47-57. ISBN 9780415341295 Denicolo, P.M. (2007) The metamorphosis of doctoral education in the UK and Europe: perspectives from a teacher as learner. In: Butcher, J. and McDonald, L. (eds.) Making a difference: challenges for teachers, teaching and teacher education. Sense Publishers, Rotterdam, pp. 235-250. ISBN 9789087901318 Denicolo, P.M. (2005) A range of elicitation methods to suit client and purpose. In: Fransella, F. (ed.) The essential practitioner's handbook of personal construct psychology. John Wiley & Sons Ltd, Chichester, pp. 57-66. ISBN 9780470013236 Denicolo, P.M. and Becker, L.M. (2008) The supervision process and the nature of the research degree. In: Hall, G. and Longman, J. (eds.) The postgraduate’s companion. Sage, London. ISBN 9781412930253 Denicolo, P.M. and Kompf, M., eds. (2005) Connecting policy and practice: challenges for teaching and learning in schools and universities. Routledge, London. ISBN 9780415362245 Denicolo, P.M. and Kompf, M., eds. (2005) Teacher thinking and professional action. Routledge, London. ISBN 9780415362238 Dennis, I., Whalley, B. J. and Stephens, G. J. (2008) Effects of Delta9-tetrahydrocannabivarin on [35S]GTPgammaS binding in mouse brain cerebellum and piriform cortex membranes. British Journal of Pharmacology, 154 (6). pp. 1349-58. ISSN 0007-1188 doi: 10.1038/bjp.2008.190 Dennis, S., Jaafari, N., Cimarosti, H., Hanley, J. G., Henley, J. M. and Mellor, J. R. (2011) Oxygen/Glucose deprivation induces a reduction in synaptic AMPA receptors on hippocampal CA3 neurons mediated by mGluR1 and adenosine A3 receptors. The Journal of Neuroscience, 31 (33). pp. 11941-11952. ISSN 1529-2401 doi: 10.1523/JNEUROSCI.1183-11.2011 Devine, M. J., Kaganovich, A., Ryten, M., Mamais, A., Trabzuni, D., Manzoni, C., McGoldrick, P., Chan, D., Dillman, A., Zerle, J., Horan, S., Taanman, J.-W., Hardy, J., Marti-Masso, J.-F., Healy, D., Schapira, A. H., Wolozin, B., Bandopadhyay, R., Cookson, M. R., van der Brug, M. P. and Lewis, P. A. (2011) Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue. PLoS ONE, 6 (7). e22489. ISSN 1932-6203 doi: 10.1371/journal.pone.0022489 Di Petta, T., ed. (2008) The emperor’s new computer: ICT, teachers and teaching. Critical issues in the future of learning and teaching, 2. Sense Publishers, Rotterdam. ISBN 9789087906559 Dolman, D., Drndarski, S., Abbott, N. J. and Rattray, M. (2005) Induction of aquaporin 1 but not aquaporin 4 messenger RNA in rat primary brain microvessel endothelial cells in culture. Journal of Neurochemistry, 93 (4). pp. 825-33. ISSN 1471-4159 doi: 10.1111/j.1471-4159.2005.03111.x Donyai, P. (2009) Information retrieval. In: Smith, I. , Winfield, A.J. and Rees, J. (eds.) Pharmaceutical practice. Churchill Livingstone, New York, pp. 235-260. ISBN 9780443069062 Donyai, P. (2010) Quality of medicines stored together in multi-compartment compliance aids. Journal of Clinical Pharmacy and Therapeutics, 35 (5). pp. 533-543. ISSN 1365-2710 doi: 10.1111/j.1365-2710.2009.01129.x Donyai, P. (2012) Social and cognitive pharmacy: theory and case studies. Pharmaceutical Press, London, pp. 1-248. ISBN 9780853698999 Donyai, P., Alexander, A. and Denicolo, P. (2013) A framework for assessing continuing professional development activities for satisfying pharmacy revalidation requirements. Journal of Continuing Education in the Health Professions. ISSN 1554-558X (In Press) Donyai, P. and Bateman, R. (2007) Errors associated with preparation of adult and paediatric parenteral nutrition in UK hospital pharmacies. In: The European Society for Clinical Nutrition and Metabolism, 2007, September 8-11, Prague, Czech Republic. (Unpublished) Donyai, P. and Denicolo, P. (2009) Understanding and dealing with stress and pressure in the workplace. The Pharmaceutical Journal, 282. pp. 643-645. Donyai, P. and Hasan, S. I. (2009) The imminent availability of a potent weight-loss medicine in pharmacies: public perception of effectiveness. In: The British Psychological Society Annual Conference, 2009, April 1-3, Brighton, UK. (Unpublished) Donyai, P. and Van den Berg, M. (2009) Coronary heart disease risk screening: the community pharmacy Healthy Heart Assessment Service. Pharmacy World & Science, 31 (6). pp. 643-647. ISSN 0928-1231 doi: 10.1007/s11096-009-9338-4 Donyai, P., Alexander, A. and Denicolo, P. (2010) CPD records for revalidation: assessing fitness-to-practise using ‘revalidation standards’ and an Outcomes Framework. Project Report. The General Pharmaceutical Council, London. pp245. Donyai, P., Denicolo, P. M., Herbert, R. Z. and Alexander, A. M. (2010) Methodology for assessing the appropriateness of Continuing Professional Development for pharmacy professionals’ revalidation. International Journal of Pharmacy Practice, 18 (S1). p. 11. ISSN 0961-7671 doi: DOI:10.1111/j.2042-7174.2010.00007.x Donyai, P., Denicolo, P. and Alexander, A. (2011) Continuing Professional Development for pharmacy professionals’ revalidation: results of an experimental study. International Journal of Pharmacy Practice, 19 (S1). p. 37. ISSN 0961-7671 Donyai, P., Herbert, R. Z., Denicolo, P. M. and Alexander, A. M. (2011) British pharmacy professionals' beliefs and participation in continuing professional development: a review of the literature. International Journal of Pharmacy Practice, 19 (5). pp. 290-317. ISSN 0961-7671 doi: 10.1111/j.2042-7174.2011.00128.x Donyai, P., Herbert, R. Z., Denicolo, P. M. and Alexander, A. M. (2011) British pharmacy professionals’ beliefs and participation in continuing professional development: a review of the literature. International Journal of Pharmacy Practice, 19 (5). pp. 290-317. ISSN 2042-7174 doi: 10.1111/j.2042-7174.2011.00128.x Donyai, P., O'Grady, K., Jacklin, A., Barber, N. and Franklin, B. D. (2008) The effects of electronic prescribing on the quality of prescribing. British Journal of Clinical Pharmacology, 65 (2). pp. 230-237. ISSN 0306-5251 doi: 10.1111/j.1365-2125.2007.02995.x. Dora, K. A., Gallagher, N. T., McNeish, A. and Garland, C. J. (2008) Modulation of endothelial cell KCa3.1 Channels during endothelium-derived hyperpolarizing factor signaling in mesenteric resistance arteries. Circulation Research, 102 (10). pp. 1427-1255. ISSN 0009-7330 doi: 10.1161/CIRCRESAHA.108.172379 Dove, B., Brooks, G., Bicknell, K. A., Wurm, T. and Hiscox, J. A. (2006) Cell cycle perturbations induced by infection with the coronavirus infectious bronchitis virus and their effect on virus replication. Journal of Virology, 80 (8). pp. 4147-4156. ISSN 0022-538X doi: 10.1128/jvi.80.8.4147-4156.2006 Dove, B.K., Bicknell, K., Brooks, G., Harrison, S. and Hiscox, J.A. (2006) Infectious bronchitis coronavirus induces cell-cycle perturbations. In: Perlman, S. and Holmes, K.V. (eds.) Nidoviruses: toward control of SARS and other nidovirus diseases. Advances in Experimental Medicine and Biology, 581. Springer-Verlag, Berlin, pp. 357-362. ISBN 9780387262024 Dove, B.K., You, J.H., Reed, M.L., Emmett, S.R., Brooks, G. and Hiscox, J.A. (2006) Changes in nucleolar morphology and proteins during infection with the coronavirus infectious bronchitis virus. Cellular Microbiology, 8 (7). pp. 1147-1157. ISSN 1462-5814 doi: 10.1111/j.1462-5822.2006.00698.x Dowling, C.M. , Claffrey, J., Cuffe, S., Fichtner, I., Pampillon, C., Sweeney, N.J., Strohfeldt, K., Watson, R., William, G. and Tacke, M. (2008) Antitumor activity of Titanocene Y in xenografted PC3 tumors in mice. Letters in Drug Design & Discovery, 5 (2). pp. 141-144. ISSN 1570-1808 doi: 10.2174/157018008783928463 Dubolazov, A.V., Nurkeeva, Z.S., Mun, G.A. and Khutoryanskiy, V.V. (2006) Design of mucoadhesive polymeric films based on blends of poly(acrylic acid) and (hydroxypropyl)cellulose. Biomacromolecules, 7 (5). pp. 1637-1643. ISSN 1525-7797 doi: 10.1021/bm060090l Dulon, S., Leduc, D., Cottrell, G. S., D'Alayer, J., Hansen, K. K., Bunnett, N. W., Hollenberg, M. D., Pidard, D. and Chignard, M. (2005) Pseudomonas aeruginosa elastase disables proteinase-activated receptor 2 in respiratory epithelial cells. American Journal of Respiratory Cell and Molecular Biology, 32 (5). pp. 411-419. ISSN 1044-1549 doi: 10.1165/rcmb.2004-0274OC Duncan, R., Vicent, M. J., Greco, F. and Nicholson, R. (2005) Polymer-drug conjugates: towards a novel approach for the treatment of endrocine-related cancer. Endocrine related cancer, 12. S189-S199. ISSN 1479-6821 doi: 10.1677/erc.1.01045 ECambridge Enterprise Ltd (2011) Immunoassays, methods for carrying out immunoassays, immunoassay kits and method for manufacturing immunoassay kits. WO/2011/117579. doi: WO/2011/117579 Cambridge Enterprise Ltd (2010) Formulations of viable cells for oral delivery. WO2010079343. doi: WO2010079343 Edwards, A. D., Chatterjee, P., Mahbubani, K. T., Reis, C. M. and Slater, N. K.H. (2010) Optimal protection of stabilised dry live bacteria from bile toxicity in oral dosage forms by bile acid adsorbent resins. Chemical Engineering Science, 65 (16). pp. 4844-4854. ISSN 0009-2509 doi: 10.1016/j.ces.2010.05.030 Edwards, A. D. and Slater, N. K.H. (2008) Formulation of a live bacterial vaccine for stable room temperature storage results in loss of acid, bile and bile salt resistance. Vaccine, 26 (45). pp. 5675-5678. ISSN 0264-410X doi: 10.1016/j.vaccine.2008.08.024 Edwards, A. D. and Slater, N. K.H. (2009) Protection of live bacteria from bile acid toxicity using bile acid adsorbing resins. Vaccine, 27 (29). pp. 3897-3903. ISSN 0264-410X doi: 10.1016/j.vaccine.2009.04.006 Edwards, A. D., Reis, N. M., Slater, N. K. H. and Mackley, M. R. (2011) A simple device for multiplex ELISA made from melt-extruded plastic microcapillary film. Lab on a Chip (11). pp. 4267-4273. ISSN 1473-0197 doi: 10.1039/C0LC00357C Edwards, A.D. (2013) What have dendritic cells ever done for adjuvant design? Cellular and molecular methods for the rational development of vaccine adjuvants. In: Flower , D. R. and Perrie, Y. (eds.) Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines. Immunomics reviews (5). Springer, New York , pp. 131-154. ISBN 978-1-4614-5070-2 doi: 10.1007/978-1-4614-5070-2_8 Edwards, I. J., Dallas, M. L., Poole, S. L., Milligan, C. J., Yanagawa, Y., Szabó, G., Erdélyi, F., Deuchars, S. A. and Deuchars, J. (2007) The neurochemically diverse intermedius nucleus of the medulla as a source of excitatory and inhibitory synaptic input to the nucleus tractus solitarii. The Journal of Neuroscience, 27 (31). pp. 8324-8333. ISSN 1529-2401 doi: 10.1523/JNEUROSCI.0638-07.2007 El Maghraby, G. M. and Williams, A. C. (2009) Vesicular systems for delivering conventional small organic molecules and larger macromolecules to and through human skin. Expert Opinion on Drug Delivery, 6 (2). pp. 149-163. ISSN 1742-5247 doi: 10.1517/17425240802691059 El Maghraby, G. M. M., Williams, A. C. and Barry, B. W. . (2004) Interactions of surfactants (edge activators) and skin penetration enhancers with liposomes. International Journal of Pharmaceutics, 276 (1-2). pp. 143-161. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2004.02.024 El Maghraby, G.M.M., Williams, A.C. and Barry, B.W. (2006) Can drug-bearing liposomes penetrate intact skin? Journal of Pharmacy and Pharmacology, 58 (4). pp. 415-429. ISSN 0022-3573 doi: 10.1211/jpp.58.4.0001 El Maghraby, G.M.M., Williams, A.C. and Barry, B.W. (2005) Drug interaction and location in liposomes: correlation with polar surface areas. International Journal of Pharmaceutics, 292 (1-2). pp. 179-185. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2004.11.037 Ellis, D., Norman, S. E. and Osborn, H. M. I. (2008) Synthesis of S-linked carbohydrate analogues via a Ferrier reaction. Tetrahedron, 64 (12). pp. 2832-2854. ISSN 0040-4020 doi: 10.1016/j.tet.2008.01.042 Elsabagh, S., Hartley, D.E., Ali, O., Williamson, E.M. and File, S.E. (2005) Differential cognitive effects of Ginkgo biloba after acute and chronic treatment in healthy young volunteers. Psychopharmacology, 179 (2). pp. 437-446. ISSN 0033-3158 doi: 10.1007/s00213-005-2206-6 Emmott, E., Dove, B. K., Howell, G., Chappell, L. A., Reed, M. L., Boyne, J. R., You, J. H., Brooks, G., Whitehouse, A. and Hiscox, J. A. (2008) Viral nucleolar localisation signals determine dynamic trafficking within the nucleolus. Virology, 380 (2). pp. 191-202. ISSN 1096-0341 doi: 10.1016/j.virol.2008.05.032 Espallargas, G. M., Zordan, F., Marin, L. A., Adams, H., Shankland, K., van de Streek, J. and Brammer, L. (2009) Rational modification of the hierarchy of intermolecular interactions in molecular crystal structures by using tunable halogen bonds. Chemistry - A European Journal, 15 (31). pp. 7554-7568. ISSN 0947-6539 doi: 10.1002/chem.200900410 FFante, C., Eldar-Boock, A., Satchi-Fainaro, R., Osborn, H. M. I. and Greco, F. (2011) Synthesis and biological evaluation of a polyglutamic acid-dopamine conjugate: a new antiangiogenic agent. Journal of Medicinal Chemistry, 54 (14). pp. 5255-5259. ISSN 0022-2623 doi: 10.1021/jm200382r Farrar, V. and Young, R. (2007) Supervising disabled research students. Issues in postgraduate education: management, teaching and supervision, 3. Society for Research into Higher Education , London. ISBN 9780946376100 Farrimond, J. A., Mercier, M. S., Whalley, B. J. and Williams, C. M. (2011) Cannabis sativa and the endogenous cannabinoid system: therapeutic potential for appetite regulation. Phytotherapy Research, 25 (2). pp. 170-188. ISSN 0951-418X Farrimond, J. A., Whalley, B. J. and Williams, C. M. (2012) Cannabinol and cannabidiol exert opposing effects on rat feeding patterns. Psychopharmacology, 223 (1). pp. 117-129. ISSN 0033-3158 doi: 10.1007/s00213-012-2697-x Farrimond, J. A., Whalley, B. and Williams, C. (2012) Non-D9-tetrahydrocannabinol phytocannabinoids stimulate feeding in rats. Behavioural Pharmacology, 23 (1). pp. 113-117. ISSN 0955-8810 doi: 10.1097/FBP.0b013e32834ed832 Farrimond, J., Hill, A. J., Jones, N., Stephens, G. J., Whalley, B. J. and Williams, C. M. (2009) A cost-effective high-throughput digital system for observation and acquisition of animal behavioral data. Behavior Research Methods, 41 (2). pp. 446-451. ISSN 1554-351X doi: 10.3758/BRM.41.2.446 Farrimond, J., Whalley, B. J. and Williams, C. M. (2010) A low delta-9-tetrahydrocannabinol cannabis extract induces hyperphagia in rats. Behavioural Pharmacology, 21 (8). pp. 769-772. ISSN 0955-8810 doi: 10.1097/FBP.0b013e328340a062 Farrimond, J., Whalley, B. J. and Williams, C. M. (2010) Cannabis constituents modulate ∆9-tetrahydrocannabinol-induced hyperphagia in rats. Psychopharmacology, 210 (1). pp. 97-106. ISSN 0033-3158 doi: 10.1007/s00213-010-1821-z Fefelova, N.A., Nurkeeva, Z.S., Mun, G.A. and Khutoryanskiy, V.V. (2007) Mucoadhesive interactions of amphiphilic cationic copolymers based on [2-(methacryloyloxy)ethyl]trimethylammonium chloride. International Journal of Pharmaceutics, 339 (1-2). pp. 25-32. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2007.02.019 Feng, Y., Foster, J., Mi, S., Chen, B. and Connon, C. (2012) Influence of substrate on corneal epithelial cell viability within ocular surface models. Experimental Eye Research, 101. pp. 97-103. ISSN 0014-4835 doi: 10.1016/j.exer.2012.05.005 Fern, S. E., Heath, P. and Cobb, A. J. A. (2011) Aldol reaction of butane-2,3-diacetal protected methyl glycerate. Tetrahedron: Asymmetry, 22 (2). pp. 149-152. ISSN 0957-4166 doi: 10.1016/j.tetasy.2011.01.004 Fernandes, P., Bardin, J., Johnston, A., Florence, A. J., Leech, C. K., David, W. I. F. and Shankland, K. (2007) Carbamazepine trifluoroacetic acid solvate. Acta Crystallographica Section E: Structure Reports Online, 63 (11). o4269. ISSN 1600-5368 doi: 10.1107/S1600536807045333 Fernandes, P., Florence, A. J., Fabbiani, F., David, W. I. F. and Shankland, K. (2008) Urea-N,N-dimethylacetamide (1/1). Acta Crystallographica Section E: Structure Reports Online, 64 (2). o355. ISSN 1600-5368 doi: 10.1107/S1600536807067232 Fernandes, P., Shankland, K., David, W.I.F., Markvardsen, A.J., Florence, A.J., Shankland, N. and Leech, C.K. (2008) A differential thermal expansion approach to crystal structure determination from powder diffraction data. Journal of Applied Crystallography , 41 (6). pp. 1089-1094. ISSN 0021-8898 doi: 10.1107/S0021889808030872 Fichtner, I., Pampillon, C., Sweeney, N.J., Strohfeldt, K. and Tacke, M. (2006) Anti-tumor activity of Titanocene Y in xenografted Caki-1 tumors in mice. Anti-Cancer Drugs, 17 (3). pp. 333-336. ISSN 0959-4973 File, S. E., Hartley, D. E., Alom, N. and Rattray, M. (2003) Soya phytoestrogens change cortical and hippocampal expression of BDNF mRNA in male rats. Neuroscience Letters, 338 (2). pp. 135-138. ISSN 0304-3940 doi: 10.1016/S0304-3940(02)01391-5 Florence, A.J., Bedford, C.T., Fabbiani, F.P.A., Shankland, K., Gelbrich, T., Hursthouse, M.B., Shankland, N., Johnston, A. and Fernandes, P. (2008) Two-dimensional similarity between forms I and II of cytenamide, a carbamazepine analogue. Crystengcomm, 10 (7). pp. 811-813. ISSN 1466-8033 doi: 10.1039/b719717a Florence, A.J., Shankland, K., Gelbrich, T., Hursthouse, M.B., Shankland, N., Johnston, A., Fernandes, P. and Leech, C.K. (2008) A catemer-to-dimer structural transformation in cyheptamide. Crystengcomm, 10 (1). pp. 26-28. ISSN 1466-8033 doi: 10.1039/b712547j Franklin, B. D., O'Grady, K., Donyai, P., Jacklin, A. and Barber, N. (2007) The impact of a closed-loop electronic prescribing and automated dispensing system on the ward pharmacist’s time and activities. International Journal of Pharmacy Practice, 15 (2). pp. 133-139. ISSN 0961-7671 doi: 10.1211/ijpp.15.2.0009 Frazier, R. A., Deaville, E. R., Green, R. J., Stringano, E., Willoughby, I., Plant, J. and Mueller-Harvey, I. (2010) Interactions of tea tannins and condensed tannins with proteins. Journal of Pharmaceutical and Biomedical Analysis , 51 (2). pp. 490-495. ISSN 0731-7085 doi: 10.1016/j.jpba.2009.05.035 Frazier, R. A., Papadopoulou, A., Mueller-Harvey, I., Kissoon, D. and Green, R. J. (2003) Probing protein−tannin interactions by isothermal titration microcalorimetry. Journal of Agricultural and Food Chemistry, 51 (18). pp. 5189-5195. ISSN 0021-8561 doi: 10.1021/jf021179v Frazier, R., Papadopoulou, A. and Green, R. (2006) Isothermal titration calorimetry study of epicatechin binding to serum albumin. Journal of Pharmaceutical and Biomedical Analysis , 41 (5). pp. 1602-1605. ISSN 0731-7085 doi: 10.1016/j.jpba.2006.02.004 GGaynor, J. W., Brazier, J. and Cosstick, R. (2007) Synthesis of 3 '-S-phosphorothiolate oligonucleotides for their potential use in RNA interference. Nucleosides Nucleotides & Nucleic Acids, 26 (6-7). pp. 709-712. ISSN 1525-7770 doi: 10.1080/15257770701490753 Gazzieri, D., Trevisani, M., Springer, J., Harrison, S., Cottrell, G. S., Andre, E., Nicoletti, P., Massi, D., Zecchi, S., Nosi, D., Santucci, M., Gerard, N. P., Lucattelli, M., Lungarella, G., Fischer, A., Grady, E. F., Bunnett, N. W. and Geppetti, P. (2007) Substance P released by TRPV1-expressing neurons produces reactive oxygen species that mediate ethanol-induced gastric injury. Free Radical Biology and Medicine, 43 (4). pp. 581-589. ISSN 0891-5849 doi: 10.1016/j.freeradbiomed.2007.05.018 George, V.T., Brooks, G. and Humphrey, T.C. (2007) Regulation of cell cycle and stress responses to hydrostatic pressure in fission yeast. Molecular Biology of the Cel, 18 (10). pp. 4168-4179. ISSN 1059-1524 doi: 10.1091/mbc.E06-12-1141 Gerrard, S. E., Baniecki, M. L., Sokal, D. C., Morris, M. K., Urdaneta-Hartmann, S., Krebs, F. C., Wigdahl, B., Abrams, B. F., Hanson, C. V., Slater, N. K.H. and Edwards, A. D. (2012) A nipple shield delivery system for oral drug delivery to breastfeeding infants : Microbicide delivery to inactivate HIV. International Journal of Pharmaceutics, 434 (1-2). 224- 234. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2012.05.035 Goggi, J.L., Sardini, A., Egerton, A., Strange, P.G. and Grasby, P.M. (2007) Agonist-dependent internalization of D2 receptors: Imaging quantification by confocal microscopy. Synapse, 61 (4). pp. 231-41. ISSN 0887-4476 doi: 10.1002/syn.20360 Grant, A. D., Cottrell, G. S., Amadesi, S., Trevisani, M., Nicoletti, P., Materazzi, S., Altier, C., Cenac, N., Zamponi, G. W., Bautista-Cruz, F., Lopez, C. B., Joseph, E. K., Levine, J. D., Liedtke, W., Vanner, S., Vergnolle, N., Geppetti, P. and Bunnett, N. W. (2007) Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice. Journal of Physiology, 578 (3). pp. 715-733. ISSN 0022-3751 doi: 10.1113/jphysiol.2006.121111 Greco, F., Arif, I., Botting , R., Fante, C., Quintieri, L., Clementi, C., Schiavon, O. and Pasut, G. (2013) Polysialic acid as a drug carrier: evaluation of a new polysialic acid–epirubicin conjugate and its comparison against established drug carriers. Polymer Chemistry, 4. pp. 1600-1609. ISSN 1759-9954 doi: 10.1039/C2PY20876H Greco, F., Vicent, M. J., Penning, N. A., Nicholson, R. I. and Duncan, R. (2005) HPMA copolymer-aminoglutethimide conjugates inhibit aromatase in MCF-7 cell lines. Journal of Drug Targeting, 13 (8-9). pp. 459-470. ISSN 1061-186X doi: 10.1080/10611860500383788 Greco, F. and Vicent, M. (2009) Combination therapy: opportunities and challenges for polymer-drug conjugates as anticancer nanomedicines. Advanced Drug Delivery Reviews, 61 (13). pp. 1203-1213. ISSN 0169-409X doi: DOI:10.1016/j.addr.2009.05.006 Greco, F. and Vicent, M. J. (2008) Polymer-drug conjugates: current status and future trends. Frontiers in Bioscience, 13. pp. 2744-2756. ISSN 1093-9946 doi: 10.2741/2882 Greco, F., Vicent, M.J., Gee, S., Jones, A.T., Gee, J., Nicholson, R.I. and Duncan, R. (2007) Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells. Journal of Controlled Release, 117 (1). pp. 28-39. ISSN 0168-3659 doi: 10.1016/j.jconrel.2006.10.012 Greenland, B. W., Bird, M. B., Burattini, S., Cramer, R., O'Reilly, R. K., Patterson, J. P., Hayes, W., Cardin, C. J. and Colquhoun, H. M. (2013) Mutual binding of polymer end-groups by complementary π–π-stacking: a molecular “Roman Handshake”. Chemical Communications (49). pp. 454-456. ISSN 1359-7345 doi: 10.1039/C2CC35965K Griffin, T. A. N., Shankland, K., van de Streek, J. V. and Cole, J. (2009) GDASH: a grid-enabled program for structure solution from powder diffraction data. Journal of Applied Crystallography, 42 (2). pp. 356-359. ISSN 0021-8898 doi: DOI:10.1107/S0021889809006840 Griffin, T. A. N., Shankland, K., van de Streek, J. V. and Cole, J. (2009) MDASH: a multi-core-enabled program for structure solution from powder diffraction data. Journal of Applied Crystallography, 42 (2). pp. 360-361. ISSN 0021-8898 doi: DOI:10.1107/S0021889809006852 Gulfraz, M., Mehmood, S., Ahmad, A., Fatima, N., Praveen, Z. and Williamson, E. M. (2008) Comparison of the antidiabetic activity of Berberis lyceum root extract and berberine in alloxan-induced diabetic rats. Phytotherapy Research, 22 (9). pp. 1208-1212. ISSN 0951-418X doi: 10.1002/ptr.2438 HHall, D. J., Khutoryanskaya, O. V. and Khutoryanskiy, V. V. (2011) Developing synthetic mucosa-mimetic hydrogels to replace animal experimentation in characterisation of mucoadhesive drug delivery systems. Soft Matter, 7 (20). pp. 9620-9623. ISSN 1744-683X doi: 10.1039/C1SM05929G Harper, J.V. and Brooks, G. (2006) The eukaryotic cell cycle. In: Hiscox, J.A. (ed.) Viruses and the nucleus. Wiley, Chichester, pp. 25-68. ISBN 9780470851128 Harper, J.V. and Brooks, G. (2005) The mammalian cell cycle: an overview. In: Humphrey, T. and Brooks, G. (eds.) Cell cycle control: mechanisms and protocols. Methods in molecular biology, 296. Humana Press, New Jersey, pp. 113-153. ISBN 9781588291448 doi: 10.1385/1-59259-857-9:113 Harrison, S.M., Dove, B.K., Rothwell, L., Kaiser, P., Tarpey, I., Brooks, G. and Hiscox, J.A. (2007) Characterisation of cyclin D1 down-regulation in coronavirus infected cells. FEBS Letters, 581 (7). pp. 1275-1286. ISSN 0014-5793 doi: 10.1016/j.febslet.2007.02.039 Harvey, V.L., Duguid, I.C., Krasel, C. and Stephens, G.J. (2006) Evidence that GABA rho subunits contribute to functional ionotropic GABA receptors in mouse cerebellar Purkinje cells. Journal of Physiology-London, 577 (1). pp. 127-139. ISSN 0022-3751 doi: 10.1113/jphysiol.2006.112482 Hasdemir, B., Bunnett, N. W. and Cottrell, G. S. (2007) Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) mediates post-endocytic trafficking of protease-activated receptor 2 and calcitonin receptor-like receptor. The Journal of Biological Chemistry, 282 (40). pp. 29646-57. ISSN 1083-351X doi: 10.1074/jbc.M702974200 Haworth, B., Lin, H., Fidock, M., Dorr, P. and Strange, P.G. (2007) Allosteric effects of antagonists on signalling by the chemokine receptor CCR5. Biochemical Pharmacology, 74 (6). pp. 891-897. ISSN 0006-2952 doi: 10.1016/j.bcp.2007.06.032 Hayat, S., Williams, R.J. and Rattray, M. (2006) Serotonin transporter expression is not sufficient to confer cytotoxicity to 3,4-methylenedioxymethamphetamine (MDMA) in vitro. Journal of Psychopharmacology, 20 (2). pp. 257-263. ISSN 1461-7285 doi: 10.1177/0269881106063273 Heinrich, M., Barnes, J., Gibbons, S. and Williamson, E. M. (2012) Fundamentals of pharmacognosy and phytotherapy. 2nd edition. Elsevier, Edinburgh, pp326. ISBN 9780702033889 Hettiarachchi, N. T., Boyle, J. P., Bauer, C. C., Dallas, M. L., Pearson, H. A., Hara, S., Gamper, N. and Peers, C. (2012) Peroxynitrite mediates disruption of Ca2+ homeostasis by carbon monoxide via Ca2+ ATPase degradation. Antioxidants & Redox Signaling, 17 (5). pp. 744-755. ISSN 1523-0864 Hettiarachchi, N. T., Dallas, M. L., Pearson, H. A., Bruce, G., Deuchars, S., Boyle, J. P. and Peers, C. (2010) Gap junction-mediated spontaneous Ca(2+) waves in differentiated cholinergic SN56 cells. Biochemical and Biophysical Research Communications, 397 (3). pp. 564-568. ISSN 0006-291X doi: 10.1016/j.bbrc.2010.05.159 Hettiarachchi, N. T., Parker, A., Dallas, M. L., Pennington, K., Hung, C.-C., Pearson, H. A., Boyle, J. P., Robinson, P. and Peers, C. (2009) Alpha-synuclein modulation of Ca2+ signaling in human neuroblastoma (SH-SY5Y) cells. Journal of Neurochemistry, 111 (5). pp. 1192-1201. ISSN 0022-3042 doi: 10.1111/j.1471-4159.2009.06411.x Hill, A. J., Mercier, M. S., Hill, T. D., Glyn, S. E., Jones, N. A., Yamasaki, Y., Futamura, T., Duncan, M., Stott, C.G., Stephens, G.J., Williams, C. M. and Whalley, B.J. (2012) Cannabidivarin is anticonvulsant in mouse and rat in vitro and in seizure models. British Journal of Pharmacology, 167 (8). pp. 1629-1642. ISSN 0007-1188 doi: 10.1111/j.1476-5381.2012.02207.x Hill, A. J., Williams, C. M., Whalley, B. J. and Stephens, G. J. (2012) Phytocannabinoids as novel therapeutic agents in CNS disorders. Pharmacology & Therapeutics, 133 (1). pp. 79-97. ISSN 0163-7258 doi: 10.1016/j.pharmthera.2011.09.002 Hill, A. J., Jones, N., Williams, C. M., Stephens, G. J. and Whalley, B. J. (2010) Development of multi-electrode array screening for anticonvulsants in acute rat brain slices. Journal of Neuroscience Methods, 185 (2). 246 -256 . ISSN 0165-0270 doi: 10.1016/j.jneumeth.2009.10.007 Hill, A. J., Weston, S. E., Jones, N., Smith, I., Bevan , S., Williamson, E. M., Stephens, G. J., Williams, C. M. and Whalley, B. J. (2010) Δ9-tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rat. Epilepsia, 51 (8). pp. 1522-1532. ISSN 0013-9580 doi: 10.1111/j.1528-1167.2010.02523.x Hill, A.J., Zwart, I., Samaranayake, A.N., Al-Allaf, F., Girdlestone, J., Mehmet, H., Navarrete, R., Navarrete, C. and Jen, L.S. (2009) Rat neurosphere cells protect axotomized rat retinal ganglion cells and facilitate their regeneration. Journal of Neurotrauma, 26 (7). pp. 1147-1156. ISSN 0897-7151 doi: 10.1089/neu.2008.0801 Hoffmann, C., Ziegler, N., Reiner, S., Krasel, C. and Lohse, M.J. (2008) Agonist-selective, receptor-specific interaction of human P-2Y receptors with beta-arrestin-1 and-2. The Journal of Biological Chemistry, 283 (45). pp. 30933-30941. ISSN 1083-351X doi: 10.1074/jbc.M801472200 Hooper, C. L., Dash, P. R. and Boateng, S. Y. (2012) Lipoma preferred partner is a mechanosensitive protein regulated by nitric oxide in the heart. FEBS Open Bio, 2. pp. 135-144. ISSN 2211-5463 doi: 10.1016/j.fob.2012.05.005 (In Press) Howard, R. and Howard, P. (2012) GP guide to drugs used in palliative care: psychostimulants. Prescriber, 23 (21). pp. 47-51. ISSN 0959-6682 doi: 10.1002/psb.984 Howard, R. and Howard, P. (2012) What GPs need to know about palliative-care drugs : methadone. Prescriber, 23 (18). pp. 34-38. ISSN 0959-6682 doi: 10.1002/psb.959 Howard, R. L. (2008) A qualitative exploration of the underlying causes of preventable drug-related morbidity in primary care, resulting in hospitalisation. Report. Pharmacy Practice Research Trust , London. pp61. ISBN 9780955696947 Howard, R. L. and Avery, A. J. (2009) Medicines management. In: Hurwitz, B. and Sheikh, A. (eds.) Health care errors and patient safety. Blackwell, Oxford, pp. 150-165. ISBN 9781405146432 Howard, R. L. and Howard, P. D. (2012) What GPs need to know about palliative-care drugs: ketamine. Prescriber, 23 (12). pp. 43-46. ISSN 0959-6682 doi: 10.1002/psb.933 Howard, R. L., Avery, A. J. and Morris, C. J. (2006) Using chart review and clinical databases to study medical error. In: Walshe, K. and Boaden, R. (eds.) Patient safety: research into practice. Open University Press, Maidenhead, pp. 118-129. ISBN 9780335218530 Howard, R., Avery, A. and Bissell, P. (2008) Causes of preventable drug-related hospital admissions: a qualitative study. Quality & Safety in Health Care, 17 (2). pp. 109-116. ISSN 1475-3898 doi: 10.1136/qshc.2007.022681 Howard, R., Avery, A.J., Howard, P. and Partridge, M. (2003) Investigation into the reasons for preventable drug related admissions to a medical admissions unit: observational study. Quality & Safety in Health Care, 12 (4). pp. 280-285. ISSN 2044-5423 doi: 10.1136/qhc.12.4.280 Howard, R.L. (2006) Beta-blocker selectivity and airways obstruction. Prescriber, 17 (22). pp. 52-55. ISSN 0959-6682 Howard, R.L. (2006) NSAIDs: GI risk with a past history of peptic ulceration. Prescriber, 17 (24). pp. 29-31. ISSN 0959-6682 Howard, R.L. and Avery, A.J. (2006) Pharmacist-led medication reviews can reduce patient morbidity? Age and Ageing, 35 (6). pp. 555-556. ISSN 0002-0729 doi: 10.1093/ageing/afl110 Howard, R.L., Avery, A.J. and Bissell, P. (2006) Description of a multifaceted strategy for recruiting general practitioners and community pharmacists to talk about medication errors. International Journal of Pharmacy Practice, 14 (3). pp. 205-209. ISSN 2042-7174 doi: 10.1211/ijpp.14.3.0007 Howard, R.L., Avery, A.J., Slavenburg, S., Royal, S., Pipe, G., Lucassen, P. and Pirmohamed, M. (2007) Which drugs cause preventable admissions to hospital? A systematic review. British Journal of Clinical Pharmacology, 63 (2). pp. 136-147. ISSN 0306-5251 doi: 10.1111/j.1365-2125.2006.02698.x Humphrey, T. and Brooks, G., eds. (2005) Cell cycle control: mechanisms and protocols. Methods in molecular biology, 296. Humana Press, New Jersey, pp402. ISBN 9781588291448 IIkematsu , N., Dallas, M. L., Ross, F. A., Lewis , R. W., Rafferty , J. N., David , J. A., Surman, R., Peers, C., Hardie, D. G. and Evans, A. M. (2011) Phosphorylation of the voltage-gated potassium channel Kv2.1 by AMP-activated protein kinase regulates membrane excitability. Proceedings of the National Academy of Sciences of the United States of America, 108 (44). pp. 18132-18137. ISSN 0027-8424 doi: 10.1073/pnas.1106201108 Irmukhametova, G. S., Mun, G. A. and Khutoryanskiy, V. V. (2011) Thiolated mucoadhesive and PEGylated nonmucoadhesive organosilica nanoparticles from 3-Mercaptopropyltrimethoxysilane. Langmuir, 27 (15). pp. 9551-9556. ISSN 1520-5827 doi: 10.1021/la201385h Irmukhametova, G., Fraser, B., Keddie, J., Mun, G. and Khutoryanskiy, V. V. (2012) Hydrogen-bonding-driven self-assembly of PEGylated organosilica nanoparticles with poly(acrylic acid) in aqueous solutions and in layer-by-layer deposition at solid surfaces. Langmuir, 28 (1). pp. 299-306. ISSN 0743-7463 doi: 10.1021/la2038735 JJackson, C. and Tinkler, P. (2007) A guide for internal and external PhD examiners. Issues in postgraduate education: management, teaching and supervision, 2. Society for Research into Higher Education , London. ISBN 97809463760904 Jacob, C., Cottrell, G. S., Gehringer, D., Schmidlin, F., Grady, E. F. and Bunnett, N. W. (2005) c-Cbl mediates ubiquitination, degradation, and down-regulation of human protease-activated receptor 2. The Journal of Biological Chemistry, 280 (16). pp. 76-87. ISSN 1083-351X doi: 10.1074/jbc.M500109200 Jacob, C., Yang, P.-C., Darmoul, D., Amadesi, S., Saito, T., Cottrell, G. S., Coelho, A.-M., Singh, P., Grady, E. F., Perdue, M. and Bunnett, N. W. (2005) Mast cell tryptase controls paracellular permeability of the intestine: role of protease-activated receptor 2 and beta-arrestins. Journal of Biological Chemistry, 280 (31). pp. 936-948. ISSN 1083-351X doi: 10.1074/jbc.M506338200 Jacob, R.J. and Cramer, R. (2006) PIGOK: linking protein identity to gene ontology and function. Journal of Proteome Research, 5 (12). pp. 3429-3432. ISSN 1535-3893 doi: 10.1021/pr0601537 Janbon, S., Davey, R.J. and Shankland, K. (2008) The crystal structure of a metastable polymorph of para-azoxyanisole. Crystengcomm, 10 (3). pp. 279-282. ISSN 1466-8033 doi: 10.1039/b715934j Janka, L., Clemente, J., Vaiana, N., Sparatore, A., Romeo, S. and Dunn, B.M. (2008) Targeting the plasmepsin 4 orthologs of Plasmodium sp with "Double Drug" inhibitors. Protein and Peptide Letters, 15 (9). pp. 868-873. ISSN 0929-8665 doi: 10.2174/092986608785849218 Jarvis, A. N., McClaren, A. B., Osborn, H. M. I. and Sweeney, J. (2013) Preparation and ring-opening reactions of N-diphenylphosphinyl vinyl aziridines. Beilstein Journal of Organic Chemistry, 9. pp. 852-859. ISSN 1860-5397 doi: 10.3762/bjoc.9.98 Jawaid, S., Khan, T. H., Osborn, H. M. I. and Williams, N. O. A. (2009) Tyrosinase activated melanoma prodrugs. Anti-cancer agents in medicinal chemistry, 9 (7). pp. 717-727. ISSN 1871-5206 Jawaid, S., Osborn, H.M.I. and Williams, N.A.O. (2007) Fighting skin cancer with prodrugs. Education in Chemistry, 44 (3). pp. 77-81. ISSN 0013-1350 Jebelli, J. D., Dihanich, S., Civiero, L., Manzoni, C., Greggio, E. and Lewis, P. A. (2012) GTP binding and intramolecular regulation by the ROC domain of Death Associated Protein Kinase 1. Scientific Reports, 2. 695. ISSN 2045-2322 doi: 10.1038/srep00695 Johnston, A., Florence, A. J., Fabbiani, F. J. A., Shankland, K. and Bedford, C. T. (2008) Cytenamide-1,4-dioxane (2/1). Acta Crystallographica Section E: Structure Reports Online, 64 (7). o1345-o1346. ISSN 1600-5368 doi: 10.1107/S1600536808018709 Johnston, A., Florence, A. J., Fabbiani, F. J. A., Shankland, K. and Bedford, C. T. (2008) Cytenamide-butyric acid (1/1). Acta Crystallographica Section E: Structure Reports Online, 64 (7). o1295-o1296. ISSN 1600-5368 doi: 10.1107/S1600536808018059 Johnston, A., Florence, A. J., Fabianni, F. J. A., Shankland, K. and Bedford, C. T. (2008) Cytenamide acetic acid solvate. Acta Crystallographica Section E: Structure Reports Online, 64 (6). o1175. ISSN 1600-5368 doi: 10.1107/S160053680801550X Johnston, A., Florence, A. J., Fabianni, F. J. A., Shankland, K., Bedford, C. T. and Bardin, J. (2008) Cytenamide trifluoroacetic acid solvate. Acta Crystallographica Section E: Structure Reports Online, 64 (7). o1215-o1216. ISSN 1600-5368 doi: 10.1107/S1600536808016577 Jones, N. A., Glyn, S., Akiyama, S., Hill, T. D.M., Hill, A., Weston, S., Burnett, M. D.A., Yamasaki, Y., Stephens, G., Whalley, B. and Williams, C. (2012) Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures. Seizure, 21 (5). pp. 344-352. ISSN 1059-1311 doi: 10.1016/j.seizure.2012.03.001 Jones, N. A., Hill, A. J., Smith, I., Bevan, S. A., Williams, C. M., Whalley, B. J. and Stephens, G. J. (2010) Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo. Journal of Pharmacology and Experimental Therapeutics, 332 (2). pp. 569-577. ISSN 0022-3565 doi: 10.1124/jpet.109.159145 Jones, R. R., Hamley, I. and Connon, C. (2012) Ex vivo expansion of limbal stem cells is affected by substrate properties. Stem Cell Research, 8 (3). pp. 403-409. ISSN 1876-7753 doi: 10.1016/j.scr.2012.01.001 Jopeace, A.L., Howard, C.B., Murton, B.L., Edwards, A. and Monie, T.P. (2012) Pattern recognition receptors and infectious diseases. In: Insight and control of infectious disease in global scenario. InTech Open. ISBN 9789535103196 KKhan, A., Benboubetra, M., Sayyed, P. Z., Ng, K. W., Fox, S., Beck, G., Benter, I. F. and Akhtar, S. (2004) Sustained polymeric delivery of gene silencing antisense ODNs, siRNA, DNAzymes and ribozymes: in vitro and in vivo studies. Journal of Drug Targeting, 12 (6). pp. 393-404. ISSN 1061-186X doi: 10.1080/10611860400003858 Khutoryanskaya, O., Mayeva, Z., Mun, G. and Khutoryanskiy, V. V. (2008) Designing Temperature-Responsive Biocompatible Copolymers and Hydrogels Based on 2-Hydroxyethyl(meth)acrylates. Biomacromolecules, 9 (12). pp. 3353-3361. ISSN 1525-7797 doi: 10.1021/bm8006242 Khutoryanskaya, O., Potgieter, M. and Khutoryanskiy, V. V. (2010) Multilayered hydrogel coatings covalently-linked to glass surfaces showing a potential to mimic mucosal tissues. Soft Matter, 6. pp. 551-556. ISSN 1744-683X doi: DOI:10.1039/b918007a Khutoryanskaya, O.V., Khutoryanskiy, V.V. and Pethrick, R.A. (2005) Characterisation of blends based on hydroxyethylcellulose and maleic acid-alt-methyl vinyl ether. Macromolecular Chemistry and Physics, 206 (15). pp. 1497-1510. ISSN 1022-1352 doi: 10.1002/macp.200500069 Khutoryanskaya, O.V., Williams, A.C. and Khutoryanskiy, V.V. (2007) pH-mediated interactions between poly(acrylic acid) and methylcellulose in the formation of ultrathin multilayered hydrogels and spherical nanoparticles. Macromolecules, 40 (21). pp. 7707-7713. ISSN 0024-9297 doi: 10.1021/ma071644v Khutoryanskiy, V. V. (2011) Advances in mucoadhesion and mucoadhesive polymers. Macromolecular Bioscience, 11 (6). pp. 748-764. ISSN 1616-5187 doi: 10.1002/mabi.201000388 Khutoryanskiy, V. V. (2011) Application of interpolymer complexation to coat solid and soft surfaces. In: 38th Annual Waterborne Symposium, 28 February - 4 March 2011, New Orleans, USA, pp. 212-218. (In Press) Khutoryanskiy, V. V. and Khutoryanskaya, O. (2009) Design and evaluation of hydrogel films based on polymeric blends. In: Stein, D. (ed.) Handbook of Hydrogels: Properties, Preparation and Applications. Chemical Engineering Methods and Technology. Nova Science Publishers, Inc., Hauppauge NY USA, pp. 521-540. ISBN 9781607417026 Khutoryanskiy, V. V. and Khutoryanskaya, O. (2009) A basic guide to hydrogels. Newsletter of the United Kingdom and Ireland Controlled Release Society , 14. pp. 26-30. Khutoryanskiy, V. and Staikos, G., eds. (2009) Hydrogen-bonded interpolymer complexes. Formation, structure and applications. World Scientific Publishing (UK) Ltd c/o Marston Book Services, Abingdon, UK, pp366. ISBN 9789812707857 Khutoryanskiy, V.V. (2007) Hydrogen-bonded interpolymer complexes as materials for pharmaceutical applications. International Journal of Pharmaceutics, 334 (1-2). pp. 15-26. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2007.01.037 Khutoryanskiy, V.V. (2009) Pharmaceutical applications of interpolymer complexes. In: Khutoryanskiy, V.V. and Staikos, G. (eds.) Hydrogen-bonded interpolymer complexes: formation, structure and applications. World Scientific, Singapore, pp. 235-258. ISBN 9789812707857 Khutoryanskiy, V.V., Dubolazov, A.V. and Mun, G.A. (2009) pH- and ionic strength effects on interpolymer complexation via hydrogen-bonding. In: Khutoryanskiy, V.V. and Staikos, G. (eds.) Hydrogen-bonded interpolymer complexes: formation, structure and applications. World Scientific, Singapore, pp. 1-22. ISBN 9789812707857 Kirkland, J. G., Cottrell, G. S., Bunnett, N. W. and Corvera, C. U. (2007) Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder. American Journal of Physiology Gastrointestinal and Liver Physiology, 293 (1). G335-G346. ISSN 0193-1857 doi: 10.1152/ajpgi.00425.2006 Knaggs, S., Malkin, H., Osborn, H.M.I., Williams, N.A.O. and Yaqoob, P. (2005) New prodrugs derived from 6-aminodopamine and 4-aminophenol as candidates for melanocyte-directed enzyme prodrug therapy (MDEPT). Organic & Biomolecular Chemistry, 3 (21). pp. 4002-4010. ISSN 1477-0520 doi: 10.1039/b506404j Knecht, W., Cottrell, G. S., Amadesi, S., Mohlin, J., Skaregarde, A., Gedda, K., Peterson, A., Chapman, K., Hollenberg, M. D., Vergnolle, N. and Bunnett, N. W. (2007) Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia. The Journal of Biological Chemistry, 282 (36). pp. 26089-26100. ISSN 1083-351X doi: 10.1074/jbc.M703840200 Knight, P.G., Gladwell, R.T. and Lovell, T.M. (2005) The inhibin-activin system and ovarian folliculogenesis in the chicken. In: Dawson, A. and Sharp, P.J. (eds.) Functional avian endocrinology. Narosa Publishing House , New Delhi, pp. 323-340. ISBN 9788173195686 Kolstoe, S. E., Mangione, P. P., Bellotti, V., Taylor, G. W., Tennent, G. A., Deroo, S., Morrison, A. J., Cobb, A. J. A., Coyne, A., McCammon, M. G., Warner, T. D., Mitchell, J., Gill, R., Smith, M. D., Ley, S. V., Robinson, S. P. and Pepys, M. B. (2010) Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Proceedings of the National Academy of Sciences of the United States of America, 107 (47). pp. 20483-20488. ISSN 0027-8424 doi: 10.1073/pnas.1008255107 Krasel, C., Bunemann, M.B., Lorenz, K. and Lohse, M.J. (2005) beta-arrestin binding to the beta(2)-adrenergic receptor requires both receptor phosphorylation and receptor activation. The Journal of Biological Chemistry, 280 (10). pp. 9528-9535. ISSN 1083-351X doi: 10.1074/jbc.M413078200 Krasel, C., Zabel, U., Lorenz, K., Reiner, S., Al-Sabah, S. and Lohse, M. J. (2008) Dual role of the beta(2)-adrenergic receptor C terminus for the binding of beta-arrestin and receptor internalization. The Journal of Biological Chemistry, 283 (46). pp. 31840-31848. ISSN 1083-351X doi: 10.1074/jbc.M806086200 Kroese, W. L. G., Avery, A. J., Savelyich, B. S. P., Brown, N. S., Schers, H., Howard, R., Hippisley-Cox, J. and Horsfield, P. (2005) Assessing the accuracy of a computerized decision support system for digoxin dosing in primary care: an observational study. Journal of Clinical Pharmacy and Therapeutics, 30 (3). pp. 279-283. ISSN 1365-2710 doi: 10.1111/j.1365-2710.2005.00650.x Kudaibergenov, S. E., Nuraje, N. and Khutoryanskiy, V. (2012) Amphoteric nano-, micro-, and macrogels, membranes, and thin films. Soft Matter, 8 (36). pp. 9302-9321. ISSN 1744-683X doi: 10.1039/C2SM25766A LLad, M. D., Ledger, V. M., Briggs, B., Green, R. J. and Frazier, R. A. (2003) Analysis of the SDS−Lysozyme binding isotherm. Langmuir, 19 (12). pp. 5098-5103. ISSN 0743-7463 doi: 10.1021/la0269560 Lad, M.D., Birembaut, F., Frazier, R.A. and Green, R.J. (2005) Protein-lipid interactions at the air/water interface. Physical Chemistry Chemical Physics, 7 (19). pp. 3478-3485. ISSN 1463-9076 doi: 10.1039/b506558p Lad, M.D., Birembaut, F., Matthew, J.M., Frazier, R. and Green, R. J. (2006) The adsorbed conformation of globular proteins at the air/water interface. Physical Chemistry Chemical Physics, 8 (18). pp. 2179-2186. ISSN 1463-9076 doi: 10.1039/b515934b Lambourne, J., Tosi, P., Marsh, J., Bhandari, D., Green, R. , Frazier, R. and Shewry, P. R. (2010) Characterisation of an s-type low molecular weight glutenin subunit of wheat and its proline and glutamine-rich repetitive domain. Journal of Cereal Science, 51 (1). pp. 96-104. ISSN 0733-5210 doi: 10.1016/j.jcs.2009.10.003 Lau, W. M., Heard, C. M. and White, A. W. (2013) Design, synthesis and in vitro degradation of a novel co-drug for the treatment of psoriasis. Pharmaceutics, 5 (2). pp. 232-245. ISSN 1999-4923 Lau, W. M., Ng, K. W., Sakenyte, K. and Charles, M. H. (2012) Distribution of esterase activity in porcine ear skin, and the effects of freezing and heat separation. International Journal of Pharmaceutics, 433 (1-2). pp. 10-15. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2012.04.079 Lau, W. M., Ng, K. W., White, A. W. and Heard, C. M. (2011) Therapeutic and cytotoxic effects of the novel antipsoriasis codrug, naproxyl-dithranol, on HaCaT cells. Molecular Pharmaceutics, 8 (6). pp. 2398-2407. ISSN 1543-8392 doi: 10.1021/mp200327k Lau, W.-M., White, A. W. and Heard, C. M. (2010) Topical delivery of a naproxen-dithranol co-drug: in vitro skin penetration, permeation, and staining. Pharmaceutical Research, 27 (12). pp. 2734-2742. ISSN 0724-8741 doi: 10.1007/s11095-010-0274-8 Lau, W.-M., White, A. W., Donaldson, M. and Heard, C. M. (2008) Hydrolysis of an Ester Co-drug by Porcine Liver Esterase and Homogenised Skin. In: Perspectives in Percutaneous Penetration 11th International Conference, March 25-29, 2008, La Grande-Motte, France. Lau, W.-M., White, A., Donaldson, M. and Heard, C. (2010) Histochemical visualisation of esterase activity in ex vivo porcine ear skin. In: Perspectives in Percutaneous Penetration 12th International Conference, April 7-10, 2010, La Grande-Motte, France. Leach, K., Chariton, S. J. and Strange, P. G. (2007) Analysis of second messenger pathways stimulated by different chemokines acting at the chemokine receptor. Biochemical Pharmacology, 74 (6). pp. 881-890. ISSN 0006-2952 doi: 10.1016/j.bcp.2007.06.019 Leech, C.K., Fabbiani, F.P.A., Shankland, K., David, W.I.F. and Ibberson, R.M. (2008) Accurate molecular structures of chlorothiazide and hydrochlorothiazide by joint refinement against powder neutron and X-ray diffraction data. Acta Crystallographica Section B, 64 (1). pp. 101-107. ISSN 0108-7681 doi: 10.1107/S010876810705687X Leoni, G., Rattray, M. and Butt, A. M. (2009) NG2 cells differentiate into astrocytes in cerebellar slices. Molecular and Cellular Neuroscience, 42 (3). pp. 208-218. ISSN 1044-7431 doi: 10.1016/j.mcn.2009.07.007 Lewis, P. A. and Cookson, M. R. (2012) Gene expression in the Parkinson's disease brain. Brain Research Bulletin, 88 (4). pp. 302-312. ISSN 0361-9230 doi: 10.1016/j.brainresbull.2011.11.016 Li, J.M., Fan, L.M., George, V.T. and Brooks, G. (2007) Nox2 regulates endothelial cell cycle arrest and apoptosis via p21 (cip1) and p53. Free Radical Biology and Medicine, 43 (6). pp. 976-986. ISSN 0891-5849 doi: 10.1016/j.freeradbiomed.2007.06.001 Lin, H., Saisch, S.G.N. and Strange, P.G. (2006) Assays for enhanced activity of low efficacy partial agonists at the D-2 dopamine receptor. British Journal of Pharmacology, 149 (3). pp. 291-299. ISSN 0007-1188 doi: 10.1038/sj.bjp.0706866 Liu, Y., Feizi, T., Carnpanero-Rhodes, M.A., Childs, R.A., Zhang, Y.N., Muiioy, B., Evans, P.G., Osborn, H.M.I., Otto, D., Crocker, P.R. and Chai, W.C. (2007) Neoglycolipid probes prepared via oxime ligation for microarray analysis of oligosaccharide-protein interactions. Chemistry & Biology, 14 (7). pp. 847-859. ISSN 1074-5521 doi: 10.1016/j.chembiol.2007.06.009 Long, P., Mercer, A., Begum, R., Stephens, G. J., Sihra, T. and Jovanovic, J. (2009) Nerve terminal GABAA receptors activate Ca2+/calmodulin-dependent signaling to inhibit voltage-gated Ca2+ influx and glutamate release. The Journal of Biological Chemistry, 284 (13). pp. 8717-8728. ISSN 1083-351X doi: 10.1074/jbc.M805322200 Lovell, T.M., Knight, P.G. and Gladwell, R. (2006) Differential expression of mRNAs encoding co-receptor (betaglycan) and activin type-I preovulatory and prehierarchical follicles of the putative inhibin and type-II receptors in the laying hen ovary. Journal of Endocrinology, 188 (2). pp. 241-249. ISSN 0022-0795 doi: 10.1677/joe.1.06525 Lovell, T.M., Knight, P.G. and Gladwell, R.T. (2005) Variation in pituitary expression of mRNAs encoding the putative inhibin co-receptor (betaglycan) and type-I and type-II activin receptors during the chicken ovulatory cycle. Journal of Endocrinology, 186 (3). pp. 447-455. ISSN 0022-0795 doi: 10.1677/joe.1.06303 Luo, K., Yin, J.B., Khutoryanskaya, O.V. and Khutoryanskiy, V.V. (2008) Mucoadhesive and elastic films based on blends of chitosan and hydroxyethylcellulose. Macromolecular Bioscience, 8 (2). pp. 184-192. ISSN 1616-5187 doi: 10.1002/mabi.200700185 MMa, A., Boulton, M., Zhao, B., Connon, C., Cai, J. and Albon, J. (2007) A role for Notch signaling in human corneal epithelial cell differentiation and proliferation. Investigative Opthalmology & Visual Science, 48 (8). pp. 3576-3585. ISSN 0146-0404 doi: 10.1167/iovs.06-1373 Ma, Y. L., Weston, S. E., Whalley, B. J. and Stephens, G. J. (2008) The phytocannabinoid Delta(9)-tetrahydrocannabivarin modulates inhibitory neurotransmission in the cerebellum. British Journal of Pharmacology, 154 (1). pp. 204-215. ISSN 0007-1188 doi: 10.1038/bjp.2008.57 Ma, Y.-L., Weston, S.E. , Whalley, B.J. and Stephens, G.J. (2008) The phytocannabinoid Δ9-tetrahydrocannabivarin modulates inhibitory neurotransmission in the cerebellum. British Journal of Pharmacology, 154 (1). pp. 204-215. ISSN 0007-1188 doi: 10.1038/bjp.2008.57 Ma, Y.L., Bates, S. and Gurney, A.M. (2006) The effects of paeonol on the electrophysiological properties of cardiac ventricular myocytes. European Journal of Pharmacology, 545 (2-3). pp. 87-92. ISSN 0014-2999 doi: 10.1016/j.ejphar.2006.06.064 Maghraby, G. M., Barry, B. W. and Williams, A. C. (2008) Liposomes and skin: From drug delivery to model membranes. European Journal of Pharmaceutical Sciences, 34 (4-5). pp. 203-222. ISSN 0928-0987 doi: 10.1016/j.ejps.2008.05.002 Majumder, M., Buckton, G., Rawlinson, C. F., Williams, A. C., Spillman, M. J., Pidcok, E. and Shankland, K. (2013) Application of hydrogen-bond propensity calculations to an indomethacin–nicotinamide (1:1) co-crystal. CrystEngComm, 15. pp. 4041-4044. ISSN 1466-8033 doi: 10.1039/c3ce40367j Majumder, M., Buckton, G., Rawlinson-Malone, C., Williams, A., Spillman, M., Shankland, N. and Shankland, K. (2011) A carbamazepine-indomethacin (1:1) cocrystal produced by milling. Crystengcomm, 13 (21). pp. 6327-6328. ISSN 1466-8033 doi: 10.1039/c1ce05650f Malas, S., Postlethwaite, M., Ekonomou, A., Whalley, B., Nishiguchi, S., Wood, H., Meldrum, B., Constanti, A. and Episkopou, V. (2003) Sox1-deficient mice suffer from epilepsy associated with abnormal ventral forebrain development and olfactory cortex hyperexcitability. Neuroscience, 119 (2). pp. 421-432. ISSN 0306-4522 doi: 10.1016/S0306-4522(03)00158-1 Mangazbaeva, R.A., Mun, G.A., Nurkeeva, Z.S. and Khutoryanskiy, V.V. (2006) Interpolymer complexes of hydroxy-propylmethylcellulose with polycarboxylic acids in aqueous solutions. Polymer International, 55 (6). pp. 668-674. ISSN 0959-8103 doi: 10.1002/pi.2012 Mankouri, J., Dallas, M. L., Hughes, M. E., Griffin, S. D. C., Macdonald, A., Peers, C. and Harris, M. (2009) Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistence. Proceedings of the National Academy of Sciences of the United States of America, 106 (37). pp. 15903-15908. ISSN 0027-8424 doi: 10.1073/pnas.0906798106 Mankouri, J., Tedbury, P. R., Gretton, S., Hughes, M. E., Griffin, S. D. C., Dallas, M. L., Green, K. A., Hardie, D. G., Peers, C. and Harris, M. (2010) Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase. Proceedings of the National Academy of Sciences of the United States of America, 107 (25). pp. 11549-11554. ISSN 0027-8424 doi: 10.1073/pnas.0912426107 Markvardsen, A. J., Puphaiboon, K., Arjeneh, M., Shankland, K., Guest, H. L., Griffin, T. A. N., Badham, D. R. and Flannery, D. W. (2010) Jpowder: a Java-based program for the display and examination of powder diffraction data. Journal of Applied Crystallography, 43 (6). pp. 1532-1534. ISSN 1600-5767 doi: 10.1107/S0021889810041543 Markvardsen, A.J., Shankland, K., David, W.I.F., Johnston, J.C., Ibberson, R.M., Tucker, M., Nowell, H. and Griffin, T. (2008) ExtSym: a program to aid space-group determination from powder diffraction data. Journal of Applied Crystallography, 41 (6). pp. 1177-1181. ISSN 0021-8898 doi: 10.1107/S0021889808031087 Marshall, A.J., Rattray, M. and Vaughan, P.F. (2006) Chronic hypoxia in the human neuroblastoma SH-SY5Y causes reduced expression of the putative alpha-secretases, ADAM10 and TACE, without altering their mRNA levels. Brain Research, 1099 (1). pp. 18-24. ISSN 0006-8993 doi: 10.1016/j.brainres.2006.05.008 Martins, D. M. S., Middlemiss, D. S., Pulham, C. R., Wilson, C. C., Weller, M. T., Henry, P. F., Shankland, N., Shankland, K., Marshall, W. G., Ibberson, R. M., Knight, K., Moggach, S., Brunelli, M. and Morrison, C. A. (2009) Temperature- and Pressure-induced Proton Transfer in the 1:1 Adduct Formed between Squaric Acid and 4,4 '-Bipyridine. Journal of the American Chemical Society, 131 (11). pp. 3884-3893. ISSN 0002-7863 doi: DOI:10.1021/ja8082973 Matthews, E.A., Bee, L.A., Stephens, G.J. and Dickenson, A.H. (2007) The Ca(v)2.3 calcium channel antagonist SNX-482 reduces dorsal horn neuronal responses in a rat model of chronic neuropathic pain. European Journal of Neuroscience, 25 (12). pp. 3561-3569. ISSN 0953-816X doi: 10.1111/j.1460-9568.2007.05605.x Mayer, G., Wulffen, B., Huber, C., Brockmann, J., Flicke, B., Neumann, L., Hafenbradl, D., Klebl, B. M., Lohse, M. J., Krasel, C. and Blind, M. (2008) An RNA molecule that specifically inhibits G-protein-coupled receptor kinase 2 in vitro. Rna-a Publication of the Rna Society, 14 (3). pp. 524-534. ISSN 1355-8382 doi: 10.1261/rna.821908 McKoy, G., Bicknell, K. A., Patel, K., Brooks, G. and , (2007) Developmental expression of myostatin in cardiomyocytes and its effect on foetal and neonatal rat cardiomyocyte proliferation. Cardiovascular Research, 74 (2). pp. 304-312. ISSN 0008-6363 doi: 10.1016/j.cardiores.2007.02.023 McMillan , L. E., Brown, J. T., Henley, J. M. and Cimarosti, H. (2011) Profiles of SUMO and ubiquitin conjugation in an Alzheimer's disease model. Neuroscience Letters, 502 (3). pp. 201-208. ISSN 0304-3940 doi: 10.1016/j.neulet.2011.07.045 McNeish, A., Altayo-Jimenez, F., Cottrell, G. and Garland, C. (2012) Statins and selective inhibition of Rho kinase protect small conductance calcium-activated potassium channel function (KCa2.3) in cerebral arteries. PLoS ONE, 7 (10). e46735. ISSN 1932-6203 doi: 10.1371/journal.pone.0046735 McNeish, A., Altayo-Jimenez, F. and Garland, C. J. (2010) Evidence both L-type and non-L-type voltage-dependent calcium channels contribute to cerebral artery vasospasm following loss of NO in the rat. Vascular Pharmacology, 53 (3-4). pp. 151-159. ISSN 1537-1891 doi: 10.1016/j.vph.2010.06.002 McNeish, A. and Garland , C. J. (2007) Thromboxane A2 inhibition of SKCa after NO synthase block in rat middle cerebral artery. British Journal of Pharmacology, 151 (4). pp. 441-449. ISSN 1476-5381 doi: 10.1038/sj.bjp.0707240 McNeish, A., Roux, B. T., Aylett, S.-B. , Massen Van Den Brink, A. and Cottrell, G. S. (2012) Endosomal proteolysis regulates calcitonin gene-related peptide responses in mesenteric arteries. British Journal of Pharmacology, 167 (8). pp. 1679-1690. ISSN 1476-5381 doi: 10.1111/j.1476-5381.2012.02129.x McNeish, A., Sandow, S.L., Neylon, C.B., Chen, M.X., Dora, K. A. and Garland, C.J. (2006) Evidence for involvement of both IKCa and SKCa channels in hyperpolarizing responses of the rat middle cerebral artery. Stroke, 37 (5). pp. 1277-1282. ISSN 0039-2499 doi: 10.1161/01.STR.0000217307.71231.43 McNeish, A. J., Dora, K. A. and Garland, C. J. (2005) Possible role for K+ in endothelium-derived hyperpolarizing factor–linked dilatation in rat middle cerebral artery. Stroke, 36 (7). pp. 1526-1532. ISSN 0039-2499 doi: 10.1161/01.STR.0000169929.66497.73 McNeish, A. J., Jimenez-Altayo, F., Cottrell, G. S. and Garland, C. J. (2012) Statins and selective inhibition of rho kinase protect small conductance calcium-activated potassium channel function (k(ca)2.3) in cerebral arteries. PLoS ONE, 7 (10). e46735. ISSN 1932-6203 doi: 10.1371/journal.pone.0046735 McNeish, A.J., Roux, B.T., Aylett, S.-B., Van Den Brink, A.M. and Cottrell, G.S. (2012) Endosomal proteolysis regulates calcitonin gene-related peptide responses in mesenteric arteries. British Journal of Pharmacology, 167 (8). pp. 1679-1690. ISSN 1476-5381 doi: 10.1111/j.1476-5381.2012.02129.x Mi, S., Chen, B., Wright, B. and Connon, C. J. (2010) Plastic compression of a collagen gel forms a much improved scaffold for ocular surface tissue engineering over conventional collagen gels. Journal of Biomedical Materials Research Part A, 95A (2). pp. 447-453. ISSN 1549-3296 doi: 10.1002/jbm.a.32861 Mi, S., David, A. L., Chowdhury, B., Jones, R. R., Hamley, I., Squires, A. and Connon, C. J. (2012) Tissue engineering a fetal membrane. Tissue Engineering Part A, 18 (3-4). pp. 373-381. ISSN 2152-4955 doi: 10.1089/ten.tea.2011.0194 Mi, S., Chen, B., Wright, B. and Connon, C. J. (2010) Ex Vivo Construction of an Artificial Ocular Surface by Combination of Corneal Limbal Epithelial Cells and a Compressed Collagen Scaffold Containing Keratocytes. Tissue Engineering, 16 (6). pp. 2091-2100. ISSN 1937-3341 doi: 10.1089/ten.TEA.2009.0748 Mi, S., Khutoryanskiy, V. V., Jones, R. R., Zhu, X., Hamley, I. W. and Connon, C. J. (2011) Photochemical cross-linking of plastically compressed collagen gel produces an optimal scaffold for corneal tissue engineering. Journal of Biomedical Materials Research Part A, 99A (1). pp. 1-8. ISSN 1549-3296 doi: 10.1002/jbm.a.33152 Milligan, C. J., Li, J., Sukumar, P., Majeed, Y., Dallas, M. L., English, A., Emery, P., Porter, K. E., Smith, A. M., McFadzean, I., Beccano-Kelly, D., Bahnasi, Y., Cheong, A., Naylor, J., Zeng, F., Liu, X., Gamper, N., Jiang, L.-H., Pearson, H. A., Peers, C., Robertson, B. and Beech, D. J. (2009) Robotic multiwell planar patch-clamp for native and primary mammalian cells. Nature Protocols, 4 (2). pp. 244-255. ISSN 1750-2799 doi: 10.1038/nprot.2008.230 Minguez Espallargas, G., van de Streek, J., Fernandes, P., Florence, A. J., Brunelli, M., Shankland, K. and Brammer, L. (2010) Mechanistic insights into a gas–solid reaction in molecular crystals: the role of hydrogen bonding. Angewandte Chemie International Edition, 49 (47). pp. 8892-8896. ISSN 1433-7851 doi: 10.1002/anie.201003265 Mitchell, C.E.T., Cobb, A.J.A. and Ley, S.V. (2005) A homo-proline tetrazole as an improved organocatalyst for the asymmetric Michael addition of carbonyl compounds to nitro-olefins. Synlett (4). pp. 611-614. ISSN 0936-5214 doi: 10.1055/s-2005-862392 Moore, S.A. and Mitchell, R.C., eds. (2008) Power, pedagogy and praxis: social justice in the globalized classroom. Critical issues in the future of learning and teaching, 1. Sense Publishers, Rotterdam. ISBN 9789087904906 Moreno-Fuquen, R., Valderrama-N, J., Shankland, K., Fabbiani, F.P.A. and Markvardsen, A.J. (2008) Three-centre hydrogen bonds in triphenylphosphine oxide-hydroquinone (1/1). Acta Crystallographica Section E, 64 (2). O367-U1679 . ISSN 1600-5368 doi: 10.1107/S1600536807067414 Morissette, M.R., Cook, S.A., Foo, S., McKoy, G., Ashida, N., Novikov, M., Scherrer-Crosbie, M., Li, L., Matsui, T., Brooks, G. and Rosenzweig, A. (2006) Myostatin regulates cardiomyocyte growth through modulation of Akt signaling. Circulation Research, 99 (1). pp. 15-24. ISSN 0009-7330 doi: 10.1161/01.RES.0000231290.45676.d4 Morris, C.J., Cantrill, J.A., Avery, A.J. and Howard, R.L. (2006) Preventing drug related morbidity: a process for facilitating changes in practice. Quality & Safety in Health Care, 15 (2). pp. 116-121. ISSN 1475-3898 doi: 10.1136/qshc.2005.014597 Morrison, P. W.J., Connon, C. J. and Khutoryanskiy, V. V. (2013) Cyclodextrin-mediated enhancement of riboflavin solubility and corneal permeability. Molecular Pharmaceutics, 10 (2). pp. 756-762. ISSN 1543-8392 doi: 10.1021/mp3005963 Moseley, F.L., Bicknell, K.A., Marber, M.S. and Brooks, G. (2007) The use of proteomics to identify novel therapeutic targets for the treatment of disease. Journal of Pharmacy and Pharmacology, 59 (5). pp. 609-628. ISSN 0022-3573 doi: 10.1211/jpp.59.5.0001 Movassagh, M., Bicknell, K. A. and Brooks, G. (2006) Characterisation and regulation of E2F-6 and E2F-6b in the rat heart: a potential target for myocardial regeneration? Journal of Pharmacy and Pharmacology, 58 (1). pp. 73-82. ISSN 0022-3573 doi: 10.1211/jpp.58.1.0009 Mueller, A., Mahmoud, N.G. and Strange, P.G. (2006) Diverse signalling by different chemokines through the chemokine receptor CCR5. Biochemical Pharmacology, 72 (6). pp. 739-748. ISSN 0006-2952 doi: 10.1016/j.bcp.2006.06.001 Mulgrew, C.J., A., C.-S., McLatchie, L.M., Brooks, G., Shattock, M.J. and Hendry, B.M. (2009) Inhibition of human mesangial cell proliferation by targeting T-Type calcium channels. Nephron Experimantal Nephrology, 113 (2). e77-e88. ISSN 1660-2129 doi: 10.1159/000232590 Mulheran, P. .A., Pellenc, D., Bennett, R. A., Green, R. J. and Sperrin, M. (2008) Mechanisms and dynamics of protein clustering on a solid surface. Physical Review Letters, 100 (6). 068102. ISSN 0031-9007 doi: 10.1103/PhysRevLett.100.068102 Mun, G.A., Nurkeeva, Z.S., Akhmetkalieva, G.T., Shmakov, S.N., Khutoryanskiy, V.V., Lee, S.C. and Park, K. (2006) Novel temperature-responsive water-soluble copolymers based on 2-hydroxyethylacrylate and vinyl butyl ether and their interactions with poly(carboxylic acids). Journal of Polymer Science Part B-Polymer Physics, 44 (1). pp. 195-204. ISSN 0887-6266 doi: 10.1002/polb.20695 Mun, G.A., Nurkeeva, Z.S., Beissegul, A.B., Dubolazov, A.V., Urkimbaeva, P.I., Park, K. and Khutoryanskiy, V.V. (2007) Temperature-responsive water-soluble copolymers based on 2-hydroxyethyl acrylate and butyl acrylate. Macromolecular Chemistry and Physics, 208 (9). pp. 979-987. ISSN 1022-1352 doi: 10.1002/macp.200600555 Müller-Bunz, H., Dix, I., Lou, Y., Pampillón, C., Strohfeldt, K., Sweeney, N.J. and Tacke, M. (2007) A series of novel 6-aryl fulvenes: impact of substitution on the phenyl ring, characterised by X-Ray crystallography. Zeitschrift Fur Kristallographie, 222 (7). pp. 376-382. ISSN 0044-2968 NNiemczyk, A. I., Williams, A. C., Rawlinson-Malone, C. F., Hayes, W., Greenland, B., Chappell, D. and Khutoryanskaya, O. (2012) Novel polyvinylpyrrolidones to improve delivery of poorly-water soluble drugs; from design to synthesis and evaluation. Molecular Pharmaceutics, 9 (8). pp. 2237-2247. ISSN 1543-8392 doi: 10.1021/mp300079x Nodes, W. J., Shankland, K., Rajkumar, S. and Cobb, A. J. A. (2010) Asymmetric phase-transfer-catalyzed synthesis of five-membered cyclic gamma-Amino acid precursors. Synlett , 2010 (20). pp. 3011-3014. ISSN 1437-2096 doi: 10.1055/s-0030-1259050 Nodes, W., Nutt, D. R., Chippindale, A. M. and Cobb, A. J. A. (2009) Enantioselective Intramolecular Michael Addition of Nitronates onto Conjugated Esters: Access to Cyclic γ-Amino Acids with up to Three Stereocenters. Journal of the American Chemical Society, 131 (44). pp. 16016-16017. ISSN 0002-7863 doi: 10.1021/ja9070915 Nurkeeva, Z.S., Mun, G.A., Dubolazov, A.V. and Khutoryanskiy, V.V. (2005) pH effects on the complexation, miscibility and radiation-induced crosslinking in poly(acrylic acid)-poly (vinyl alcohol) blends. Macromolecular Bioscience, 5 (5). pp. 424-432. ISSN 1616-5187 doi: 10.1002/mabi.200400200 Nurkeeva, Z.S., Mun, G.A., Sergaziev, A.D., Fefelova, N.A., Sarsenbaeva, A.S. and Khutoryanskiy, V.V. (2006) Synthesis of cationic water-soluble copolymers and hydrogels based on [2-(methacryloyloxy)ethyl]trimethylammonium cloride and 2-hydroxyethylacrylate and their complex formation with poly(acrylic acid). Journal of Polymer Science Part B-Polymer Physics, 44 (5). pp. 845-853. ISSN 0887-6266 doi: 10.1002/polb.20742 Nurkeeva, Z.S., Tyukova, I.S., Suvorova, A.I., Mun, G.A., Dzhusupbekova, A.B. and Khutoryanskiy, V.V. (2005) Miscibility studies in poly(methyl vinyl ether)/hydroxypropylcellulose binary system in aqueous solutions and solid state. Carbohydrate Polymers, 62 (1). pp. 80-86. ISSN 0144-8617 doi: 10.1016/j.carbpol.2005.06.023 OO'Brien, L. E., Timmins, P., Williams, A. and York, P. (2004) Use of in situ FT-Raman spectroscopy to study the kinetics of the transformation of carbamazepine polymorphs. Journal of Pharmaceutical and Biomedical Analysis, 36 (2). pp. 335-340. ISSN 0731-7085 doi: 10.1016/j.jpba.2004.06.024 O'Connor, K., Gill, C., Tacke, M., Rebmann, F.J.K., Strohfeldt, K., Sweeney, N., Fitzpatrick, J.M. and Watson, R.W.G. (2006) Novel titanocene anti-cancer drugs and their effect on apoptosis and the apoptotic pathway in prostate cancer cells. Apoptosis, 11 (7). pp. 1205-1214. ISSN 1360-8185 doi: 10.1007/s10495-006-6796-1 Oberschmidt, O., Hanauske, A.R., Pampillón, C., Strohfeldt, K., Sweeney, N.J. and Tacke, M. (2007) Antiproliferative activity of Titanocene Y against tumor colony-forming units. Anticancer Drugs, 18 (3). pp. 317-322. ISSN 0959-4973 doi: 10.1097/CAD.0b013e3280115f86 Oikonomopoulou, K., Hansen, K. K., Saifeddine, M., Tea, I., Blaber, M., Blaber, S. I., Scarisbrick, I., Andrade-Gordon, P., Cottrell, G. S., Bunnett, N. W., Diamandis, E. P. and Hollenberg, M. D. (2006) Proteinase-activated receptors, targets for kallikrein signaling. The Journal of Biological Chemistry, 281 (43). pp. 32095-32112. ISSN 1083-351X doi: 10.1074/jbc.M513138200 Osborn, H. M. I. and Turkson, A. (2009) Synthesis and NMR spectroscopic analysis of 3-nitro-pyranoside, 3-nitro-septanoside and 4-nitro-septanoside derivatives by condensation of the anion of nitromethane with glycoside. Tetrahedron Asymmetry, 20 (18). pp. 2162-2166. ISSN 0957-4166 doi: 10.1016/j.tetasy.2009.08.004 Osborn, H.M.I. (2005) Development of new methodologies for entry to targets of therapeutic interest. Synlett (17). pp. 2571-2586. ISSN 0936-5214 doi: 10.1055/s-2005-917076 Osborn, H.M.I. and Turkson, A. (2009) Sugars as pharmaceuticals. In: Gabius, H.-J. (ed.) The sugar code: fundamentals of glycosciences. Wiley-VCH, Weinheim, pp. 469-485. ISBN 9783527320899 Osborn, H.M.I., Evans, P.G. and Bezouska, K. (2008) Biomedicine of monosaccharides. In: Fraser-Reid, B.O., Tatsuta, K., Thiem, J., Coté, G.L., Flitsch, S., Ito, Y., Kondo, H., Nishimura, S.-i. and Yu, B. (eds.) Glycoscience: chemistry and chemical biology. Springer , Berlin, pp. 2399-2444. ISBN 9783540304296 Osborn, H.M.I., Meo, P. and Nijara, R.K. (2005) A new entry to 4,6-O-benzylidene glucal from phenyl 1-seleno-alpha-D-mannopyranoside. Tetrahedron-Asymmetry, 16 (11). pp. 1935-1937. ISSN 0957-4166 doi: 10.1016/j.tetasy.2005.05.004 Oswald, I. D. H., Lennie, A. R., Pulham, C. R. and Shankland, K. (2010) High-pressure structural studies of the pharmaceutical, chlorothiazide. Crystengcomm, 12 (9). pp. 2533-2540. ISSN 1466-8033 doi: 10.1039/c001355b Owen, R.E., Yamada, E., Thompson, C.I., Phillipson, L.J., Thompson, C., Taylor, E., Zambon, M., Osborn, H.M.I., Barclay, W.S. and Borrow, P. (2007) Alterations in receptor binding properties of recent human influenza H3N2 viruses are associated with reduced natural killer cell lysis of infected cells. Journal of Virology, 81 (20). pp. 11170-11178. ISSN 0022-538X doi: 10.1128/jvi.01217-07 PPadilla, B. E., Cottrell, G. S., Roosterman, D., Pikios, S., Muller, L., Steinhoff, M. and Bunnett, N. W. (2007) Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and beta-arrestins. Journal of Cell Biology, 179 (5). pp. 981-997. ISSN 0021-9525 doi: 10.1083/jcb.200704053 Pampillon, C., Claffey, J., Strohfeldt, K. and Tacke, M. (2008) Synthesis and cytotoxicity studies of new dimethylamino-functionalised and aryl-substituted titanocene anti-cancer agents. European Journal of Medicinal Chemistry, 43 (1). pp. 122-128. ISSN 0223-5234 doi: 10.1016/j.ejmech.2007.02.011 Pampillon, C., Mendoza, O., Sweeney, N.J., Strohfeldt, K. and Tacke, M. (2006) Diarylmethyl substituted titanocenes: promising anti-cancer drugs. Polyhedron, 25 (10). pp. 2101-2108. ISSN 0277-5387 doi: 10.1016/j.poly.2006.01.007 Pampillon, C., Sweeney, N.J., Strohfeldt, K. and Tacke, M. (2006) Diheteroarylmethyl substituted titanocenes: a novel class of possible anti-cancer drugs. Inorganica Chimica Acta, 359 (12). pp. 3969-3975. ISSN 0020-1693 doi: 10.1016/j.ica.2006.05.021 Pampillón, C., Claffey, J., Hogan, M., Strohfeldt, K. and Tacke, M. (2007) Synthesis and cytotoxicity studies of new dimethylamino-functionalised and indolyl-substituted titanocene anti-cancer drugs. Transition Metal Chemistry, 32 (4). pp. 434-441. ISSN 0340-4285 doi: 10.1007/s11243-006-0183-1 Pampillón, C., Sweeney, N.J., Strohfeldt, K. and Tacke, M. (2007) Synthesis and cytotoxicity studies of new dimethylamino-functionalised and hetero aryl-substituted titanocene anti-cancer drugs. Journal of Organometallic Chemistry, 692 (11). pp. 2153-2159. ISSN 022-328x doi: 10.1016/j.jorganchem.2007.01.045 Papadopoulou, A., Green, R. J. and Frazier, R. A. (2005) Interaction of flavonoids with bovine serum albumin: a fluorescence quenching study. Journal of Agricultural and Food Chemistry , 53 (1). pp. 158-163. ISSN 0021-8561 doi: 10.1021/jf048693g Parker, S. F., Refson, K., Tavender, S. M., Albers, P., Hannebauer, B., Janik, M., Muller, A., Martens, J., Watzke, M., Shankland, K., Leech, C. and Offermanns, H. (2009) Vibrational spectroscopy of a compound with a CS7 ring. Journal of Raman Spectroscopy, 40 (6). pp. 703-708. ISSN 0377-0486 doi: DOI:10.1002/jrs.2270 Pasut, G., Greco, F., Mero, A., Mendichi, R., Fante, C., Green, R. J. and Veronese, F. (2009) Polymer-drug conjugates for combination anticancer therapy: investigating the mechanism of action. Journal of Medicinal Chemistry, 52 (20). pp. 6499-6502. ISSN 0022-2623 doi: 10.1021/jm900804m Patani, R., Lewis, P. A., Trabzuni, D., Puddifoot, C. A., Wyllie, D. J. A., Walker, R., Smith, C., Hardingham, G. E., Weale, M., Hardy, J., Chandran, S. and Ryten, M. (2012) Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis. Journal of Neurochemistry, 122 (4). pp. 738-751. ISSN 0022-3042 doi: 10.1111/j.1471-4159.2012.07825.x Patel, N. A., Weston, S. E., Constanti, A., Halliwell, J. V. and Whalley, B. J. (2007) Cholinergic modulation of intrinsic fibre-evoked excitatory transmission contains a nicotinic component in immature but not adult rat piriform cortex, in vitro. Neuroscience Letters, 425 (1). pp. 43-48. ISSN 0304-3940 doi: 10.1016/j.neulet.2007.08.005 Peacey, E., Miller, C. C., Dunlop, J. and Rattray, M. (2009) The four major N- and C-terminal splice variants of the excitatory amino acid transporter GLT-1 form cell surface homomeric and heteromeric assemblies. Molecular Pharmacology, 75 (5). pp. 1062-1073. ISSN 1521-0111 Peers, C., Bauer, C. C., Boyle, J. P., Scragg, J. L. and Dallas, M. L. (2012) Modulation of ion channels by hydrogen sulfide. Antioxidants & Redox Signaling, 17 (1). pp. 95-105. ISSN 1523-0864 Peers, C., Dallas, M. L. and Scragg, J. L. (2009) Ion channels as effectors in carbon monoxide signaling. Communicative & Integrative Biology, 2 (3). pp. 241-242. ISSN 1942-0889 doi: 10.1074/jbc.M8030372 Peers, C., Dallas, M. L., Boycott, H. E., Scragg, J. L., Pearson, H. A. and Boyle, J. P. (2009) Hypoxia and neurodegeneration. In: Peers, C., Haddad, G. G. and Chandel, N. S. (eds.) Hypoxia and Consequences: From Molecule to Malady. Annals of the New York Academy of Sciences (1177). New York Academy of Sciences, New York, pp. 169-177. Pellenc, D., Bennett, R. A., Green, R. G., Sperrin, M. and Mulheran, P. A. (2008) New insights on growth mechanisms of protein clusters at surfaces: an AFM and simulation study. Langmuir, 24 (17). pp. 9648-9655. ISSN 0743-7463 doi: 10.1021/la801246k Pepys, M.B., Hirschfield, G.M., Tennent, G.A., Gallimore, J.R., Kahan, M.C., Bellotti, V., Hawkins, P.N., Myers, R.M., Smith, M.D., Polara, A., Cobb, A.J.A., Ley, S.V., Aquilina, J.A., Robinson, C.V., Sharif, I., Gray, G.A., Sabin, C.A., Jenvey, M.C., Kolstoe, S.E., Thompson, D. and Wood, S.P. (2006) Targeting C-reactive protein for the treatment of cardiovascular disease. Nature, 440 (7088). pp. 1217-1221. ISSN 0028-0836 doi: 10.1038/nature04672 Priestley, C.M., Burgess, I.F. and Williamson, E.M. (2006) Lethality of essential oil constituents towards the human louse, Pediculus humanus, and its eggs. Fitoterapia, 77 (4). pp. 303-309. ISSN 0367-326X doi: 10.1016/j.fitote.2006.04.005 Putnam, S.E., Scutt, A.M., Bicknell, K., Priestley, C.M. and Williamson, E.M. (2007) Natural products as alternative treatments for metabolic bone disorders and for maintenance of bone health. Phytotherapy Research, 21 (2). pp. 99-112. ISSN 0951-418X doi: 10.1002/ptr.2030 QQu, X.Z., Khutoryanskiy, V.V., Stewart, A., Rahman, S., Papahadjopoulos-Sternberg, B., Dufes, C., McCarthy, D., Wilson, C.G., Lyons, R., Carter, K.C., Schatzlein, A. and Uchegbu, I.F. (2006) Carbohydrate-based micelle clusters which enhance hydrophobic drug bioavailability by up to 1 order of magnitude. Biomacromolecules, 7 (12). pp. 3452-3459. ISSN 1525-7797 doi: 10.1021/bm0604000 Quirk, K., Roberts, D.J. and Strange, P.G. (2007) Mechanisms of G protein activation via the D-2 dopamine receptor: evidence for persistent receptor/G protein interaction after agonist stimulation. British Journal of Pharmacology, 151 (1). pp. 125-133. ISSN 0007-1188 doi: 10.1038/sj.bjp.0707197 RRainey-Smith, S. R., Andersson, D. A., Williams, R. J. and Rattray, M. (2010) Tumour necrosis factor alpha induces rapid reduction in AMPA receptor-mediated calcium entry in motor neurones by increasing cell surface expression of the GluR2 subunit: relevance to neurodegeneration. Journal of Neurochemistry, 113 (3). pp. 692-703. ISSN 0022-3042 doi: 10.1111/j.1471-4159.2010.06634.x Rainey-Smith, S., Schroetke, L.W., Bahia, P., Fahmi, A., Skilton, R., Spencer, J.P.E., Rice-Evans, C., Rattray, M. and Williams, R.J. (2008) Neuroprotective effects of hesperetin in mouse primary neurones are independent of CREB activation. Neuroscience Letters, 438 (1). pp. 29-33. ISSN 0304-3940 doi: 10.1016/j.neulet.2008.04.056 Rajkumar, S., Shankland, K., Goodman, J. M. and Cobb, A. J.A. (2013) Organocatalytic domino reaction of cyanosulfones: access to complex cyclohexane systems with quaternary carbon centers. Organic Letters. ISSN 1523-7060 doi: 10.1021/ol400356k Rajkumar, S., Shankland, K., Brown, G. D. and Cobb, A. (2012) Organocatalytic enantioselective construction of nitrocyclohexanes containing multiple chiral centres via a cascade reaction. Chemical Science, 3. pp. 584-588. ISSN 1478-6524 doi: 10.1039/C1SC00592H Rangam, G., Schmitz, K.-M., Cobb, A. and Petersen-Mahrt, S. (2012) AID enzymatic activity is inversely proportional to the size of cytosine C5 orbital cloud. PloS ONE, 7 (8). e43279. ISSN 1932-6203 doi: 10.1371/journal.pone.0043279 Rankin-Box, D. and Williamson, E.M. (2006) Complementary medicine: a guide for pharmacists. Churchill Livingstone Elsevier, London. ISBN 9780443070280 Rattray, M. (2012) New insights on regulation of LMTK2, a membrane kinase integrating pathways central to neurodegeneration. Journal of Neurochemistry. doi: 10.1111/j.1471-4159.2012.07654.x (In Press) Rattray, M. (2005) Technology evaluation: Colostrinin (ReGen). Current Opinion in Molecular Therapeutics, 7 (1). pp. 78-84. ISSN 1464-8431 Rattray, M. and Bendotti, C. (2006) Does excitotoxic cell death of motor neurons in ALS arise from glutamate transporter and glutamate receptor abnormalities? Experimental Neurology, 201 (1). pp. 15-23. ISSN 0014-4886 doi: 10.1016/j.expneurol.2006.05.001 Rawlinson, C.F., Williams, A.C., Timmins, P. and Grimsey, I. (2007) Polymer-mediated disruption of drug crystallinity. International Journal of Pharmaceutics, 336 (1). pp. 42-48. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2006.11.029 Reed, D. E., Barajas-Lopez, C., Cottrell, G. S., Velazquez-Rocha, S., Dery, O., Grady, E. F., Bunnett, N. W. and Vanner, S. J. (2003) Mast cell tryptase and proteinase-activated receptor 2 induce hyperexcitability of guinea-pig submucosal neurons. Journal of Physiology, 547 (2). pp. 531-542. ISSN 0022-3751 doi: 10.1113/jphysiol.2002.032011 Reed, M.L., Dove, B.K., Jackson, R.M., Collins, R., Brooks, G. and Hiscox, J.A. (2006) Delineation and modelling of a nucleolar retention signal in the coronavirus nucleocapsid protein. Traffic, 7 (7). pp. 833-848. ISSN 1398-9219 doi: 10.1111/j.1600-0854.2006.00424.x Rendeiro, C., Vauzour, D., Kean, R. J., Butler, L. T., Rattray, M., Spencer, J. P. E. and Williams, C. M. (2012) Blueberry supplementation induces spatial memory improvements and region-specific regulation of hippocampal BDNF mRNA expression in young rats. Psychopharmacology, 223 (3). pp. 319-330. ISSN 0033-3158 doi: 10.1007/s00213-012-2719-8 Rizi, K., Green, B., Donaldson, M. and Williams, A. (2011) Production of pH-responsive microparticles by spray drying: investigation of experimental parameter effects on morphological and release properties. Journal of Pharmaceutical Sciences, 100 (2). pp. 566-579. ISSN 1520-6017 doi: 10.1002/jps.22291 Rizi, K., Green, R. J., Donaldson, M. X. and Williams, A. C. (2011) Using pH abnormalities in diseased skin to trigger and target topical therapy. Pharmaceutical Research, 28 (10). pp. 2589-2598. ISSN 0724-8741 doi: 10.1007/s11095-011-0488-4 Rizi, K., Green, R. J., Khutoryanskaya, O., Donaldson, M. and Williams, A. C. (2011) Mechanisms of burst release from pH-responsive polymeric microparticles. Journal of Pharmacy and Pharmacology, 63 (9). pp. 1141-1155. ISSN 0022-3573 doi: 10.1111/j.2042-7158.2011.01322.x Roberts, D.J. and Strange, P.G. (2005) Mechanisms of inverse agonist action at D-2 dopamine receptors. British Journal of Pharmacology, 145 (1). pp. 34-42. ISSN 0007-1188 doi: 10.1038/sj.bjp.0706073 Roosterman, D., Cottrell, G. S., Padilla, B. E., Muller, L., Eckman, C. B., Bunnett, N. W. and Steinhoff, M. (2007) Endothelin-converting enzyme 1 degrades neuropeptides in endosomes to control receptor recycling. Proceedings of the National Academy of Sciences of the United States of America, 104 (28). pp. 11838-11843. ISSN 0027-8424 doi: 10.1073/pnas.0701910104 Roosterman, D., Cottrell, G. S., Schmidlin, F., Steinhoff, M. and Bunnett, N. W. (2004) Recycling and resensitization of the neurokinin 1 receptor: influence of agonist concentration and Rab GTPases. The Journal of Biological Chemistry, 279 (29). pp. 30670-30679. ISSN 1083-351X doi: 10.1074/jbc.M402479200 Roosterman, D., Kreuzer, O. J., Brune, N., Cottrell, G. S., Bunnett, N. W., Meyerhof, W. and Steinhoff, M. (2007) Agonist-induced endocytosis of rat somatostatin receptor 1. Endocrinology, 148 (3). pp. 1050-1058. ISSN 1945-7170 doi: 10.1210/en.2006-1600 Rovira, X., Vivo, M., Serra, J., Roche, D., Strange, P.G. and Giraldo, J. (2009) Modelling the interdependence between the stoichiometry of receptor oligomerization and ligand binding for a coexisting dimer/tetramer receptor system. British Journal of Pharmacology, 156 (1). pp. 28-35. ISSN 0007-1188 doi: 10.1111/j.1476-5381.2008.00031.x SSadler, S., Rodgers, S., Howard, R., Morris, C. J. and Avery, A. J. (2013) Training pharmacists to deliver a complex information technology intervention (PINCER) using the principles of educational outreach and root cause analysis. International Journal of Pharmacy Practice. ISSN 0961-7671 doi: 10.1111/ijpp.12032 Sarsam, S. W., Nutt, D. R., Strohfeldt, K. and Watson, K. A. (2011) Titanocene anticancer complexes and their binding mode of action to human serum albumin: a computational study. Metallomics, 3 (2). pp. 152-161. ISSN 1756-5901 doi: 10.1039/c0mt00041h Saslis Lagoudakis, C.H., Savolainen, V., Williamson, L., Forest, F., Wagstaff, S., Baral, S.R., Watson, M., Pendry, C. and Hawkins, J. (2012) Phylogenies reveal predictive power of traditional medicine in bioprospecting. Proceedings of the National Academy of Sciences of the United States of America, 109 (39). pp. 15835-15840. ISSN 1091-6490 doi: 10.1073/pnas.1202242109 Schroeter, H., Bahia, P., Spencer, J.P.E., Sheppard, O., Rattray, M., Cadenas, E., Rice-Evans, C. and Williams, R.J. (2007) (-)Epicatechin stimulates ERK-dependent cyclic AMP response element activity and up-regulates GluR2 in cortical neurons. Journal of Neurochemistry, 101 (6). pp. 1596-1606. ISSN 0022-3042 doi: 10.1111/j.1471-4159.2006.04434.x Scragg, J. L., Dallas, M. L. and Peers, C. (2007) Molecular requirements for L-type Ca2+ channel blockade by testosterone. Cell Calcium, 42 (1). pp. 11-15. ISSN 0143-4160 doi: 10.1016/j.ceca.2006.11.003 Scragg, J. L., Dallas, M. L., Wilkinson, J. A., Varadi, G. and Peers, C. (2008) Carbon monoxide inhibits L-type Ca2+ channels via redox modulation of key cysteine residues by mitochondrial reactive oxygen species. The Journal of Biological Chemistry, 283 (36). pp. 24412-24419. ISSN 1083-351X doi: 10.1074/jbc.M803037200 Scutt, A. and Williamson, E.M. (2007) Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors. Calcified Tissue International, 80 (1). pp. 50-59. ISSN 0171-967X doi: 10.1007/s00223-006-0171-7 Shah, P., Donyai, P. and Williamson, E. M. (2010) Students’ perception of the safety and value of a herbal vs. a conventional medicine for treating insomnia. International Journal of Pharmacy Practice, 17 (S2). B91-B92. ISSN 0961-7671 doi: DOI:10.1211/096176709789037155 Shaikh, A. K., Cobb, A. J. A. and Varvounis, G. (2012) Mild and rapid method for the generation of ortho-(naphtho)-quinone methide intermediates. Organic Letters, 14 (2). pp. 584-587. ISSN 1523-7060 doi: 10.1021/ol203196n Shankland, K., Markvardsen, A. J., Rowlatt, C., Shankland, N. and David, W. I. F. (2010) A benchmark method for global optimization problems in structure determination from powder diffraction data. Journal of Applied Crystallography, 43 (3). pp. 401-406. ISSN 0021-8898 doi: 10.1107/S0021889810008113 Shaw, D., Ladds, G., Duez, P., Williamson, E. and Chan, K. (2012) Pharmacovigilance of herbal medicines. Journal of Ethnopharmacology, 140 (3). pp. 513-518. ISSN 0378-8741 doi: 10.1016/j.jep.2012.01.051 Singh, S., Gras, A., Fiez-Vandal, C., Ruprecht, J., Rana, R., Martinez, M., Strange, P. G., Wagner, R. and Byrne, B. (2008) Large-scale functional expression of WT and truncated human adenosine A(2A) receptor in Pichia pastoris bioreactor cultures. Microbial Cell Factories, 7. p. 10. ISSN 1475-2859 doi: 10.1186/1475-2859-7-28 Smart, P., Mason, C. A., Loader, J. R., Meijer, A. J. H. M., Florence, A. J., Shankland, K., Fletcher, A. J., Thompson, S. P., Brunelli, M., Hill, A. H. and Brammer, L. (2013) Zipping and unzipping of a paddlewheel metal-organic framework to enable two-step synthetic and structural transformation. Chemistry- A European Journal, 19 (11). pp. 3552-3557. ISSN 1521-3765 doi: 10.1002/chem.201204492 Smith, E. C. J., Williamson, E. M., Wareham, N., Kaatz, G. W. and Gibbons, S. (2007) Antibacterials and modulators of bacterial resistance from the immature cones of Chamaecyparis lawsoniana. Phytochemistry, 68 (2). pp. 210-217. ISSN 0031-9422 doi: 10.1016/j.phytochem.2006.10.001 Smith, E., Williamson, E.M., Zloh, M. and Gibbons, S. (2005) Isopimaric acid from Pinus nigra shows activity against multidrug-resistant and EMRSA strains of Staphylococcus aureus. Phytotherapy Research, 19 (6). pp. 538-542. ISSN 0951-418X doi: 10.1002/ptr.1711 Sogias, I., Khutoryanskiy, V. V. and Williams, A. C. (2010) Exploring the Factors Affecting the Solubility of Chitosan in Water. Macromolecular Chemistry and Physics, 211 (4). pp. 426-433. ISSN 1022-1352 doi: 10.1002/macp.200900385 Sogias, I., Williams, A. C. and Khutoryanskiy, V. V. (2008) Why is Chitosan Mucoadhesive? Biomacromolecules, 9 (7). pp. 1837-1842. ISSN 1525-7797 doi: 10.1021/bm800276d Sogias, I., Williams, A. and Khutoryanskiy, V. (2012) Chitosan-based mucoadhesive tablets for oral delivery of ibuprofen. International Journal of Pharmaceutics, 436 (1-2). pp. 602-610. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2012.07.007 Spilsbury, A., Vauzour, D., Spencer, J. P. and Rattray, M. (2012) Regulation of NF-κB activity in astrocytes: effects of flavonoids at dietary-relevant concentrations. Biochemical and Biophysical Research Communications, 418. pp. 578-583. ISSN 0006-291X doi: 10.1016/j.bbrc.2012.01.081 Spyridon, M., Moraes, L. A., Jones, C. I., Sage, T., Sasikumar, P., Bucci, G. and Gibbins, J. M. (2011) LXR as a novel antithrombotic target. Blood, 117 (21). pp. 5751-5761. ISSN 1528-0020 doi: 10.1182/blood-2010-09-306142 Steinmeyer, R., Noskov, A., Krasel, C., Weber, I., Dees, C. and Harms, G.S. (2005) Improved fluorescent proteins for single-molecule research in molecular tracking and co-localization. Journal of Fluorescence, 15 (5). pp. 707-721. ISSN 1053-0509 doi: 10.1007/s10895-005-2978-4 Stephens, G. J. (2009) G-protein-coupled-receptor-mediated presynaptic inhibition in the cerebellum. Trends in Pharmacological Sciences, 30 (8). 421-430 . ISSN 01656147 doi: 10.1016/j.tips.2009.05.008 Stephens, G.J. and Mochida, S. (2005) G protein ss gamma subunits mediate presynaptic inhibition of transmitter release from rat superior cervical ganglion neurones in culture. Journal of Physiology, 563 (3). pp. 765-776. ISSN 0022-3751 doi: 10.1113/jphysiol.2004.080192 Strange, P. (2008) Clinically unproven. LabLit.com. Strange, P. (2008) Conference nightmares. LabLit.com. Strange, P. (2008) Hard cell. LabLit.com. Strange, P. (2008) Heat of the moment. LabLit.com. Strange, P. (2008) Professor brain booster. BBC Focus Magazine. Strange, P. (2008) Putting the coke in coke. The Naked Scientists: Science Radio & Science Podcasts. Strange, P. G. (2008) Agonist binding, agonist affinity and agonist efficacy at G protein-coupled receptors. British Journal of Pharmacology, 153 (7). pp. 1353-1363. ISSN 0007-1188 doi: 10.1038/sj.bjp.0707672 Strange, P. G. (2008) Antipsychotic drug action: antagonism, inverse agonism or partial agonism. Trends in Pharmacological Sciences, 29 (6). pp. 314-321. ISSN 0165-6147 doi: 10.1016/j.tips.2008.03.009 Strange, P. G. (2008) Signaling mechanisms of GPCR ligands. Current Opinion in Drug Discovery & Development, 11 (2). pp. 196-202. ISSN 1367-6733 Strange, P.G. (2007) Mechanisms underlying agonist efficacy. Biochemical Society Transactions, 35 (4). pp. 733-736. ISSN 0300-5127 Strange, P.G. (2005) Oligomers of D-2 dopamine receptors: evidence from ligand binding. Journal of Molecular Neuroscience, 26 (2-3). pp. 155-159. ISSN 0895-8696 doi: 10.1385/JMN/26:02:155 Strohfeldt, K. and Grant, D. T. (2010) A model for self-directed problem-based learning for renal therapeutics. American Journal of Pharmaceutical Education , 74 (9). Article 173. Strohfeldt, K. A. and Tacke, M. (2008) Bioorganometallic fulvene-derived titanocene anti-cancer drugs. Chemical Society Reviews, 37 (6). pp. 1174-1187. ISSN 0306-0012 doi: DOI:10.1039/b707310k Strohfeldt, K., Muller-Bunz, H., Pampillon, C., Sweeney, N.J. and Tacke, M. (2006) Glycol methyl ether and glycol amine substituted titanocenes as antitumor agents. European Journal of Inorganic Chemistry (22). pp. 4621-4628. ISSN 1434-1948 doi: 10.1002/ejic.200600586 Strohfeldt, K., Müller-Bunz, H., Pampillon, C. and Tacke, M. (2007) Proliferative and antiproliferative effects in substituted titanocene anticancer drugs. Transition Metal Chemistry, 32 (7). pp. 971-980. ISSN 0340-4285 doi: 10.1007/s11243-007-0265-8 Strohmann, C., Dilsky, S. and Strohfeldt, K. (2006) Crystal structures of [PhLi center dot(-)-sparteine](2), [PhOLi center dot(-)-sparteine](2), and the mixed aggregate [PhLi center dot PhOLi center dot 2(-)-sparteine]. Organometallics, 25 (1). pp. 41-44. ISSN 0276-7333 doi: 10.1021/om050794w Suchak, S., Baloyianni, N., Perkinton, M., Williams, R., Meldrum, B. and Rattray, M. (2003) The 'glial' glutamate transporter, EAAT2 (Glt-1) accounts for high affinity glutamate uptake into adult rodent nerve endings. Journal of Neurochemistry, 84 (3). pp. 522-532. ISSN 0022-3042 doi: 10.1046/j.1471-4159.2003.01553.x Sweeney, N., Gallagher, W.M., Muller-Bunz, H., Pampillon, C., Strohfeldt, K. and Tacke, M. (2006) Heteroaryl substituted titanocenes as potential anti-cancer drugs. Journal of Inorganic Biochemistry, 100 (9). pp. 1479-1486. ISSN 0162-0134 doi: 10.1016/j.jinorgbio.2006.04.006 Sweeney, N.J., Claffey, J., Müller-Bunz, H., Pampillon, C., Strohfeldt, K. and Tacke, M. (2007) The synthesis and cytotoxic evaluation of a series of benzodioxole substituted titanocenes. Applied Organometallic Chemistry, 21 (2). pp. 57-65. ISSN 0268-2605 doi: 10.1002/aoc.1177 Sznitowska, M., Janicki, S. and Williams, A. C. (1998) Intracellular or intercellular localization of the polar pathway of penetration across stratum corneum. Journal of Pharmaceutical Sciences, 87 (9). pp. 1109-1114. ISSN 1520-6017 doi: 10.1021/js980018w TTekko, I.A., Bonner, M.C. and Williams, A.C. (2006) An optimized reverse-phase high performance liquid chromatographic method for evaluating percutaneous absorption of glucosamine hydrochloride. Journal of Pharmaceutical and Biomedical Analysis, 41 (2). pp. 385-392. ISSN 0731-7085 doi: 10.1016/j.jpba.2005.11.044 Tekko, I.A., Bonner, M.C., Bowen, R.D. and Williams, A.C. (2006) Permeation of bioactive constituents from Arnica montana preparations through human skin in-vitro. Journal of Pharmacy and Pharmacology, 58 (9). pp. 1167-1176. ISSN 0022-3573 doi: 10.1211/jpp.58.9.0002 Thomas, L. H., Craig, G. A., Gutmann, M. J., Parkin, A., Shankland, K. and Wilson, C. C. (2011) Conformational polymorphism of the molecular complex of 3-fluorobenzoic acid with 4-acetylpyridine. CrystEngComm, 13 (10). pp. 3349-3354. ISSN 1466-8033 doi: 10.1039/c1ce05139c Thomas, S., McDowell, S., Hodson, J., Nwulu, U., Howard, R., Avery, A., Slee, A. and Coleman, J. (2013) Developing consensus on hospital prescribing indicators of potential harms amenable to decision support. British Journal of Clinical Pharmacology. ISSN 0306-5251 (In Press) Todd, S., Baksh, M. F. and Whitehead, J. (2012) Sequential methods for pharmacogenetic studies. Computational Statistics & Data Analysis, 56 (5). pp. 1221-1231. ISSN 0167-9473 doi: 10.1016/j.csda.2011.02.019 Tortarolo, M., Crossthwaite, A.J., Conforti, L., Spencer, J.P.E., Williams, R.J. , Bendotti, C. and Rattray, M. (2004) Expression of SOD1 G93A or wild-type SOD1 in primary cultures of astrocytes down-regulates the glutamate transporter GLT-1: lack of involvement of oxidative stress. Journal of Neurochemistry, 88 (2). pp. 481-493. ISSN 0022-3042 doi: 10.1046/j.1471-4159.2003.02208.x Trevisani, M., Siemens, J., Materazzi, S., Bautista, D. M., Nassini, R., Campi, B., Imamachi, N., Andre, E., Patacchini, R., Cottrell, G. S., Gatti, R., Basbaum, A. I., Bunnett, N. W., Julius, D. and Geppetti, P. (2007) 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proceedings of the National Academy of Sciences of the United States of America, 104 (33). pp. 13519-13524. ISSN 0027-8424 doi: 10.1073/pnas.0705923104 UUpton, R., Graff, A., Jolliffe, G., Laenger, R. and Williamson, E., eds. (2011) American Herbal Pharmacopoeia: botanical pharmacognosy - microscopic characterization of botanical medicines. American Herbal Pharmacopoeia/CRC Press, Boca Raton, pp773. ISBN 9781420073263 Uzuner, H., Bauer, R., Fan, T.-P., Guo, D.-a., Dias, A., El-Nezami, H., Efferth, T., Williamson, E. M., Heinrich, M., Robinson, N., Hylands, P. J., Hendry, B. M., Cheng, Y.-C. and Xu, Q. (2012) Traditional Chinese medicine research in the post-genomic era: good practice, priorities, challenges and opportunities. Journal of Ethnopharmacology, 140 (3). pp. 458-468. ISSN 0378-8741 doi: 10.1016/j.jep.2012.02.028 VValadares, M.C., Ramos, A.L., Rehmann, F.J.K., Sweeney, N.J., Strohfeldt, K., Tacke, M. and Queiroz, M.L.S. (2006) Antitumour activity of [1,2-di(cyclopentadienyl)-1,2-di(p-N,N-dimethylaminophenyl)-ethanediyl] titanium dichloride in xenografted Ehrlich's ascites tumour. European Journal of Pharmacology, 534 (1-3). pp. 264-270. ISSN 0014-2999 doi: 10.1016/j.ejphar.2006.01.056 Van den Berg, M. and Donyai, P. (2010) How was patient empowerment portrayed in information leaflets describing the community pharmacy Medicines Use Review service in the UK? Patient Education and Counseling, 80 (2). pp. 274-276. ISSN 0738-3991 doi: 10.1016/j.pec.2009.11.013 Vauzour, D., Spilsbury, A., Vafeiadou, K., Rattray, M. and Spencer, J. (2012) Modulation of neuroinflammation by dietary flavonoids. In: Gemma, C. (ed.) Neuroinflammation: Pathogenesis, Mechanisms and Management. Nova. ISBN 9781619424623 (In Press) Vessieres, A., Plamont, M.-A., Cabestaing, C., Claffey, J., Dieckmann, S., Hogan, M., Mueller-Bunz, H., Strohfeldt, K. A. and Tacke, M. (2009) Proliferative and anti-proliferative effects of titanium- and iron-based metallocene anti-cancer drugs. Journal of Organometallic Chemistry , 694 (6). pp. 874-879. ISSN 0022-328X doi: 10.1016/j.jorganchem.2008.11.071 Vicent, M. J., Greco, F., Nicholson, R. I., Paul, A., Griffiths , P. C. and Duncan, R. (2005) Polymer therapeutics designed for a combination therapy of hormone-dependent cancer. Angewandte Chemie-International Edition, 44 (26). pp. 4061-4066. ISSN 1521-3773 doi: 10.1002/anie.200462960 Vivo, M. and Strange, P.G. (2005) Cooperativity in ligand binding to deduce receptor-receptor interaction. In: George, S.R. and O' Dowd, B.F. (eds.) G protein-coupled receptor-protein interactions. Receptor biochemistry and methodology. Wiley-Liss, Hoboken, New Jersey, pp. 19-36. ISBN 9780471235460 Vivo, M., Lin, H. and Strange, P.G. (2005) Investigation of cooperativity in the binding of ligands to the D-2 dopamine receptor. Molecular Pharmacology, 69 (1). pp. 226-235. ISSN 0026-895X doi: 10.1124/mol.105.012443 Vogl, C., Mochida, S., Wolff, C., Whalley, B. and Stephens, G. (2012) The SV2A ligand levetiracetam inhibits presynaptic Ca2+ channels via an intracellular pathway. Molecular Pharmacology, 82 (2). pp. 199-208. ISSN 1521-0111 doi: 10.1124/mol.111.076687 van den Berg, M. and Donyai, P. (2007) Uptake of a free coronary heart disease risk screening programme in community pharmacy: the Healthy Heart Assessment service. International Journal of Pharmacy Practice, 15 (Supplement 2). B18-B19. ISSN 0961-7671 doi: DOI:10.1211/096176707781890761 van den Berg, M. and Donyai, P. (2010) What is the new medicines use review ‘patient survey’ attempting to capture in the context of existing patient satisfaction with pharmacy questionnaires and a new conceptual framework? International Journal of Pharmacy Practice, 18 (S1). pp. 40-41. ISSN 0961-7671 doi: DOI:10.1111/j.2042-7174.2010.00040.x van den Berg, M. and Donyai, P. (2010) A retrospective audit of medicines use review forms. International Journal of Pharmacy Practice, 18 (S1). pp. 33-34. ISSN 0961-7671 doi: 10.1111/j.2042-7174.2010.00027.x WWang, X., Horswill, J. G., Whalley, B. J. and Stephens, G. J. (2011) Effects of the Allosteric Antagonist 1-(4-Chlorophenyl)-3-[3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl]urea (PSNCBAM-1) on CB1 Receptor Modulation in the Cerebellum. Molecular Pharmacology, 79 (4). pp. 758-767. ISSN 1521-0111 doi: 10.1124/mol.110.068197 Warwick, K., Xydas, D., Nasuto, S. J., Becerra, V. M., Hammond, M. W., Downes, J., Marshall, S. and Whalley, B. J. (2010) Controlling a mobile robot with a biological brain. Defence Science Journal, 60 (1). pp. 5-14. ISSN 0011-748X Weston, S. E., Williamson, E. M., Constanti, A., Stephens, G. J. and Whalley, B. J. (2006) Tetrahydrocannabivarin exhibits anticonvulsant effects in a piriform cortical brain slice model of epileptiform activity. In: British Pharmacological Society Winter Meeting 2006. Weston, S.E. (2009) Asian medicine. In: Evans, W.C. (ed.) Trease and Evans' pharmacognosy. Saunders Ltd., London, pp. 498-503. ISBN 9780702029332 Weston, S.E., Whalley, B.J., Wilkinson, J.D. and Williamson, E.M. (2007) Medicinal cannabis: new findings on extracts and minor cannabinoids. In: Capasso, A. (ed.) Recent developments in medicinal plant research. Research Signpost, Trivandrum, Kerala, India, pp. 39-62. ISBN 9788130801605 Whalley, B. J. and Constanti, A. (2006) Developmental changes in presynaptic muscarinic modulation of excitatory and inhibitory neurotransmission in rat piriform cortex in vitro: relevance to epileptiform bursting susceptibility. Neuroscience, 140 (3). pp. 939-956. ISSN 0306-4522 doi: 10.1016/j.neuroscience.2006.02.046 Whalley, B. J., Postlethwaite, M. and Constanti, A. (2005) Further characterization of muscarinic agonist-induced epileptiform bursting activity in immature rat piriform cortex, in vitro. Neuroscience, 134 (2). pp. 549-566. ISSN 0306-4522 doi: 10.1016/j.neuroscience.2005.04.018 Whalley, B. J., Stephens, G. J. and Constanti, A. (2009) Investigation of the effects of the novel anticonvulsant compound carisbamate(RWJ-333369) on rat piriform cortical neurones in vitro. British Journal of Pharmacology, 156 (6). pp. 994-1008. ISSN 0007-1188 doi: 10.1111/j.1476-5381.2008.00110.x Whalley, B. J., Wilkinson, J. D., Williamson, E. M. and Constanti, A. (2004) A novel component of cannabis extract potentiates excitatory synaptic transmission in rat olfactory cortex in vitro. Neuroscience Letters, 365 (1). pp. 58-63. ISSN 0304-3940 doi: 10.1016/j.neulet.2004.04.044 Whalley, B.J., Fletcher, K.E., Weston, S.E., Howard, R.L. and Rawlinson, C.F. (2008) Foundation in pharmacy practice. Pharmaceutical, London. ISBN 9780853697473 Wilkinson, J. D. and Williamson, E. M. (2007) Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis. Journal of Dermatological Science, 45 (2). pp. 87-92. ISSN 0923-1811 doi: 10.1016/j.jdermsci.2006.10.009 Wilkinson, J. N. and Donyai, P. (2009) Participation of future pharmacists in a professional development certificate scheme; the paradox of personal identity. International Journal of Pharmacy Practice, 17 (S1). A36-A37. ISSN 0961-7671 doi: DOI:10.1211/096176709787640652 Wilkinson, J., Cairns, C. and Donyai, P. (2008) The professional development certificate scheme for undergraduates. The Pharmaceutical Journal, 281. 393 . ISSN 0031-6873 Wilkinson, J.D., Whalley, B. J., Baker, D., Pryce, G., Constanti, A., Gibbons, S. and Williamson, E. M. (2003) Medicinal cannabis: is delta9-tetrahydrocannabinol necessary for all its effects? Journal of Pharmacy and Pharmacology, 55 (12). pp. 1687-1694. ISSN 0022-3573 doi: DOI:10.1211/0022357022304 Williams, A. C., Cooper, V. B., Thomas, L., Griffith, L. J., Petts, C. R. and Booth, S. W. (2004) Evaluation of drug physical form during granulation, tabletting and storage. International Journal of Pharmaceutics, 275 (1-2). pp. 29-39. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2004.01.042 Williams, A. C., Edwards, H. G. M., Lawson, E. E. and Barry, B. W. (2006) Molecular interactions between the penetration enhancer 1,8-cineole and human skin. Journal of Raman Spectroscopy, 37 (1-3). pp. 361-366. ISSN 0377-0486 doi: 10.1002/jrs.1468 Williams, A. C., Timmins, P., Lu, M. C. and Forbes, R. T. (2005) Disorder and dissolution enhancement: Deposition of ibuprofen on to insoluble polymers. European Journal of Pharmaceutical Sciences, 26 (3-4). pp. 288-294. ISSN 0928-0987 doi: 10.1016/j.ejps.2005.06.006 Williamson, E. M. (2007) The medicinal use of essential oils and their components for treating lice and mite infestations. Natural Product Communications, 2 (12). pp. 1303-1310. ISSN 1934-578X Williamson, E. M., Priestley, C. M. and Burgess, I. F. (2007) An investigation and comparison of the bioactivity of selected essential oils on human lice and house dust mites. Fitoterapia, 78 (7-8). pp. 521-525. ISSN 0367-326X doi: 10.1016/j.fitote.2007.06.001 Williamson, E., Driver, S. and Baxter, K., eds. (2009) Stockley’s herbal medicines interactions : a guide to the interactions of herbal medicines, dietary supplements, and nutraceuticals with conventional medicines. Pharmaceutical Press, London, pp431. ISBN 9780853697602 Williamson, E.M. (2005) Interactions between herbal and conventional medicines. Expert Opinion on Drug Safety, 4 (2). pp. 355-378. ISSN 1474-0338 doi: 10.1517/14740338.4.2.355 Williamson, E.M. (2009) Synergy and other interactions in phytomedicines. In: Evans, W.C. (ed.) Trease and Evans' pharmacognosy. Saunders Ltd., London, pp. 53-61. ISBN 9780702029332 Williamson, E.M. , Driver, S. and Baxter, K., eds. (2009) Stockley's herbal medicines interactions. Pharmaceutical Press, London. ISBN 9780853697602 Williamson, E.M. and Rankin-Box, D. (2009) Complementary therapies, the placebo effect and the pharmacist. Complementary Therapies in Clinical Practice, 15 (3). pp. 172-179. ISSN 1744-3881 doi: 10.1016/j.ctcp.2009.06.001 Winstel, R., Ihlenfeldt, H.G., Jung, G., Krasel, C. and Lohse, M.J. (2005) Peptide inhibitors of G protein-coupled receptor kinases. Biochemical Pharmacology, 70 (7). pp. 1001-1008. ISSN 0006-2952 doi: 10.1016/j.bcp.2005.06.012 Wright, B., Mi, S. and Connon, C. J. (2012) Towards the use of hydrogels in the treatment of limbal stem cell deficiency. Drug Discovery Today, 18 (1-2). pp. 79-86. ISSN 1359-6446 doi: 10.1016/j.drudis.2012.07.012 Wright, B., Cave, R. A., Cook, J. P., Khutoryanskiy, V. V., Mi, S., Chen, B., Leyland, M. and Connon, C. J. (2012) Enhanced viability of corneal epithelial cells for efficient transport/storage using a structurally-modified calcium alginate hydrogel. Regenerative Medicine, 7 (3). pp. 295-307. ISSN 1746-076X doi: 10.2217/rme.12.7 YYang, L. and Stephens, G. J. (2009) Effects of neuropathy on high-voltage-activated Ca2+ current in sensory neurones. Cell Calcium, 46 (4). 248-256 . ISSN 01434160 doi: 10.1016/j.ceca.2009.08.001 Yin, J. B., Luo, K., Chen, X. S. and Khutoryanskiy, V. V. (2006) Miscibility studies of the blends of chitosan with some cellulose ethers. Carbohydrate Polymers, 63 (2). pp. 238-244. ISSN 0144-8617 doi: 10.1016/j.carbpol.2005.08.041 Yuill, K. H., McNeish, A., Kansui, Y., Garland, C. J. and Dora , K. A. (2010) Nitric oxide suppresses cerebral vasomotion by sGC-independent effects on ryanodine receptors and voltage-gated calcium channels. Journal of Vascular Research, 47 (2). pp. 93-107. ISSN 1018-1172 doi: 10.1159/000235964 ZZhunuspayev, D., Mun, G. and Khutoryanskiy, V. V. (2010) Temperature-responsive properties and drug solubilization capacity of amphiphilic copolymers based on N-vinylpyrrolidone and vinyl propyl ether. Langmuir, 26 (10). pp. 7590-7597. ISSN 1520-5827 doi: 10.1021/la904403k Zhunuspayev, D., Mun, G., Hole, P. and Khutoryanskiy, V. V. (2008) Solvent Effects on the Formation of Nanoparticles and Multilayered Coatings Based on Hydrogen-Bonded Interpolymer Complexes of Poly(acrylic acid) with Homo- and Copolymers of N-Vinyl Pyrrolidone. Langmuir, 24 (23). pp. 13742-13747. ISSN 0743-7463 doi: DOI:10.1021/la802852h ÖÖsterlind, M.L., Denicolo, P. and Johansson, C.R. (2007) Head teachers caught in the middle or on top of things? In: Aili, C., Nilsson, L.E., Svensson, L.G. and Denicolo, P. (eds.) In tension between organization and profession: professionals in Nordic public service. Nordic Academic Press., Lund, pp. 133-153. ISBN 9789185509027 |
